Published in Mol Endocrinol on January 05, 2006
Role of the GATA family of transcription factors in endocrine development, function, and disease. Mol Endocrinol (2008) 1.81
The Mediator complex and transcription regulation. Crit Rev Biochem Mol Biol (2013) 1.64
The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220. Proc Natl Acad Sci U S A (2006) 1.30
Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation. J Biol Chem (2008) 1.22
MED1 phosphorylation promotes its association with mediator: implications for nuclear receptor signaling. Mol Cell Biol (2008) 1.18
MiR-205 silences MED1 in hypoxic primary human trophoblasts. FASEB J (2010) 1.17
Med1 plays a critical role in the development of tamoxifen resistance. Carcinogenesis (2012) 1.13
Coactivators in PPAR-Regulated Gene Expression. PPAR Res (2010) 1.04
A composite intronic element directs dynamic binding of the progesterone receptor and GATA-2. Mol Endocrinol (2008) 1.04
A genome-wide RNA interference screen identifies a differential role of the mediator CDK8 module subunits for GATA/ RUNX-activated transcription in Drosophila. Mol Cell Biol (2010) 1.01
The Med1 subunit of transcriptional mediator plays a central role in regulating CCAAT/enhancer-binding protein-beta-driven transcription in response to interferon-gamma. J Biol Chem (2008) 0.99
Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptor-mediated gene transcription and breast cancer cell growth. J Biol Chem (2011) 0.98
Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1. Proc Natl Acad Sci U S A (2010) 0.95
NF-Y recruits both transcription activator and repressor to modulate tissue- and developmental stage-specific expression of human γ-globin gene. PLoS One (2012) 0.90
GATA2 mediates thyrotropin-releasing hormone-induced transcriptional activation of the thyrotropin β gene. PLoS One (2011) 0.87
The thyroid axis is regulated by NCoR1 via its actions in the pituitary. Endocrinology (2012) 0.86
A Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoter. Mol Endocrinol (2009) 0.82
Med1 subunit of the mediator complex in nuclear receptor-regulated energy metabolism, liver regeneration, and hepatocarcinogenesis. Gene Expr (2014) 0.80
Mediator subunit MED1 is a T3-dependent and T3-independent coactivator on the thyrotropin β gene promoter. Biochem Biophys Res Commun (2013) 0.75
The Colorado thyroid disease prevalence study. Arch Intern Med (2000) 7.84
The origin of human aneuploidy: where we have been, where we are going. Hum Mol Genet (2007) 3.72
A comparison of recombinant human thyrotropin and thyroid hormone withdrawal for the detection of thyroid remnant or cancer. J Clin Endocrinol Metab (1999) 1.92
L-Thyroxine therapy in subclinical hypothyroidism. A double-blind, placebo-controlled trial. Ann Intern Med (1984) 1.88
Thyroid hormone regulates the mouse thyrotropin beta-subunit gene promoter in transfected primary thyrotropes. J Biol Chem (1989) 1.84
Do traditional symptoms of hypothyroidism correlate with biochemical disease? J Gen Intern Med (1997) 1.75
Subclinical hypothyroidism is mild thyroid failure and should be treated. J Clin Endocrinol Metab (2001) 1.72
Noninvasive evaluation of cardiac function in hypothyroidism. Response to gradual thyroxine replacement. N Engl J Med (1977) 1.55
Thyroid hormone resistance syndromes. Am J Med (1993) 1.54
Decreased bone density in hyperprolactinemic women. N Engl J Med (1980) 1.53
Hypothyroidism-induced macroorchidism: use of a gonadotropin-releasing hormone agonist to understand its mechanism and augment adult stature. J Clin Endocrinol Metab (1995) 1.43
Secondary malignancy of the thyroid gland: a case report and review of the literature. Thyroid (1994) 1.41
Subclinical hyperthyroidism and reduced bone density as a possible result of prolonged suppression of the pituitary-thyroid axis with L-thyroxine. Am J Med (1987) 1.34
Osteoporosis in men with hyperprolactinemic hypogonadism. Ann Intern Med (1986) 1.34
Transcriptional regulation of the thyrotropin subunit genes by thyroid hormone. J Biol Chem (1985) 1.33
Agranulocytosis associated with antithyroid drugs. Effects of patient age and drug dose. Ann Intern Med (1983) 1.29
Suppression of pituitary TSH secretion in the patient with a hyperfunctioning thyroid nodule. J Clin Invest (1973) 1.27
Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function. Mol Endocrinol (2006) 1.27
Spectrum of pituitary alterations with mild and severe thyroid impairment. J Clin Endocrinol Metab (1978) 1.24
Enhancer-mediated high level expression of mouse pituitary glycoprotein hormone alpha-subunit transgene in thyrotropes, gonadotropes, and developing pituitary gland. Mol Endocrinol (1994) 1.20
