|
1
|
Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter.
|
Biochemistry
|
2005
|
2.27
|
|
2
|
Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoter.
|
J Am Chem Soc
|
2006
|
1.93
|
|
3
|
Identification and characterization of nucleolin as a c-myc G-quadruplex-binding protein.
|
J Biol Chem
|
2009
|
1.72
|
|
4
|
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4.
|
Nucleic Acids Res
|
2007
|
1.66
|
|
5
|
Formation of pseudosymmetrical G-quadruplex and i-motif structures in the proximal promoter region of the RET oncogene.
|
J Am Chem Soc
|
2007
|
1.53
|
|
6
|
Design and synthesis of an expanded porphyrin that has selectivity for the c-MYC G-quadruplex structure.
|
J Am Chem Soc
|
2005
|
1.40
|
|
7
|
NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression but does not cleave the nuclease hypersensitive element III(1).
|
Mol Cancer Ther
|
2009
|
1.19
|
|
8
|
Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor gene.
|
Nucleic Acids Res
|
2008
|
1.16
|
|
9
|
Heterogeneous nuclear ribonucleoprotein K and nucleolin as transcriptional activators of the vascular endothelial growth factor promoter through interaction with secondary DNA structures.
|
Biochemistry
|
2011
|
1.03
|
|
10
|
Characterization of DNA damage induced by a natural product antitumor antibiotic leinamycin in human cancer cells.
|
Chem Res Toxicol
|
2010
|
1.00
|
|
11
|
Binding of G-quadruplex-interactive agents to distinct G-quadruplexes induces different biological effects in MiaPaCa cells.
|
Nucleosides Nucleotides Nucleic Acids
|
2005
|
0.89
|
|
12
|
Cellular response and molecular mechanism of antitumor activity by leinamycin in MiaPaCa human pancreatic cancer cells.
|
Anticancer Drugs
|
2004
|
0.86
|
|
13
|
Synthesis and characterization of a small analogue of the anticancer natural product leinamycin.
|
Bioorg Med Chem
|
2012
|
0.81
|
|
14
|
DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences.
|
Bioorg Med Chem
|
2012
|
0.80
|
|
15
|
The macrocycle of leinamycin imparts hydrolytic stability to the thiol-sensing 1,2-dithiolan-3-one 1-oxide unit of the natural product.
|
Bioorg Med Chem Lett
|
2012
|
0.79
|
|
16
|
Thiol-dependent DNA cleavage by aminomethylated Beaucage's reagent.
|
Org Biomol Chem
|
2010
|
0.77
|