Published in Hum Mol Genet on December 08, 2005
Vesicular monoamine transporter 2: role as a novel target for drug development. AAPS J (2006) 1.78
Increased vesicular monoamine transporter enhances dopamine release and opposes Parkinson disease-related neurodegeneration in vivo. Proc Natl Acad Sci U S A (2014) 1.63
The Drosophila vesicular monoamine transporter reduces pesticide-induced loss of dopaminergic neurons. Neurobiol Dis (2010) 1.31
VMAT2-Deficient Mice Display Nigral and Extranigral Pathology and Motor and Nonmotor Symptoms of Parkinson's Disease. Parkinsons Dis (2011) 1.07
Experimenting with spirituality: analyzing The God Gene in a nonmajors laboratory course. CBE Life Sci Educ (2008) 1.01
Animal models of the non-motor features of Parkinson's disease. Neurobiol Dis (2012) 1.00
Vesicular monoamine transporters: structure-function, pharmacology, and medicinal chemistry. Med Res Rev (2010) 0.99
PACAP38 increases vesicular monoamine transporter 2 (VMAT2) expression and attenuates methamphetamine toxicity. Neuropeptides (2008) 0.98
Computational systems analysis of dopamine metabolism. PLoS One (2008) 0.96
Analysis of vesicular monoamine transporter 2 polymorphisms in Parkinson's disease. Neurobiol Aging (2013) 0.94
Reduced vesicular storage of catecholamines causes progressive degeneration in the locus ceruleus. Neuropharmacology (2013) 0.93
Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene. PLoS One (2009) 0.93
Edaravone guards dopamine neurons in a rotenone model for Parkinson's disease. PLoS One (2011) 0.88
Monoamine transporters: vulnerable and vital doorkeepers. Prog Mol Biol Transl Sci (2011) 0.87
Vesicular monoamine transporter 2 mRNA levels are reduced in platelets from patients with Parkinson's disease. J Neural Transm (Vienna) (2010) 0.87
Associations among types of impulsivity, substance use problems and neurexin-3 polymorphisms. Drug Alcohol Depend (2011) 0.87
The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse. Adv Pharmacol (2014) 0.87
Pesticides that inhibit the ubiquitin-proteasome system: effect measure modification by genetic variation in SKP1 in Parkinson׳s disease. Environ Res (2013) 0.85
High regulatability favors genetic selection in SLC18A2, a vesicular monoamine transporter essential for life. FASEB J (2010) 0.84
Rho GTPase regulation of α-synuclein and VMAT2: implications for pathogenesis of Parkinson's disease. Mol Cell Neurosci (2011) 0.83
Computational analysis of determinants of dopamine (DA) dysfunction in DA nerve terminals. Synapse (2009) 0.83
N-terminus regulation of VMAT2 mediates methamphetamine-stimulated efflux. Neuroscience (2013) 0.82
Vesicular integrity in Parkinson's disease. Curr Neurol Neurosci Rep (2013) 0.82
In vivo beta-cell imaging with VMAT 2 ligands--current state-of-the-art and future perspective. Curr Pharm Des (2010) 0.81
Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression. Mol Psychiatry (2012) 0.78
Brain serotonergic circuitries. Dialogues Clin Neurosci (2010) 0.78
VMAT2 and Parkinson's disease: harnessing the dopamine vesicle. Expert Rev Neurother (2014) 0.78
Reduced vesicular monoamine transport disrupts serotonin signaling but does not cause serotonergic degeneration. Exp Neurol (2015) 0.77
Genetic Variation in the Vesicular Monoamine Transporter: Preliminary Associations With Cognitive Outcomes After Severe Traumatic Brain Injury. J Head Trauma Rehabil (2016) 0.77
Vesicular Monoamine Transporter 2 (VMAT2) Level Regulates MPTP Vulnerability and Clearance of Excess Dopamine in Mouse Striatal Terminals. Toxicol Sci (2016) 0.76
Membrane transporters as mediators of synaptic dopamine dynamics: implications for disease. Eur J Neurosci (2016) 0.76
hVMAT2: A Target of Individualized Medication for Parkinson's Disease. Neurotherapeutics (2016) 0.75
Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease. Proc Natl Acad Sci U S A (2017) 0.75
Genetic elimination of dopamine vesicular stocks in the nigrostriatal pathway replicates Parkinson's disease motor symptoms without neuronal degeneration in adult mice. Sci Rep (2017) 0.75
