Published in FASEB J on December 13, 2005
Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers. Br J Pharmacol (2009) 1.77
AON-mediated Exon Skipping Restores Ciliation in Fibroblasts Harboring the Common Leber Congenital Amaurosis CEP290 Mutation. Mol Ther Nucleic Acids (2012) 1.01
Zwitterionic phospholipids and sterols modulate antimicrobial peptide-induced membrane destabilization. Biophys J (2007) 0.99
Enhanced membrane disruption and antibiotic action against pathogenic bacteria by designed histidine-rich peptides at acidic pH. Antimicrob Agents Chemother (2006) 0.92
Effective endogenous gene silencing mediated by pH responsive peptides proceeds via multiple pathways. J Control Release (2011) 0.92
Control of pH responsive peptide self-association during endocytosis is required for effective gene transfer. Biochim Biophys Acta (2011) 0.85
Incorporation of 2,3-diaminopropionic acid into linear cationic amphipathic peptides produces pH-sensitive vectors. Chembiochem (2010) 0.83
Vectofusin-1, a new viral entry enhancer, strongly promotes lentiviral transduction of human hematopoietic stem cells. Mol Ther Nucleic Acids (2013) 0.83
Molecular Determinants of Vectofusin-1 and Its Derivatives for the Enhancement of Lentivirally Mediated Gene Transfer into Hematopoietic Stem/Progenitor Cells. J Biol Chem (2015) 0.83
Concurrent measures of fusion and transduction efficiency of primary CD34+ cells with human immunodeficiency virus 1-based lentiviral vectors reveal different effects of transduction enhancers. Hum Gene Ther Methods (2013) 0.82
Reversible liposome association induced by LAH4: a peptide with potent antimicrobial and nucleic acid transfection activities. Biophys J (2010) 0.80
pH- and ion-sensitive polymers for drug delivery. Expert Opin Drug Deliv (2013) 0.79
Buffering capacity and size of siRNA polyplexes influence cytokine levels. Mol Ther (2012) 0.78
Lipid interactions of LAH4, a peptide with antimicrobial and nucleic acid transfection activities. Eur Biophys J (2014) 0.76
Biophysical studies of the interactions between the phage varphiKZ gp144 lytic transglycosylase and model membranes. Eur Biophys J (2009) 0.76
Manipulating the pH response of 2,3-diaminopropionic acid rich peptides to mediate highly effective gene silencing with low-toxicity. J Control Release (2013) 0.75
pH-Dependent Membrane Interactions of the Histidine-Rich Cell-Penetrating Peptide LAH4-L1. Biophys J (2017) 0.75
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development. Hepatology (2010) 3.16
Rescue of dystrophic muscle through U7 snRNA-mediated exon skipping. Science (2004) 2.71
Multiexon skipping leading to an artificial DMD protein lacking amino acids from exons 45 through 55 could rescue up to 63% of patients with Duchenne muscular dystrophy. Hum Mutat (2007) 1.89
CUG-BP1/CELF1 requires UGU-rich sequences for high-affinity binding. Biochem J (2006) 1.73
High level cell-free expression and specific labeling of integral membrane proteins. Eur J Biochem (2004) 1.45
AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis. Hum Mol Genet (2008) 1.44
FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia. J Clin Invest (2004) 1.39
Incidence and natural history of mucopolysaccharidosis type III in France and comparison with United Kingdom and Greece. Am J Med Genet A (2011) 1.26
Investigations of polypeptide rotational diffusion in aligned membranes by 2H and 15N solid-state NMR spectroscopy. J Am Chem Soc (2004) 1.19
Intracerebral administration of adeno-associated viral vector serotype rh.10 carrying human SGSH and SUMF1 cDNAs in children with mucopolysaccharidosis type IIIA disease: results of a phase I/II trial. Hum Gene Ther (2014) 1.19
Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice. Proc Natl Acad Sci U S A (2007) 1.17
Efficient control of gene expression in the hematopoietic system using a single Tet-on inducible lentiviral vector. Mol Ther (2005) 1.17
Solution NMR structure of proteorhodopsin. Angew Chem Int Ed Engl (2011) 1.15
Histidine-rich amphipathic peptide antibiotics promote efficient delivery of DNA into mammalian cells. Proc Natl Acad Sci U S A (2003) 1.13
Phenotypic correction of alpha-sarcoglycan deficiency by intra-arterial injection of a muscle-specific serotype 1 rAAV vector. Mol Ther (2007) 1.13
Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs. Mol Cell Biol (2004) 1.09
Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases. Nucleic Acids Res (2012) 1.09
Design and evaluation of histidine-rich amphipathic peptides for siRNA delivery. Pharm Res (2010) 1.08
Membrane domain structures of three classes of histidine kinase receptors by cell-free expression and rapid NMR analysis. Proc Natl Acad Sci U S A (2010) 1.08
