Published in Curr Opin Genet Dev on December 15, 2005
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Dev Cell (2010) 2.46
Phosphoproteome analysis of Drosophila melanogaster embryos. J Proteome Res (2008) 2.33
Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacol Rev (2011) 2.25
Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. Genes Dev (2006) 2.06
In vivo analysis of Yorkie phosphorylation sites. Oncogene (2009) 2.00
vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis. Development (2006) 1.79
Antagonistic regulation of apoptosis and differentiation by the Cut transcription factor represents a tumor-suppressing mechanism in Drosophila. PLoS Genet (2012) 1.49
Abnormalities in cell proliferation and apico-basal cell polarity are separable in Drosophila lgl mutant clones in the developing eye. Dev Biol (2007) 1.33
Drosophila melanogaster in the study of human neurodegeneration. CNS Neurol Disord Drug Targets (2010) 1.33
From bench to drug: human seizure modeling using Drosophila. Prog Neurobiol (2007) 1.24
Microfluidic chamber arrays for whole-organism behavior-based chemical screening. Lab Chip (2011) 1.23
Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Res (2007) 1.13
Whole-genome sequencing uncovers the genetic basis of chronic mountain sickness in Andean highlanders. Am J Hum Genet (2013) 1.06
Modeling tumor invasion and metastasis in Drosophila. Dis Model Mech (2011) 1.00
Yes-associated protein expression in head and neck squamous cell carcinoma nodal metastasis. PLoS One (2011) 0.99
Drosophila orthologue of WWOX, the chromosomal fragile site FRA16D tumour suppressor gene, functions in aerobic metabolism and regulates reactive oxygen species. Hum Mol Genet (2010) 0.98
A role for the epithelial microenvironment at tumor boundaries: evidence from Drosophila and human squamous cell carcinomas. Am J Pathol (2010) 0.95
Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila. PLoS Genet (2010) 0.93
Sumoylation is tumor-suppressive and confers proliferative quiescence to hematopoietic progenitors in Drosophila melanogaster larvae. Biol Open (2011) 0.91
Comparative study of tumorigenesis and tumor immunity in invertebrates and nonmammalian vertebrates. Dev Comp Immunol (2010) 0.90
YAP is a critical oncogene in human cholangiocarcinoma. Oncotarget (2015) 0.89
At the crossroads of polarity, proliferation and apoptosis: the use of Drosophila to unravel the multifaceted role of endocytosis in tumor suppression. Mol Oncol (2009) 0.87
Drosophila melanogaster as a model system for genetics of postnatal cardiac function. Drug Discov Today Dis Models (2008) 0.87
Intercellular cooperation and competition in brain cancers: lessons from Drosophila and human studies. Stem Cells Transl Med (2014) 0.86
How to innervate a simple gut: familiar themes and unique aspects in the formation of the insect enteric nervous system. Dev Dyn (2007) 0.84
The dark side of fly TNF: an ancient developmental proof reading mechanism turned into tumor promoter. Cell Cycle (2010) 0.84
Regulation of Yorkie activity in Drosophila imaginal discs by the Hedgehog receptor gene patched. Mech Dev (2012) 0.83
Evaluating Drosophila p53 as a model system for studying cancer mutations. J Biol Chem (2012) 0.82
The genetic basis of chronic mountain sickness. Physiology (Bethesda) (2014) 0.82
Asparagus cochinchinensis Extract Alleviates Metal Ion-Induced Gut Injury in Drosophila: An In Silico Analysis of Potential Active Constituents. Evid Based Complement Alternat Med (2016) 0.82
The Little Fly that Could: Wizardry and Artistry of Drosophila Genomics. Genes (Basel) (2014) 0.81
Functional interactions between the Moses corepressor and DHR78 nuclear receptor regulate growth in Drosophila. Genes Dev (2007) 0.79
FAK acts as a suppressor of RTK-MAP kinase signalling in Drosophila melanogaster epithelia and human cancer cells. PLoS Genet (2014) 0.79
Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila. PLoS One (2013) 0.78
The orthologous Tbx transcription factors Omb and TBX2 induce epithelial cell migration and extrusion in vivo without involvement of matrix metalloproteinases. Oncotarget (2014) 0.78
Orthologs of human disease associated genes and RNAi analysis of silencing insulin receptor gene in Bombyx mori. Int J Mol Sci (2014) 0.78
A Drosophila model for genetic analysis of influenza viral/host interactions. Genetics (2011) 0.78
Dampening the signals transduced through hedgehog via microRNA miR-7 facilitates notch-induced tumourigenesis. PLoS Biol (2013) 0.78
Genetic dissection of leukemia-associated IDH1 and IDH2 mutants and D-2-hydroxyglutarate in Drosophila. Blood (2014) 0.78
