Published in Mol Cell on January 20, 2006
Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10. Hum Mol Genet (2007) 2.61
The structure and function of small nucleolar ribonucleoproteins. Nucleic Acids Res (2007) 2.50
Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita. Proc Natl Acad Sci U S A (2008) 2.37
Human diseases of telomerase dysfunction: insights into tissue aging. Nucleic Acids Res (2007) 2.34
Proteostatic control of telomerase function through TRiC-mediated folding of TCAB1. Cell (2014) 1.82
Dyskeratosis congenita, stem cells and telomeres. Biochim Biophys Acta (2009) 1.62
Physiological assembly and activity of human telomerase complexes. Mech Ageing Dev (2007) 1.56
Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface. J Mol Biol (2011) 1.53
The genetics of dyskeratosis congenita. Cancer Genet (2011) 1.50
SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs. RNA (2009) 1.41
Dyskeratosis congenita. FEBS Lett (2010) 1.36
The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification. J Biol Chem (2009) 1.21
RNA pseudouridylation: new insights into an old modification. Trends Biochem Sci (2013) 1.20
H/ACA small nucleolar RNA pseudouridylation pockets bind substrate RNA to form three-way junctions that position the target U for modification. Proc Natl Acad Sci U S A (2007) 1.19
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA. Nat Struct Mol Biol (2009) 1.17
How U38, 39, and 40 of many tRNAs become the targets for pseudouridylation by TruA. Mol Cell (2007) 1.15
Formation of the conserved pseudouridine at position 55 in archaeal tRNA. Nucleic Acids Res (2006) 1.15
Nucleolar stress with and without p53. Nucleus (2014) 1.13
Hierarchical recruitment into nascent ribosomes of assembly factors required for 27SB pre-rRNA processing in Saccharomyces cerevisiae. Nucleic Acids Res (2012) 1.09
Interactions among Ytm1, Erb1, and Nop7 required for assembly of the Nop7-subcomplex in yeast preribosomes. Mol Biol Cell (2008) 1.09
Reconstitution and structural analysis of the yeast box H/ACA RNA-guided pseudouridine synthase. Genes Dev (2011) 1.08
How a single protein complex accommodates many different H/ACA RNAs. Trends Biochem Sci (2006) 1.06
Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance. Mol Cell Biol (2008) 1.06
Combined in silico and experimental identification of the Pyrococcus abyssi H/ACA sRNAs and their target sites in ribosomal RNAs. Nucleic Acids Res (2008) 1.04
Unraveling the pathogenesis of Hoyeraal-Hreidarsson syndrome, a complex telomere biology disorder. Br J Haematol (2015) 1.01
Dynamic association and localization of human H/ACA RNP proteins. RNA (2006) 1.01
H/ACA small RNA dysfunctions in disease reveal key roles for noncoding RNA modifications in hematopoietic stem cell differentiation. Cell Rep (2013) 1.01
Identification of determinants in the protein partners aCBF5 and aNOP10 necessary for the tRNA:Psi55-synthase and RNA-guided RNA:Psi-synthase activities. Nucleic Acids Res (2007) 0.99
Unveiling substrate RNA binding to H/ACA RNPs: one side fits all. Curr Opin Struct Biol (2008) 0.97
Pathogenic NAP57 mutations decrease ribonucleoprotein assembly in dyskeratosis congenita. Hum Mol Genet (2009) 0.95
Trypanosoma brucei spliced leader RNA maturation by the cap 1 2'-O-ribose methyltransferase and SLA1 H/ACA snoRNA pseudouridine synthase complex. Mol Cell Biol (2008) 0.95
Evolutionary history of selenocysteine incorporation from the perspective of SECIS binding proteins. BMC Evol Biol (2009) 0.94
A conserved deubiquitinating enzyme controls cell growth by regulating RNA polymerase I stability. Cell Rep (2012) 0.92
Long-distance placement of substrate RNA by H/ACA proteins. RNA (2008) 0.91
Pseudouridines in spliceosomal snRNAs. Protein Cell (2011) 0.88
Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment. Aging Cell (2011) 0.87
