| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Antitumor benzothiazoles. 26.(1) 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines.
|
J Med Chem
|
2006
|
1.51
|
|
2
|
Elucidation of thioredoxin as a molecular target for antitumor quinols.
|
Cancer Res
|
2005
|
1.13
|
|
3
|
Synthesis and biological properties of benzothiazole, benzoxazole, and chromen-4-one analogues of the potent antitumor agent 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (PMX 610, NSC 721648).
|
J Med Chem
|
2008
|
0.98
|
|
4
|
Quinols as novel therapeutic agents. 2.(1) 4-(1-Arylsulfonylindol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-ones and related agents as potent and selective antitumor agents.
|
J Med Chem
|
2005
|
0.85
|
|
5
|
Antitumor quinol PMX464 is a cytocidal anti-trypanosomal inhibitor targeting trypanothione metabolism.
|
J Biol Chem
|
2011
|
0.80
|
|
6
|
Antitumour properties of fluorinated benzothiazole-substituted hydroxycyclohexa-2,5-dienones ('quinols').
|
Bioorg Med Chem Lett
|
2006
|
0.78
|
|
7
|
Induction of tumor cell death through targeting tubulin and evoking dysregulation of cell cycle regulatory proteins by multifunctional cinnamaldehydes.
|
PLoS One
|
2012
|
0.77
|
|
8
|
Synthesis of antitumour (1H-1,2,3-triazol-4-yl)-4-hydroxycyclohexa-2,5-dien-1-ones by copper-catalysed Huisgen cycloadditions.
|
Org Biomol Chem
|
2010
|
0.77
|
|
9
|
Heteroaromatic 4-arylquinols are novel inducers of nuclear factor-erythroid 2-related factor 2 (Nrf2).
|
Eur J Pharmacol
|
2010
|
0.76
|
|
10
|
3-(2-oxoethylidene)indolin-2-one derivatives activate Nrf2 and inhibit NF-κB: potential candidates for chemoprevention.
|
ChemMedChem
|
2014
|
0.76
|