Cationic amphipathic histidine-rich peptides for gene delivery. Biochim Biophys Acta (2006) 1.07
Structural determinants of antimicrobial and antiplasmodial activity and selectivity in histidine-rich amphipathic cationic peptides. J Biol Chem (2008) 1.06
Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function. Proc Natl Acad Sci U S A (2005) 1.05
Evidence for a resident subset of cells with SP phenotype in the C2C12 myogenic line: a tool to explore muscle stem cell biology. Exp Cell Res (2004) 1.05
Transient immunomodulation allows repeated injections of AAV1 and correction of muscular dystrophy in multiple muscles. Mol Ther (2008) 1.04
15N photochemically induced dynamic nuclear polarization magic-angle spinning NMR analysis of the electron donor of photosystem II. Proc Natl Acad Sci U S A (2007) 1.02
Synthesis of linear polyethylenimine derivatives for DNA transfection. Bioconjug Chem (2003) 1.02
AON-mediated Exon Skipping Restores Ciliation in Fibroblasts Harboring the Common Leber Congenital Amaurosis CEP290 Mutation. Mol Ther Nucleic Acids (2012) 1.01
Structure and topology of the huntingtin 1-17 membrane anchor by a combined solution and solid-state NMR approach. Biophys J (2013) 1.01
Dynamic nuclear polarization-enhanced solid-state NMR of a 13C-labeled signal peptide bound to lipid-reconstituted Sec translocon. J Am Chem Soc (2011) 1.01
Genetic correction of canine dystrophic epidermolysis bullosa mediated by retroviral vectors. Hum Mol Genet (2003) 1.01
CD4+CD25+ regulatory T cells inhibit immune-mediated transgene rejection. Blood (2003) 1.01
SIN retroviral vectors expressing COL7A1 under human promoters for ex vivo gene therapy of recessive dystrophic epidermolysis bullosa. Mol Ther (2010) 1.01
Structure and dynamics of membrane-associated ICP47, a viral inhibitor of the MHC I antigen-processing machinery. J Biol Chem (2006) 1.00
Calcium ions promote formation of amyloid β-peptide (1-40) oligomers causally implicated in neuronal toxicity of Alzheimer's disease. PLoS One (2011) 1.00
Relative orientation between the beta-ionone ring and the polyene chain for the chromophore of rhodopsin in native membranes. Biochemistry (2002) 0.99
Use of a lentiviral flap vector for induction of CTL immunity against melanoma. Perspectives for immunotherapy. J Gene Med (2002) 0.99
Zwitterionic phospholipids and sterols modulate antimicrobial peptide-induced membrane destabilization. Biophys J (2007) 0.99
Efficient gene targeting mediated by a lentiviral vector-associated meganuclease. Nucleic Acids Res (2011) 0.98
Quantitative proteomic analysis of lentiviral vectors using 2-DE. Proteomics (2009) 0.98
Lipid-controlled peptide topology and interactions in bilayers: structural insights into the synergistic enhancement of the antimicrobial activities of PGLa and magainin 2. Biophys J (2011) 0.98
Congenital disorders of glycosylation type Ig is defined by a deficiency in dolichyl-P-mannose:Man7GlcNAc2-PP-dolichyl mannosyltransferase. J Biol Chem (2002) 0.98
The key residue for substrate transport (Glu14) in the EmrE dimer is asymmetric. J Biol Chem (2007) 0.97
Structure and alignment of the membrane-associated peptaibols ampullosporin A and alamethicin by oriented 15N and 31P solid-state NMR spectroscopy. Biophys J (2009) 0.97
RNA interference shows critical requirement for NF-kappa B p50 in the production of IL-12 by human dendritic cells. J Immunol (2003) 0.97
Solid-state NMR spectroscopy of oriented membrane polypeptides at 100 K with signal enhancement by dynamic nuclear polarization. J Am Chem Soc (2010) 0.97
Macromolecular crowding at membrane interfaces: adsorption and alignment of membrane peptides. J Mol Biol (2007) 0.96
Comparative analysis of the CD8(+) T cell repertoires of H-2 class I wild-type/HLA-A2.1 and H-2 class I knockout/HLA-A2.1 transgenic mice. Int Immunol (2002) 0.96
Intranasal gene delivery with a polyethylenimine-PEG conjugate. J Control Release (2002) 0.95
Deciphering membrane insertion of the diphtheria toxin T domain by specular neutron reflectometry and solid-state NMR spectroscopy. J Mol Biol (2009) 0.95
Long-term immune reconstitution in RAG-1-deficient mice treated by retroviral gene therapy: a balance between efficiency and toxicity. Blood (2005) 0.95
A partial down-regulation of WASP is sufficient to inhibit podosome formation in dendritic cells. Mol Ther (2005) 0.95
Magainin 2 in phospholipid bilayers: peptide orientation and lipid chain ordering studied by X-ray diffraction. Biochim Biophys Acta (2002) 0.95
Self-promoted cellular uptake of peptide/DNA transfection complexes. Biochemistry (2007) 0.94
