Published in J Cereb Blood Flow Metab on January 11, 2006
Neuronal activity regulates the regional vulnerability to amyloid-β deposition. Nat Neurosci (2011) 5.40
The astrocyte odyssey. Prog Neurobiol (2008) 2.58
The contribution of blood lactate to brain energy metabolism in humans measured by dynamic 13C nuclear magnetic resonance spectroscopy. J Neurosci (2010) 2.42
Sweet sixteen for ANLS. J Cereb Blood Flow Metab (2011) 2.33
Metabolite concentrations in the anterior cingulate cortex predict high neuropathic pain impact after spinal cord injury. Pain (2012) 2.22
Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy. J Cereb Blood Flow Metab (2009) 1.85
Brain lactate metabolism: the discoveries and the controversies. J Cereb Blood Flow Metab (2011) 1.71
Energetics of neuronal signaling and fMRI activity. Proc Natl Acad Sci U S A (2007) 1.65
Cerebral blood flow response to functional activation. J Cereb Blood Flow Metab (2009) 1.60
Selective defect of in vivo glycolysis in early Huntington's disease striatum. Proc Natl Acad Sci U S A (2007) 1.57
Tightly coupled brain activity and cerebral ATP metabolic rate. Proc Natl Acad Sci U S A (2008) 1.53
High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio. Proc Natl Acad Sci U S A (2010) 1.52
Metabolic and hemodynamic events after changes in neuronal activity: current hypotheses, theoretical predictions and in vivo NMR experimental findings. J Cereb Blood Flow Metab (2008) 1.47
13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR Biomed (2011) 1.47
Oxidative phosphorylation, not glycolysis, powers presynaptic and postsynaptic mechanisms underlying brain information processing. J Neurosci (2012) 1.47
Nonlinear coupling between cerebral blood flow, oxygen consumption, and ATP production in human visual cortex. Proc Natl Acad Sci U S A (2010) 1.44
Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration. J Cereb Blood Flow Metab (2006) 1.38
A glycogen phosphorylase inhibitor selectively enhances local rates of glucose utilization in brain during sensory stimulation of conscious rats: implications for glycogen turnover. J Neurochem (2007) 1.37
Scaling of brain metabolism with a fixed energy budget per neuron: implications for neuronal activity, plasticity and evolution. PLoS One (2011) 1.36
Baseline brain energy supports the state of consciousness. Proc Natl Acad Sci U S A (2009) 1.35
In vivo 13C spectroscopy in the rat brain using hyperpolarized [1-(13)C]pyruvate and [2-(13)C]pyruvate. J Magn Reson (2010) 1.33
Astrocytes are poised for lactate trafficking and release from activated brain and for supply of glucose to neurons. J Neurochem (2009) 1.30
Stable isotope-resolved metabolomics and applications for drug development. Pharmacol Ther (2011) 1.29
A BOLD search for baseline. Neuroimage (2007) 1.26
Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions. Metabolomics (2010) 1.23
Oxidative neuroenergetics in event-related paradigms. J Neurosci (2009) 1.22
Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia. J Clin Invest (2013) 1.20
A coherent neurobiological framework for functional neuroimaging provided by a model integrating compartmentalized energy metabolism. Proc Natl Acad Sci U S A (2007) 1.18
Cortical energy demands of signaling and nonsignaling components in brain are conserved across mammalian species and activity levels. Proc Natl Acad Sci U S A (2013) 1.18
Posteromedial cortex glutamate and GABA predict intrinsic functional connectivity of the default mode network. Neuroimage (2012) 1.17
Methylglyoxal, the dark side of glycolysis. Front Neurosci (2015) 1.16
Predominant enhancement of glucose uptake in astrocytes versus neurons during activation of the somatosensory cortex. J Neurosci (2010) 1.16
Metabolic connectivity by interregional correlation analysis using statistical parametric mapping (SPM) and FDG brain PET; methodological development and patterns of metabolic connectivity in adults. Eur J Nucl Med Mol Imaging (2008) 1.15
¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism. Biol Psychiatry (2011) 1.14
