Published in Free Radic Biol Med on August 12, 2010
New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate. Redox Biol (2014) 1.53
Antioxidant induces DNA damage, cell death and mutagenicity in human lung and skin normal cells. Sci Rep (2013) 0.91
Protection against oxidative DNA damage and stress in human prostate by glutathione S-transferase P1. Mol Carcinog (2012) 0.87
Study of Radioprotective Effect of Green Tea against Gamma Irradiation Using Micronucleus Assay on Binucleated Human Lymphocytes. Iran J Basic Med Sci (2012) 0.85
Protective effects of andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation. PLoS One (2013) 0.80
Cyclooxygenase-1 and prostacyclin production by endothelial cells in the presence of mild oxidative stress. PLoS One (2013) 0.79
The Antimicrobial Activity of (-)-Epigallocatehin-3-Gallate and Green Tea Extracts against Pseudomonas aeruginosa and Escherichia coli Isolated from Skin Wounds. Ann Dermatol (2014) 0.77
Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells. Ann Dermatol (2016) 0.75
EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice. Oxid Med Cell Longev (2017) 0.75
RNase P without RNA: identification and functional reconstitution of the human mitochondrial tRNA processing enzyme. Cell (2008) 3.15
Executioner caspase-3 and caspase-7 are functionally distinct proteases. Proc Natl Acad Sci U S A (2008) 2.74
Distinct Epidemiology and Clinical Consequence of Classic Versus Rare EGFR Mutations in Lung Adenocarcinoma. J Thorac Oncol (2015) 2.17
Chromosomal imbalances in primary and metastatic melanomas: over-representation of essential telomerase genes. Melanoma Res (2003) 1.83
DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies. PLoS Genet (2011) 1.65
Association of polymorphisms within androgen receptor, 5alpha-reductase, and PSA genes with prostate volume, clinical parameters, and endocrine status in elderly men. Prostate (2002) 1.56
Down-regulation of Sprouty2 in non-small cell lung cancer contributes to tumor malignancy via extracellular signal-regulated kinase pathway-dependent and -independent mechanisms. Mol Cancer Res (2007) 1.52
Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents. Toxicology (2004) 1.41
Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release. J Cell Mol Med (2012) 1.40
The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma. Oncogene (2002) 1.37
Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. Breast Cancer Res Treat (2007) 1.35
Green tea extract and (-)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities. FASEB J (2005) 1.35
Anticancer activity of metal complexes: involvement of redox processes. Antioxid Redox Signal (2011) 1.32
Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation. J Med Chem (2009) 1.32
Cell death and autophagy: cytokines, drugs, and nutritional factors. Toxicology (2008) 1.31
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo. J Allergy Clin Immunol (2009) 1.31
Serum amyloid A in uremic HDL promotes inflammation. J Am Soc Nephrol (2012) 1.27
KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients. Chem Biodivers (2008) 1.27
Published and perished? The influence of the searched protein database on the long-term storage of proteomics data. Mol Cell Proteomics (2011) 1.26
Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells. Biochem Biophys Res Commun (2009) 1.25
Resistance against novel anticancer metal compounds: differences and similarities. Drug Resist Updat (2008) 1.24
Gallic acid inhibits ribonucleotide reductase and cyclooxygenases in human HL-60 promyelocytic leukemia cells. Cancer Lett (2006) 1.24
Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition. Mol Cancer Ther (2008) 1.23
The sodium pump alpha1 sub-unit: a disease progression-related target for metastatic melanoma treatment. J Cell Mol Med (2009) 1.21
Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications. J Cancer Res Clin Oncol (2005) 1.18
Metabolism of the masked mycotoxin deoxynivalenol-3-glucoside in rats. Toxicol Lett (2012) 1.14
The major vault protein is responsive to and interferes with interferon-gamma-mediated STAT1 signals. J Cell Sci (2006) 1.12
The use of the alkaline comet assay with lymphocytes in human biomonitoring studies. Mutat Res (2004) 1.10
The activin axis in liver biology and disease. Mutat Res (2006) 1.10
Targeting of eEF1A with Amaryllidaceae isocarbostyrils as a strategy to combat melanomas. FASEB J (2010) 1.10
Expression and functional activity of the ABC-transporter proteins P-glycoprotein and multidrug-resistance protein 1 in human brain tumor cells and astrocytes. J Neurooncol (2002) 1.10
O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients. Neuro Oncol (2009) 1.09
