Published in Tumour Biol on December 08, 2005
Heat shock proteins and heat shock factor 1 in carcinogenesis and tumor development: an update. Arch Toxicol (2012) 2.04
Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse. BMC Genomics (2009) 1.46
Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB. Breast Cancer Res (2011) 1.13
P-cadherin and beta-catenin are useful prognostic markers in breast cancer patients; beta-catenin interacts with heat shock protein Hsp27. Cell Stress Chaperones (2008) 1.01
A mouse model for triple-negative breast cancer tumor-initiating cells (TNBC-TICs) exhibits similar aggressive phenotype to the human disease. BMC Cancer (2012) 1.00
Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics. Transl Oncol (2011) 1.00
Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer. Radiother Oncol (2010) 0.90
Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN. Cell Stress Chaperones (2012) 0.88
Heat shock proteins in animal neoplasms and human tumours--a comparison. Cell Stress Chaperones (2008) 0.84
Peptide aptamers: tools to negatively or positively modulate HSPB1(27) function. Philos Trans R Soc Lond B Biol Sci (2013) 0.79
Absence of caveolin-1 alters heat shock protein expression in spontaneous mammary tumors driven by Her-2/neu expression. Histochem Cell Biol (2011) 0.79
Pathology-dependent effects linked to small heat shock proteins expression: an update. Scientifica (Cairo) (2012) 0.79
Involvement of small heat shock proteins, trehalose, and lipids in the thermal stress management in Schizosaccharomyces pombe. Cell Stress Chaperones (2015) 0.76
An in vitro assessment of liposomal topotecan simulating metronomic chemotherapy in combination with radiation in tumor-endothelial spheroids. Sci Rep (2015) 0.75
New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer (2002) 24.71
Annual report to the nation on the status of cancer, 1975-2000, featuring the uses of surveillance data for cancer prevention and control. J Natl Cancer Inst (2003) 7.06
HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med (2000) 6.20
Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem (2002) 6.16
CXCR4 regulates growth of both primary and metastatic breast cancer. Cancer Res (2004) 4.53
Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases. EMBO J (1998) 2.84
Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay. Cell (1998) 2.75
Silencing of CXCR4 blocks breast cancer metastasis. Cancer Res (2005) 2.59
Heat shock protein expression independently predicts clinical outcome in prostate cancer. Cancer Res (2000) 1.99
HSP70 peptidembearing and peptide-negative preparations act as chaperokines. Cell Stress Chaperones (2000) 1.36
Programmed cell death: many ways for cells to die decently. Ann Med (2002) 1.22
Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas. Br J Cancer (1999) 1.22
Surface expression of Hsp25 and Hsp72 differentially regulates tumor growth and metastasis. Tumour Biol (2005) 1.14
Specific blockade of the ERK pathway inhibits the invasiveness of tumor cells: down-regulation of matrix metalloproteinase-3/-9/-14 and CD44. Biochem Biophys Res Commun (2003) 1.13
Vanillin suppresses in vitro invasion and in vivo metastasis of mouse breast cancer cells. Eur J Pharm Sci (2005) 1.11
Both tissue inhibitors of metalloproteinases-1 (TIMP-1) and TIMP-2 activate Ras but through different pathways. Biochem Biophys Res Commun (2002) 1.06
Hsp27 as a prognostic and predictive factor in cancer. Prog Mol Subcell Biol (2002) 1.06
Heat shock proteins hsp27 and hsp70: lack of correlation with response to tamoxifen and clinical course of disease in estrogen receptor-positive metastatic breast cancer (a Southwest Oncology Group Study). Clin Cancer Res (1998) 1.05
The small heat shock protein hsp27 increases invasiveness but decreases motility of breast cancer cells. Invasion Metastasis (1997) 1.04
Progression of mouse mammary tumors: MCP-1-TNFalpha cross-regulatory pathway and clonal expression of promalignancy and antimalignancy factors. Int J Cancer (2003) 1.03
