PubRank

M Perricaudet

Author PubWeight™ 202.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses. Nature 1979 6.60
2 Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo. Science 1991 6.28
3 The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA. Cell 1980 5.80
4 Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat Med 1999 4.92
5 Widespread long-term gene transfer to mouse skeletal muscles and heart. J Clin Invest 1992 4.43
6 A spliced Epstein-Barr virus gene expressed in immortalized lymphocytes is created by circularization of the linear viral genome. EMBO J 1988 3.69
7 Epstein-Barr virus gene expression in P3HR1-superinfected Raji cells. J Virol 1987 3.56
8 Spliced RNA from the IR1-U2 region of Epstein-Barr virus: presence of an open reading frame for a repetitive polypeptide. EMBO J 1984 3.12
9 A promoter for the highly spliced EBNA family of RNAs of Epstein-Barr virus. J Virol 1987 3.10
10 Evaluation of the transfer and expression in mice of an enzyme-encoding gene using a human adenovirus vector. Hum Gene Ther 1990 3.04
11 Epstein-Barr virus mRNAs produced by alternative splicing. Nucleic Acids Res 1986 2.94
12 Two interferon mRNAs in human fibroblasts: in vitro translation and Escherichia coli cloning studies. Proc Natl Acad Sci U S A 1980 2.88
13 An Epstein-Barr virus transcription unit is at least 84 kilobases long. Nucleic Acids Res 1986 2.83
14 An adenovirus vector for gene transfer into neurons and glia in the brain. Science 1993 2.79
15 Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice. Nature 1993 2.73
16 Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses. Nat Genet 1993 2.67
17 Individual products of the adenovirus 12S and 13S EIa mRNAs stimulate viral EIIa and EIII expression at the transcriptional level. Proc Natl Acad Sci U S A 1984 2.64
18 Adenovirus-mediated in vivo gene transfer and expression in normal rat liver. Nat Genet 1992 2.63
19 Structure of two adenovirus type 12 transforming polypeptides and their evolutionary implications. Nature 1980 2.38
20 In vitro and in vivo synthesis of the hepatitis B virus surface antigen and of the receptor for polymerized human serum albumin from recombinant human adenoviruses. EMBO J 1985 2.18
21 Recombinational construction in Escherichia coli of infectious adenoviral genomes. Proc Natl Acad Sci U S A 1997 2.10
22 The E4 transcriptional unit of Ad2: far upstream sequences are required for its transactivation by E1A. Nucleic Acids Res 1984 2.02
23 Transfer of a foreign gene into the brain using adenovirus vectors. Nat Genet 1993 1.95
24 mRNAs from human adenovirus 2 early region 4. J Virol 1984 1.92
25 Adenovirus vectors for gene delivery. Curr Opin Biotechnol 1999 1.89
26 A recombinant E1-deleted canine adenoviral vector capable of transduction and expression of a transgene in human-derived cells and in vivo. Hum Gene Ther 1997 1.82
27 Epstein-Barr virus EBNA3A and EBNA3C proteins both repress RBP-J kappa-EBNA2-activated transcription by inhibiting the binding of RBP-J kappa to DNA. J Virol 1996 1.71
28 Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells. Proc Natl Acad Sci U S A 1992 1.62
29 Mapping of the gene coding for Epstein-Barr virus-determined nuclear antigen EBNA3 and its transient overexpression in a human cell line by using an adenovirus expression vector. J Virol 1987 1.61
30 Efficient dual transcomplementation of adenovirus E1 and E4 regions from a 293-derived cell line expressing a minimal E4 functional unit. J Virol 1996 1.50
31 The Epstein-Barr virus determined nuclear antigens EBNA-3A, -3B, and -3C repress EBNA-2-mediated transactivation of the viral terminal protein 1 gene promoter. Virology 1994 1.43
32 Adenoviral SERCA1a gene transfer to adult rat ventricular myocytes induces physiological changes in calcium handling. Cardiovasc Res 2001 1.43
33 Adenovirus-mediated transfer of the thyroid sodium/iodide symporter gene into tumors for a targeted radiotherapy. Cancer Res 2000 1.43
34 Angiostatin gene transfer: inhibition of tumor growth in vivo by blockage of endothelial cell proliferation associated with a mitosis arrest. Proc Natl Acad Sci U S A 1998 1.37
35 RGD inclusion in the hexon monomer provides adenovirus type 5-based vectors with a fiber knob-independent pathway for infection. J Virol 1999 1.37
36 BRCA1 and BRCA2 are necessary for the transcription-coupled repair of the oxidative 8-oxoguanine lesion in human cells. Cancer Res 2000 1.36
