PubRank

Leopold Flohé

Author PubWeight™ 37.82‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Peroxiredoxins. Biol Chem 2002 3.61
2 Gene disruption discloses role of selenoprotein P in selenium delivery to target tissues. Biochem J 2003 2.30
3 Basic principles and emerging concepts in the redox control of transcription factors. Antioxid Redox Signal 2011 1.82
4 Catalytic mechanisms and specificities of glutathione peroxidases: variations of a basic scheme. Biochim Biophys Acta 2009 1.33
5 Trends in selenium biochemistry. Nat Prod Rep 2002 1.33
6 Multiple thioredoxin-mediated routes to detoxify hydroperoxides in Mycobacterium tuberculosis. Arch Biochem Biophys 2004 1.25
7 Kinetics of peroxiredoxins and their role in the decomposition of peroxynitrite. Subcell Biochem 2007 1.23
8 Validation of Trypanosoma brucei trypanothione synthetase as drug target. Free Radic Biol Med 2004 1.18
9 Complementary antioxidant defense by cytoplasmic and mitochondrial peroxiredoxins in Leishmania infantum. Free Radic Biol Med 2002 1.09
10 Trypanosoma brucei and Trypanosoma cruzi tryparedoxin peroxidases catalytically detoxify peroxynitrite via oxidation of fast reacting thiols. J Biol Chem 2004 1.08
11 The catalytic site of glutathione peroxidases. Antioxid Redox Signal 2008 1.07
12 Kinetics and redox-sensitive oligomerisation reveal negative subunit cooperativity in tryparedoxin peroxidase of Trypanosoma brucei brucei. Biol Chem 2003 1.04
13 Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase. Biol Reprod 2002 1.01
14 Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes. Biochem J 2007 1.01
15 Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants. J Biol Chem 2003 1.00
16 The thioredoxin specificity of Drosophila GPx: a paradigm for a peroxiredoxin-like mechanism of many glutathione peroxidases. J Mol Biol 2006 1.00
17 Is there a role of glutathione peroxidases in signaling and differentiation? Biofactors 2003 1.00
18 Peroxidase: a term of many meanings. Antioxid Redox Signal 2008 0.98
19 Trypanothione synthesis in crithidia revisited. J Biol Chem 2004 0.98
20 Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification. Free Radic Biol Med 2008 0.97
21 The thiol-based redox networks of pathogens: unexploited targets in the search for new drugs. Biofactors 2006 0.94
22 Specificity and kinetics of a mitochondrial peroxiredoxin of Leishmania infantum. Free Radic Biol Med 2002 0.92
23 Two linked genes of Leishmania infantum encode tryparedoxins localised to cytosol and mitochondrion. Mol Biochem Parasitol 2004 0.90
24 Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS. Biol Chem 2003 0.90
25 Biosynthesis of trypanothione in Trypanosoma brucei brucei. Biol Chem 2003 0.90
26 Structure of the inactive variant C60S of Mycobacterium tuberculosis thiol peroxidase. Acta Crystallogr D Biol Crystallogr 2006 0.90
27 The mycobacterial thioredoxin peroxidase can act as a one-cysteine peroxiredoxin. J Biol Chem 2006 0.89
28 Verification of the interaction of a tryparedoxin peroxidase with tryparedoxin by ESI-MS/MS. Biol Chem 2003 0.85
29 NMR studies of the interaction of tryparedoxin with redox-inactive substrate homologues. Biochemistry 2003 0.80
30 HNE and Further Lipid Peroxidation Products. Biofactors 2005 0.80
31 Molecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetase. PLoS One 2013 0.80
32 Phospholipid-hydroperoxide glutathione peroxidase in sperm. Methods Enzymol 2002 0.78
33 Enzymes of the thiol-dependent hydroperoxide metabolism in pathogens as potential drug targets. Biofactors 2003 0.77
34 Selenoproteins - biochemistry and clinical relevance. Biol Chem 2007 0.76
35 A fast virtual screening approach to identify structurally diverse inhibitors of trypanothione reductase. Bioorg Med Chem Lett 2011 0.76
36 Identification of M. tuberculosis thioredoxin reductase inhibitors based on high-throughput docking using constraints. J Med Chem 2013 0.75
37 1H, 15N and 13C resonance assignments and secondary structure of tryparedoxin-I from Crithidia fasciculata. J Biomol NMR 2002 0.75