Quantitative imaging of energy expenditure in human brain. Neuroimage (2012) 1.09
An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements. J Comput Neurosci (2009) 1.09
Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway. J Neuroinflammation (2010) 1.09
Deciphering neuron-glia compartmentalization in cortical energy metabolism. Front Neuroenergetics (2009) 1.08
New insights into central roles of cerebral oxygen metabolism in the resting and stimulus-evoked brain. J Cereb Blood Flow Metab (2008) 1.07
Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. Theor Biol Med Model (2007) 1.05
Glutamatergic function in the resting awake human brain is supported by uniformly high oxidative energy. J Cereb Blood Flow Metab (2013) 1.05
Fueling and imaging brain activation. ASN Neuro (2012) 1.04
Comment on recent modeling studies of astrocyte-neuron metabolic interactions. J Cereb Blood Flow Metab (2010) 1.02
Imaging brain activation: simple pictures of complex biology. Ann N Y Acad Sci (2008) 1.02
A longitudinal proton magnetic resonance spectroscopy study of mild traumatic brain injury. J Neurotrauma (2011) 1.02
Direct evidence for activity-dependent glucose phosphorylation in neurons with implications for the astrocyte-to-neuron lactate shuttle. Proc Natl Acad Sci U S A (2014) 1.01
Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons. Glia (2010) 1.00
Quantitative fMRI and oxidative neuroenergetics. Neuroimage (2012) 0.98
Glutamine and glutamate levels in children and adolescents with bipolar disorder: a 4.0-T proton magnetic resonance spectroscopy study of the anterior cingulate cortex. J Am Acad Child Adolesc Psychiatry (2007) 0.98
An enquiry into metabolite domains. Biophys J (2007) 0.98
Neuronal correlate of BOLD signal fluctuations at rest: err on the side of the baseline. Proc Natl Acad Sci U S A (2010) 0.97
Neurovascular and Neurometabolic Couplings in Dynamic Calibrated fMRI: Transient Oxidative Neuroenergetics for Block-Design and Event-Related Paradigms. Front Neuroenergetics (2010) 0.96
Neurophysiology of functional imaging. Neuroimage (2008) 0.96
Energy metabolism and inflammation in brain aging and Alzheimer's disease. Free Radic Biol Med (2016) 0.95
Advanced In Vivo Heteronuclear MRS Approaches for Studying Brain Bioenergetics Driven by Mitochondria. Methods Mol Biol (2009) 0.95
Measurement of cerebral oxidative glucose consumption in patients with type 1 diabetes mellitus and hypoglycemia unawareness using (13)C nuclear magnetic resonance spectroscopy. Metabolism (2009) 0.94
Astroglial pentose phosphate pathway rates in response to high-glucose environments. ASN Neuro (2012) 0.94
Astrocytic energetics during excitatory neurotransmission: What are contributions of glutamate oxidation and glycolysis? Neurochem Int (2013) 0.94
Cerebral oxygen demand for short-lived and steady-state events. J Neurochem (2009) 0.94
Astrocytes as the glucose shunt for glutamatergic neurons at high activity: an in silico study. J Neurophysiol (2008) 0.94
The micro-architecture of the cerebral cortex: functional neuroimaging models and metabolism. Neuroimage (2008) 0.93
Brain biochemical effects of methylphenidate treatment using proton magnetic spectroscopy in youth with attention-deficit hyperactivity disorder: a controlled pilot study. CNS Neurosci Ther (2010) 0.93
Tactile and non-tactile sensory paradigms for fMRI and neurophysiologic studies in rodents. Methods Mol Biol (2009) 0.93
Pitfalls in Fractal Time Series Analysis: fMRI BOLD as an Exemplary Case. Front Physiol (2012) 0.92
Labeled acetate as a marker of astrocytic metabolism. J Cereb Blood Flow Metab (2011) 0.92
In vivo proton MRS to quantify anesthetic effects of pentobarbital on cerebral metabolism and brain activity in rat. Magn Reson Med (2009) 0.92
Diabetes Mellitus, Obesity, and Diagnosis of Amyotrophic Lateral Sclerosis: A Population-Based Study. JAMA Neurol (2015) 0.91
Epilepsy, regulation of brain energy metabolism and neurotransmission. Curr Med Chem (2009) 0.91