37 Diversity of airway epithelial cell targets for in vivo recombinant adenovirus-mediated gene transfer. J Clin Invest 1993 1.35
38 The sequence of the 3' non-coding region of the hexon mRNA discloses a novel adenovirus gene. Nucleic Acids Res 1981 1.31
39 Construction of restriction enzyme fragment libraries containing DNA from human adenovirus types 2 and 5. Gene 1980 1.29
40 Predicted structure of two adenovirus tumor antigens. Proc Natl Acad Sci U S A 1980 1.27
41 Long-term correction of mouse dystrophic degeneration by adenovirus-mediated transfer of a minidystrophin gene. Nat Genet 1993 1.27
42 Long-term gene delivery into the livers of immunocompetent mice with E1/E4-defective adenoviruses. J Virol 1997 1.23
43 Polyadenylic acid addition sites in the adenovirus type 2 major late transcription unit. J Virol 1983 1.22
44 Receptors bound to antiprogestin from abortive complexes with hormone responsive elements. Nature 1988 1.21
45 Expression mechanism of the hepatitis B virus (HBV) C gene and biosynthesis of HBe antigen. Virology 1989 1.21
46 Full-length and truncated versions of the hepatitis B virus (HBV) X protein (pX) transactivate the cmyc protooncogene at the transcriptional level. Biochem Biophys Res Commun 1991 1.20
47 Down-regulation of vascular endothelial growth factor by tissue inhibitor of metalloproteinase-2: effect on in vivo mammary tumor growth and angiogenesis. Cancer Res 2001 1.18
48 Advances in adenoviral vectors: from genetic engineering to their biology. FASEB J 1997 1.18
49 The E4 promoter of adenovirus type 2 contains an E1A dependent cis-acting element. Nucleic Acids Res 1986 1.18
50 Adenovirus and adeno-associated virus mediated gene transfer. Br Med Bull 1995 1.17
51 In vivo adenovirus-mediated gene transfer into ocular tissues. Gene Ther 1994 1.14
52 Structure of three spliced mRNAs from region E3 of adenovirus type 2. Gene 1983 1.13
53 Defective bacteriophage lambda chromosome, potential vector for DNA fragments obtained after cleavage by Bacillus amyloliquefaciens endonuclease (BamI). FEBS Lett 1975 1.11
54 Detection of anti-Epstein-Barr-virus transactivator (ZEBRA) antibodies in sera from patients with nasopharyngeal carcinoma. Int J Cancer 1991 1.11
55 Adenovirus-mediated delivery of a uPA/uPAR antagonist suppresses angiogenesis-dependent tumor growth and dissemination in mice. Gene Ther 1998 1.10
56 Recombinant adenoviruses as vaccines. Biologicals 1995 1.10
57 Gamma-rays-induced death of human cells carrying mutations of BRCA1 or BRCA2. Oncogene 1999 1.07
58 Combined effects of radiotherapy and angiostatin gene therapy in glioma tumor model. Proc Natl Acad Sci U S A 2000 1.06
59 Phase I study of a recombinant adenovirus-mediated gene transfer in lung cancer patients. J Natl Cancer Inst 1996 1.06
60 Efficient adenovirus-mediated gene transfer into human blood monocyte-derived macrophages. Biochem Biophys Res Commun 1993 1.06
61 Construction of a defective adenovirus vector expressing the pseudorabies virus glycoprotein gp50 and its use as a live vaccine. J Gen Virol 1990 1.06
62 Functional protection of dystrophic mouse (mdx) muscles after adenovirus-mediated transfer of a dystrophin minigene. Proc Natl Acad Sci U S A 1996 1.04
63 AdTIMP-2 inhibits tumor growth, angiogenesis, and metastasis, and prolongs survival in mice. Hum Gene Ther 2001 1.03
64 Prevention of bleomycin-induced pulmonary fibrosis after adenovirus-mediated transfer of the bacterial bleomycin resistance gene. J Clin Invest 1997 1.02
65 Adenoviral-mediated gene transfer to renal tubular cells in vivo. Kidney Int 1994 1.02
66 Adenoviral vectors as functional retrograde neuronal tracers. Brain Res 1994 0.99
67 Propagation in E. coli of bacteriophage lambda with integrated fragments of adenovirus 2 DNA. Gene 1976 0.99
68 Highly efficient adenovirus-mediated gene transfer to cardiac myocytes after single-pass coronary delivery. Hum Gene Ther 2000 0.99
69 Novel downstream elements upregulate transcription initiated from an Epstein-Barr virus latent promoter. EMBO J 1991 0.98
70 Transplantation to the rat brain of human neural progenitors that were genetically modified using adenoviruses. Nat Genet 1995 0.98
71 The constitutive expression of the immunomodulatory gp19k protein in E1-, E3- adenoviral vectors strongly reduces the host cytotoxic T cell response against the vector. Gene Ther 1995 0.97
