Published in Trends Biochem Sci on December 20, 2005
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Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin. J Biol Chem (2008) 0.96
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Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration. PLoS Genet (2010) 0.92
Class II formin targeting to the cell cortex by binding PI(3,5)P(2) is essential for polarized growth. J Cell Biol (2012) 0.92
FIG4, Charcot-Marie-Tooth disease, and hypopigmentation: a role for phosphoinositides in melanosome biogenesis? Pigment Cell Melanoma Res (2008) 0.91
A protein complex that regulates PtdIns(3,5)P2 levels. EMBO J (2009) 0.90
Lysosomal adaptation: how the lysosome responds to external cues. Cold Spring Harb Perspect Biol (2014) 0.90
Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways. J Biol Chem (2012) 0.89
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The nucleophosmin-anaplastic lymphoma kinase oncogene interacts, activates, and uses the kinase PIKfyve to increase invasiveness. J Biol Chem (2011) 0.83
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New insights into the functions of PtdIns(3,5)P2 in the pathogenisis of neurodegenerative disorders. Neural Regen Res (2016) 0.75
RAB-10 Promotes EHBP-1 Bridging of Filamentous Actin and Tubular Recycling Endosomes. PLoS Genet (2016) 0.75
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An intramolecular interaction within the lipid kinase Fab1 regulates cellular phosphatidylinositol 3,5-bisphosphate lipid levels. Mol Biol Cell (2017) 0.75
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Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors. EMBO J (2004) 2.73
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PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49. Mol Biol Cell (2004) 1.57
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Slm1 and slm2 are novel substrates of the calcineurin phosphatase required for heat stress-induced endocytosis of the yeast uracil permease. Mol Cell Biol (2006) 1.51
Palmitoylation of the EGFR ligand Spitz by Rasp increases Spitz activity by restricting its diffusion. Dev Cell (2006) 1.47
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Argos inhibits epidermal growth factor receptor signalling by ligand sequestration. Nature (2004) 1.30
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Essential role for Rac in heregulin beta1 mitogenic signaling: a mechanism that involves epidermal growth factor receptor and is independent of ErbB4. Mol Cell Biol (2006) 1.19
A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein. Mol Cell Proteomics (2006) 1.17
Activation of the G(i) heterotrimeric G protein by ANCA IgG F(ab')2 fragments is necessary but not sufficient to stimulate the recruitment of those downstream mediators used by intact ANCA IgG. J Am Soc Nephrol (2003) 1.14
The p21-activated protein kinase-related kinase Cla4 is a coincidence detector of signaling by Cdc42 and phosphatidylinositol 4-phosphate. J Biol Chem (2004) 1.14
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A novel method of differential gene expression analysis using multiple cDNA libraries applied to the identification of tumour endothelial genes. BMC Genomics (2008) 1.10
Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. J Cell Sci (2006) 1.10
Structural basis for EGFR ligand sequestration by Argos. Nature (2008) 1.08
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Computational analysis of EGFR inhibition by Argos. Dev Biol (2005) 1.01
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Membrane activity of the phospholipase C-delta1 pleckstrin homology (PH) domain. Biochem J (2005) 0.98
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Erlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domain. Biochem J (2012) 0.95
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SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase. J Biol Chem (2004) 0.94
Mutations in or near the transmembrane domain alter PMEL amyloid formation from functional to pathogenic. PLoS Genet (2011) 0.90
A protein complex that regulates PtdIns(3,5)P2 levels. EMBO J (2009) 0.90
Characterization of phosphatidylinositol phosphate kinases from the moss Physcomitrella patens: PpPIPK1 and PpPIPK2. Plant Cell Physiol (2009) 0.87
Hypo-osmotic stress activates Plc1p-dependent phosphatidylinositol 4,5-bisphosphate hydrolysis and inositol Hexakisphosphate accumulation in yeast. J Biol Chem (2003) 0.87
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Functionally defining the endothelial transcriptome, from Robo4 to ECSCR. Biochem Soc Trans (2009) 0.84
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