Published in J Mol Med (Berl) on January 17, 2006
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Pleiotropic effects of neutrophils on myocyte apoptosis and left ventricular remodeling during early volume overload. J Mol Cell Cardiol (2009) 0.91
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The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80
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The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2014). Hypertens Res (2014) 4.83
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Endothelial cell senescence in human atherosclerosis: role of telomere in endothelial dysfunction. Circulation (2002) 4.12
Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci U S A (2006) 3.54
Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. J Biol Chem (2003) 3.41
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol (2004) 3.03
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A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med (2009) 2.65
G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med (2005) 2.64
TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity. Nature (2006) 2.56
Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway. Proc Natl Acad Sci U S A (2010) 2.53
Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle. Nat Med (2004) 2.52
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Critical roles of muscle-secreted angiogenic factors in therapeutic neovascularization. Circ Res (2006) 2.31
Roles of cardiac transcription factors in cardiac hypertrophy. Circ Res (2003) 2.31
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J Biol Chem (2005) 2.26
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis. Science (2009) 2.23
Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction. Circ J (2012) 2.15
Peroxisome proliferator-activated receptor gamma plays a critical role in inhibition of cardiac hypertrophy in vitro and in vivo. Circulation (2002) 2.12
Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res (2010) 2.12
Mesothelium contributes to vascular smooth muscle and mesenchyme during lung development. Proc Natl Acad Sci U S A (2008) 2.08
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IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. Nature (2008) 1.77
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol (2012) 1.75
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Bradykinin-induced microglial migration mediated by B1-bradykinin receptors depends on Ca2+ influx via reverse-mode activity of the Na+/Ca2+ exchanger. J Neurosci (2007) 1.74
Pathophysiology of myocardial reperfusion injury: preconditioning, postconditioning, and translational aspects of protective measures. Am J Physiol Heart Circ Physiol (2011) 1.73
Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy (2010) 1.70
Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice. J Clin Invest (2009) 1.69
Local coronary flow is associated with an unsuccessful complete block line at the mitral isthmus in patients with atrial fibrillation. Circ Arrhythm Electrophysiol (2011) 1.69
Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res (2006) 1.68
Ras induces vascular smooth muscle cell senescence and inflammation in human atherosclerosis. Circulation (2003) 1.67
Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy. Circ Res (2006) 1.66
Deletion of progranulin exacerbates atherosclerosis in ApoE knockout mice. Cardiovasc Res (2013) 1.64
Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overload. Circulation (2010) 1.63
Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes. Cell (2012) 1.60
Increased urine aquaporin-2 relative to plasma arginine vasopressin is a novel marker of response to tolvaptan in patients with decompensated heart failure. Circ J (2014) 1.55
Feasibility and safety of granulocyte colony-stimulating factor treatment in patients with acute myocardial infarction. Int J Cardiol (2006) 1.52
Low cardiac output stimulates vasopressin release in patients with stage d heart failure. Circ J (2014) 1.50
Endovascular aortic repair increases vascular stiffness and alters cardiac structure and function. Circ J (2013) 1.49
Introduction of point-of-care testing in Japanese outpatient clinics is associated with improvement in time in therapeutic range in anticoagulant-treated patients. Circ J (2014) 1.49
Prognostic significance of cystatin C in patients with ST-elevation myocardial infarction. Circ J (2009) 1.48
Elevated serum heart-type fatty acid-binding protein in the convalescent stage predicts long-term outcome in patients surviving acute myocardial infarction. Circ J (2012) 1.48
Retracted Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial. Hypertens Res (2010) 1.47
Differences in body temperature variability between subjects with and without diabetes and predictive value for cardiovascular events. Circ J (2013) 1.47
Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling. Circ Res (2005) 1.46
N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. Genes Dev (2009) 1.45
Restrictive left ventricular filling pattern does not result from increased left atrial pressure alone. Circulation (2008) 1.45
Angiotensin II type 1a receptor is involved in cell infiltration, cytokine production, and neovascularization in infarcted myocardium. Arterioscler Thromb Vasc Biol (2004) 1.45
Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway. Circulation (2006) 1.44
Protective role of SIRT1 in diabetic vascular dysfunction. Arterioscler Thromb Vasc Biol (2009) 1.43
Cardiac transcription factor Csx/Nkx2-5: Its role in cardiac development and diseases. Pharmacol Ther (2005) 1.42
Activation of MTK1/MEKK4 induces cardiomyocyte death and heart failure. J Mol Cell Cardiol (2009) 1.42
Endothelial Gab1 deletion accelerates angiotensin II-dependent vascular inflammation and atherosclerosis in apolipoprotein E knockout mice. Circ J (2012) 1.41
Regeneration of the Cardiac Conduction System by Adipose Tissue-Derived Stem Cells. Circ J (2015) 1.41
Conformational switch of angiotensin II type 1 receptor underlying mechanical stress-induced activation. EMBO Rep (2008) 1.40
Oxidative stress-induced signal transduction pathways in cardiac myocytes: involvement of ROS in heart diseases. Antioxid Redox Signal (2003) 1.40
Prognostic impact of left ventricular noncompaction in patients with Duchenne/Becker muscular dystrophy--prospective multicenter cohort study. Int J Cardiol (2013) 1.40
Endonasal endoscopic transsphenoidal chiasmapexy with silicone plates for empty sella syndrome: technical note. Neurol Med Chir (Tokyo) (2005) 1.39
An EP4 Receptor Agonist Inhibits Cardiac Fibrosis Through Activation of PKA Signaling in Hypertrophied Heart. Int Heart J (2016) 1.39
Inverse Correlation Between Calcium Accumulation and the Expansion Rate of Abdominal Aortic Aneurysms. Circ J (2015) 1.38
Molecular mechanism underlying inverse agonist of angiotensin II type 1 receptor. J Biol Chem (2006) 1.38
APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes. J Biol Chem (2002) 1.34
Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents. J Clin Invest (2010) 1.34
Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling. Hypertension (2002) 1.34
Self-referential processing of negative stimuli within the ventral anterior cingulate gyrus and right amygdala. Brain Cogn (2008) 1.33
Rostral anterior cingulate cortex activity mediates the relationship between the depressive symptoms and the medial prefrontal cortex activity. J Affect Disord (2009) 1.32
Diphtheria toxin-induced autophagic cardiomyocyte death plays a pathogenic role in mouse model of heart failure. J Biol Chem (2004) 1.31
Long-term outcome of therapeutic neovascularization using peripheral blood mononuclear cells for limb ischemia. Circ Cardiovasc Interv (2009) 1.30
Chronic doxorubicin cardiotoxicity is mediated by oxidative DNA damage-ATM-p53-apoptosis pathway and attenuated by pitavastatin through the inhibition of Rac1 activity. J Mol Cell Cardiol (2009) 1.28
Integrins play a critical role in mechanical stress-induced p38 MAPK activation. Hypertension (2002) 1.27
Central fatigue: the serotonin hypothesis and beyond. Sports Med (2006) 1.26
Cardiomyocytes fuse with surrounding noncardiomyocytes and reenter the cell cycle. J Cell Biol (2004) 1.26
Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins. J Biol Chem (2002) 1.26
UTF1 is a chromatin-associated protein involved in ES cell differentiation. J Cell Biol (2007) 1.24
Cytokine therapy prevents left ventricular remodeling and dysfunction after myocardial infarction through neovascularization. FASEB J (2004) 1.23
Generation of reelin-positive marginal zone cells from the caudomedial wall of telencephalic vesicles. J Neurosci (2004) 1.23