Biodendrimer-based hydrogel scaffolds for cartilage tissue repair.

PubWeight™: 1.13‹?› | Rank: Top 10%

🔗 View Article (PMID 16398530)

Published in Biomacromolecules on January 01, 2006

Authors

Serge H M Söntjens1, Dana L Nettles, Michael A Carnahan, Lori A Setton, Mark W Grinstaff

Author Affiliations

1: Departments of Chemistry and Biomedical Engineering, Boston University, Metcalf Center for Science and Engineering, 590 Commonwealth Avenue, Boston, MA 02215, USA.

Articles citing this

Cell encapsulation in biodegradable hydrogels for tissue engineering applications. Tissue Eng Part B Rev (2008) 2.63

Engineering cartilage tissue. Adv Drug Deliv Rev (2007) 2.08

Hydrogels for the repair of articular cartilage defects. Tissue Eng Part B Rev (2011) 1.35

Cartilage tissue engineering: towards a biomaterial-assisted mesenchymal stem cell therapy. Curr Stem Cell Res Ther (2009) 1.22

Nanocomposite hydrogels for biomedical applications. Biotechnol Bioeng (2013) 1.15

Enzyme-mediated redox initiation for hydrogel generation and cellular encapsulation. Biomacromolecules (2009) 1.12

The effects of substrate stiffness on the in vitro activation of macrophages and in vivo host response to poly(ethylene glycol)-based hydrogels. J Biomed Mater Res A (2012) 1.11

Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation and in vitro and in vivo evaluation. Mol Pharm (2011) 0.96

Anionic amphiphilic dendrimers as antibacterial agents. J Am Chem Soc (2008) 0.95

Designing hydrogel adhesives for corneal wound repair. Biomaterials (2007) 0.94

Three-dimensional scaffolds for tissue engineering: the importance of uniformity in pore size and structure. Langmuir (2010) 0.93

Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers. Biomacromolecules (2008) 0.92

Nitric oxide-releasing dendrimers as antibacterial agents. Biomacromolecules (2012) 0.92

An enzyme-sensitive PEG hydrogel based on aggrecan catabolism for cartilage tissue engineering. Adv Healthc Mater (2014) 0.87

Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds. Tissue Eng Part A (2010) 0.87

Synthesis and characterization of dendron cross-linked PEG hydrogels as corneal adhesives. Biomacromolecules (2011) 0.85

Strategic design and fabrication of engineered scaffolds for articular cartilage repair. J Funct Biomater (2012) 0.85

Hyperbranched polyester hydrogels with controlled drug release and cell adhesion properties. Biomacromolecules (2013) 0.85

Synthesis and characterization of photocurable polyamidoamine dendrimer hydrogels as a versatile platform for tissue engineering and drug delivery. Biomacromolecules (2010) 0.83

Composites of Polymer Hydrogels and Nanoparticulate Systems for Biomedical and Pharmaceutical Applications. Nanomaterials (Basel) (2015) 0.78

Dendrimeric systems and their applications in ocular drug delivery. ScientificWorldJournal (2013) 0.77

Understanding Peptide Oligomeric State in Langmuir Monolayers of Amphiphilic 3-Helix Bundle-Forming Peptide-PEG Conjugates. Biomacromolecules (2016) 0.75

Synthesis and characterization of degradable bioconjugated hydrogels with hyperbranched multifunctional cross-linkers. Acta Biomater (2010) 0.75

Characterization of the chondrocyte secretome in photoclickable poly(ethylene glycol) hydrogels. Biotechnol Bioeng (2017) 0.75

Articles by these authors

Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues. Arthritis Rheum (2010) 3.45

The role of biomechanics and inflammation in cartilage injury and repair. Clin Orthop Relat Res (2004) 1.89

Effect of contrast agent charge on visualization of articular cartilage using computed tomography: exploiting electrostatic interactions for improved sensitivity. J Am Chem Soc (2009) 1.71

The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage. Ann N Y Acad Sci (2006) 1.71