Structural characterization of the ribosome maturation protein, RimM. J Bacteriol (2007) 0.87
The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic. Genes Dev (2011) 0.87
Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies. Curr Pharmacogenomics Person Med (2010) 0.87
RNA-guided isomerization of uridine to pseudouridine--pseudouridylation. RNA Biol (2014) 0.87
Structures of ribonucleoprotein particle modification enzymes. Q Rev Biophys (2010) 0.86
Analysis of the binding of the N-terminal conserved domain of yeast Cbf5p to a box H/ACA snoRNA. RNA (2006) 0.86
Different mechanisms for pseudouridine formation in yeast 5S and 5.8S rRNAs. Mol Cell Biol (2008) 0.84
Functional and structural impact of target uridine substitutions on the H/ACA ribonucleoprotein particle pseudouridine synthase. Biochemistry (2010) 0.84
Ribosome assembly factors Pwp1 and Nop12 are important for folding of 5.8S rRNA during ribosome biogenesis in Saccharomyces cerevisiae. Mol Cell Biol (2014) 0.84
Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease. Wiley Interdiscip Rev RNA (2014) 0.83
Archaeal proteins Nop10 and Gar1 increase the catalytic activity of Cbf5 in pseudouridylating tRNA. Sci Rep (2012) 0.83
The coding/non-coding overlapping architecture of the gene encoding the Drosophila pseudouridine synthase. BMC Mol Biol (2007) 0.82
Variable expression of Dkc1 mutations in mice. Genesis (2009) 0.81
Structural and functional evidence of high specificity of Cbf5 for ACA trinucleotide. RNA (2010) 0.80
Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients. PLoS One (2015) 0.80
Ribonucleoproteins in archaeal pre-rRNA processing and modification. Archaea (2013) 0.79
Insight into the Protein Components of the Box H/ACA RNP. Curr Proteomics (2008) 0.79
Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations. Biochemistry (2009) 0.78
Accurate placement of substrate RNA by Gar1 in H/ACA RNA-guided pseudouridylation. Nucleic Acids Res (2015) 0.77
Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus. Proteins (2012) 0.77
Comparative study of two box H/ACA ribonucleoprotein pseudouridine-synthases: relation between conformational dynamics of the guide RNA, enzyme assembly and activity. PLoS One (2013) 0.77
Kinetic and thermodynamic characterization of the reaction pathway of box H/ACA RNA-guided pseudouridine formation. Nucleic Acids Res (2012) 0.77
Differential requirements for H/ACA ribonucleoprotein components in cell proliferation and response to DNA damage. Histochem Cell Biol (2015) 0.76
Progress in Human and Tetrahymena Telomerase Structure. Annu Rev Biophys (2017) 0.76
Inhibition of human dyskerin as a new approach to target ribosome biogenesis. PLoS One (2014) 0.75
Human intron-encoded AluACA RNAs and telomerase RNA share a common element promoting RNA accumulation. RNA Biol (2016) 0.75
Structure-function relationships of archaeal Cbf5 during in vivo RNA-guided pseudouridylation. RNA (2016) 0.75
Revisiting the structure/function relationships of H/ACA(-like) RNAs: a unified model for Euryarchaea and Crenarchaea. Nucleic Acids Res (2015) 0.75
RNA-guided RNA cleavage by a CRISPR RNA-Cas protein complex. Cell (2009) 11.12
Regulation of cellular metabolism by protein lysine acetylation. Science (2010) 10.55
CRISPR-based adaptive immune systems. Curr Opin Microbiol (2011) 8.07
Cas6 is an endoribonuclease that generates guide RNAs for invader defense in prokaryotes. Genes Dev (2008) 7.09
Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science (2010) 6.04
Functional profiling of a human cytomegalovirus genome. Proc Natl Acad Sci U S A (2003) 5.21
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs. Nat Rev Mol Cell Biol (2007) 4.91
Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. Cancer Cell (2009) 4.47
Prokaryotic silencing (psi)RNAs in Pyrococcus furiosus. RNA (2008) 4.46
