Published in J Cell Sci on December 15, 2005
Tetrameric structure of centromeric nucleosomes in interphase Drosophila cells. PLoS Biol (2007) 3.25
Inactivation of a human kinetochore by specific targeting of chromatin modifiers. Dev Cell (2008) 2.50
The centromere: chromatin foundation for the kinetochore machinery. Dev Cell (2014) 2.00
Transgenerational propagation and quantitative maintenance of paternal centromeres depends on Cid/Cenp-A presence in Drosophila sperm. PLoS Biol (2012) 1.86
LINE retrotransposon RNA is an essential structural and functional epigenetic component of a core neocentromeric chromatin. PLoS Genet (2009) 1.73
Human centromeric chromatin is a dynamic chromosomal domain that can spread over noncentromeric DNA. Proc Natl Acad Sci U S A (2006) 1.72
Formation of functional centromeric chromatin is specified epigenetically in Candida albicans. Proc Natl Acad Sci U S A (2006) 1.29
Heterochromatin is required for normal distribution of Neurospora crassa CenH3. Mol Cell Biol (2011) 1.18
A minimal CENP-A core is required for nucleation and maintenance of a functional human centromere. EMBO J (2007) 1.08
Identification of a maize neocentromere in an oat-maize addition line. Cytogenet Genome Res (2009) 1.03
Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function. J Cell Sci (2012) 1.03
HACking the centromere chromatin code: insights from human artificial chromosomes. Chromosome Res (2012) 1.02
Strong epigenetic similarity between maize centromeric and pericentromeric regions at the level of small RNAs, DNA methylation and H3 chromatin modifications. Nucleic Acids Res (2011) 1.02
Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryos. Curr Biol (2011) 1.00
A cell-free system for functional centromere and kinetochore assembly. Nat Protoc (2012) 0.93
The past, present, and future of human centromere genomics. Genes (Basel) (2014) 0.92
De novo formed satellite DNA-based mammalian artificial chromosomes and their possible applications. Chromosome Res (2015) 0.88
Novel method to load multiple genes onto a mammalian artificial chromosome. PLoS One (2014) 0.88
The telomere bouquet regulates meiotic centromere assembly. Nat Cell Biol (2015) 0.85
An artificially constructed de novo human chromosome behaves almost identically to its natural counterpart during metaphase and anaphase in living cells. Mol Cell Biol (2006) 0.83
Regional centromeres in the yeast Candida lusitaniae lack pericentromeric heterochromatin. Proc Natl Acad Sci U S A (2015) 0.81
Neocentromeres come of age. PLoS Genet (2009) 0.78
Genetic and epigenetic regulation of centromeres: a look at HAC formation. Chromosome Res (2015) 0.77
ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol (2006) 5.46
Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (2003) 4.40
Autophagosomes form at ER-mitochondria contact sites. Nature (2013) 4.32
Meiotic proteins bqt1 and bqt2 tether telomeres to form the bouquet arrangement of chromosomes. Cell (2006) 3.67
GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast. Genes Dev (2003) 3.53
The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation. Curr Biol (2006) 3.37
Aneuploidy drives genomic instability in yeast. Science (2011) 3.22
Dynamic behavior of Nuf2-Hec1 complex that localizes to the centrosome and centromere and is essential for mitotic progression in vertebrate cells. J Cell Sci (2003) 2.78
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature (2009) 2.74
Selective elimination of messenger RNA prevents an incidence of untimely meiosis. Nature (2006) 2.64
Inactivation of a human kinetochore by specific targeting of chromatin modifiers. Dev Cell (2008) 2.50
Meiosis-specific noncoding RNA mediates robust pairing of homologous chromosomes in meiosis. Science (2012) 2.26
Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue-derived stromal cells. Arterioscler Thromb Vasc Biol (2005) 2.20
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
CENP-B controls centromere formation depending on the chromatin context. Cell (2007) 2.15
Dynamics of homologous chromosome pairing during meiotic prophase in fission yeast. Dev Cell (2004) 2.11
Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med (2010) 2.08
Clinical safety, tolerability, pharmacokinetics, and pharmacodynamics of the novel factor Xa inhibitor edoxaban in healthy volunteers. J Clin Pharmacol (2010) 1.98