Synthesis and in vitro evaluation of enzymatically cross-linked elastin-like polypeptide gels for cartilaginous tissue repair. Tissue Eng (2006) 1.68

Swelling and mechanical behaviors of chemically cross-linked hydrogels of elastin-like polypeptides. Biomacromolecules (2003) 1.66

The biomechanical role of the chondrocyte pericellular matrix in articular cartilage. Acta Biomater (2005) 1.57

Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage. J Biomech (2007) 1.55

X-ray-computed tomography contrast agents. Chem Rev (2012) 1.52

Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. Arthritis Res Ther (2010) 1.48

Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. Biomaterials (2006) 1.48

Photocrosslinkable hyaluronan as a scaffold for articular cartilage repair. Ann Biomed Eng (2004) 1.47

Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system. J Am Chem Soc (2009) 1.46

Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage. J Biomech (2005) 1.41

Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair. Biomacromolecules (2002) 1.39

Discussion: "On the Thermodynamical Admissibility of the Triphasic Theory of Charged Hydrated Tissues" (Huyghe, J. M., Wilson, W., and Malakpoor, K., ASME J. Biomech. Eng., 2009, 131, p. 044504). J Biomech Eng (2009) 1.39

Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J Control Release (2011) 1.39

Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. Arthritis Rheum (2007) 1.38

Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. Biomacromolecules (2007) 1.37

Molecular phenotypes of notochordal cells purified from immature nucleus pulposus. Eur Spine J (2006) 1.36

Therapeutic and diagnostic applications of dendrimers for cancer treatment. Adv Drug Deliv Rev (2008) 1.35

In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair. Biomacromolecules (2007) 1.30

A thermally responsive biopolymer for intra-articular drug delivery. J Control Release (2006) 1.30

Biomedical applications of dendrimers: a tutorial. Chem Soc Rev (2010) 1.28

Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro. Cancer Res (2006) 1.27

The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. J Biomech Eng (2003) 1.23

DNA-PEG-DNA triblock macromolecules for reagentless DNA detection. J Am Chem Soc (2004) 1.23

Introduction: disc degeneration: summary. Spine (Phila Pa 1976) (2004) 1.21

Charge-reversal amphiphiles for gene delivery. J Am Chem Soc (2004) 1.21

Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model. J Biomech Eng (2006) 1.19

Applications of elastin-like polypeptides in tissue engineering. Adv Drug Deliv Rev (2010) 1.19

Zonal uniformity in mechanical properties of the chondrocyte pericellular matrix: micropipette aspiration of canine chondrons isolated by cartilage homogenization. Ann Biomed Eng (2005) 1.19

Differential effects of static and dynamic compression on meniscal cell gene expression. J Orthop Res (2003) 1.19

Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity. Biochem Biophys Res Commun (2002) 1.18

Cationic contrast agents improve quantification of glycosaminoglycan (GAG) content by contrast enhanced CT imaging of cartilage. J Orthop Res (2010) 1.18

Biologically responsive polymeric nanoparticles for drug delivery. Adv Mater (2012) 1.17

Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis. Arthritis Res Ther (2012) 1.16

Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions. J Am Chem Soc (2004) 1.16

Region-specific constitutive gene expression in the adult porcine meniscus. J Orthop Res (2006) 1.15

Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. Arthritis Rheum (2009) 1.15

Direct measurement of the Poisson's ratio of human patella cartilage in tension. J Biomech Eng (2002) 1.14

Hybrid dendritic-linear polyester-ethers for in situ photopolymerization. J Am Chem Soc (2002) 1.14

High-resolution determination of soft tissue deformations using MRI and first-order texture correlation. IEEE Trans Med Imaging (2004) 1.13

Superhydrophobic materials for tunable drug release: using displacement of air to control delivery rates. J Am Chem Soc (2012) 1.12

Tunable pores for measuring concentrations of synthetic and biological nanoparticle dispersions. Biosens Bioelectron (2011) 1.11

Integrin expression in cells of the intervertebral disc. J Anat (2004) 1.10

Static compression induces zonal-specific changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro. Matrix Biol (2004) 1.10

Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc. J Orthop Res (2007) 1.09

Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions. PLoS One (2011) 1.09

Dendritic molecular capsules for hydrophobic compounds. J Am Chem Soc (2003) 1.07

Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus. Biophys J (2008) 1.06

Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells. J Orthop Res (2011) 1.05

Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. Connect Tissue Res (2009) 1.05

Contrast-enhanced CT with a high-affinity cationic contrast agent for imaging ex vivo bovine, intact ex vivo rabbit, and in vivo rabbit cartilage. Radiology (2012) 1.04

Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen. Arthritis Rheum (2008) 1.03

Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy. Spine (Phila Pa 1976) (2009) 1.03

Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins. Protein Sci (2009) 1.03

Ascorbic acid increases the severity of spontaneous knee osteoarthritis in a guinea pig model. Arthritis Rheum (2004) 1.02

Synthesis and properties of supramolecular ionic networks. J Am Chem Soc (2008) 1.02

Evaluating intra-articular drug delivery for the treatment of osteoarthritis in a rat model. Tissue Eng Part B Rev (2010) 1.02

Experimental and biphasic FEM determinations of the material properties and hydraulic permeability of the meniscus in tension. J Biomech Eng (2002) 1.01

Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration. Biomaterials (2013) 1.01

Supramolecular assemblies of nucleoside phosphocholine amphiphiles. J Am Chem Soc (2004) 1.00

Epitope tagging for tracking elastin-like polypeptides. Biomaterials (2005) 1.00

Conformationally gated electrochemical gene detection. Chembiochem (2004) 1.00

Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus. Biomech Model Mechanobiol (2006) 1.00

Synthesis and aqueous aggregation properties of amphiphilic surface-block dendrimers. Org Lett (2005) 0.99

A mechano-chemical model for the passive swelling response of an isolated chondron under osmotic loading. Biomech Model Mechanobiol (2006) 0.99

Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist. J Control Release (2008) 0.99

Prevention of in vivo lung tumor growth by prolonged local delivery of hydroxycamptothecin using poly(ester-carbonate)-collagen composites. J Control Release (2010) 0.99

Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist. J Orthop Res (2010) 0.98

Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. Spine (Phila Pa 1976) (2004) 0.98

3D superhydrophobic electrospun meshes as reinforcement materials for sustained local drug delivery against colorectal cancer cells. J Control Release (2012) 0.96

Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids. Org Biomol Chem (2008) 0.96

Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR. Ann Biomed Eng (2005) 0.96

In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model. Tissue Eng Part A (2008) 0.96

New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair. Arch Ophthalmol (2004) 0.96

Functional lipids and lipoplexes for improved gene delivery. Biochimie (2011) 0.96

Anionic amphiphilic dendrimers as antibacterial agents. J Am Chem Soc (2008) 0.95

Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases. Mol Pharm (2011) 0.95

An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration. Spine (Phila Pa 1976) (2008) 0.95

Measurement of intracellular strain on deformable substrates with texture correlation. J Biomech (2006) 0.94

Engineering porcine arteries: effects of scaffold modification. J Biomed Mater Res A (2003) 0.94

Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles. Nanoscale (2013) 0.94

Three-dimensional morphology of the pericellular matrix of intervertebral disc cells in the rat. J Anat (2007) 0.93

Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism. Arthritis Res Ther (2011) 0.93

Silver nanoparticle-catalyzed Diels-Alder cycloadditions of 2'-hydroxychalcones. J Am Chem Soc (2010) 0.93

Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers. Biomacromolecules (2008) 0.92

Cationic nucleoside lipids for gene delivery. Bioconjug Chem (2006) 0.92

Chondropathy after meniscal tear or partial meniscectomy in a canine model. J Orthop Res (2002) 0.92

Three-dimensional finite element modeling of pericellular matrix and cell mechanics in the nucleus pulposus of the intervertebral disk based on in situ morphology. Biomech Model Mechanobiol (2010) 0.92