Essential features and rational design of CRISPR RNAs that function with the Cas RAMP module complex to cleave RNAs. Mol Cell (2012) 3.96
Interaction of the Cas6 riboendonuclease with CRISPR RNAs: recognition and cleavage. Structure (2011) 3.58
Single-layer MoS2 phototransistors. ACS Nano (2011) 3.43
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science (2009) 3.34
A universal method to produce low-work function electrodes for organic electronics. Science (2012) 3.33
The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev (2004) 3.29
Effects of metformin versus glipizide on cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease. Diabetes Care (2012) 2.84
Mechanism of activity-dependent downregulation of the neuron-specific K-Cl cotransporter KCC2. J Neurosci (2004) 2.76
Binding and cleavage of CRISPR RNA by Cas6. RNA (2010) 2.67
Identification of a KCNE2 gain-of-function mutation in patients with familial atrial fibrillation. Am J Hum Genet (2004) 2.66
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ Res (2010) 2.65
Modeling desertification change in Minqin County, China. Environ Monit Assess (2005) 2.56
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun (2005) 2.55
Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells. Kidney Int (2004) 2.55
Structure and function of archaeal box C/D sRNP core proteins. Nat Struct Biol (2003) 2.55
A redox-dependent pathway for regulating class II HDACs and cardiac hypertrophy. Cell (2008) 2.47
Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes. Nat Immunol (2002) 2.46
Pharmacological inhibition of AMP-activated protein kinase provides neuroprotection in stroke. J Biol Chem (2005) 2.44
Reference values for continuous glucose monitoring in Chinese subjects. Diabetes Care (2009) 2.41
BDNF-induced TrkB activation down-regulates the K+-Cl- cotransporter KCC2 and impairs neuronal Cl- extrusion. J Cell Biol (2002) 2.40
TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo. Mol Cell Biol (2010) 2.39
Efficient formulation of the stochastic simulation algorithm for chemically reacting systems. J Chem Phys (2004) 2.36
A new class of Solvent-in-Salt electrolyte for high-energy rechargeable metallic lithium batteries. Nat Commun (2013) 2.33
Charge order driven by Fermi-arc instability in Bi2Sr(2-x)La(x)CuO(6+δ). Science (2013) 2.31
The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens. Nat Immunol (2003) 2.26
Cell cycle-regulated trafficking of human telomerase to telomeres. Mol Biol Cell (2005) 2.26
Slc26a11, a chloride transporter, localizes with the vacuolar H(+)-ATPase of A-intercalated cells of the kidney. Kidney Int (2011) 2.21
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone. Nat Protoc (2010) 2.20
Telomerase RNA accumulates in Cajal bodies in human cancer cells. Mol Biol Cell (2003) 2.14
Molecular basis of box C/D RNA-protein interactions; cocrystal structure of archaeal L7Ae and a box C/D RNA. Structure (2004) 2.08
Subtype-selective antagonists of lysophosphatidic Acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques. Circulation (2003) 2.07
Small nucleolar RNAs: versatile trans-acting molecules of ancient evolutionary origin. Gene Expr (2002) 2.06
Oncogenic ERBB3 mutations in human cancers. Cancer Cell (2013) 2.06
Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell (2007) 2.03
Woltjer-Taylor state without Taylor's conjecture: plasma relaxation at all wavelengths. Phys Rev Lett (2012) 1.98
Structure of the Cmr2 subunit of the CRISPR-Cas RNA silencing complex. Structure (2012) 1.97
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med (2013) 1.93
Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. J Clin Invest (2005) 1.90
Distinctive patterns of gene expression in premalignant gastric mucosa and gastric cancer. Cancer Res (2003) 1.88
Health risks of limited-contact water recreation. Environ Health Perspect (2011) 1.86
