Published in Front Biosci on May 01, 2006
Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing. Nat Genet (2008) 43.63
Architectures of somatic genomic rearrangement in human cancer amplicons at sequence-level resolution. Genome Res (2007) 6.91
A dynamic model for replication protein A (RPA) function in DNA processing pathways. Nucleic Acids Res (2006) 4.49
Base excision repair of oxidative DNA damage and association with cancer and aging. Carcinogenesis (2008) 2.42
Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells. PLoS Genet (2010) 2.14
Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability. Biochem J (2006) 1.99
Molecular population genetics and evolution of Drosophila meiosis genes. Genetics (2008) 1.41
Adeno-associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo. Hepatology (2010) 1.41
Biochemical characterization of metnase's endonuclease activity and its role in NHEJ repair. Biochemistry (2011) 1.10
Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants. Proc Natl Acad Sci U S A (2006) 1.06
Chromatin dynamics during repair of chromosomal DNA double-strand breaks. Epigenomics (2009) 1.05
DNA damage response. Cold Spring Harb Perspect Biol (2011) 1.03
Integration site selection by retroviral vectors: molecular mechanism and clinical consequences. Hum Gene Ther (2008) 1.01
Mutations to Ku reveal differences in human somatic cell lines. DNA Repair (Amst) (2008) 1.01
Capture of linear fragments at a double-strand break in yeast. Nucleic Acids Res (2007) 1.00
Atrx deficiency induces telomere dysfunction, endocrine defects, and reduced life span. J Clin Invest (2013) 0.98
AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Mol Immunol (2008) 0.96
Different fates of oocytes with DNA double-strand breaks in vitro and in vivo. Cell Cycle (2014) 0.96
Repair of gaps opposite lesions by homologous recombination in mammalian cells. Nucleic Acids Res (2009) 0.95
Escherichia coli genes and pathways involved in surviving extreme exposure to ionizing radiation. J Bacteriol (2014) 0.93
HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier? J Exp Clin Cancer Res (2008) 0.92
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer. Nat Commun (2014) 0.88
CREB-binding protein regulates Ku70 acetylation in response to ionization radiation in neuroblastoma. Mol Cancer Res (2012) 0.87
DNA bridging of yeast chromosomes VIII leads to near-reciprocal translocation and loss of heterozygosity with minor cellular defects. Chromosoma (2008) 0.87
Parkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress. Int J Mol Sci (2013) 0.86
Deregulation of DNA double-strand break repair in multiple myeloma: implications for genome stability. PLoS One (2015) 0.82
Rad54 oligomers translocate and cross-bridge double-stranded DNA to stimulate synapsis. J Mol Biol (2007) 0.82
Induced pluripotent stem cells are sensitive to DNA damage. Genomics Proteomics Bioinformatics (2013) 0.82
Viral hybrid vectors for somatic integration - are they the better solution? Viruses (2009) 0.81
Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection. J Virol (2011) 0.81
I-SceI-mediated double-strand DNA breaks stimulate efficient gene targeting in the industrial fungus Trichoderma reesei. Appl Microbiol Biotechnol (2015) 0.80
Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer. Clin Transl Med (2016) 0.79
Analysis of chromatin remodeling during formation of a DNA double-strand break at the yeast mating type locus. Methods (2009) 0.78
DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast. DNA Repair (Amst) (2013) 0.77
Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells. Nat Commun (2016) 0.76
Regulation of active genome integrity and expression by Rad26p. Nucleus (2014) 0.75
Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells. J Med Genet (2014) 0.75
Different contributions of the indirect effects of gamma-rays on the cytotoxicity in M10 and XRCC4 transfected M10 cells. Radiat Environ Biophys (2007) 0.75
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell (2008) 4.26
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature (2002) 3.48
Linkage between Werner syndrome protein and the Mre11 complex via Nbs1. J Biol Chem (2004) 1.36
Structural and functional analysis of Mre11-3. Nucleic Acids Res (2004) 1.28
Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway. J Biol Chem (2011) 1.21
Structure-based design of supercharged, highly thermoresistant antibodies. Chem Biol (2012) 1.19
Differential arrangements of conserved building blocks among homologs of the Rad50/Mre11 DNA repair protein complex. J Mol Biol (2004) 1.09
MlaA, a hexameric ATPase linked to the Mre11 complex in archaeal genomes. EMBO Rep (2004) 1.03
Llama-derived single domain antibodies specific for Abrus agglutinin. Toxins (Basel) (2011) 0.96
Radiosensitization of head/neck squamous cell carcinoma by adenovirus-mediated expression of the Nbs1 protein. Int J Radiat Oncol Biol Phys (2007) 0.95
Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer. Otolaryngol Head Neck Surg (2004) 0.88
Dimerization of the Rad50 protein is independent of the conserved hook domain. Mutagenesis (2007) 0.84
Defective p53 response and apoptosis associated with an ataxia-telangiectasia-like phenotype. Cancer Res (2006) 0.78
Multicenter Experience Using a New Prototype Transnasal Transesophageal Echocardiography Probe. Echocardiography (1999) 0.77
Inhibition of the 5' to 3' exonuclease activity of hEXO1 by 8-oxoguanine. Environ Mol Mutagen (2008) 0.77
Transnasal Transesophageal Stress Echocardiography. Echocardiography (1998) 0.76