Published in PLoS Pathog on December 30, 2005
A CD74-dependent MHC class I endolysosomal cross-presentation pathway. Nat Immunol (2012) 1.23
Maturation pathways of dendritic cells determine TAP1 and TAP2 levels and cross-presenting function. J Immunother (2009) 1.01
Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses. PLoS One (2008) 0.95
MHC-restricted cytotoxic T cells: studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv Immunol (1979) 15.58
The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides. Cell (1986) 14.96
Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity (1997) 5.44
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature (2003) 4.18
Phagosomes are competent organelles for antigen cross-presentation. Nature (2003) 3.97
Impaired assembly and transport of HLA-A and -B antigens in a mutant TxB cell hybrid. EMBO J (1986) 3.78
Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses. Proc Natl Acad Sci U S A (2003) 3.18
Induction of CD8+ cytotoxic T cells by immunization with purified HIV-1 envelope protein in ISCOMs. Nature (1990) 3.15
Restored expression of major histocompatibility class I molecules by gene transfer of a putative peptide transporter. Nature (1991) 3.12
MHC class II region encoding proteins related to the multidrug resistance family of transmembrane transporters. Nature (1991) 2.94
Both carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model. J Virol (2001) 2.73
The major substrates for TAP in vivo are derived from newly synthesized proteins. Nature (2000) 2.70
Second proteasome-related gene in the human MHC class II region. Nature (1991) 2.29
Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nat Immunol (2003) 2.27
Advances in vaccine adjuvants. Nat Biotechnol (1999) 2.18
DNA vaccination with vaccinia virus L1R and A33R genes protects mice against a lethal poxvirus challenge. Virology (2000) 2.16
Evidence that transporters associated with antigen processing translocate a major histocompatibility complex class I-binding peptide into the endoplasmic reticulum in an ATP-dependent manner. Proc Natl Acad Sci U S A (1993) 2.16
Early phagosomes in dendritic cells form a cellular compartment sufficient for cross presentation of exogenous antigens. Proc Natl Acad Sci U S A (2003) 2.09
Vaccinia virus immune evasion. Immunol Rev (1997) 2.03
MHC class I/beta 2-microglobulin complexes associate with TAP transporters before peptide binding. Nature (1994) 1.93
Selectivity of MHC-encoded peptide transporters from human, mouse and rat. Nature (1994) 1.88
Peptide translocation by variants of the transporter associated with antigen processing. Science (1993) 1.71
Characterization of the major histocompatibility complex class I deficiencies in B16 melanoma cells. Cancer Res (2001) 1.66
Interaction of MHC class I molecules with the transporter associated with antigen processing. Science (1994) 1.65
The peptide-binding motif for the human transporter associated with antigen processing. J Exp Med (1995) 1.56
Treatment of lethal vaccinia virus respiratory infections in mice with cidofovir. Antivir Chem Chemother (2001) 1.43
Vaccinia virus interleukin-18-binding protein promotes virulence by reducing gamma interferon production and natural killer and T-cell activity. J Virol (2003) 1.34
TAP expression provides a general method for improving the recognition of malignant cells in vivo. Nat Biotechnol (2000) 1.26
Multiple antigen-specific processing pathways for activating naive CD8+ T cells in vivo. J Immunol (2001) 1.25
Assembly, intracellular localization, and nucleotide binding properties of the human peptide transporters TAP1 and TAP2 expressed by recombinant vaccinia viruses. J Biol Chem (1995) 1.21
Requirements for peptide binding to the human transporter associated with antigen processing revealed by peptide scans and complex peptide libraries. J Biol Chem (1995) 1.11
Defective presentation of MHC class I-restricted cytotoxic T-cell epitopes in Burkitt's lymphoma cells. Int J Cancer (1996) 1.02
A point mutation in the human transporter associated with antigen processing (TAP2) alters the peptide transport specificity. Eur J Immunol (1996) 0.95
