Published in J Ind Microbiol Biotechnol on March 06, 2010
Insights into naturally minimised Streptomyces albus J1074 genome. BMC Genomics (2014) 1.15
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity. Nat Prod Rep (2010) 1.15
Strain improvement in actinomycetes in the postgenomic era. J Ind Microbiol Biotechnol (2011) 1.07
Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes. J Ind Microbiol Biotechnol (2015) 0.90
Bioactive oligosaccharide natural products. Nat Prod Rep (2014) 0.89
Strain-level diversity of secondary metabolism in Streptomyces albus. PLoS One (2015) 0.89
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biol (2013) 0.87
Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. J Am Chem Soc (2017) 0.86
Complex transcriptional control of the antibiotic regulator afsS in Streptomyces: PhoP and AfsR are overlapping, competitive activators. J Bacteriol (2011) 0.84
Antibacterial Discovery and Development: From Gene to Product and Back. Biomed Res Int (2015) 0.81
ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export. Arch Microbiol (2012) 0.81
Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects. J Antibiot (Tokyo) (2016) 0.80
Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity. Nat Commun (2015) 0.79
Identification and characterization of the Streptomyces globisporus 1912 regulatory gene lndYR that affects sporulation and antibiotic production. Microbiology (2011) 0.78
MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway. Mol Microbiol (2013) 0.76
Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production. Russ J Genet (2014) 0.75
Generation and study of the strains of streptomycetes - heterologous hosts for production of moenomycin. Russ J Genet (2014) 0.75
Discovering potential Streptomyces hormone producers by using disruptants of essential biosynthetic genes as indicator strains. J Antibiot (Tokyo) (2017) 0.75
Basic local alignment search tool. J Mol Biol (1990) 659.07
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Natl Acad Sci U S A (2000) 96.90
Identifying bacterial genes and endosymbiont DNA with Glimmer. Bioinformatics (2007) 47.63
Regulation of secondary metabolism in streptomycetes. Curr Opin Microbiol (2005) 3.45
Structural insight into the transglycosylation step of bacterial cell-wall biosynthesis. Science (2007) 2.99
afsR is a pleiotropic but conditionally required regulatory gene for antibiotic production in Streptomyces coelicolor A3(2). Mol Microbiol (1996) 2.22
Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2). J Bacteriol (1996) 2.03
Streptomyces albus G mutants defective in the SalGI restriction-modification system. J Gen Microbiol (1980) 1.84
The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives. Chem Biol (2002) 1.75
Cross-regulation among disparate antibiotic biosynthetic pathways of Streptomyces coelicolor. Mol Microbiol (2005) 1.69
Bacterial transglycosylase inhibitors. Curr Opin Chem Biol (2005) 1.51
A streamlined metabolic pathway for the biosynthesis of moenomycin A. Chem Biol (2007) 1.47
Inhibition of transglycosylation involved in bacterial peptidoglycan synthesis. Curr Med Chem (2000) 1.40
Genetic manipulation of antibiotic-producing Streptomyces. Trends Microbiol (1998) 1.34
afsR2: a previously undetected gene encoding a 63-amino-acid protein that stimulates antibiotic production in Streptomyces lividans. Mol Microbiol (1994) 1.28
The total synthesis of moenomycin A. J Am Chem Soc (2006) 1.23
Amplification of the entire kanamycin biosynthetic gene cluster during empirical strain improvement of Streptomyces kanamyceticus. Proc Natl Acad Sci U S A (2006) 1.21
Functional analysis of relA and rshA, two relA/spoT homologues of Streptomyces coelicolor A3(2). J Bacteriol (2001) 1.19
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. ACS Chem Biol (2008) 1.19
Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry (2009) 1.19
Phosphorylated AbsA2 negatively regulates antibiotic production in Streptomyces coelicolor through interactions with pathway-specific regulatory gene promoters. J Bacteriol (2007) 1.12
Genome-wide transcriptome analysis reveals that a pleiotropic antibiotic regulator, AfsS, modulates nutritional stress response in Streptomyces coelicolor A3(2). BMC Genomics (2008) 1.12
Antibacterial activity of synthetic analogues based on the disaccharide structure of moenomycin, an inhibitor of bacterial transglycosylase. Microbiology (2000) 1.08
Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136. FEMS Microbiol Lett (2008) 1.05
A gene transfer system for the glycopeptide producer Nonomuraea sp. ATCC39727. FEMS Microbiol Lett (2003) 0.92
