Published in RNA on October 29, 2008
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Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence. PLoS One (2011) 1.04
Massive activation of archaeal defense genes during viral infection. J Virol (2013) 1.03
Mouse genome engineering via CRISPR-Cas9 for study of immune function. Immunity (2015) 1.02
The three major types of CRISPR-Cas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus. Mol Microbiol (2014) 1.02
Essential requirements for the detection and degradation of invaders by the Haloferax volcanii CRISPR/Cas system I-B. RNA Biol (2013) 1.01
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Three CRISPR-Cas immune effector complexes coexist in Pyrococcus furiosus. RNA (2015) 0.86
Bipartite recognition of target RNAs activates DNA cleavage by the Type III-B CRISPR-Cas system. Genes Dev (2016) 0.86
CRISPR-Cas systems preferentially target the leading regions of MOBF conjugative plasmids. RNA Biol (2013) 0.86
DNase H Activity of Neisseria meningitidis Cas9. Mol Cell (2015) 0.85
Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complex. Nucleic Acids Res (2014) 0.85
The CRISPR RNA-guided surveillance complex in Escherichia coli accommodates extended RNA spacers. Nucleic Acids Res (2016) 0.84
Comparative analysis ofCas6b processing and CRISPR RNA stability. RNA Biol (2013) 0.83
Identification and characterization of small RNAs in the hyperthermophilic archaeon Sulfolobus solfataricus. PLoS One (2012) 0.82
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Whole genome sequencing reveals a novel CRISPR system in industrial Clostridium acetobutylicum. J Ind Microbiol Biotechnol (2014) 0.77
A mutant ('lab strain') of the hyperthermophilic archaeon Pyrococcus furiosus, lacking flagella, has unusual growth physiology. Extremophiles (2014) 0.76
Requirements for Pseudomonas aeruginosa Type I-F CRISPR-Cas Adaptation Determined Using a Biofilm Enrichment Assay. J Bacteriol (2016) 0.75
Molecular determinants for CRISPR RNA maturation in the Cas10-Csm complex and roles for non-Cas nucleases. Nucleic Acids Res (2017) 0.75
Knowledge-based discovery for designing CRISPR-CAS systems against invading mobilomes in thermophiles. Syst Synth Biol (2015) 0.75
A lentivirus-free inducible CRISPR-Cas9 system for efficient targeting of human genes. Anal Biochem (2017) 0.75
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CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies. Microbiology (2005) 9.83
The Piwi-piRNA pathway provides an adaptive defense in the transposon arms race. Science (2007) 9.36
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A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis. Science (2009) 3.34
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TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo. Mol Cell Biol (2010) 2.39
Cell cycle-regulated trafficking of human telomerase to telomeres. Mol Biol Cell (2005) 2.26
Telomerase RNA accumulates in Cajal bodies in human cancer cells. Mol Biol Cell (2003) 2.14
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Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation. Mol Cell (2007) 2.03
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An H/ACA guide RNA directs U2 pseudouridylation at two different sites in the branchpoint recognition region in Xenopus oocytes. RNA (2002) 1.37
Processive and distributive extension of human telomeres by telomerase under homeostatic and nonequilibrium conditions. Mol Cell (2011) 1.26
The nucleolar localization domain of the catalytic subunit of human telomerase. J Biol Chem (2002) 1.24
Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells. Mol Biol Cell (2008) 1.22
Structural basis for substrate placement by an archaeal box C/D ribonucleoprotein particle. Mol Cell (2010) 1.18
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Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex. Nat Struct Mol Biol (2007) 1.16
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Determinants of the interaction of the spinal muscular atrophy disease protein SMN with the dimethylarginine-modified box H/ACA small nucleolar ribonucleoprotein GAR1. J Biol Chem (2002) 1.09
Sequences spanning the leader-repeat junction mediate CRISPR adaptation to phage in Streptococcus thermophilus. Nucleic Acids Res (2015) 1.03
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Visualization of human telomerase localization by fluorescence microscopy techniques. Methods Mol Biol (2011) 0.96
Programmable plasmid interference by the CRISPR-Cas system in Thermococcus kodakarensis. RNA Biol (2013) 0.96
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Archaeal guide RNAs function in rRNA modification in the eukaryotic nucleus. Curr Biol (2002) 0.93
A Cajal body-independent pathway for telomerase trafficking in mice. Exp Cell Res (2010) 0.91
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