Anionic amphiphilic dendrimers as antibacterial agents.

PubWeight™: 0.95‹?› | Rank: Top 15%

🔗 View Article (PMC 2673084)

Published in J Am Chem Soc on October 09, 2008

Authors

Steven R Meyers1, Frank S Juhn, Aaron P Griset, Nathanael R Luman, Mark W Grinstaff

Author Affiliations

1: Department of Biomedical Engineering, Metcalf Center for Science and Engineering, Boston University, Boston, Massachusetts, USA.

Articles cited by this

Solubilization of membranes by detergents. Biochim Biophys Acta (1975) 13.31

Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol (2001) 11.67

Designing dendrimers for biological applications. Nat Biotechnol (2005) 4.92

Dendrimers in biomedical applications--reflections on the field. Adv Drug Deliv Rev (2005) 3.39

Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev (2005) 3.27

About Dendrimers: Structure, Physical Properties, and Applications. Chem Rev (1999) 3.15

Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: hole formation and the relation to transport. Bioconjug Chem (2004) 2.66

A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas. Proc Natl Acad Sci U S A (2006) 2.55

Dendrimers and dendritic polymers in drug delivery. Drug Discov Today (2005) 2.37

PAMAM dendrimer-based multifunctional conjugate for cancer therapy: synthesis, characterization, and functionality. Biomacromolecules (2006) 2.17

Dendrimers in Supramolecular Chemistry: From Molecular Recognition to Self-Assembly. Chem Rev (1997) 2.05

The influence of surface modification on the cytotoxicity of PAMAM dendrimers. Int J Pharm (2003) 1.80

Quaternary ammonium functionalized poly(propylene imine) dendrimers as effective antimicrobials: structure-activity studies. Biomacromolecules (2000) 1.40

Therapeutic and diagnostic applications of dendrimers for cancer treatment. Adv Drug Deliv Rev (2008) 1.35

Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro. Cancer Res (2006) 1.27

Preclinical evaluation of sodium cellulose sulfate (Ushercell) as a contraceptive antimicrobial agent. J Androl (2002) 1.23

Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines. Bioconjug Chem (2006) 1.19

Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions. J Am Chem Soc (2004) 1.16

Hybrid dendritic-linear polyester-ethers for in situ photopolymerization. J Am Chem Soc (2002) 1.14

Poly(sodium 4-styrene sulfonate): an effective candidate topical antimicrobial for the prevention of sexually transmitted diseases. J Infect Dis (2000) 1.14

Biodendrimer-based hydrogel scaffolds for cartilage tissue repair. Biomacromolecules (2006) 1.13

Dendrimers as drug delivery vehicles: non-covalent interactions of bioactive compounds with dendrimers. Polym Int (2007) 1.07

Developmental toxicity of low generation PAMAM dendrimers in zebrafish. Toxicol Appl Pharmacol (2007) 1.06

Polystyrene-dendrimer amphiphilic block copolymers with a generation-dependent aggregation. Science (1995) 1.06

Synthesis and aqueous aggregation properties of amphiphilic surface-block dendrimers. Org Lett (2005) 0.99

New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair. Arch Ophthalmol (2004) 0.96

Designing hydrogel adhesives for corneal wound repair. Biomaterials (2007) 0.94

Photo cross-linkable Biodendrimers as ophthalmic adhesives for central lacerations and penetrating keratoplasties. Invest Ophthalmol Vis Sci (2007) 0.89

Hydrogels formed by multiple peptide ligation reactions to fasten corneal transplants. Bioconjug Chem (2006) 0.88

Articles by these authors

Many Microbe Microarrays Database: uniformly normalized Affymetrix compendia with structured experimental metadata. Nucleic Acids Res (2007) 3.80

Effect of contrast agent charge on visualization of articular cartilage using computed tomography: exploiting electrostatic interactions for improved sensitivity. J Am Chem Soc (2009) 1.71