Hsp25 and Hsp70 in rodent tumors treated with doxorubicin and lovastatin. Cell Stress Chaperones (2003) 1.01
Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma. Melanoma Res (2003) 1.01
Effects of the flavonoid drug quercetin on the response of human prostate tumours to hyperthermia in vitro and in vivo. Int J Hyperthermia (2001) 0.96
Targeting HSP70-induced thermotolerance for design of thermal sensitizers. Int J Hyperthermia (2003) 0.90
HSP25 overexpression attenuates oxidative stress-induced apoptosis: roles of ERK1/2 signaling and manganese superoxide dismutase. Free Radic Biol Med (2004) 0.90
Hsp25 regulates the expression of p21(Waf1/Cip1/Sdi1) through multiple mechanisms. J Biochem (2002) 0.86
The small heat shock protein HSP27 is not an independent prognostic marker in axillary lymph node-negative breast cancer patients. Clin Cancer Res (1996) 0.86
Insurgent micrometastases: sleeper cells and harboring the enemy. J Surg Oncol (2005) 0.85
Comparison of tumor growth between hsp25- and hsp27-transfected murine L929 cells in nude mice. Int J Cancer (1997) 0.83
Heat shock and UV-B-induced DNA damage and mutagenesis in skin. Photochem Photobiol Sci (2003) 0.83
Induction of heat shock protein 27 by hydroxyurea and its relationship to experimental metastasis. Clin Exp Metastasis (1998) 0.83
Overexpression of Hsp27 affects the metastatic phenotype of human melanoma cells in vitro. Cell Stress Chaperones (2002) 0.83
Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues. Nat Chem Biol (2005) 3.46
Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells. Cancer Res (2005) 2.72
Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL. Nat Cell Biol (2008) 2.34
Induction of heat shock proteins by heregulin beta1 leads to protection from apoptosis and anchorage-independent growth. Oncogene (2005) 1.64
Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature. Proc Natl Acad Sci U S A (2013) 1.58
Stress-induced release of HSC70 from human tumors. Cell Immunol (2003) 1.36
Tumor-derived heat shock protein 70 peptide complexes are cross-presented by human dendritic cells. J Immunol (2002) 1.34
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol (2009) 1.31
Radiation-induced effects and the immune system in cancer. Front Oncol (2012) 1.27
Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72. J Immunol (2005) 1.26
Enhanced immunogenicity of heat shock protein 70 peptide complexes from dendritic cell-tumor fusion cells. J Immunol (2006) 1.16
Surface expression of Hsp25 and Hsp72 differentially regulates tumor growth and metastasis. Tumour Biol (2005) 1.14
Heat shock protein 90 stabilization of ErbB2 expression is disrupted by ATP depletion in myocytes. J Biol Chem (2005) 1.13
p73beta is regulated by protein kinase Cdelta catalytic fragment generated in the apoptotic response to DNA damage. J Biol Chem (2002) 1.12
Titin determines the Frank-Starling relation in early diastole. J Gen Physiol (2003) 1.10
Transcriptional activity and DNA binding of heat shock factor-1 involve phosphorylation on threonine 142 by CK2. Biochem Biophys Res Commun (2003) 1.03
Protein kinase A binds and activates heat shock factor 1. PLoS One (2010) 1.02
Serum heat shock protein 70 level as a biomarker of exceptional longevity. Mech Ageing Dev (2006) 1.01
Cardiovascular disease delay in centenarian offspring: role of heat shock proteins. Ann N Y Acad Sci (2004) 1.01
A mouse model for triple-negative breast cancer tumor-initiating cells (TNBC-TICs) exhibits similar aggressive phenotype to the human disease. BMC Cancer (2012) 1.00
Double-stranded RNA-dependent protein kinase (pkr) is essential for thermotolerance, accumulation of HSP70, and stabilization of ARE-containing HSP70 mRNA during stress. J Biol Chem (2002) 1.00
COPI coatomer complex proteins facilitate the translocation of anthrax lethal factor across vesicular membranes in vitro. Proc Natl Acad Sci U S A (2008) 0.98
hnRNP-K and Pur(alpha) act together to repress the transcriptional activity of the CD43 gene promoter. Blood (2002) 0.97
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol. Proc Natl Acad Sci U S A (2005) 0.97