Characterization of a negative regulator AveI for avermectin biosynthesis in Streptomyces avermitilis NRRL8165. Appl Microbiol Biotechnol (2008) 0.88
Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids. Plasmid (2009) 0.88
[Analysis of genome rearrangements in Streptomyces kanamyceticus mutants]. Antibiot Khimioter (1998) 0.79
Effect of a global regulatory gene, afsR2, from Streptomyces lividans on avermectin production in Streptomyces avermitilis. J Biosci Bioeng (2000) 0.78
The bacterial cell envelope. Cold Spring Harb Perspect Biol (2010) 5.14
Lipoprotein cofactors located in the outer membrane activate bacterial cell wall polymerases. Cell (2010) 2.53
Imaging peptidoglycan biosynthesis in Bacillus subtilis with fluorescent antibiotics. Proc Natl Acad Sci U S A (2006) 2.53
Discovery of O-GlcNAc transferase inhibitors. J Am Chem Soc (2005) 2.27
Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes. J Biol Chem (2003) 2.26
Structure of human O-GlcNAc transferase and its complex with a peptide substrate. Nature (2011) 2.24
Wall teichoic acid function, biosynthesis, and inhibition. Chembiochem (2010) 2.15
Crystal structure of the MurG:UDP-GlcNAc complex reveals common structural principles of a superfamily of glycosyltransferases. Proc Natl Acad Sci U S A (2003) 2.02
Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate. Proc Natl Acad Sci U S A (2003) 1.96
In vitro reconstitution of two essential steps in wall teichoic acid biosynthesis. ACS Chem Biol (2006) 1.89
Wall teichoic acids of gram-positive bacteria. Annu Rev Microbiol (2013) 1.77
Crystal structure of a peptidoglycan glycosyltransferase suggests a model for processive glycan chain synthesis. Proc Natl Acad Sci U S A (2007) 1.68
Synthetic lethal compound combinations reveal a fundamental connection between wall teichoic acid and peptidoglycan biosyntheses in Staphylococcus aureus. ACS Chem Biol (2010) 1.64
Remarkable structural similarities between diverse glycosyltransferases. Chem Biol (2002) 1.56
A revised pathway proposed for Staphylococcus aureus wall teichoic acid biosynthesis based on in vitro reconstitution of the intracellular steps. Chem Biol (2008) 1.52
Bacterial transglycosylase inhibitors. Curr Opin Chem Biol (2005) 1.51
A streamlined metabolic pathway for the biosynthesis of moenomycin A. Chem Biol (2007) 1.47
Intrinsic lipid preferences and kinetic mechanism of Escherichia coli MurG. Biochemistry (2002) 1.44
Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics. Proc Natl Acad Sci U S A (2010) 1.42
Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2. J Bacteriol (2005) 1.41
Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proc Natl Acad Sci U S A (2012) 1.39
Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. ACS Chem Biol (2009) 1.37
Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. J Am Chem Soc (2011) 1.37
Analysis of glycan polymers produced by peptidoglycan glycosyltransferases. J Biol Chem (2007) 1.36
Synthesis of heptaprenyl-lipid IV to analyze peptidoglycan glycosyltransferases. J Am Chem Soc (2007) 1.35
Cutaneous metastases in breast cancer. Clin J Oncol Nurs (2011) 1.30
The direction of glycan chain elongation by peptidoglycan glycosyltransferases. J Am Chem Soc (2007) 1.28
Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II. J Am Chem Soc (2003) 1.24
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics. J Am Chem Soc (2005) 1.23
Late-stage polyribitol phosphate wall teichoic acid biosynthesis in Staphylococcus aureus. J Bacteriol (2008) 1.22
HCF-1 is cleaved in the active site of O-GlcNAc transferase. Science (2013) 1.21
The mechanism of action of ramoplanin and enduracidin. Mol Biosyst (2005) 1.21
Identification of active-site inhibitors of MurG using a generalizable, high-throughput glycosyltransferase screen. J Am Chem Soc (2003) 1.20
Structural snapshots of the reaction coordinate for O-GlcNAc transferase. Nat Chem Biol (2012) 1.20
Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design. ACS Chem Biol (2008) 1.19
Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry (2009) 1.19
Forming cross-linked peptidoglycan from synthetic gram-negative Lipid II. J Am Chem Soc (2013) 1.18
Expression and characterization of the isolated glycosyltransferase module of Escherichia coli PBP1b. Biochemistry (2004) 1.17
Generation of new landomycins by combinatorial biosynthetic manipulation of the LndGT4 gene of the landomycin E cluster in S. globisporus. Chem Biol (2004) 1.17
Insights into naturally minimised Streptomyces albus J1074 genome. BMC Genomics (2014) 1.15
Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity. Nat Prod Rep (2010) 1.15