Optimization of amino acid type-specific 13C and 15N labeling for the backbone assignment of membrane proteins by solution- and solid-state NMR with the UPLABEL algorithm. J Biomol NMR (2010) 0.93
Membrane interactions of the amphipathic amino terminus of huntingtin. Biochemistry (2013) 0.93
Optimising histidine rich peptides for efficient DNA delivery in the presence of serum. J Control Release (2006) 0.93
The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells. J Biol Chem (2003) 0.93
Enhanced membrane disruption and antibiotic action against pathogenic bacteria by designed histidine-rich peptides at acidic pH. Antimicrob Agents Chemother (2006) 0.92
Membrane order perturbation in the presence of antimicrobial peptides by (2)H solid-state NMR spectroscopy. Biochimie (2009) 0.92
In-cell solid-state NMR as a tool to study proteins in large complexes. Chembiochem (2012) 0.92
A spectroscopic study of the membrane interaction of the antimicrobial peptide Pleurocidin. Mol Membr Biol (2006) 0.91
Host-guest complexes as water-soluble high-performance DNP polarizing agents. J Am Chem Soc (2013) 0.91
Structure and membrane interactions of the antibiotic peptide dermadistinctin K by multidimensional solution and oriented 15N and 31P solid-state NMR spectroscopy. Biophys J (2009) 0.91
Detecting substrates bound to the secondary multidrug efflux pump EmrE by DNP-enhanced solid-state NMR. J Am Chem Soc (2013) 0.91
Crystal structure and functional mechanism of a human antimicrobial membrane channel. Proc Natl Acad Sci U S A (2013) 0.91
Gene therapy of RAG-2-/- mice: sustained correction of the immunodeficiency. Blood (2002) 0.90
Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation. Hum Mol Genet (2008) 0.90
Femoral intra-arterial injection: a tool to deliver and assess recombinant AAV constructs in rodents whole hind limb. J Gene Med (2005) 0.90
Localization of multidrug transporter substrates within model membranes. Biochemistry (2006) 0.90
Asymmetric ATP hydrolysis cycle of the heterodimeric multidrug ABC transport complex TmrAB from Thermus thermophilus. J Biol Chem (2010) 0.90
Tilt and rotational pitch angle of membrane-inserted polypeptides from combined 15N and 2H solid-state NMR spectroscopy. Biochemistry (2004) 0.89
Combined solid state and solution NMR studies of alpha,epsilon-15N labeled bovine rhodopsin. J Biomol NMR (2007) 0.89
Characterisation of Schiff base and chromophore in green proteorhodopsin by solid-state NMR. J Biomol NMR (2007) 0.89
How to prepare membrane proteins for solid-state NMR: A case study on the alpha-helical integral membrane protein diacylglycerol kinase from E. coli. Chembiochem (2005) 0.89
His75-Asp97 cluster in green proteorhodopsin. J Am Chem Soc (2011) 0.89
Voltage- and pH-dependent changes in vectoriality of photocurrents mediated by wild-type and mutant proteorhodopsins upon expression in Xenopus oocytes. J Mol Biol (2009) 0.89
Global transcriptional characterization of SP and MP cells from the myogenic C2C12 cell line: effect of FGF6. Physiol Genomics (2005) 0.89
Interactions involved in the realignment of membrane-associated helices. An investigation using oriented solid-state NMR and attenuated total reflection Fourier transform infrared spectroscopies. J Biol Chem (2006) 0.89
Solid-state NMR investigations of membrane-associated antimicrobial peptides. Methods Mol Biol (2010) 0.88
Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: application to interleukin 10 therapy in experimental arthritis. Hum Gene Ther (2002) 0.88
Membrane structure and conformational changes of the antibiotic heterodimeric peptide distinctin by solid-state NMR spectroscopy. Proc Natl Acad Sci U S A (2009) 0.88
Studying the stoichiometries of membrane proteins by mass spectrometry: microbial rhodopsins and a potassium ion channel. Phys Chem Chem Phys (2010) 0.88
Aggregation and membrane permeabilizing properties of designed histidine-containing cationic linear peptide antibiotics. J Pept Sci (2008) 0.88
Diverse genomic integration of a lentiviral vector developed for the treatment of Wiskott-Aldrich syndrome. J Gene Med (2009) 0.88
Characterization of the gene transfer process mediated by histidine-rich peptides. J Mol Med (Berl) (2006) 0.87
Probing the molecular dynamics of the ABC multidrug transporter LmrA by deuterium solid-state nuclear magnetic resonance. Biochemistry (2007) 0.87
Photo-CIDNP solid-state NMR on photosystems I and II:what makes P680 special? Photosynth Res (2005) 0.87
Cationic steroid antibiotics demonstrate DNA delivery properties. J Control Release (2005) 0.87
Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy. J Am Chem Soc (2012) 0.87