A protocol for genetic induction and visualization of benign and invasive tumors in cephalic complexes of Drosophila melanogaster. J Vis Exp (2013) 0.78
A transgenic Drosophila model for arsenic methylation suggests a metabolic rationale for differential dose-dependent toxicity endpoints. Toxicol Sci (2011) 0.77
Drosophila as a Potential Model for Ocular Tumors. Ocul Oncol Pathol (2015) 0.77
The legacy of Drosophila imaginal discs. Chromosoma (2016) 0.76
A gain-of-function germline mutation in Drosophila ras1 affects apoptosis and cell fate during development. PLoS One (2011) 0.75
A fragmented alignment method detects a phosphorylation site and a new BRC repeat in the Drosophila melanogaster BRCA2 protein, and a new HAT repeat in Utp6 from yeast. F1000Res (2013) 0.75
Magi Is Associated with the Par Complex and Functions Antagonistically with Bazooka to Regulate the Apical Polarity Complex. PLoS One (2016) 0.75
The interplay between obesity and cancer: a fly view. Dis Model Mech (2016) 0.75
Cross-species analysis of genetically engineered mouse models of MAPK-driven colorectal cancer identifies hallmarks of the human disease. Dis Model Mech (2014) 0.75
Loss of histone deacetylase HDAC1 induces cell death in Drosophila epithelial cells through JNK and Hippo signaling. Mech Dev (2016) 0.75
Loss of putzig Activity Results in Apoptosis during Wing Imaginal Development in Drosophila. PLoS One (2015) 0.75
Oncogenic Ras diverts a host TNF tumor suppressor activity into tumor promoter. Dev Cell (2010) 2.46
Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature (2012) 2.33
Csk-deficient boundary cells are eliminated from normal Drosophila epithelia by exclusion, migration, and apoptosis. Dev Cell (2006) 2.02
A high-sugar diet produces obesity and insulin resistance in wild-type Drosophila. Dis Model Mech (2011) 1.92
Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling. Cell (2013) 1.69
Systematic analysis of the transcriptional switch inducing migration of border cells. Dev Cell (2006) 1.63
A Drosophila p38 orthologue is required for environmental stress responses. EMBO Rep (2004) 1.28
Echinoid is essential for regulation of Egfr signaling and R8 formation during Drosophila eye development. Development (2003) 1.25
Patterning the fly eye: the role of apoptosis. Trends Genet (2003) 1.21
Drosophila C-terminal Src kinase negatively regulates organ growth and cell proliferation through inhibition of the Src, Jun N-terminal kinase, and STAT pathways. Mol Cell Biol (2004) 1.18
Differing Src signaling levels have distinct outcomes in Drosophila. Cancer Res (2007) 1.13
Dmp53 protects the Drosophila retina during a developmentally regulated DNA damage response. EMBO J (2003) 1.13
The Drosophila CD2AP/CIN85 orthologue Cindr regulates junctions and cytoskeleton dynamics during tissue patterning. J Cell Biol (2008) 1.11
Drosophila cancer models. Dev Dyn (2011) 1.10
Cellular behavior in the developing Drosophila pupal retina. Mech Dev (2007) 1.07
A Drosophila model of multiple endocrine neoplasia type 2. Genetics (2005) 1.03
Polychaetoid controls patterning by modulating adhesion in the Drosophila pupal retina. Dev Biol (2008) 0.98
Caspase signalling in the absence of apoptosis drives Jnk-dependent invasion. EMBO Rep (2013) 0.95
Preferential adhesion maintains separation of ommatidia in the Drosophila eye. Dev Biol (2010) 0.92
A quantitative method to analyze Drosophila pupal eye patterning. PLoS One (2009) 0.90
Bridging the gap between basic and applied biology: towards preclinical translation. Dis Model Mech (2013) 0.86
Chimaerin and Rac regulate cell number, adherens junctions, and ERK MAP kinase signaling in the Drosophila eye. Proc Natl Acad Sci U S A (2007) 0.85
Role for a Cindr-Arf6 axis in patterning emerging epithelia. Mol Biol Cell (2011) 0.84
Canonical wingless signaling regulates cone cell specification in the Drosophila retina. Dev Dyn (2010) 0.82
Computer simulation of cellular patterning within the Drosophila pupal eye. PLoS Comput Biol (2010) 0.82
A Drosophila functional evaluation of candidates from human genome-wide association studies of type 2 diabetes and related metabolic traits identifies tissue-specific roles for dHHEX. BMC Genomics (2013) 0.80
A Drosophila approach to thyroid cancer therapeutics. Drug Discov Today Technol (2013) 0.80
Interactions between Drosophila IgCAM adhesion receptors and cindr, the Cd2ap/Cin85 ortholog. Dev Dyn (2012) 0.77
Preface. Aspects of eye development: advances over the past twenty years. Curr Top Dev Biol (2010) 0.75