Monopolar spindle attachment of sister chromatids is ensured by two distinct mechanisms at the first meiotic division in fission yeast. EMBO J (2003) 1.95
CENP-I is essential for centromere function in vertebrate cells. Dev Cell (2002) 1.94
Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway. Stem Cells (2007) 1.92
CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA. J Cell Biol (2002) 1.90
Heterochromatin integrity affects chromosome reorganization after centromere dysfunction. Science (2008) 1.88
The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein. Hum Mol Genet (2005) 1.88
Inhibitory effects of novel AP-1 decoy oligodeoxynucleotides on vascular smooth muscle cell proliferation in vitro and neointimal formation in vivo. Circ Res (2002) 1.87
Periostin as a novel factor responsible for ventricular dilation. Circulation (2004) 1.85
Adipose tissue-derived stromal cells as a novel option for regenerative cell therapy. J Atheroscler Thromb (2006) 1.78
Regulation of histone H3 lysine 56 acetylation in Schizosaccharomyces pombe. J Biol Chem (2007) 1.65
Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis. J Cell Biol (2005) 1.62
Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction. Hypertension (2006) 1.54
The DNA polymerase domain of pol(epsilon) is required for rapid, efficient, and highly accurate chromosomal DNA replication, telomere length maintenance, and normal cell senescence in Saccharomyces cerevisiae. J Biol Chem (2002) 1.54
Essential role for miR-196a in brown adipogenesis of white fat progenitor cells. PLoS Biol (2012) 1.53
Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly. J Cell Sci (2008) 1.53
Telomere-nuclear envelope dissociation promoted by Rap1 phosphorylation ensures faithful chromosome segregation. Curr Biol (2012) 1.53
Inhibitory effects of NFkappaB decoy oligodeoxynucleotides on neointimal hyperplasia in a rabbit vein graft model. J Mol Cell Cardiol (2006) 1.52
Effects of intra-aortic balloon pumping on graft flow in coronary surgery: an intraoperative transit-time flowmetric study. Ann Thorac Surg (2008) 1.50
Virtual breakdown of the nuclear envelope in fission yeast meiosis. Curr Biol (2010) 1.50
Cell cycle behavior of human HP1 subtypes: distinct molecular domains of HP1 are required for their centromeric localization during interphase and metaphase. J Cell Sci (2003) 1.49
Pharmacokinetics, biotransformation, and mass balance of edoxaban, a selective, direct factor Xa inhibitor, in humans. Drug Metab Dispos (2012) 1.48
Cellular stresses induce the nuclear accumulation of importin alpha and cause a conventional nuclear import block. J Cell Biol (2004) 1.46
Histone H3 lysine 56 acetylation: a new twist in the chromosome cycle. Cell Cycle (2006) 1.46
The constitutive centromere component CENP-50 is required for recovery from spindle damage. Mol Cell Biol (2005) 1.44
Dynamic interaction between BAF and emerin revealed by FRAP, FLIP, and FRET analyses in living HeLa cells. J Struct Biol (2004) 1.44
Linker histone variants control chromatin dynamics during early embryogenesis. Proc Natl Acad Sci U S A (2005) 1.43
Cadherin activity is required for activity-induced spine remodeling. J Cell Biol (2004) 1.43
The phosphorylated C-terminal domain of Xenopus Cut5 directly mediates ATR-dependent activation of Chk1. Genes Cells (2006) 1.42
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly. EMBO J (2012) 1.41
Emerin binding to Btf, a death-promoting transcriptional repressor, is disrupted by a missense mutation that causes Emery-Dreifuss muscular dystrophy. Eur J Biochem (2004) 1.41
Distinct roles of DNA polymerases delta and epsilon at the replication fork in Xenopus egg extracts. Genes Cells (2004) 1.41
Transit-time flow measurement cannot detect wrong anastomosis of an internal thoracic artery with the cardiac vein in coronary artery surgery. J Thorac Cardiovasc Surg (2004) 1.40
Another way to move chromosomes. Chromosoma (2007) 1.40
PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia. Proc Natl Acad Sci U S A (2011) 1.38
Impact of pre-implant lower urinary tract symptoms on postoperative urinary morbidity after permanent prostate brachytherapy. Int J Urol (2012) 1.38
Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities. J Cell Biol (2003) 1.36
MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation. Mol Cell (2010) 1.34