X-ray-computed tomography contrast agents. Chem Rev (2012) 1.52

Photocrosslinkable hyaluronan as a scaffold for articular cartilage repair. Ann Biomed Eng (2004) 1.47

Expansile nanoparticles: synthesis, characterization, and in vivo efficacy of an acid-responsive polymeric drug delivery system. J Am Chem Soc (2009) 1.46

Local drug delivery strategies for cancer treatment: gels, nanoparticles, polymeric films, rods, and wafers. J Control Release (2011) 1.39

Therapeutic and diagnostic applications of dendrimers for cancer treatment. Adv Drug Deliv Rev (2008) 1.35

Biomedical applications of dendrimers: a tutorial. Chem Soc Rev (2010) 1.28

Dendrimer-encapsulated camptothecins: increased solubility, cellular uptake, and cellular retention affords enhanced anticancer activity in vitro. Cancer Res (2006) 1.27

DNA-PEG-DNA triblock macromolecules for reagentless DNA detection. J Am Chem Soc (2004) 1.23

Charge-reversal amphiphiles for gene delivery. J Am Chem Soc (2004) 1.21

Cationic contrast agents improve quantification of glycosaminoglycan (GAG) content by contrast enhanced CT imaging of cartilage. J Orthop Res (2010) 1.18

Biologically responsive polymeric nanoparticles for drug delivery. Adv Mater (2012) 1.17

Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions. J Am Chem Soc (2004) 1.16

Hybrid dendritic-linear polyester-ethers for in situ photopolymerization. J Am Chem Soc (2002) 1.14

Biodendrimer-based hydrogel scaffolds for cartilage tissue repair. Biomacromolecules (2006) 1.13

Superhydrophobic materials for tunable drug release: using displacement of air to control delivery rates. J Am Chem Soc (2012) 1.12

Tunable pores for measuring concentrations of synthetic and biological nanoparticle dispersions. Biosens Bioelectron (2011) 1.11

Dendritic molecular capsules for hydrophobic compounds. J Am Chem Soc (2003) 1.07

Contrast-enhanced CT with a high-affinity cationic contrast agent for imaging ex vivo bovine, intact ex vivo rabbit, and in vivo rabbit cartilage. Radiology (2012) 1.04

Identification of diverse carbon utilization pathways in Shewanella oneidensis MR-1 via expression profiling. Genome Inform (2007) 1.04

Synthesis and properties of supramolecular ionic networks. J Am Chem Soc (2008) 1.02

Supramolecular assemblies of nucleoside phosphocholine amphiphiles. J Am Chem Soc (2004) 1.00

Conformationally gated electrochemical gene detection. Chembiochem (2004) 1.00

Synthesis and aqueous aggregation properties of amphiphilic surface-block dendrimers. Org Lett (2005) 0.99

Prevention of in vivo lung tumor growth by prolonged local delivery of hydroxycamptothecin using poly(ester-carbonate)-collagen composites. J Control Release (2010) 0.99

3D superhydrophobic electrospun meshes as reinforcement materials for sustained local drug delivery against colorectal cancer cells. J Control Release (2012) 0.96

New dendritic adhesives for sutureless ophthalmic surgical procedures: in vitro studies of corneal laceration repair. Arch Ophthalmol (2004) 0.96

Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids. Org Biomol Chem (2008) 0.96

Functional lipids and lipoplexes for improved gene delivery. Biochimie (2011) 0.96

Exploiting dendrimer multivalency to combat emerging and re-emerging infectious diseases. Mol Pharm (2011) 0.95

Microscopy and tunable resistive pulse sensing characterization of the swelling of pH-responsive, polymeric expansile nanoparticles. Nanoscale (2013) 0.94

Engineering porcine arteries: effects of scaffold modification. J Biomed Mater Res A (2003) 0.94

Silver nanoparticle-catalyzed Diels-Alder cycloadditions of 2'-hydroxychalcones. J Am Chem Soc (2010) 0.93

Hydrogels for osteochondral repair based on photocrosslinkable carbamate dendrimers. Biomacromolecules (2008) 0.92