A new statistical method for haplotype reconstruction from population data. Am J Hum Genet (2001) 59.30
What features improve the accuracy of clinical diagnosis in Parkinson's disease: a clinicopathologic study. Neurology (1992) 6.03
Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity. Am J Epidemiol (2003) 5.00
Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science (2001) 4.48
Multiple comparison procedures updated. Clin Exp Pharmacol Physiol (1998) 3.92
Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990. Neurology (1999) 2.62
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter. Cell (1992) 2.58
Risk factors for Parkinson's disease. Neurology (1993) 2.47
Are men at greater risk for Parkinson's disease than women? J Neurol Neurosurg Psychiatry (2004) 2.47
VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proc Natl Acad Sci U S A (1997) 2.34
Screening a large reference sample to identify very low frequency sequence variants: comparisons between two genes. Nat Genet (2001) 2.07
Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action. Neuron (1997) 1.83
Differential expression of two vesicular monoamine transporters. J Neurosci (1995) 1.75
In vivo positron emission tomographic evidence for compensatory changes in presynaptic dopaminergic nerve terminals in Parkinson's disease. Ann Neurol (2000) 1.65
A population-based investigation of Parkinson's disease with and without dementia. Relationship to age and gender. Arch Neurol (1992) 1.59
The role of vesicular transport proteins in synaptic transmission and neural degeneration. Annu Rev Neurosci (1997) 1.42
Coffee consumption, gender, and Parkinson's disease mortality in the cancer prevention study II cohort: the modifying effects of estrogen. Am J Epidemiol (2004) 1.31
Risk of Parkinson's disease among first-degree relatives: A community-based study. Neurology (1996) 1.30
Gender differences in Parkinson's disease symptom profile. Acta Neurol Scand (2000) 1.30
Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism. Mol Cell Biol (2001) 1.24
Gene transfer of a reserpine-sensitive mechanism of resistance to N-methyl-4-phenylpyridinium. Proc Natl Acad Sci U S A (1992) 1.23
Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice. J Neurochem (1998) 1.23
The impact of gender and estrogen on striatal dopaminergic neurotoxicity. Ann N Y Acad Sci (1998) 1.22
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp Neurol (1999) 1.19
MPTP: current concepts and controversies. Clin Neuropharmacol (1986) 1.16
SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism. Hum Mol Genet (2005) 1.08
Hypothesis: the role of dopaminergic transporters in selective vulnerability of cells in Parkinson's disease. Ann Neurol (1998) 1.05
Estrogen as a neuroprotectant against MPTP-induced neurotoxicity in C57/B1 mice. Neurotoxicol Teratol (1997) 1.04
Reactive dopamine metabolites and neurotoxicity: implications for Parkinson's disease. Adv Exp Med Biol (1996) 1.02
Estrogen decreases corpus striatal neurotoxicity in response to 6-hydroxydopamine. Brain Res (1997) 0.97
Postmenopausal estrogen use and Parkinson's disease with and without dementia. Neurology (1998) 0.92
Estrogen alters MPTP-induced neurotoxicity in female mice: effects on striatal dopamine concentrations and release. J Neurochem (1996) 0.91
Parkinson's disease in China. Coordinational Group of Neuroepidemiology, PLA. Chin Med J (Engl) (1991) 0.90
The VMAT2 gene in mice and humans: amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins. FASEB J (2000) 0.90
Use of in vitro superfusion to assess the dynamics of striatal dopamine clearance: influence of estrogen. Brain Res (1999) 0.87
Loss of dopaminergic neurons in parkinsonism: possible role of reactive dopamine metabolites. J Neural Transm Suppl (1997) 0.86
Inhibition of striatal dopamine transporter activity by 17beta-estradiol. Eur J Pharmacol (1998) 0.85
Neuroprotective role of estrogen upon methamphetamine and related neurotoxins within the nigrostriatal dopaminergic system. Ann N Y Acad Sci (2000) 0.84
A molecular analysis of vesicular amine transport. Behav Brain Res (1996) 0.81
Aspects of tolerability of centrally acting antihypertensive drugs. J Cardiovasc Pharmacol (1996) 0.81