The 14-kDa dynein light chain-family protein Dlc1 is required for regular oscillatory nuclear movement and efficient recombination during meiotic prophase in fission yeast. Mol Biol Cell (2002) 1.32
Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice. Biochem Biophys Res Commun (2007) 1.32
Comparative roles of Twist-1 and Id1 in transcriptional regulation by BMP signaling. J Cell Sci (2007) 1.32
Rad51 siRNA delivered by HVJ envelope vector enhances the anti-cancer effect of cisplatin. J Gene Med (2005) 1.30
Human artificial chromosome with a conditional centromere for gene delivery and gene expression. DNA Res (2010) 1.29
Hexanucleotide motifs mediate recruitment of the RNA elimination machinery to silent meiotic genes. Open Biol (2012) 1.29
Dissociation of the Nuf2-Ndc80 complex releases centromeres from the spindle-pole body during meiotic prophase in fission yeast. Mol Biol Cell (2005) 1.27
Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology. Expert Opin Drug Deliv (2014) 1.26
Rapid generation of long synthetic tandem repeats and its application for analysis in human artificial chromosome formation. Nucleic Acids Res (2005) 1.26
Involvement of the Polycomb-group gene Ring1B in the specification of the anterior-posterior axis in mice. Development (2002) 1.26
Meiotic cohesins modulate chromosome compaction during meiotic prophase in fission yeast. J Cell Biol (2006) 1.25
Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance. Am J Pathol (2008) 1.23
Human gamma-satellite DNA maintains open chromatin structure and protects a transgene from epigenetic silencing. Genome Res (2009) 1.22
Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res (2007) 1.22
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A (2011) 1.21
Reconstitution of Saccharomyces cerevisiae prereplicative complex assembly in vitro. Genes Cells (2006) 1.21
Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Hypertension (2004) 1.19
In vivo evidence of angiogenesis induced by transcription factor Ets-1: Ets-1 is located upstream of angiogenesis cascade. Circulation (2004) 1.19
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier. Mol Biol Cell (2009) 1.19
Novel recombinant BCG and DNA-vaccination against tuberculosis in a cynomolgus monkey model. Vaccine (2005) 1.18
TRAIL and Noxa are selectively upregulated in prostate cancer cells downstream of the RIG-I/MAVS signaling pathway by nonreplicating Sendai virus particles. Clin Cancer Res (2012) 1.17
CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization. J Biol Chem (2003) 1.17
Sterile alpha motif containing domain 9 is involved in death signaling of malignant glioma treated with inactivated Sendai virus particle (HVJ-E) or type I interferon. Int J Cancer (2010) 1.16
Membrane proteins Bqt3 and -4 anchor telomeres to the nuclear envelope to ensure chromosomal bouquet formation. J Cell Biol (2009) 1.16
Selective inactivation of NF-kappaB in the liver using NF-kappaB decoy suppresses CCl4-induced liver injury and fibrosis. Am J Physiol Gastrointest Liver Physiol (2007) 1.15
Heat shock protein 72 enhances manganese superoxide dismutase activity during myocardial ischemia-reperfusion injury, associated with mitochondrial protection and apoptosis reduction. Circulation (2002) 1.15
Cytoplasmic dynein in fungi: insights from nuclear migration. J Cell Sci (2003) 1.15
Endothelial dysfunction in hyperglycemia as a trigger of atherosclerosis. Curr Diabetes Rev (2005) 1.14
Meiosis induced by inactivation of Pat1 kinase proceeds with aberrant nuclear positioning of centromeres in the fission yeast Schizosaccharomyces pombe. Genes Cells (2004) 1.13
Transfection of human hepatocyte growth factor gene ameliorates secondary lymphedema via promotion of lymphangiogenesis. Circulation (2006) 1.13
Novel prophylactic and therapeutic vaccine against tuberculosis. Vaccine (2009) 1.12
Axially chiral guanidine as highly active and enantioselective catalyst for electrophilic amination of unsymmetrically substituted 1,3-dicarbonyl compounds. J Am Chem Soc (2006) 1.11
Dnmt3a2 targets endogenous Dnmt3L to ES cell chromatin and induces regional DNA methylation. Genes Cells (2006) 1.11
Spectral imaging fluorescence microscopy. Genes Cells (2002) 1.11
Angiogenesis induced by endothelial nitric oxide synthase gene through vascular endothelial growth factor expression in a rat hindlimb ischemia model. Circulation (2003) 1.11
RNA content in the nucleolus alters p53 acetylation via MYBBP1A. EMBO J (2011) 1.11