Circulating tumor cells and serum tumor biomarkers in small cell lung cancer. Anticancer Res (2003) 0.92
Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes. Free Radic Biol Med (2010) 0.90
Major role of HSP70 as a paracrine inducer of cytokine production in human oxidized LDL treated macrophages. Atherosclerosis (2005) 0.90
c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage. J Biol Chem (2005) 0.90
Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer. Radiother Oncol (2010) 0.90
Severe scombroid fish poisoning: an underrecognized dermatologic emergency. J Am Acad Dermatol (2011) 0.89
New Chlamydia trachomatis L2 strains identified in a recent outbreak of lymphogranuloma venereum in Vienna, Austria. Sex Transm Dis (2008) 0.89
GRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro. Mol Microbiol (2011) 0.87
Chaperokine function of recombinant Hsp72 produced in insect cells using a baculovirus expression system is retained. J Biol Chem (2009) 0.86
Silencing Hsp25/Hsp27 gene expression augments proteasome activity and increases CD8+ T-cell-mediated tumor killing and memory responses. Cancer Prev Res (Phila) (2011) 0.86
IL-23 antagonizes UVR-induced immunosuppression through two mechanisms: reduction of UVR-induced DNA damage and inhibition of UVR-induced regulatory T cells. J Invest Dermatol (2009) 0.85
Phosphorylation of DNA topoisomerase I by the c-Abl tyrosine kinase confers camptothecin sensitivity. J Biol Chem (2004) 0.85
Adaptogens exert a stress-protective effect by modulation of expression of molecular chaperones. Phytomedicine (2009) 0.83
Sickle cell vaso-occlusive crisis induces the release of circulating serum heat shock protein-70. Am J Hematol (2005) 0.83
ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response. Biochem Biophys Res Commun (2012) 0.82
Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer. Mol Cancer Ther (2013) 0.81
Petiveria alliacea extracts uses multiple mechanisms to inhibit growth of human and mouse tumoral cells. BMC Complement Altern Med (2008) 0.81
Combined lentiviral and RNAi technologies for the delivery and permanent silencing of the hsp25 gene. Methods Mol Biol (2011) 0.81
Sézary syndrome and seronegative polyarthritis: treatment with extracorporeal photochemotherapy. J Am Acad Dermatol (2003) 0.80
Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells. Front Neurosci (2012) 0.80
Gallotannin-rich Caesalpinia spinosa fraction decreases the primary tumor and factors associated with poor prognosis in a murine breast cancer model. BMC Complement Altern Med (2013) 0.80
Stress-induced facilitation of host response to bacterial challenge in F344 rats is dependent on extracellular heat shock protein 72 and independent of alpha beta T cells. Stress (2012) 0.80
Mild cold-stress depresses immune responses: Implications for cancer models involving laboratory mice. Bioessays (2014) 0.80
Internalization of exogenous ADP-ribosylation factor 6 (Arf6) proteins into cells. Mol Cell Biochem (2011) 0.79
Combined hyperthermia and radiotherapy for the treatment of cancer. Cancers (Basel) (2011) 0.79
DIFFERENTIAL SERUM LEVEL OF SPECIFIC HAPTOGLOBIN ISOFORMS IN SMALL CELL LUNG CANCER. Curr Proteomics (2010) 0.79
Breast Cancer Risk Factors among Ugandan Women at a Tertiary Hospital: A Case-Control Study. Oncology (2016) 0.78
Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer. J Environ Pathol Toxicol Oncol (2004) 0.77
EGCG-meditated cyto- and genotoxicity in HaCat keratinocytes is impaired by cell-mediated clearance of auto-oxidation-derived H2O2: an algorithm for experimental setting correction. Toxicol Lett (2011) 0.77
Oral low-dose chemotherapy: successful treatment of an alveolar rhabdomyosarcoma during pregnancy. Pediatr Blood Cancer (2011) 0.77
SERPINE 1 Links Obesity and Diabetes: A Pilot Study. J Proteomics Bioinform (2010) 0.76
Positive or negative involvement of heat shock proteins in multiple sclerosis pathogenesis: an overview. J Neuropathol Exp Neurol (2014) 0.76
Quantitation of heat-shock proteins in clinical samples using mass spectrometry. Methods Mol Biol (2011) 0.75