Substrate cycling between gluconeogenesis and glycolysis in euthyroid, hypothyroid, and hyperthyroid man. J Clin Invest (1985) 1.20
GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway. Mol Cell Biol (2006) 1.17
Signaling pathways responsible for fetal gene induction in the failing human heart: evidence for altered thyroid hormone receptor gene expression. Circulation (2001) 1.17
The effect of glucocorticoid administration on human pituitary secretion of thyrotropin and prolactin. J Clin Endocrinol Metab (1976) 1.15
Evaluation of acromegaly by radioimmunoassay of somatomedin-C. N Engl J Med (1979) 1.13
Pituitary secretion of free alpha and beta subunit of human thyrotropin in patients with thyroid disorders. J Clin Endocrinol Metab (1975) 1.10
Policy decisions on endocrine disruptors should be based on science across disciplines: a response to Dietrich et al. Endocrinology (2013) 1.08
Reduction of plasma immunoreactive somatomedin C during fasting in humans. J Clin Endocrinol Metab (1981) 1.08
Thyrotropin-induced hyperthyroidism: use of alpha and beta subunit levels to identify patients with pituitary tumors. J Clin Endocrinol Metab (1977) 1.05
Secretion of alpha subunit of glycoprotein hormones by pituitary adenomas. J Clin Endocrinol Metab (1976) 1.05
Complications of surgery in hypothyroid patients. Am J Med (1984) 1.03
Prediction and reversal of blunted ventilatory responsiveness in patients with hypothyroidism. Am J Med (1988) 1.01
Development of the volunteer peer educator role in a community Cardiovascular Health Awareness Program (CHAP): a process evaluation in two communities. J Community Health (2009) 1.01
Antineutrophil autoantibodies in Graves' disease. Implications of thyrotropin binding to neutrophils. J Clin Invest (1985) 1.00
Cell-specific expression of the mouse glycoprotein hormone alpha-subunit gene requires multiple interacting DNA elements in transgenic mice and cultured cells. Mol Endocrinol (1998) 1.00
The thyrotropin beta-subunit gene is repressed by thyroid hormone in a novel thyrotrope cell line, mouse T alphaT1 cells. Endocrinology (1998) 1.00
Reversible alteration of the visual evoked potential in hypothyroidism. Am J Med (1984) 1.00
Peripheral responses to thyroid hormone before and after L-thyroxine therapy in patients with subclinical hypothyroidism. J Clin Endocrinol Metab (1981) 0.99
Successful treatment of solitary toxic thyroid nodules with relatively low-dose iodine-131, with low prevalence of hypothyroidism. Ann Intern Med (1984) 0.99
Impact of capacity reductions in acute public-sector inpatient psychiatric services. Psychiatr Serv (2012) 0.98
Intrapancreatic accessory spleen: CT appearance and differential diagnosis. Abdom Imaging (2012) 0.98
Molecular biology of thyrotropin. Endocr Rev (1989) 0.97
Therapy of primary hypothyroidism with L-triiodothyronine: discordant cardiac and pituitary responses. Clin Endocrinol (Oxf) (1980) 0.97
Pit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoter. J Biol Chem (1997) 0.95
Hormone production in clinically nonfunctioning pituitary adenomas. J Neurosurg (1987) 0.94
An alpha-subunit-secreting cell line derived from a mouse thyrotrope tumor. Mol Endocrinol (1990) 0.94
Rapid pituitary and peripheral tissue responses to intravenous L-triiodothyronine in hypothyroidism. J Clin Endocrinol Metab (1983) 0.93
Regulation of the alpha and thyrotropin beta-subunit messenger ribonucleic acids by thyroid hormones. Endocrinology (1985) 0.92
Transcriptional regulation of thyrotropin subunit genes by thyrotropin-releasing hormone and dopamine in pituitary cell culture. J Biol Chem (1986) 0.92
Acute metabolic responses in myxedema to large doses of intravenous L-thyroxine. Ann Intern Med (1972) 0.92
Alkaline phosphatase isoenzyme patterns in hyperthyroidism. Ann Intern Med (1979) 0.91
Glycoprotein hormone genes are expressed in clinically nonfunctioning pituitary adenomas. J Clin Invest (1987) 0.91
Metabolic clearance and production rates of prolactin in man. J Clin Invest (1979) 0.91
Pure alpha-secreting pituitary adenomas. N Engl J Med (1981) 0.90
Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis. Endocrinology (2005) 0.89
Metabolic clearance and secretion rates of subunits of human thyrotropin. J Clin Invest (1977) 0.89
Methimazole pharmacology in the rat: studies using a newly developed radioimmunoassay for methimazole. Endocrinology (1984) 0.89
Early peripheral responses to intravenous L-thyroxine in primary hypothyroidism. Am J Med (1982) 0.89
Analysis of DNA sequences required for pituitary-specific expression of the glycoprotein hormone alpha-subunit gene. Mol Endocrinol (1992) 0.89