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides. J Am Chem Soc (2005) 1.13
The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. J Am Chem Soc (2010) 1.11
Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms. J Am Chem Soc (2013) 1.10
Isolated peptidoglycan glycosyltransferases from different organisms produce different glycan chain lengths. J Am Chem Soc (2008) 1.09
Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents. Chem Biol (2013) 1.07
Acceptor substrate selectivity and kinetic mechanism of Bacillus subtilis TagA. Biochemistry (2006) 1.06
Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136. FEMS Microbiol Lett (2008) 1.05
O-linked N-acetylglucosaminyltransferase inhibition prevents G2/M transition in Xenopus laevis oocytes. J Biol Chem (2007) 1.04
Identification of selective inhibitors for the glycosyltransferase MurG via high-throughput screening. Chem Biol (2004) 1.02
A neutral diphosphate mimic crosslinks the active site of human O-GlcNAc transferase. Nat Chem Biol (2011) 1.02
Rethinking ramoplanin: the role of substrate binding in inhibition of peptidoglycan biosynthesis. J Am Chem Soc (2002) 1.01
Reconstitution of peptidoglycan cross-linking leads to improved fluorescent probes of cell wall synthesis. J Am Chem Soc (2014) 1.00
Generation of novel landomycins M and O through targeted gene disruption. Chembiochem (2005) 0.99
An antibiotic that inhibits a late step in wall teichoic acid biosynthesis induces the cell wall stress stimulon in Staphylococcus aureus. Antimicrob Agents Chemother (2012) 0.98
Decoupling catalytic activity from biological function of the ATPase that powers lipopolysaccharide transport. Proc Natl Acad Sci U S A (2014) 0.98
Substrate analogues to study cell-wall biosynthesis and its inhibition. Curr Opin Chem Biol (2002) 0.97
Teichoic acid biosynthesis as an antibiotic target. Curr Opin Microbiol (2013) 0.97
Detection of lipid-linked peptidoglycan precursors by exploiting an unexpected transpeptidase reaction. J Am Chem Soc (2014) 0.97
Development of improved inhibitors of wall teichoic acid biosynthesis with potent activity against Staphylococcus aureus. Bioorg Med Chem Lett (2010) 0.97
A strategy to discover inhibitors of O-linked glycosylation. J Am Chem Soc (2007) 0.96
Two distinct mechanisms for TIM barrel prenyltransferases in bacteria. J Am Chem Soc (2011) 0.96
Dissecting ramoplanin: mechanistic analysis of synthetic ramoplanin analogues as a guide to the design of improved antibiotics. J Am Chem Soc (2004) 0.94
Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry. J Am Chem Soc (2011) 0.94
ABC transporters required for export of wall teichoic acids do not discriminate between different main chain polymers. ACS Chem Biol (2011) 0.93
Synthesis of mono- and disaccharide analogs of moenomycin and lipid II for inhibition of transglycosylase activity of penicillin-binding protein 1b. Bioorg Med Chem (2004) 0.92
In vitro antimicrobial activity of wall teichoic acid biosynthesis inhibitors against Staphylococcus aureus isolates. Antimicrob Agents Chemother (2010) 0.92
Studying a cell division amidase using defined peptidoglycan substrates. J Am Chem Soc (2009) 0.91
Streptomyces ghanaensis pleiotropic regulatory gene wblA(gh) influences morphogenesis and moenomycin production. Biotechnol Lett (2011) 0.90
Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis. Chembiochem (2004) 0.90
Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway. J Am Chem Soc (2004) 0.90
On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2). Angew Chem Int Ed Engl (2006) 0.89
Role of wall teichoic acids in Staphylococcus aureus endophthalmitis. Invest Ophthalmol Vis Sci (2011) 0.89
Phase 2 trial of maintenance bevacizumab alone after bevacizumab plus pemetrexed and carboplatin in advanced, nonsquamous nonsmall cell lung cancer. Cancer (2012) 0.88
Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids. Plasmid (2009) 0.88
Primer preactivation of peptidoglycan polymerases. J Am Chem Soc (2011) 0.87
Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biol (2013) 0.87
Complete genome sequence of producer of the glycopeptide antibiotic Aculeximycin Kutzneria albida DSM 43870T, a representative of minor genus of Pseudonocardiaceae. BMC Genomics (2014) 0.86
Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways. Chem Biol (2010) 0.86
Non-proteinogenic amino acids in lacticin 481 analogues result in more potent inhibition of peptidoglycan transglycosylation. ACS Chem Biol (2012) 0.86
Modular synthesis of diphospholipid oligosaccharide fragments of the bacterial cell wall and their use to study the mechanism of moenomycin and other antibiotics. Tetrahedron (2011) 0.86