Published in Eur J Immunol on January 01, 2006
Modulation of adaptive immunity with Toll-like receptors. Semin Immunol (2009) 2.56
Sensing of viral infection and activation of innate immunity by toll-like receptor 3. Clin Microbiol Rev (2008) 2.39
TLR3 immunity to infection in mice and humans. Curr Opin Immunol (2013) 1.22
TRAF molecules in cell signaling and in human diseases. J Mol Signal (2013) 1.22
Regulation of TLR7/9 signaling in plasmacytoid dendritic cells. Protein Cell (2012) 1.05
Genome-wide association and genomic prediction for host response to porcine reproductive and respiratory syndrome virus infection. Genet Sel Evol (2014) 1.02
Toll-like receptors in skin infections and inflammatory diseases. Infect Disord Drug Targets (2008) 0.99
Predicting novel features of toll-like receptor 3 signaling in macrophages. PLoS One (2009) 0.89
Hyaluronic acid oligosaccharides suppress TLR3-dependent cytokine expression in a TLR4-dependent manner. PLoS One (2013) 0.82
7-Ketocholesterol-induced inflammation signals mostly through the TLR4 receptor both in vitro and in vivo. PLoS One (2014) 0.81
RNA-sequence analysis of primary alveolar macrophages after in vitro infection with porcine reproductive and respiratory syndrome virus strains of differing virulence. PLoS One (2014) 0.80
Nuclear factor κB2 p52 protein has a role in antiviral immunity through IκB kinase epsilon-dependent induction of Sp1 protein and interleukin 15. J Biol Chem (2013) 0.80
A novel long non-coding RNA in the rheumatoid arthritis risk locus TRAF1-C5 influences C5 mRNA levels. Genes Immun (2015) 0.80
Characterization of bbtTICAM from amphioxus suggests the emergence of a MyD88-independent pathway in basal chordates. Cell Res (2011) 0.78
A new domain in the Toll/IL-1R domain-containing adaptor inducing interferon-β factor protein amino terminus is important for tumor necrosis factor-α receptor-associated factor 3 association, protein stabilization and interferon signaling. J Innate Immun (2014) 0.75
Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution. Cell Stem Cell (2007) 21.58
VISA is an adapter protein required for virus-triggered IFN-beta signaling. Mol Cell (2005) 14.20
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. Cell Stem Cell (2009) 8.62
The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation. Immunity (2008) 7.60
Single-cell exome sequencing and monoclonal evolution of a JAK2-negative myeloproliferative neoplasm. Cell (2012) 5.16
Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes. Science (2010) 4.60
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci U S A (2009) 4.46
Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF. Immunity (2004) 4.00
Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates. Nature (2009) 2.81
Epigenetic reprogramming by adenovirus e1a. Science (2008) 2.38
Sir2 deacetylates histone H3 lysine 56 to regulate telomeric heterochromatin structure in yeast. Mol Cell (2007) 2.38
The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA. Immunity (2009) 2.21
Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways. J Biol Chem (2004) 2.16
PCBP2 mediates degradation of the adaptor MAVS via the HECT ubiquitin ligase AIP4. Nat Immunol (2009) 2.07
A20 is a potent inhibitor of TLR3- and Sendai virus-induced activation of NF-kappaB and ISRE and IFN-beta promoter. FEBS Lett (2004) 1.98
Charcot-Marie-Tooth disease-associated mutant tRNA synthetases linked to altered dimer interface and neurite distribution defect. Proc Natl Acad Sci U S A (2007) 1.91
Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement. Mol Cell (2009) 1.84
Structural insights into the catalytic mechanism of cyclophilin A. Nat Struct Biol (2003) 1.78
An improved recombineering approach by adding RecA to lambda Red recombination. Mol Biotechnol (2006) 1.75
IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma. Biochem Biophys Res Commun (2011) 1.74
Ligand-receptor binding revealed by the TNF family member TALL-1. Nature (2003) 1.70
RFECS: a random-forest based algorithm for enhancer identification from chromatin state. PLoS Comput Biol (2013) 1.66
TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis. J Biol Chem (2004) 1.65
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. J Biol Chem (2002) 1.60
ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response. Proc Natl Acad Sci U S A (2009) 1.60
SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways. EMBO J (2005) 1.58
The return periods and risk assessment of severe dust storms in Inner Mongolia with consideration of the main contributing factors. Environ Monit Assess (2011) 1.56
TIRP, a novel Toll/interleukin-1 receptor (TIR) domain-containing adapter protein involved in TIR signaling. J Biol Chem (2003) 1.52
TNFR-associated factor-3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kappa B activation and IL-10 production. J Immunol (2002) 1.50
Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients. Lung Cancer (2010) 1.49
Management of the first confirmed case of avian influenza A H7N9. Respir Care (2013) 1.45
Study of stone composition changes in melamine-related urinary calculi and its clinical significance. Urology (2011) 1.44
Glycogen synthase kinase 3β regulates IRF3 transcription factor-mediated antiviral response via activation of the kinase TBK1. Immunity (2010) 1.39
Tripartite motif 8 (TRIM8) modulates TNFα- and IL-1β-triggered NF-κB activation by targeting TAK1 for K63-linked polyubiquitination. Proc Natl Acad Sci U S A (2011) 1.36
Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3. Cell Res (2008) 1.35
Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase. Proc Natl Acad Sci U S A (2007) 1.35
Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6. J Biol Chem (2009) 1.34
TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination. J Biol Chem (2012) 1.33
FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation. Proc Natl Acad Sci U S A (2009) 1.32
Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore. J Biol Chem (2008) 1.30
Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT6-dependent process. J Exp Med (2003) 1.28
SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. J Mol Cell Biol (2011) 1.28
Lamin B receptor plays a role in stimulating nuclear envelope production and targeting membrane vesicles to chromatin during nuclear envelope assembly through direct interaction with importin beta. J Cell Sci (2007) 1.26
Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response. J Biol Chem (2010) 1.25
Electrolyte-gated transistors for organic and printed electronics. Adv Mater (2012) 1.23
Comparing early outbreak detection algorithms based on their optimized parameter values. J Biomed Inform (2009) 1.22
Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization. J Biol Chem (2008) 1.21
The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation. J Immunol (2010) 1.21
p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties. Mol Cell Biol (2010) 1.21
Activation of human TRPC6 channels by receptor stimulation. J Biol Chem (2004) 1.21
Neurexin-1 is required for synapse formation and larvae associative learning in Drosophila. FEBS Lett (2007) 1.20
AMID, an apoptosis-inducing factor-homologous mitochondrion-associated protein, induces caspase-independent apoptosis. J Biol Chem (2002) 1.20
Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer. Gigascience (2012) 1.18
Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms. Cell Res (2012) 1.16
The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IkappaB kinase family members. J Immunol (2006) 1.16
RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation. J Biol Chem (2007) 1.15
Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex. J Biol Chem (2009) 1.14
LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection. Proc Natl Acad Sci U S A (2012) 1.14
Identification of uteroglobin-related protein 1 and macrophage scavenger receptor with collagenous structure as a lung-specific ligand-receptor pair. J Immunol (2003) 1.13
The landscape of accessible chromatin in mammalian preimplantation embryos. Nature (2016) 1.13
Different clinical significance of pre- and post-treatment plasma Epstein-Barr virus DNA load in nasopharyngeal carcinoma treated with radiotherapy. Clin Oncol (R Coll Radiol) (2010) 1.12
MicroRNA-181a suppresses salivary adenoid cystic carcinoma metastasis by targeting MAPK-Snai2 pathway. Biochim Biophys Acta (2013) 1.11
SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription. J Biol Chem (2003) 1.11
Expression of transient receptor potential C6 and related transient receptor potential family members in human airway smooth muscle and lung tissue. Am J Respir Cell Mol Biol (2003) 1.10
Benefits and costs of immunizing children against influenza at school: an economic analysis based on a large-cluster controlled clinical trial. Health Aff (Millwood) (2008) 1.10
RIP5 is a RIP-homologous inducer of cell death. Biochem Biophys Res Commun (2004) 1.09
Noxa/Mcl-1 balance regulates susceptibility of cells to camptothecin-induced apoptosis. Neoplasia (2007) 1.09
A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma. BMC Med (2010) 1.08
WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation. Proc Natl Acad Sci U S A (2009) 1.08
Accurate cancer classification using expressions of very few genes. IEEE/ACM Trans Comput Biol Bioinform (2007) 1.07
Identification of downstream genes up-regulated by the tumor necrosis factor family member TALL-1. J Leukoc Biol (2002) 1.07
cis-N,N-Bis(2-hy-droxy-benzyl-idene)cyclo-hexane-1,2-diamine. Acta Crystallogr Sect E Struct Rep Online (2011) 1.06
Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity. J Hepatol (2013) 1.06
Regulation of IRF2 transcriptional activity by its sumoylation. Biochem Biophys Res Commun (2008) 1.05
Regulation of DNA methylation turnover at LTR retrotransposons and imprinted loci by the histone methyltransferase Setdb1. Proc Natl Acad Sci U S A (2014) 1.04
SLCO1B1 521T-->C functional genetic polymorphism and lipid-lowering efficacy of multiple-dose pravastatin in Chinese coronary heart disease patients. Br J Clin Pharmacol (2007) 1.04
Curcumin modulates miR-19/PTEN/AKT/p53 axis to suppress bisphenol A-induced MCF-7 breast cancer cell proliferation. Phytother Res (2014) 1.04
Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment. Proc Natl Acad Sci U S A (2013) 1.03
Modularity of the Hrd1 ERAD complex underlies its diverse client range. J Cell Biol (2010) 1.02
Investigating the links between the subcomponents of executive function and academic achievement: a cross-cultural analysis of Chinese and American preschoolers. J Exp Child Psychol (2011) 1.02
NIK is a component of the EGF/heregulin receptor signaling complexes. Oncogene (2003) 1.01
Long-term high-fat diet induces pancreatic injuries via pancreatic microcirculatory disturbances and oxidative stress in rats with hyperlipidemia. Biochem Biophys Res Commun (2006) 1.01
Prevalence of birth defects and risk-factor analysis from a population-based survey in Inner Mongolia, China. BMC Pediatr (2012) 1.01
Microfluidic fabrication of asymmetric giant lipid vesicles. ACS Appl Mater Interfaces (2011) 1.01
TRIP6 is a RIP2-associated common signaling component of multiple NF-kappaB activation pathways. J Cell Sci (2005) 1.01