Management practices among primary care physicians and thyroid specialists in the care of hypothyroid patients. Thyroid (2001) 0.89
Effects of hydrocortisone on pulsatile pituitary glycoprotein secretion. J Clin Endocrinol Metab (1994) 0.89
Regulation by thyroxine of the mRNA encoding the alpha subunit of mouse thyrotropin. J Biol Chem (1983) 0.89
Metabolic clearance and production rates of human thyrotropin. J Clin Invest (1974) 0.89
Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function. Mol Cell Biol (2010) 0.88
Nuclear factor κB-dependent regulation of angiogenesis, and metastasis in an in vivo model of thyroid cancer is associated with secreted interleukin-8. J Clin Endocrinol Metab (2014) 0.88
Oestrogen blocks the nuclear entry of SOX9 in the developing gonad of a marsupial mammal. BMC Biol (2010) 0.87
Clinically silent hypersecretion of growth hormone in patients with pituitary tumors. J Neurosurg (1987) 0.86
Estradiol treatment of acromegaly. Reduction of immunoreactive somatomedin-C and improvement in metabolic status. Am J Med (1980) 0.86
Propylthiouracil (PTU) pharmacology in the rat. II. Effects of PTU on thyroid function. Endocrinology (1983) 0.86
Acute effects of propylthiouracil (PTU) on thyroidal iodide organification and peripheral iodothyronine deiodination: correlation with serum PTU levels measured by radioimmunoassay. J Clin Endocrinol Metab (1982) 0.85
Hyperthyroxinemia in patients treated with high-dose propranolol. Am J Med (1982) 0.85
Domains of Pit-1 required for transcriptional synergy with GATA-2 on the TSH beta gene. Mol Cell Endocrinol (2002) 0.85
PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism. Mol Endocrinol (2011) 0.84
Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer. Mol Cancer (2014) 0.84
Growth arrest of thyrotropic tumors by thyroid hormone is correlated with novel changes in Wnt-10A. Mol Cell Endocrinol (2005) 0.84
Elevated thyroxine levels due to increased thyroxine-binding globulin in acute hepatitis. Am J Med (1983) 0.84
Thyrotrope expression and thyroid hormone inhibition map to different regions of the mouse glycoprotein hormone alpha-subunit gene promoter. Endocrinology (1990) 0.84
Natural history of carotid artery occlusion. Ann Vasc Surg (2012) 0.84
Radioactive iodine therapy and breast cancer. A follow-up study of hyperthyroid women. Am J Epidemiol (1988) 0.84
Thyroid hormone receptor beta2 promoter activity in pituitary cells is regulated by Pit-1. J Biol Chem (1996) 0.84
Discordant changes in pituitary concentrations of LH and TSH subunits following hormonal manipulation. Metabolism (1984) 0.83
Organization and nucleotide sequence of the gene encoding the beta-subunit of murine thyrotropin. DNA (1988) 0.83
Augmentation of pituitary thyrotrophin response to thyrotrophin releasing hormone during subphysiological tri-iodothyroinine therapy in hypothyroidism. Clin Endocrinol (Oxf) (1979) 0.83
Analysis of Pit-1 in regulating mouse TSH beta promoter activity in thyrotropes. Mol Cell Endocrinol (1993) 0.83
Divergent changes in murine pituitary concentration of free alpha- and thyrotropin beta-subunits in hypothyroidism and after thyroxine administration. Endocrinology (1983) 0.83
Follicle-stimulating hormone- and alpha-subunit-secreting pituitary tumor treated with bromocriptine. J Clin Endocrinol Metab (1985) 0.83
Effect of thyroid hormone on T3-receptor mRNA levels and growth of thyrotropic tumors. Mol Cell Endocrinol (1993) 0.83
Use of adjunctive potassium iodide after radioactive iodine (131I) treatment of Graves' hyperthyroidism. J Clin Endocrinol Metab (1983) 0.83
Triiodothyronine (T3) regulation of thyrotropin subunit gene transcription is proportional to T3 nuclear receptor occupancy. Endocrinology (1986) 0.82
Mouse pituitary tumor line secreting only the alpha-subunit of the glycoprotein hormones: development from a thyrotropic tumor. Endocrinology (1983) 0.82
Organization and nucleotide sequence of the mouse alpha-subunit gene of the pituitary glycoprotein hormones. DNA (1988) 0.82
Structural and functional characterization of the genomic locus encoding the murine beta 2 thyroid hormone receptor. Mol Endocrinol (1994) 0.82
Methimazole pharmacology in man: studies using a newly developed radioimmunoassay for methimazole. J Clin Endocrinol Metab (1984) 0.81
Effects of dopamine and somatostatin on pulsatile pituitary glycoprotein secretion. J Clin Endocrinol Metab (1992) 0.81
Pulsatile TSH secretion during 48-hour continuous TRH infusions. Thyroid (1993) 0.81
Dopaminergic modulation of TSH and its subunits: in vivo and in vitro studies. Clin Endocrinol (Oxf) (1983) 0.81
Familial thyroid hormone resistance. Metabolism (1982) 0.81
Pulsatile secretion of thyrotropin in man. J Clin Endocrinol Metab (1986) 0.81