Gap junctions in skeletal development and function.

Inhibition of gap junction communication at ectopic Eph/ephrin boundaries underlies craniofrontonasal syndrome. PLoS Biol (2006) 2.43

Engineering anatomically shaped human bone grafts. Proc Natl Acad Sci U S A (2009) 2.37

Eph/ephrin signaling: networks. Genes Dev (2008) 2.13

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling. Mol Biol Cell (2011) 1.63

Cell-cell communication in the osteoblast/osteocyte lineage. Arch Biochem Biophys (2008) 1.52

Connexins: a myriad of functions extending beyond assembly of gap junction channels. Cell Commun Signal (2009) 1.49

Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress. Front Biosci (2007) 1.34

Osteocyte: the unrecognized side of bone tissue. Osteoporos Int (2010) 1.31

Pannexin 3 functions as an ER Ca(2+) channel, hemichannel, and gap junction to promote osteoblast differentiation. J Cell Biol (2011) 1.29

Connexin43 potentiates osteoblast responsiveness to fibroblast growth factor 2 via a protein kinase C-delta/Runx2-dependent mechanism. Mol Biol Cell (2009) 1.22

Connexin 43 is a potential prognostic biomarker for ewing sarcoma/primitive neuroectodermal tumor. Sarcoma (2011) 1.10

Gap junctions and hemichannels in signal transmission, function and development of bone. Biochim Biophys Acta (2011) 1.08

ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts. Am J Physiol Cell Physiol (2012) 1.05

Beyond gap junctions: Connexin43 and bone cell signaling. Bone (2012) 1.02

Interaction of connexin43 and protein kinase C-delta during FGF2 signaling. BMC Biochem (2010) 0.98

Genome-wide association study identifies Loci and candidate genes for body composition and meat quality traits in Beijing-You chickens. PLoS One (2013) 0.96

Premature osteoblast clustering by enamel matrix proteins induces osteoblast differentiation through up-regulation of connexin 43 and N-cadherin. PLoS One (2011) 0.95

Gap junctional regulation of signal transduction in bone cells. FEBS Lett (2014) 0.93

Gap junction intercellular communication: a review of a potential platform to modulate craniofacial tissue engineering. J Biomed Mater Res B Appl Biomater (2009) 0.93

Connexin 43 hemichannels and intracellular signaling in bone cells. Front Physiol (2014) 0.92

A novel autosomal recessive GJA1 missense mutation linked to Craniometaphyseal dysplasia. PLoS One (2013) 0.90

Human articular chondrocytes express multiple gap junction proteins: differential expression of connexins in normal and osteoarthritic cartilage. Am J Pathol (2013) 0.88

Connexin 43 channels protect osteocytes against oxidative stress-induced cell death. J Bone Miner Res (2013) 0.87

Induction of an osteocyte-like phenotype by fibroblast growth factor-2. Biochem Biophys Res Commun (2010) 0.87

A new method to investigate how mechanical loading of osteocytes controls osteoblasts. Front Endocrinol (Lausanne) (2014) 0.82

Connexin43 modulation of osteoblast/osteocyte apoptosis: a potential therapeutic target? J Bone Miner Res (2008) 0.82

Connexins and pannexins in the skeleton: gap junctions, hemichannels and more. Cell Mol Life Sci (2015) 0.81

Role of apoptosis in pathogenesis and treatment of bone-related diseases. J Orthop Surg Res (2015) 0.81

Cell communication and tissue engineering. Commun Integr Biol (2010) 0.81

Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture. BMC Musculoskelet Disord (2014) 0.81

Connexin 43 Is Necessary for Salivary Gland Branching Morphogenesis and FGF10-induced ERK1/2 Phosphorylation. J Biol Chem (2015) 0.81

Osteoinductivity of calcium phosphate mediated by connexin 43. Biomaterials (2013) 0.80

miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1. Front Genet (2015) 0.80

Coupled cell networks are target cells of inflammation, which can spread between different body organs and develop into systemic chronic inflammation. J Inflamm (Lond) (2015) 0.79

Cx43 and mechanotransduction in bone. Curr Osteoporos Rep (2015) 0.78

Effects of drug discontinuation after short-term daily alendronate administration on osteoblasts and osteocytes in mice. Histochem Cell Biol (2016) 0.78