A comprehensive metabolic profile of cultured astrocytes using isotopic transient metabolic flux analysis and C-labeled glucose. Front Neuroenergetics (2011) 0.90
A functional and structural investigation of the human fronto-basal volitional saccade network. PLoS One (2012) 0.90
Brain glutamine synthesis requires neuronal aspartate: a commentary. J Cereb Blood Flow Metab (2010) 0.89
The contribution of ketone bodies to basal and activity-dependent neuronal oxidation in vivo. J Cereb Blood Flow Metab (2014) 0.87
Static and Dynamic Intrinsic Connectivity following Mild Traumatic Brain Injury. J Neurotrauma (2015) 0.87
Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect. Front Physiol (2015) 0.87
Insights from neuroenergetics into the interpretation of functional neuroimaging: an alternative empirical model for studying the brain's support of behavior. J Cereb Blood Flow Metab (2014) 0.87
Transiently increased glutamate cycling in rat PFC is associated with rapid onset of antidepressant-like effects. Mol Psychiatry (2016) 0.86
Metabolic pathways and activity-dependent modulation of glutamate concentration in the human brain. Neurochem Res (2012) 0.86
Oxidative damage and amyloid-β metabolism in brain regions of the longest-lived rodents. J Neurosci Res (2013) 0.86
Astroglial networking contributes to neurometabolic coupling. Front Neuroenergetics (2013) 0.86
Metabolic Flux and Compartmentation Analysis in the Brain In vivo. Front Endocrinol (Lausanne) (2013) 0.85
Brain-derived neurotrophic factor enhances the expression of the monocarboxylate transporter 2 through translational activation in mouse cultured cortical neurons. J Cereb Blood Flow Metab (2009) 0.85
Evidence for the importance of measuring total brain activity in neuroimaging. Proc Natl Acad Sci U S A (2011) 0.84
Lack of effect of citalopram on magnetic resonance spectroscopy measures of glutamate and glutamine in frontal cortex of healthy volunteers. J Psychopharmacol (2009) 0.83
Rare copy number deletions predict individual variation in human brain metabolite concentrations in individuals with alcohol use disorders. Biol Psychiatry (2011) 0.83
Anterior thalamic lesions produce chronic and profuse transcriptional de-regulation in retrosplenial cortex: A model of retrosplenial hypoactivity and covert pathology. Thalamus Relat Syst (2008) 0.83
Glucose administration after traumatic brain injury improves cerebral metabolism and reduces secondary neuronal injury. Brain Res (2013) 0.83
Dynamic imaging of brain function. Methods Mol Biol (2009) 0.83
Mitochondrial calcium uptake capacity modulates neocortical excitability. J Cereb Blood Flow Metab (2013) 0.83
Energetics of inhibition: insights with a computational model of the human GABAergic neuron-astrocyte cellular complex. J Cereb Blood Flow Metab (2010) 0.82
Glutamatergic and GABAergic metabolism in mouse brain under chronic nicotine exposure: implications for addiction. PLoS One (2012) 0.82
General requirement for harvesting antennae at ca and h channels and transporters. Front Neuroenergetics (2010) 0.82
Quantitative in silico Analysis of Neurotransmitter Pathways Under Steady State Conditions. Front Endocrinol (Lausanne) (2013) 0.82
Functional neuroimaging: a physiological perspective. Front Neuroenergetics (2010) 0.81
A glia-neuron alanine/ammonium shuttle is central to energy metabolism in bee retina. J Physiol (2008) 0.81
GABA, resting-state connectivity and the developing brain. Neonatology (2014) 0.81
Brain alanine formation as an ammonia-scavenging pathway during hyperammonemia: effects of glutamine synthetase inhibition in rats and astrocyte-neuron co-cultures. J Cereb Blood Flow Metab (2013) 0.81
Pyruvate Dehydrogenase Kinases in the Nervous System: Their Principal Functions in Neuronal-glial Metabolic Interaction and Neuro-metabolic Disorders. Curr Neuropharmacol (2012) 0.80
Absent without leave; a neuroenergetic theory of mind wandering. Front Psychol (2013) 0.80
Role of ongoing, intrinsic activity of neuronal populations for quantitative neuroimaging of functional magnetic resonance imaging-based networks. Brain Connect (2011) 0.80
Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab (2007) 11.79
Mitochondrial dysfunction in the elderly: possible role in insulin resistance. Science (2003) 11.39
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A (2007) 3.76
Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. Arch Gen Psychiatry (2004) 3.64
Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients. Diabetes (2007) 2.91
Energetic basis of brain activity: implications for neuroimaging. Trends Neurosci (2004) 2.56
The contribution of blood lactate to brain energy metabolism in humans measured by dynamic 13C nuclear magnetic resonance spectroscopy. J Neurosci (2010) 2.42
Rapid calculations of susceptibility-induced magnetostatic field perturbations for in vivo magnetic resonance. Phys Med Biol (2006) 2.39
Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI. Proc Natl Acad Sci U S A (2002) 2.28
Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology (2006) 2.15
The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo. Proc Natl Acad Sci U S A (2005) 2.11
High magnetic field water and metabolite proton T1 and T2 relaxation in rat brain in vivo. Magn Reson Med (2006) 2.05
Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study. Arch Gen Psychiatry (2002) 2.01
Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors. Am J Psychiatry (2002) 1.99
Altered brain mitochondrial metabolism in healthy aging as assessed by in vivo magnetic resonance spectroscopy. J Cereb Blood Flow Metab (2009) 1.85
In vivo NMR studies of the glutamate neurotransmitter flux and neuroenergetics: implications for brain function. Annu Rev Physiol (2002) 1.79
Artefactual subcortical hyperperfusion in PET studies normalized to global mean: lessons from Parkinson's disease. Neuroimage (2008) 1.72
Cross-modal plasticity revealed by electrotactile stimulation of the tongue in the congenitally blind. Brain (2005) 1.69
Energetics of neuronal signaling and fMRI activity. Proc Natl Acad Sci U S A (2007) 1.65
Increased brain monocarboxylic acid transport and utilization in type 1 diabetes. Diabetes (2006) 1.65
Increased cortical GABA concentrations in depressed patients receiving ECT. Am J Psychiatry (2003) 1.64
In vivo 1H-[13C]-NMR spectroscopy of cerebral metabolism. NMR Biomed (2003) 1.64
Total neuroenergetics support localized brain activity: implications for the interpretation of fMRI. Proc Natl Acad Sci U S A (2002) 1.62
Simultaneous activation of mouse main and accessory olfactory bulbs by odors or pheromones. J Comp Neurol (2005) 1.55
Glutamate metabolism in major depressive disorder. Am J Psychiatry (2014) 1.52
Dynamic shim updating (DSU) for multislice signal acquisition. Magn Reson Med (2003) 1.51
Odor maps of aldehydes and esters revealed by functional MRI in the glomerular layer of the mouse olfactory bulb. Proc Natl Acad Sci U S A (2003) 1.48
13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR Biomed (2011) 1.47
Role of trehalose phosphate synthase in anoxia tolerance and development in Drosophila melanogaster. J Biol Chem (2001) 1.46
Magnetic field modeling with a set of individual localized coils. J Magn Reson (2010) 1.43
Magnetic resonance spectroscopy of neurotransmitters in human brain. Ann Neurol (2003) 1.41
Capillary-oxygenation-level-dependent near-infrared spectrometry in frontal lobe of humans. J Cereb Blood Flow Metab (2006) 1.39
Dynamic fMRI and EEG recordings during spike-wave seizures and generalized tonic-clonic seizures in WAG/Rij rats. J Cereb Blood Flow Metab (2004) 1.38
Dynamics of changes in blood flow, volume, and oxygenation: implications for dynamic functional magnetic resonance imaging calibration. J Cereb Blood Flow Metab (2006) 1.38
Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation. J Cereb Blood Flow Metab (2004) 1.38
Glutamate-glutamine cycling in the epileptic human hippocampus. Epilepsia (2002) 1.37
Baseline brain energy supports the state of consciousness. Proc Natl Acad Sci U S A (2009) 1.35