Lysophosphatidic acid induces neointima formation through PPARgamma activation. J Exp Med (2004) 1.86
RNA-guided RNA modification: functional organization of the archaeal H/ACA RNP. Genes Dev (2005) 1.86
Bis(2-dimethylamino-1,10-phenanthroline-κN,N')bis-(thio-cyanato-κN)nickel(II) methanol disolvate. Acta Crystallogr Sect E Struct Rep Online (2008) 1.86
Structure of an RNA silencing complex of the CRISPR-Cas immune system. Mol Cell (2013) 1.82
Using peripheral blood mononuclear cells to determine a gene expression profile of acute ischemic stroke: a pilot investigation. Circulation (2005) 1.79
Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J (2004) 1.79
Spatial variability of shallow groundwater level, electrical conductivity and nitrate concentration, and risk assessment of nitrate contamination in North China Plain. Environ Int (2005) 1.78
Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress. Immunity (2004) 1.76
ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties. Mol Pharmacol (2006) 1.76
Longitudinal association of vitamin B-6, folate, and vitamin B-12 with depressive symptoms among older adults over time. Am J Clin Nutr (2010) 1.74
Platelet-derived growth factor production by B16 melanoma cells leads to increased pericyte abundance in tumors and an associated increase in tumor growth rate. Cancer Res (2004) 1.72
RNA recognition and cleavage by a splicing endonuclease. Science (2006) 1.70
Fabrication of single- and multilayer MoS2 film-based field-effect transistors for sensing NO at room temperature. Small (2011) 1.69
Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter. Mol Pharmacol (2008) 1.69
The complex exogenous RNA spectra in human plasma: an interface with human gut biota? PLoS One (2012) 1.68
Diffusion tensor imaging of Parkinson's disease, atypical parkinsonism, and essential tremor. Mov Disord (2013) 1.68
Ultrasound-guided establishment of hip arthroscopy portals. Arthroscopy (2009) 1.67
Adherence to a Mediterranean-type dietary pattern and cognitive decline in a community population. Am J Clin Nutr (2010) 1.67
Paracrine signaling by platelet-derived growth factor-CC promotes tumor growth by recruitment of cancer-associated fibroblasts. Cancer Res (2009) 1.65
Prevalence and evolution of drug resistance HIV-1 variants in Henan, China. Cell Res (2005) 1.64
Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome. J Clin Invest (2002) 1.64
Porous Li4 Ti5 O12 coated with N-doped carbon from ionic liquids for Li-ion batteries. Adv Mater (2011) 1.63
Kaposi's sarcoma-associated herpesvirus lytic origin (ori-Lyt)-dependent DNA replication: identification of the ori-Lyt and association of K8 bZip protein with the origin. J Virol (2003) 1.63
Somatodendritic accumulation of misfolded SOD1-L126Z in motor neurons mediates degeneration: alphaB-crystallin modulates aggregation. Hum Mol Genet (2005) 1.63
Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome. Proc Natl Acad Sci U S A (2006) 1.63
The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice. J Cell Biol (2010) 1.61
Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets. Cell Transplant (2009) 1.60
Geoclimatic influences on invasive aspergillosis after hematopoietic stem cell transplantation. Clin Infect Dis (2010) 1.58
A new linearized Crank-Nicolson mixed element scheme for the extended Fisher-Kolmogorov equation. ScientificWorldJournal (2013) 1.58
Transcription factor AtMYB103 is required for anther development by regulating tapetum development, callose dissolution and exine formation in Arabidopsis. Plant J (2007) 1.58
Identification of a Kir3.4 mutation in congenital long QT syndrome. Am J Hum Genet (2010) 1.57
Genome-wide association analyses in Han Chinese identify two new susceptibility loci for amyotrophic lateral sclerosis. Nat Genet (2013) 1.57
SNP-SNP interactions in breast cancer susceptibility. BMC Cancer (2006) 1.56