Osteocytic connexin hemichannels suppress breast cancer growth and bone metastasis. Oncogene (2016) 0.77

Regulation of gap junction function and Connexin 43 expression by cytochrome P450 oxidoreductase (CYPOR). Biochem Biophys Res Commun (2011) 0.76

Cx25 contributes to leukemia cell communication and chemosensitivity. Oncotarget (2015) 0.76

Gap Junctions and Biophysical Regulation of Bone Cells. Clin Rev Bone Miner Metab (2010) 0.76

The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes. Oncotarget (2016) 0.75

Elevated Intracellular Ca(2+) Signals by Oxidative Stress Activate Connexin 43 Hemichannels in Osteocytes. Bone Res (2013) 0.75

Aged male rats regenerate cortical bone with reduced osteocyte density and reduced secretion of nitric oxide after mechanical stimulation. Calcif Tissue Int (2013) 0.75

Endothelin signaling regulates mineralization and posttranscriptionally regulates SOST in TMOb cells via miR 126-3p. Physiol Rep (2017) 0.75

Connexins and Pannexins in Bone and Skeletal Muscle. Curr Osteoporos Rep (2017) 0.75

Intravenous ibandronate injections in postmenopausal women with osteoporosis: one-year results from the dosing intravenous administration study. Arthritis Rheum (2006) 2.82

Opposite bone remodeling effects of teriparatide and alendronate in increasing bone mass. Arch Intern Med (2005) 2.60

Increased prevalence of celiac disease and need for routine screening among patients with osteoporosis. Arch Intern Med (2005) 2.52

Depression, antidepressants, and bone health in older adults: a systematic review. J Am Geriatr Soc (2014) 2.08

Low peak bone mass and attenuated anabolic response to parathyroid hormone in mice with an osteoblast-specific deletion of connexin43. J Cell Sci (2006) 2.06

Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation. J Cell Biochem (2005) 1.69

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling. Mol Biol Cell (2011) 1.63

The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans. Hum Mol Genet (2007) 1.61

Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1). J Bone Miner Res (2008) 1.51

Gap junctional communication modulates gene transcription by altering the recruitment of Sp1 and Sp3 to connexin-response elements in osteoblast promoters. J Biol Chem (2003) 1.50

Deletion of connexin43 in osteoblasts/osteocytes leads to impaired muscle formation in mice. J Bone Miner Res (2015) 1.50

One-year effects of vitamin D and calcium supplementation on chronic periodontitis. J Periodontol (2010) 1.49

Targeted expression of a dominant-negative N-cadherin in vivo delays peak bone mass and increases adipogenesis. J Cell Sci (2004) 1.49

Effects of dietary calcium compared with calcium supplements on estrogen metabolism and bone mineral density. Am J Clin Nutr (2007) 1.49

Bone turnover in bone biopsies of patients with low-energy cortical fractures receiving bisphosphonates: a case series. Calcif Tissue Int (2009) 1.41

Cross-sectional study of vitamin D and calcium supplementation effects on chronic periodontitis. J Periodontol (2009) 1.40

Gap junctions regulate extracellular signal-regulated kinase signaling to affect gene transcription. Mol Biol Cell (2004) 1.33

N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood (2012) 1.33

Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells. Blood (2012) 1.30

N-cadherin and cadherin 11 modulate postnatal bone growth and osteoblast differentiation by distinct mechanisms. J Cell Sci (2010) 1.26

Single nucleotide polymorphisms in the P2X7 gene are associated to fracture risk and to effect of estrogen treatment. Pharmacogenet Genomics (2007) 1.23

Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis. J Bone Miner Res (2011) 1.23

Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study. J Rheumatol (2008) 1.18

Intercellular calcium signaling occurs between human osteoblasts and osteoclasts and requires activation of osteoclast P2X7 receptors. J Biol Chem (2001) 1.15

Bone loss after temporarily induced muscle paralysis by Botox is not fully recovered after 12 weeks. Ann N Y Acad Sci (2007) 1.09

Cell-cell adhesion and signaling through cadherins: connecting bone cells in their microenvironment. J Bone Miner Res (2006) 1.08

Safety considerations with bisphosphonates for the treatment of osteoporosis. Drug Saf (2007) 1.08

