| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
VEGF-Trap: a VEGF blocker with potent antitumor effects.
|
Proc Natl Acad Sci U S A
|
2002
|
8.10
|
|
2
|
Angiopoietin-2 is required for postnatal angiogenesis and lymphatic patterning, and only the latter role is rescued by Angiopoietin-1.
|
Dev Cell
|
2002
|
6.41
|
|
3
|
VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment.
|
J Clin Invest
|
2004
|
5.59
|
|
4
|
Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab.
|
Angiogenesis
|
2012
|
4.42
|
|
5
|
Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity.
|
Nat Med
|
2005
|
3.18
|
|
6
|
Agouti-related protein-deficient mice display an age-related lean phenotype.
|
Cell Metab
|
2005
|
2.75
|
|
7
|
Inhibition of hemangiogenesis and lymphangiogenesis after normal-risk corneal transplantation by neutralizing VEGF promotes graft survival.
|
Invest Ophthalmol Vis Sci
|
2004
|
2.27
|
|
8
|
Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells.
|
J Clin Invest
|
2002
|
2.26
|
|
9
|
Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference.
|
Proc Natl Acad Sci U S A
|
2004
|
2.23
|
|
10
|
Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo.
|
Am J Pathol
|
2002
|
2.20
|
|
11
|
VEGF Trap complex formation measures production rates of VEGF, providing a biomarker for predicting efficacious angiogenic blockade.
|
Proc Natl Acad Sci U S A
|
2007
|
2.19
|
|
12
|
Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF.
|
J Clin Invest
|
2002
|
1.95
|
|
13
|
VEGF-TRAP(R1R2) suppresses choroidal neovascularization and VEGF-induced breakdown of the blood-retinal barrier.
|
J Cell Physiol
|
2003
|
1.71
|
|
14
|
Suppression of diabetic retinopathy with angiopoietin-1.
|
Am J Pathol
|
2002
|
1.68
|
|
15
|
VEGF blockade inhibits angiogenesis and reepithelialization of endometrium.
|
FASEB J
|
2008
|
1.48
|
|
16
|
Vascular endothelial growth factor regulates reendothelialization and neointima formation in a mouse model of arterial injury.
|
Circulation
|
2004
|
1.45
|
|
17
|
VEGF-mediated inflammation precedes angiogenesis in adult brain.
|
Exp Neurol
|
2004
|
1.39
|
|
18
|
Effect of VEGF trap on normal retinal vascular development and oxygen-induced retinopathy in the dog.
|
Invest Ophthalmol Vis Sci
|
2011
|
1.33
|
|
19
|
Tlx acts as a proangiogenic switch by regulating extracellular assembly of fibronectin matrices in retinal astrocytes.
|
J Clin Invest
|
2006
|
1.31
|
|
20
|
Prevention of thecal angiogenesis, antral follicular growth, and ovulation in the primate by treatment with vascular endothelial growth factor Trap R1R2.
|
Endocrinology
|
2002
|
1.30
|
|
21
|
Promotion of graft survival by vascular endothelial growth factor a neutralization after high-risk corneal transplantation.
|
Arch Ophthalmol
|
2008
|
1.27
|
|
22
|
VEGF-dependent conjunctivalization of the corneal surface.
|
Invest Ophthalmol Vis Sci
|
2003
|
1.17
|
|
23
|
The Dll4/Notch pathway controls postangiogenic blood vessel remodeling and regression by modulating vasoconstriction and blood flow.
|
Blood
|
2011
|
1.13
|
|
24
|
Angiopoietin-2-driven vascular remodeling in airway inflammation.
|
Am J Pathol
|
2010
|
1.07
|
|
25
|
A subretinal matrigel rat choroidal neovascularization (CNV) model and inhibition of CNV and associated inflammation and fibrosis by VEGF trap.
|
Invest Ophthalmol Vis Sci
|
2010
|
1.06
|
|
26
|
Hemochorial placentation in the primate: expression of vascular endothelial growth factor, angiopoietins, and their receptors throughout pregnancy.
|
Biol Reprod
|
2002
|
1.06
|
|
27
|
Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice.
|
Diabetes
|
2004
|
1.01
|
|
28
|
The anti-inflammatory actions of angiopoietin-1.
|
EXS
|
2005
|
0.95
|
|
29
|
Single injections of vascular endothelial growth factor trap block ovulation in the macaque and produce a prolonged, dose-related suppression of ovarian function.
|
J Clin Endocrinol Metab
|
2004
|
0.95
|
|
30
|
Dexamethasone treatment and ICAM-1 deficiency impair VEGF-induced angiogenesis in adult brain.
|
J Vasc Res
|
2007
|
0.90
|
|
31
|
The role of vascular endothelial growth factor and estradiol in the regulation of endometrial angiogenesis and cell proliferation in the marmoset.
|
Endocrinology
|
2008
|
0.88
|
|
32
|
BDNF: a missing link between sympathetic dysfunction and inflammatory disease?
|
J Neuroimmunol
|
2006
|
0.87
|
|
33
|
Expression, localization and hormonal control of angiopoietin-1 in the rhesus macaque endometrium: potential role in spiral artery growth.
|
Mol Hum Reprod
|
2006
|
0.86
|
|
34
|
Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5.
|
Proc Natl Acad Sci U S A
|
2005
|
0.85
|
|
35
|
Inhibition of delta-like ligand 4 induces luteal hypervascularization followed by functional and structural luteolysis in the primate ovary.
|
Endocrinology
|
2012
|
0.84
|
|
36
|
Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses.
|
Pain
|
2007
|
0.84
|
|
37
|
VEGF Trap(R1R2) suppresses experimental corneal angiogenesis.
|
Eur J Ophthalmol
|
2010
|
0.81
|
|
38
|
Vascular endothelial growth factor mediates the estrogen-induced breakdown of tight junctions between and increase in proliferation of microvessel endothelial cells in the baboon endometrium.
|
Endocrinology
|
2008
|
0.81
|
|
39
|
Prevention of experimental choroidal neovascularization and resolution of active lesions by VEGF trap in nonhuman primates.
|
Arch Ophthalmol
|
2011
|
0.81
|
|
40
|
Vascular endothelial growth factor Trap suppresses ovarian function at all stages of the luteal phase in the macaque.
|
J Clin Endocrinol Metab
|
2005
|
0.79
|
|
41
|
Administration of vascular endothelial growth factor Trap during the 'post-angiogenic' period of the luteal phase causes rapid functional luteolysis and selective endothelial cell death in the marmoset.
|
Reproduction
|
2006
|
0.79
|
|
42
|
Inhibition of vascular endothelial growth factor during the postovulatory period prevents pregnancy in the marmoset.
|
Contraception
|
2010
|
0.75
|