MPTP-induced parkinsonism. Prog Neurobiol (1990) 0.80
Influence of gonadal hormones on sexual differences in sensitivity to methamphetamine-induced neurotoxicity. J Neural Transm Park Dis Dement Sect (1994) 0.79
Structural organization of the human vesicular monoamine transporter type-2 gene and promoter analysis using the jelly fish green fluorescent protein as a reporter. Brain Res Mol Brain Res (1997) 0.79
The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43
Discerning the ancestry of European Americans in genetic association studies. PLoS Genet (2007) 7.81
A genomewide admixture map for Latino populations. Am J Hum Genet (2007) 4.71
Residential proximity to traffic and adverse birth outcomes in Los Angeles county, California, 1994-1996. Environ Health Perspect (2003) 3.66
Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. Nat Genet (2006) 3.54
Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California. Am J Epidemiol (2009) 3.02
Preterm birth: the interaction of traffic-related air pollution with economic hardship in Los Angeles neighborhoods. Am J Epidemiol (2005) 2.85
Association between local traffic-generated air pollution and preeclampsia and preterm delivery in the south coast air basin of California. Environ Health Perspect (2009) 2.45
Local variations in CO and particulate air pollution and adverse birth outcomes in Los Angeles County, California, USA. Environ Health Perspect (2005) 2.35
Genome-wide gene-environment study identifies glutamate receptor gene GRIN2A as a Parkinson's disease modifier gene via interaction with coffee. PLoS Genet (2011) 2.28
Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease. Neurology (2014) 2.24
BioImageXD: an open, general-purpose and high-throughput image-processing platform. Nat Methods (2012) 2.22
Meeting report: atmospheric pollution and human reproduction. Environ Health Perspect (2008) 2.19
Clinical characteristics in early Parkinson's disease in a central California population-based study. Mov Disord (2005) 2.19
Historical pesticide exposure in California using pesticide use reports and land-use surveys: an assessment of misclassification error and bias. Environ Health Perspect (2003) 2.03
Predicting traffic-related air pollution in Los Angeles using a distance decay regression selection strategy. Environ Res (2009) 1.96
Lack of replication of thirteen single-nucleotide polymorphisms implicated in Parkinson's disease: a large-scale international study. Lancet Neurol (2006) 1.92
An effective and efficient approach for manually improving geocoded data. Int J Health Geogr (2008) 1.91
The faroes statement: human health effects of developmental exposure to chemicals in our environment. Basic Clin Pharmacol Toxicol (2008) 1.91
Y-chromosome evidence for differing ancient demographic histories in the Americas. Am J Hum Genet (2003) 1.84
Well-water consumption and Parkinson's disease in rural California. Environ Health Perspect (2009) 1.81
Integrin-mediated cell adhesion to type I collagen fibrils. J Biol Chem (2004) 1.75
Parkinson's disease risk from ambient exposure to pesticides. Eur J Epidemiol (2011) 1.70
Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture. PLoS Genet (2013) 1.68
The outdoor air pollution and brain health workshop. Neurotoxicology (2012) 1.60
Neurodevelopmental disorders and prenatal residential proximity to agricultural pesticides: the CHARGE study. Environ Health Perspect (2014) 1.54
Inherited FANCD1/BRCA2 exon 7 splice mutations associated with acute myeloid leukaemia in Fanconi anaemia D1 are not found in sporadic childhood leukaemia. Br J Haematol (2005) 1.53
Nonsteroidal anti-inflammatory drugs may protect against Parkinson disease. Neurology (2007) 1.52
Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease. Proc Natl Acad Sci U S A (2012) 1.50
Project TENDR: Targeting Environmental Neuro-Developmental Risks The TENDR Consensus Statement. Environ Health Perspect (2016) 1.50
Ambient air pollution and autism in Los Angeles county, California. Environ Health Perspect (2012) 1.49