Accentuated ovariectomy-induced bone loss and altered osteogenesis in heterozygous N-cadherin null mice. J Bone Miner Res (2006) 1.05

Tibial loading increases osteogenic gene expression and cortical bone volume in mature and middle-aged mice. PLoS One (2012) 1.05

Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors. Blood (2012) 1.05

Activation of L-type calcium channels is required for gap junction-mediated intercellular calcium signaling in osteoblastic cells. J Biol Chem (2002) 1.04

Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient mice. PLoS One (2012) 1.03

Maintaining the trust of physicians and the public in the medical literature: report of a task force on scientific publishing of clinical trials. J Bone Miner Res (2007) 1.03

Cell-cell interactions in regulating osteogenesis and osteoblast function. Birth Defects Res C Embryo Today (2005) 1.02

Cell-to-cell interactions in bone. Biochem Biophys Res Commun (2005) 1.02

Development of mice with osteoblast-specific connexin43 gene deletion. Cell Commun Adhes (2003) 1.00

Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in mice. PLoS One (2012) 0.98

Heterogeneous nuclear ribonucleoprotein K represses transcription from a cytosine/thymidine-rich element in the osteocalcin promoter. Biochem J (2005) 0.97

Bisphosphonates improve trabecular bone mass and normalize cortical thickness in ovariectomized, osteoblast connexin43 deficient mice. Bone (2012) 0.96

Microfibril-associated glycoprotein-1, an extracellular matrix regulator of bone remodeling. J Biol Chem (2010) 0.94

Genomic approaches to identifying transcriptional regulators of osteoblast differentiation. Genome Biol (2003) 0.93

Patient satisfaction in postmenopausal women treated with a weekly bisphosphonate transitioned to once-monthly ibandronate. J Womens Health (Larchmt) (2009) 0.91

Molecular mechanisms of osteoblast/osteocyte regulation by connexin43. Calcif Tissue Int (2013) 0.91

Role of connexin43 in osteoblast response to physical load. Ann N Y Acad Sci (2006) 0.90

Dominant negative N-cadherin inhibits osteoclast differentiation by interfering with beta-catenin regulation of RANKL, independent of cell-cell adhesion. J Bone Miner Res (2005) 0.88

Genetic variation in the serotonin transporter and HTR1B receptor predicts reduced bone formation during serotonin reuptake inhibitor treatment in older adults. World J Biol Psychiatry (2013) 0.87

Relationships between clinical attachment level and spine and hip bone mineral density: data from healthy postmenopausal women. J Periodontol (2002) 0.85

Weightlessness and skeleton homeostasis. Hormones (Athens) (2006) 0.84

Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype. J Cell Sci (2013) 0.83

A new concept for bisphosphonate therapy: a rationale for the development of monthly oral dosing of ibandronate. Osteoporos Int (2005) 0.82

Cadherin-mediated cell-cell adhesion and signaling in the skeleton. Calcif Tissue Int (2013) 0.82

Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin. J Cell Sci (2013) 0.81

The oxidative metabolism of estrogen modulates response to ERT/HRT in postmenopausal women. Bone (2004) 0.80

N-cadherin restrains PTH activation of Lrp6/β-catenin signaling and osteoanabolic action. J Bone Miner Res (2015) 0.80

Cell-cell signaling: broadening our view of the basic multicellular unit. Calcif Tissue Int (2013) 0.79

The pattern of alveolar crest height change in healthy postmenopausal women after 3 years of hormone/estrogen replacement therapy. J Periodontol (2002) 0.79

Risedronate increases osteoblastic differentiation and function through connexin43. Biochem Biophys Res Commun (2013) 0.79

The pro-osteogenic action of beta-catenin requires interaction with BMP signaling, but not Tcf/Lef transcriptional activity. J Cell Biochem (2008) 0.79

Estrogen and/or calcium plus vitamin D increase mandibular bone mass. J Periodontol (2004) 0.79

A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats. J Bone Miner Res (2005) 0.78

Low-magnitude whole-body vibration does not enhance the anabolic skeletal effects of intermittent PTH in adult mice. J Orthop Res (2010) 0.78

Casting new light on the sunshine vitamin. Calcif Tissue Int (2013) 0.75