Clinical studies implementing glutamate neurotransmission in mood disorders. Ann N Y Acad Sci (2003) 1.35
Dynamic shim updating on the human brain. J Magn Reson (2006) 1.34
Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy. Biol Psychiatry (2005) 1.33
Regional glucose metabolism and glutamatergic neurotransmission in rat brain in vivo. Proc Natl Acad Sci U S A (2004) 1.32
Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals. Proc Natl Acad Sci U S A (2008) 1.30
To musicians, the message is in the meter pre-attentive neuronal responses to incongruent rhythm are left-lateralized in musicians. Neuroimage (2005) 1.30
Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET. Neuropsychopharmacology (2007) 1.30
Dynamic multi-coil shimming of the human brain at 7 T. J Magn Reson (2011) 1.29
Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia. J Clin Invest (2010) 1.27
A BOLD search for baseline. Neuroimage (2007) 1.26
A comparison of (13)C NMR measurements of the rates of glutamine synthesis and the tricarboxylic acid cycle during oral and intravenous administration of [1-(13)C]glucose. Brain Res Brain Res Protoc (2003) 1.26
Magnetic field homogenization of the human prefrontal cortex with a set of localized electrical coils. Magn Reson Med (2010) 1.23
Multicoil shimming of the mouse brain. Magn Reson Med (2011) 1.23
Neuronal and glial metabolite content of the epileptogenic human hippocampus. Ann Neurol (2002) 1.21
Lactate preserves neuronal metabolism and function following antecedent recurrent hypoglycemia. J Clin Invest (2013) 1.20
Impaired GABA neuronal response to acute benzodiazepine administration in panic disorder. Am J Psychiatry (2004) 1.20
Neurodevelopment of C57B/L6 mouse brain assessed by in vivo diffusion tensor imaging. NMR Biomed (2007) 1.20
Brain energy metabolism and blood flow differences in healthy aging. J Cereb Blood Flow Metab (2012) 1.20
State of the art direct 13C and indirect 1H-[13C] NMR spectroscopy in vivo. A practical guide. NMR Biomed (2011) 1.19
Cortical energy demands of signaling and nonsignaling components in brain are conserved across mammalian species and activity levels. Proc Natl Acad Sci U S A (2013) 1.18
Quantitative 1H NMR spectroscopy of blood plasma metabolites. Anal Chem (2003) 1.17
Biophysical basis of brain activity: implications for neuroimaging. Q Rev Biophys (2002) 1.17
Measurements of the anaplerotic rate in the human cerebral cortex using 13C magnetic resonance spectroscopy and [1-13C] and [2-13C] glucose. J Neurochem (2006) 1.17
Recurrent antecedent hypoglycemia alters neuronal oxidative metabolism in vivo. Diabetes (2009) 1.16
Evidence that GAD65 mediates increased GABA synthesis during intense neuronal activity in vivo. J Neurochem (2006) 1.15
Detection of [1,6-13C2]-glucose metabolism in rat brain by in vivo 1H-[13C]-NMR spectroscopy. Magn Reson Med (2003) 1.15
¹H-[¹³C]-nuclear magnetic resonance spectroscopy measures of ketamine's effect on amino acid neurotransmitter metabolism. Biol Psychiatry (2011) 1.14
Evaluation of cerebral acetate transport and metabolic rates in the rat brain in vivo using 1H-[13C]-NMR. J Cereb Blood Flow Metab (2010) 1.14
Dopamine release in ventral striatum during Iowa Gambling Task performance is associated with increased excitement levels in pathological gambling. Addiction (2010) 1.14
Is lactate a volume transmitter of metabolic states of the brain? Front Neuroenergetics (2012) 1.14
Cognitive control in auditory working memory is enhanced in musicians. PLoS One (2010) 1.13
In situ 3D magnetic resonance metabolic imaging of microwave-irradiated rodent brain: a new tool for metabolomics research. J Neurochem (2009) 1.13
Normalization in PET group comparison studies--the importance of a valid reference region. Neuroimage (2008) 1.12
Dynamic Shimming of the Human Brain at 7 Tesla. Concepts Magn Reson Part B Magn Reson Eng (2010) 1.11
Mapping at glomerular resolution: fMRI of rat olfactory bulb. Magn Reson Med (2002) 1.11
In vivo GABA editing using a novel doubly selective multiple quantum filter. Magn Reson Med (2002) 1.10