First trimester exposure to ambient air pollution, pregnancy complications and adverse birth outcomes in Allegheny County, PA. Matern Child Health J (2013) 1.44
Risk of Parkinson's disease after hospital contact for head injury: population based case-control study. BMJ (2008) 1.42
Comparing exposure assessment methods for traffic-related air pollution in an adverse pregnancy outcome study. Environ Res (2011) 1.42
Live cell multicolor imaging of lipid droplets with a new dye, LD540. Traffic (2009) 1.36
Neural tube defects and maternal residential proximity to agricultural pesticide applications. Am J Epidemiol (2006) 1.31
Assessing the influence of traffic-related air pollution on risk of term low birth weight on the basis of land-use-based regression models and measures of air toxics. Am J Epidemiol (2012) 1.30
Paraoxonase 1, agricultural organophosphate exposure, and Parkinson disease. Epidemiology (2010) 1.30
The epidemiology of neuroblastoma: a review. Paediatr Perinat Epidemiol (2009) 1.22
Traffic-related air toxics and preterm birth: a population-based case-control study in Los Angeles County, California. Environ Health (2011) 1.20
Particulate air pollution exposure and C-reactive protein during early pregnancy. Epidemiology (2011) 1.19
Traffic-related air toxics and term low birth weight in Los Angeles County, California. Environ Health Perspect (2011) 1.18
Traumatic brain injury, paraquat exposure, and their relationship to Parkinson disease. Neurology (2012) 1.17
Effects of subchronic and chronic exposure to ambient air pollutants on infant bronchiolitis. Am J Epidemiol (2006) 1.16
Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California. Am J Epidemiol (2011) 1.16
Estimated effects of solvents and mineral oils on cancer incidence and mortality in a cohort of aerospace workers. Am J Ind Med (2005) 1.15
Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease. Arch Neurol (2007) 1.14
Outdoor air pollution and uncontrolled asthma in the San Joaquin Valley, California. J Epidemiol Community Health (2010) 1.11
Statin use and the risk of Parkinson disease. Neurology (2008) 1.10
Epidemiology of rhabdoid tumors of early childhood. Pediatr Blood Cancer (2012) 1.10
Diabetes and the risk of developing Parkinson's disease in Denmark. Diabetes Care (2011) 1.09
A case-crossover study of wintertime ambient air pollution and infant bronchiolitis. Environ Health Perspect (2006) 1.08
Childhood cancer and traffic-related air pollution exposure in pregnancy and early life. Environ Health Perspect (2013) 1.07
Genetics of iron regulation and the possible role of iron in Parkinson's disease. Neurobiol Dis (2008) 1.07
Study of Use of Products and Exposure-Related Behaviors (SUPERB): study design, methods, and demographic characteristics of cohorts. Environ Health (2010) 1.06
Pancreatic cancer mortality and organochlorine pesticide exposure in California, 1989-1996. Am J Ind Med (2003) 1.04
Pre- and post-Columbian gene and cultural continuity: the case of the Gaucho from southern Brazil. Hum Hered (2007) 1.04
IARC monographs: 40 years of evaluating carcinogenic hazards to humans. Environ Health Perspect (2015) 1.03
Replication of GWAS associations for GAK and MAPT in Parkinson's disease. Ann Hum Genet (2010) 1.03
Traffic and outdoor air pollution levels near residences and poorly controlled asthma in adults. Ann Allergy Asthma Immunol (2007) 1.03
Perinatal characteristics and retinoblastoma. Cancer Causes Control (2012) 1.03
Heterogeneity of the genome ancestry of individuals classified as White in the state of Rio Grande do Sul, Brazil. Am J Hum Biol (2005) 1.03
Usage pattern of personal care products in California households. Food Chem Toxicol (2010) 1.02
α-Synuclein gene may interact with environmental factors in increasing risk of Parkinson's disease. Neuroepidemiology (2010) 1.02
Malignant melanoma, breast cancer and other cancers in patients with Parkinson's disease. Int J Cancer (2012) 1.02
Tetravalent single-chain avidin: from subunits to protein domains via circularly permuted avidins. Biochem J (2005) 1.01