Metal-based paullones as putative CDK inhibitors for antitumor chemotherapy. J Med Chem (2007) 1.09
Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents. J Med Chem (2009) 1.08
A novel technique to specifically analyze the secretome of cells and tissues. Electrophoresis (2005) 1.08
Seven novel and stable translocations associated with oncogenic gene expression in malignant melanoma. Neoplasia (2005) 1.08
Galectin 1 proangiogenic and promigratory effects in the Hs683 oligodendroglioma model are partly mediated through the control of BEX2 expression. Neoplasia (2009) 1.07
Prognostic significance of telomerase-associated parameters in glioblastoma: effect of patient age. Neuro Oncol (2013) 1.07
FGF18 in colorectal tumour cells: autocrine and paracrine effects. Carcinogenesis (2007) 1.06
The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells. Breast Cancer Res Treat (2010) 1.05
Effect of staining procedures on the results of micronucleus assays with exfoliated oral mucosa cells. Cancer Epidemiol Biomarkers Prev (2006) 1.05
Association of IGF1 and IGFBP3 polymorphisms with colorectal polyps and colorectal cancer risk. Cancer Causes Control (2009) 1.04
Up-regulation of the fibroblast growth factor 8 subfamily in human hepatocellular carcinoma for cell survival and neoangiogenesis. Hepatology (2011) 1.04
Differential effects of polymorphic alleles of FGF receptor 4 on colon cancer growth and metastasis. Cancer Res (2012) 1.03
Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy. J Biol Inorg Chem (2010) 1.03
Mechanisms underlying the anticancer activities of the angucycline landomycin E. Biochem Pharmacol (2007) 1.03
Cell characterization by proteome profiling applied to primary hepatocytes and hepatocyte cell lines Hep-G2 and Hep-3B. J Proteome Res (2010) 1.02
MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells. PLoS One (2012) 1.01
Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24). Biochem Pharmacol (2005) 1.01
A human model of epithelial to mesenchymal transition to monitor drug efficacy in hepatocellular carcinoma progression. Mol Cancer Ther (2011) 1.01
Local complement activation triggers neutrophil recruitment to the site of thrombus formation in acute myocardial infarction. Thromb Haemost (2009) 1.00
A polymorphism in the UDP-Glucuronosyltransferase 2B15 gene (D85Y) is not associated with prostate cancer risk. Cancer Epidemiol Biomarkers Prev (2002) 1.00
NORE1B is a putative tumor suppressor in hepatocarcinogenesis and may act via RASSF1A. Cancer Res (2009) 0.99
Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes. J Leukoc Biol (2009) 0.99
Deregulation of the activin/follistatin system in hepatocarcinogenesis. J Hepatol (2006) 0.98
Proteome maps of the main human peripheral blood constituents. J Proteome Res (2009) 0.97
The endonuclease Ankle1 requires its LEM and GIY-YIG motifs for DNA cleavage in vivo. J Cell Sci (2012) 0.97
Quantitative assessment of human serum high-abundance protein depletion. Electrophoresis (2008) 0.96
Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview. Br J Nutr (2008) 0.96
Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339. J Biol Inorg Chem (2010) 0.96
Multiple chromosomal abnormalities in human liver (pre)neoplasia. J Hepatol (2004) 0.96
Effects of Scrophularia extracts on tumor cell proliferation, death and intravasation through lymphoendothelial cell barriers. Int J Oncol (2012) 0.96
European Commission's proposal for a council recommendation on cancer screening. BMJ (2003) 0.96
Silencing the hsp25 gene eliminates migration capability of the highly metastatic murine 4T1 breast adenocarcinoma cell. Tumour Biol (2005) 0.95
Galectin-1 is implicated in the protein kinase C epsilon/vimentin-controlled trafficking of integrin-beta1 in glioblastoma cells. Brain Pathol (2009) 0.95
RNAi-mediated silencing of TEL/AML1 reveals a heat-shock protein- and survivin-dependent mechanism for survival. Blood (2006) 0.95
Promyelocytic HL60 cells express NADPH oxidase and are excellent targets in a rapid spectrophotometric microplate assay for extracellular superoxide. Toxicol Sci (2003) 0.95
Structural simplification of bioactive natural products with multicomponent synthesis. 3. Fused uracil-containing heterocycles as novel topoisomerase-targeting agents. J Med Chem (2011) 0.95
Extracellular matrix remodeling by bone marrow fibroblast-like cells correlates with disease progression in multiple myeloma. J Proteome Res (2013) 0.95
Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation. Oncotarget (2012) 0.94
Caspase-9 plays a marginal role in serum starvation-induced apoptosis. Exp Cell Res (2005) 0.93
Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna. PLoS Genet (2011) 0.93