Genetically engineered vaccines: an overview. Plasmid (1998) 0.92
In vitro priming of cytotoxic T lymphocytes against poorly immunogenic epitopes by engineered antigen-presenting cells. Eur J Immunol (1994) 0.91
Peptide selection by MHC-encoded TAP transporters. Curr Opin Immunol (1994) 0.89
In vitro induction of naive cytotoxic T lymphocytes with complexes of peptide and recombinant MHC class I molecules coated onto beads: role of TCR/ligand density. Eur J Immunol (1998) 0.87
Alternative processing for MHC class I presentation by immature and CpG-activated dendritic cells. Eur J Immunol (2004) 0.80
Endolysosomal processing of exogenous antigen into major histocompatibility complex class I-binding peptides. Scand J Immunol (2004) 0.80
Viral vaccines: achievements and challenges. Acta Virol (1989) 0.76
Control of dendritic cell cross-presentation by the major histocompatibility complex class I cytoplasmic domain. Nat Immunol (2003) 2.27
Immune parameters correlate with protection against ebola virus infection in rodents and nonhuman primates. Sci Transl Med (2012) 1.83
The Ca(v)1.4 calcium channel is a critical regulator of T cell receptor signaling and naive T cell homeostasis. Immunity (2011) 1.73
Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease model. Microcirculation (2003) 1.69
A systematic review of health care efficiency measures. Health Serv Res (2009) 1.52
Blood-brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE. J Neuroimmunol (2010) 1.48
Assessment of a vesicular stomatitis virus-based vaccine by use of the mouse model of Ebola virus hemorrhagic fever. J Infect Dis (2007) 1.37
Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. PLoS One (2011) 1.27
Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease. FASEB J (2006) 1.25
Epigenetic enhancement of antigen processing and presentation promotes immune recognition of tumors. Cancer Res (2008) 1.24
Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Mol Ther Nucleic Acids (2012) 1.24
A CD74-dependent MHC class I endolysosomal cross-presentation pathway. Nat Immunol (2012) 1.23
Identification and functional characterization of voltage-dependent calcium channels in T lymphocytes. J Biol Chem (2003) 1.16
NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP). CNS Drug Rev (2005) 1.16
The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARgamma in rat activated hepatic stellate cell in vitro. Lab Invest (2007) 1.15
A new mixed-backbone oligonucleotide against glucosylceramide synthase sensitizes multidrug-resistant tumors to apoptosis. PLoS One (2009) 1.11
High transcytosis of melanotransferrin (P97) across the blood-brain barrier. J Neurochem (2002) 1.07
Roles of CRAC and Cav-like channels in T cells: more than one gatekeeper? Trends Pharmacol Sci (2006) 1.05
Molecular characterization of L-type calcium channel splice variants expressed in human T lymphocytes. Mol Immunol (2005) 1.04
MHC class I endosomal and lysosomal trafficking coincides with exogenous antigen loading in dendritic cells. PLoS One (2008) 1.04
Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation. Trends Immunol (2005) 1.01
Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. J Biol Chem (2002) 0.98
Restoration of the expression of transporters associated with antigen processing in lung carcinoma increases tumor-specific immune responses and survival. Cancer Res (2005) 0.98
Trogocytosis of MHC-I/peptide complexes derived from tumors and infected cells enhances dendritic cell cross-priming and promotes adaptive T cell responses. PLoS One (2008) 0.95
Weft, warp, and weave: the intricate tapestry of calcium channels regulating T lymphocyte function. Front Immunol (2013) 0.93
Epigenetic control of the immune escape mechanisms in malignant carcinomas. Mol Cell Biol (2007) 0.92
A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers. J Infect Dis (2009) 0.92
Combining the antigen processing components TAP and Tapasin elicits enhanced tumor-free survival. Clin Cancer Res (2008) 0.91
TAP expression reduces IL-10 expressing tumor infiltrating lymphocytes and restores immunosurveillance against melanoma. Int J Cancer (2007) 0.89