Job exposure matrix (JEM)-derived estimates of lifetime occupational pesticide exposure and the risk of Parkinson's disease. Arch Environ Occup Health (2014) 1.00
In utero exposure to toxic air pollutants and risk of childhood autism. Epidemiology (2014) 1.00
Radiotherapy for oral cancer as a risk factor for second primary cancers. Cancer Lett (2005) 1.00
The "Latina epidemiologic paradox" revisited: the role of birthplace and acculturation in predicting infant low birth weight for Latinas in Los Angeles, CA. J Immigr Minor Health (2012) 1.00
Estimating Spatiotemporal Variability of Ambient Air Pollutant Concentrations with A Hierarchical Model. Atmos Environ (1994) (2013) 1.00
Nested case-control study of occupational physical activity and prostate cancer among workers using a job exposure matrix. Cancer Causes Control (2007) 0.99
Household organophosphorus pesticide use and Parkinson's disease. Int J Epidemiol (2013) 0.98
Research on the premotor symptoms of Parkinson's disease: clinical and etiological implications. Environ Health Perspect (2013) 0.98
Validation of hospital register-based diagnosis of Parkinson's disease. Dan Med J (2012) 0.98
Outdoor air pollution, family and neighborhood environment, and asthma in LA FANS children. Health Place (2008) 0.98
Prenatal exposure to traffic-related air pollution and risk of early childhood cancers. Am J Epidemiol (2013) 0.97
Outdoor work and risk for Parkinson's disease: a population-based case-control study. Occup Environ Med (2010) 0.95
Enhanced baculovirus-mediated transduction of human cancer cells by tumor-homing peptides. J Virol (2006) 0.95
Serum metabolomics of slow vs. rapid motor progression Parkinson's disease: a pilot study. PLoS One (2013) 0.95
Dissecting the genetic make-up of North-East Sardinia using a large set of haploid and autosomal markers. Eur J Hum Genet (2012) 0.94
Estimated effects of disinfection by-products on preterm birth in a population served by a single water utility. Environ Health Perspect (2006) 0.94
Are frequent asthma symptoms among low-income individuals related to heavy traffic near homes, vulnerabilities, or both? Ann Epidemiol (2008) 0.93
Indoor exposure to molds and allergic sensitization. Environ Health Perspect (2002) 0.93
Two synergistic activation mechanisms of alpha2beta1 integrin-mediated collagen binding. J Biol Chem (2007) 0.93
Use of generalized additive models and cokriging of spatial residuals to improve land-use regression estimates of nitrogen oxides in Southern California. Atmos Environ (1994) (2012) 0.93
Molecular mechanism of alpha2beta1 integrin interaction with human echovirus 1. EMBO J (2009) 0.92
Environmental public health tracking of childhood asthma using California health interview survey, traffic, and outdoor air pollution data. Environ Health Perspect (2008) 0.92
Demographic and evolutionary trajectories of the Guarani and Kaingang natives of Brazil. Am J Phys Anthropol (2007) 0.91
Evolutionary responses to a constructed niche: ancient Mesoamericans as a model of gene-culture coevolution. PLoS One (2012) 0.91
Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry (2014) 0.90
Association of DRD2 variants and Gilles de la Tourette syndrome in a family-based sample from a South American population isolate. Psychiatr Genet (2010) 0.89
Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset. Eur J Hum Genet (2009) 0.89
Validation of self-reported proximity to agricultural crops in a case-control study of neural tube defects. J Expo Sci Environ Epidemiol (2006) 0.89
Exposure to polycyclic aromatic hydrocarbons and missed abortion in early pregnancy in a Chinese population. Sci Total Environ (2010) 0.89
Longitudinal variability of time-location/activity patterns of population at different ages: a longitudinal study in California. Environ Health (2011) 0.89
An exploratory study of ambient air toxics exposure in pregnancy and the risk of neuroblastoma in offspring. Environ Res (2013) 0.88
Feasibility of using web surveys to collect time-activity data. J Expo Sci Environ Epidemiol (2011) 0.88
Functional paraoxonase 1 variants modify the risk of Parkinson's disease due to organophosphate exposure. Environ Int (2013) 0.88