Cationic nucleoside lipids for gene delivery. Bioconjug Chem (2006) 0.92

A photopolymerized sealant for corneal lacerations. Cornea (2002) 0.92

The development of peptide-based interfacial biomaterials for generating biological functionality on the surface of bioinert materials. Biomaterials (2008) 0.91

Paclitaxel-eluting polymer film reduces locoregional recurrence and improves survival in a recurrent sarcoma model: a novel investigational therapy. Ann Surg Oncol (2011) 0.91

Poly-amido-saccharides: synthesis via anionic polymerization of a β-lactam sugar monomer. J Am Chem Soc (2012) 0.91

Lipophilic peptides for gene delivery. Bioconjug Chem (2008) 0.91

Comparison of sutures and dendritic polymer adhesives for corneal laceration repair in an in vivo chicken model. Arch Ophthalmol (2009) 0.90

Nucleic acid complexing glycosyl nucleoside-based amphiphile. Bioconjug Chem (2005) 0.90

Tantalum oxide nanoparticles for the imaging of articular cartilage using X-ray computed tomography: visualization of ex vivo/in vivo murine tibia and ex vivo human index finger cartilage. Angew Chem Int Ed Engl (2014) 0.90

The performance of expansile nanoparticles in a murine model of peritoneal carcinomatosis. Biomaterials (2010) 0.89

Photo cross-linkable Biodendrimers as ophthalmic adhesives for central lacerations and penetrating keratoplasties. Invest Ophthalmol Vis Sci (2007) 0.89

Prevention of nodal metastases in breast cancer following the lymphatic migration of paclitaxel-loaded expansile nanoparticles. Biomaterials (2012) 0.89

Hydrogels formed by multiple peptide ligation reactions to fasten corneal transplants. Bioconjug Chem (2006) 0.88

A nanopore-nanofiber mesh biosensor to control DNA translocation. J Am Chem Soc (2013) 0.87

Synthesis of atactic and isotactic poly(1,2-glycerol carbonate)s: degradable polymers for biomedical and pharmaceutical applications. J Am Chem Soc (2013) 0.87

Paclitaxel-loaded expansile nanoparticles delay local recurrence in a heterotopic murine non-small cell lung cancer model. Ann Thorac Surg (2011) 0.87

Supramolecular assemblies of DNA with neutral nucleoside amphiphiles. Chem Commun (Camb) (2005) 0.87

A new helper phospholipid for gene delivery. Chem Commun (Camb) (2008) 0.87

Biocompatible and bioactive surface modifications for prolonged in vivo efficacy. Chem Rev (2011) 0.87

Prevention of local tumor recurrence following surgery using low-dose chemotherapeutic polymer films. Ann Surg Oncol (2009) 0.86

Charge-reversal lipids, peptide-based lipids, and nucleoside-based lipids for gene delivery. Acc Chem Res (2012) 0.86

The self-assembly of anticancer camptothecin-dipeptide nanotubes: a minimalistic and high drug loading approach to increased efficacy. Chemistry (2014) 0.85

Directed assembly of PEGylated-peptide coatings for infection-resistant titanium metal. J Am Chem Soc (2009) 0.85

Synthesis and characterization of dendron cross-linked PEG hydrogels as corneal adhesives. Biomacromolecules (2011) 0.85

Direct-writing of polymer nanostructures: poly(thiophene) nanowires on semiconducting and insulating surfaces. J Am Chem Soc (2002) 0.85

In situ polymerized hydrogels for repairing scleral incisions used in pars plana vitrectomy procedures. ChemMedChem (2006) 0.85

A facile approach to robust superhydrophobic 3D coatings via connective-particle formation using the electrospraying process. Chem Commun (Camb) (2013) 0.85

Nanoparticle migration and delivery of Paclitaxel to regional lymph nodes in a large animal model. J Am Coll Surg (2012) 0.84

Synthesis, characterization, and in vitro transfection activity of charge-reversal amphiphiles for DNA delivery. Bioconjug Chem (2011) 0.84