A unique carrier for delivery of therapeutic compounds beyond the blood-brain barrier. PLoS One (2008) 0.89
Dendritic cell cross-priming is essential for immune responses to Listeria monocytogenes. PLoS One (2009) 0.88
The immunostimulatory activity of unmethylated and methylated CpG oligodeoxynucleotide is dependent on their ability to colocalize with TLR9 in late endosomes. J Immunol (2010) 0.88
Direct quantitative determination of ceramide glycosylation in vivo: a new approach to evaluate cellular enzyme activity of glucosylceramide synthase. J Lipid Res (2009) 0.87
Adenovirus E3-6.7K maintains calcium homeostasis and prevents apoptosis and arachidonic acid release. J Virol (2002) 0.86
CTL-dependent and -independent antitumor immunity is determined by the tumor not the vaccine. J Immunol (2004) 0.86
Inhaled corticosteroids and the risk of pneumonia in Medicare patients with COPD. Curr Med Res Opin (2012) 0.85
The adenovirus E3-6.7K protein adopts diverse membrane topologies following posttranslational translocation. J Virol (2004) 0.84
Identification of mechanisms underlying transporter associated with antigen processing deficiency in metastatic murine carcinomas. Cancer Res (2005) 0.84
Evaluation of anticancer agents using flow cytometry analysis of cancer stem cells. Methods Mol Biol (2011) 0.83
[Controlled clinical trials of initial observation on therapeutic effects of moxibustion for osteoarthritis of the knee: multi-center clinical effect]. Zhongguo Gu Shang (2009) 0.82
Identification of a novel immunosubversion mechanism mediated by a virologue of the B-lymphocyte receptor TACI. Clin Vaccine Immunol (2007) 0.82
Human albumin prevents 6-hydroxydopamine-induced loss of tyrosine hydroxylase in in vitro and in vivo. PLoS One (2012) 0.81
Priming of immune responses against transporter associated with antigen processing (TAP)-deficient tumours: tumour direct priming. Immunology (2009) 0.81
Calorimetric studies of melanotransferrin (p97) and its interaction with iron. J Biol Chem (2005) 0.80
The opposite effects of doxorubicin on bone marrow stem cells versus breast cancer stem cells depend on glucosylceramide synthase. Int J Biochem Cell Biol (2012) 0.80
Effect of B7.1 costimulation on T-cell based immunity against TAP-negative cancer can be facilitated by TAP1 expression. PLoS One (2009) 0.79
The human melanoma associated protein melanotransferrin promotes endothelial cell migration and angiogenesis in vivo. Eur J Cell Biol (2002) 0.79
Novel immune function for the TRPV1 channel in T lymphocytes. Channels (Austin) (2014) 0.79
Diffusion of calcitonin through the wall of the root canal. Braz Oral Res (2004) 0.78
Identification of a novel route of iron transcytosis across the mammalian blood-brain barrier. Microcirculation (2003) 0.78
Cessation of neoangiogenesis in Alzheimer's disease follows amyloid-beta immunization. Sci Rep (2013) 0.78
In vivo survivors of transformed mouse ovarian surface epithelial cells display diverse phenotypes for gene expression and tumorigenicity. Tumour Biol (2008) 0.78
Tumour immunity and T cell memory are induced by low dose inoculation with a non-replicating adenovirus encoding TAP1. Vaccine (2006) 0.77
Effective indium-doped zinc oxide buffer layer on silver nanowires for electrically highly stable, flexible, transparent, and conductive composite electrodes. ACS Appl Mater Interfaces (2013) 0.77
p97 as a biomarker for Alzheimer disease. Front Biosci (2002) 0.77
A cyclin-dependent protein kinase homologue associated with the basal body domains in the ciliate Tetrahymena thermophila. Biochim Biophys Acta (2002) 0.76
Deletion of the GPI pre-anchor sequence in human p97--a general approach for generating the soluble form of GPI-linked proteins. Protein Expr Purif (2004) 0.75
Preparation, characterization, and photoelectric properties of a covalently self-assembled monolayer of ferrocenyl hemicyanine. J Nanosci Nanotechnol (2011) 0.75
Low-haze light extraction from organic light-emitting diode lighting with auxiliary electrode by selective microlens arrays. Opt Lett (2013) 0.75
[Evaluation of the clinical effect of knee osteoarthritis treated with moxibustion according to WHOQOL-BREF]. Zhongguo Gu Shang (2009) 0.75