Nucleoside phosphocholine amphiphile for in vitro DNA transfection. Mol Biosyst (2005) 0.84

Cationic nucleoside lipids based on a 3-nitropyrrole universal base for siRNA delivery. Bioconjug Chem (2009) 0.84

The effect of charge-reversal amphiphile spacer composition on DNA and siRNA delivery. Bioconjug Chem (2010) 0.84

Cytoreductive surgery and intraoperative administration of paclitaxel-loaded expansile nanoparticles delay tumor recurrence in ovarian carcinoma. Ann Surg Oncol (2012) 0.84

Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials. Ann Biomed Eng (2010) 0.84

In vitro activity of Paclitaxel-loaded polymeric expansile nanoparticles in breast cancer cells. Biomacromolecules (2013) 0.84

Functionalized hydrophobic poly(glycerol-co-ε-caprolactone) depots for controlled drug release. Biomacromolecules (2012) 0.84

Reduction-triggered delivery using nucleoside-lipid based carriers possessing a cleavable PEG coating. J Control Release (2011) 0.83

Real time imaging of supramolecular assembly formation via programmed nucleolipid recognition. J Am Chem Soc (2008) 0.83

Staphylococcus aureus resistance on titanium coated with multivalent PEGylated-peptides. Biomaterials (2010) 0.83

Paclitaxel-loaded expansile nanoparticles in a multimodal treatment model of malignant mesothelioma. Ann Thorac Surg (2011) 0.83

A large-molecular-weight polyanion, synthesized via ring-opening metathesis polymerization, as a lubricant for human articular cartilage. J Am Chem Soc (2013) 0.83

A dendritic thioester hydrogel based on thiol-thioester exchange as a dissolvable sealant system for wound closure. Angew Chem Int Ed Engl (2013) 0.83

Anionic nucleotide--lipids for in vitro DNA transfection. Bioconjug Chem (2009) 0.83

Hydrogels as intracellular depots for drug delivery. Mol Pharm (2011) 0.83

MRT letter: Contrast-enhanced computed tomographic imaging of soft callus formation in fracture healing. Microsc Res Tech (2011) 0.82

Assessment of contrast-enhanced computed tomography for imaging of cartilage during fracture healing. J Orthop Res (2012) 0.82

Cationic nucleoside lipids derived from universal bases: A rational approach for siRNA transfection. Bioconjug Chem (2010) 0.82

Dendritic supramolecular assemblies for drug delivery. Chem Commun (Camb) (2005) 0.82

Acidic polysaccharide mimics via ring-opening metathesis polymerization. J Am Chem Soc (2010) 0.82

Enzymatic release of a surface-adsorbed RGD therapeutic from a cleavable peptide anchor. ChemMedChem (2008) 0.82

Self-assembled microspheres from f-block elements and nucleoamphiphiles. Chem Commun (Camb) (2006) 0.81

Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells. Chem Biol (2006) 0.81

Ease of synthesis, controllable sizes, and in vivo large-animal-lymph migration of polymeric nanoparticles. ChemMedChem (2010) 0.81

The convergent synthesis of poly(glycerol-succinic acid) dendritic macromolecules. Chemistry (2003) 0.80

Triggered drug release from superhydrophobic meshes using high-intensity focused ultrasound. Adv Healthc Mater (2013) 0.80

Prevention of local tumor growth with paclitaxel-loaded microspheres. J Thorac Cardiovasc Surg (2008) 0.79

Nanotechnology in thoracic surgery. Ann Thorac Surg (2010) 0.79

Bioactive stent surface coating that promotes endothelialization while preventing platelet adhesion. Biomacromolecules (2011) 0.79

Imparting superhydrophobicity to biodegradable poly(lactide-co-glycolide) electrospun meshes. Biomacromolecules (2014) 0.79

Novel tissue adhesives to secure laser in situ keratomileusis flaps. J Cataract Refract Surg (2005) 0.79