72 Gene therapy using adenovirus vectors. Curr Top Microbiol Immunol 1995 0.97
73 Genetic manipulations of adenovirus type 5 fiber resulting in liver tropism attenuation. Gene Ther 2003 0.96
74 Adenoviral vector as a gene delivery system into cultured rat neuronal and glial cells. Eur J Neurosci 1993 0.96
75 Dynamic assessment of antiangiogenic therapy by monitoring both tumoral vascularization and tissue degeneration. Gene Ther 2006 0.95
76 Direct intracerebral gene transfer of an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease. Neuroreport 1994 0.95
77 Expression of human alpha 1-antitrypsin using a recombinant adenovirus vector. FEBS Lett 1990 0.94
78 Bacteriophage lambda and plasmid vectors, allowing fusion of cloned genes in each of the three translational phases. Nucleic Acids Res 1978 0.94
79 Low-efficiency of percutaneous adenovirus-mediated arterial gene transfer in the atherosclerotic rabbit. J Clin Invest 1995 0.94
80 cDNA cloning and transient expression of the Epstein-Barr virus-determined nuclear antigen EBNA3B in human cells and identification of novel transcripts from its coding region. J Virol 1990 0.94
81 Hepatitis B virus (HBV) X gene expression in human cells and anti-HBx antibodies detection in chronic HBV infection. Virology 1990 0.93
82 LacZ gene transfer into tumor cells abrogates tumorigenicity and protects mice against the development of further tumors. Gene Ther 1996 0.93
83 Arterial gene transfer to rabbit endothelial and smooth muscle cells using percutaneous delivery of an adenoviral vector. Circulation 1994 0.93
84 Description and properties of bacteriophage lambda vectors useful for the cloning of EcoRI DNA fragments. Biochimie 1978 0.92
85 Bacterial cloning of the rabbit uteroglobin structural gene. Biochem Biophys Res Commun 1980 0.92
86 Replication-defective recombinant adenovirus expressing the Epstein-Barr virus (EBV) envelope glycoprotein gp340/220 induces protective immunity against EBV-induced lymphomas in the cottontop tamarin. J Gen Virol 1993 0.91
87 Efficient, repeated adenovirus-mediated gene transfer in mice lacking both tumor necrosis factor alpha and lymphotoxin alpha. J Virol 1998 0.91
88 BRCA1 carries tumor suppressor activity distinct from that of p53 and p21. Cancer Gene Ther 2001 0.89
89 In vitro and in vivo hepatoma cell-specific expression of a gene transferred with an adenoviral vector. Hum Gene Ther 1996 0.89
90 Different mRNAs from the transforming region of highly oncogenic and non-oncogenic human adenoviruses. Nature 1982 0.88
91 The soluble fragment of VE-cadherin inhibits angiogenesis by reducing endothelial cell proliferation and tube capillary formation. Cancer Gene Ther 2010 0.88
92 Respective roles of TNF-alpha and IL-6 in the immune response-elicited by adenovirus-mediated gene transfer in mice. Gene Ther 2006 0.88
93 Gene transfer to human fetal pulmonary tissue developed in immunodeficient SCID mice. Hum Gene Ther 1994 0.87
94 Clustered alternative splice sites in Epstein-Barr virus RNAs. Nucleic Acids Res 1987 0.87
95 Activation of HIV-specific ribozyme activity by self-cleavage. Nucleic Acids Res 1993 0.87
96 Lung gene therapy: in vivo adenovirus-mediated gene transfer to rhesus monkey airway epithelium. Hum Gene Ther 1994 0.86
97 Detection of anti-Epstein-Barr virus trans-activator (ZEBRA) antibodies in sera from patients with human immunodeficiency virus. J Infect Dis 1991 0.86
98 Stable transduction of actively dividing cells via a novel adenoviral/episomal vector. Mol Ther 2000 0.86
99 Excision and recombination of adenovirus DNA fragments in Escherichia coli. Science 1977 0.85
100 In vivo adenovirus-mediated transfer of human CFTR cDNA to rhesus monkey airway epithelium: efficacy, toxicity and safety. Gene Ther 1994 0.84
101 Transcriptional activation by the E1A regions of adenovirus types 40 and 41. Virology 1987 0.84
102 Adenoviral interleukin-2 gene transfer into P815 tumor cells abrogates tumorigenicity and induces antitumoral immunity in mice. Hum Gene Ther 1993 0.84
103 Identification of a short amino acid sequence essential for efficient nuclear targeting of the Epstein-Barr virus nuclear antigen 3A. J Virol 1993 0.84
104 Active specific T-cell-based immunotherapy for cancer: nucleic acids, peptides, whole native proteins, recombinant viruses, with dendritic cell adjuvants or whole tumor cell-based vaccines. Principles and future prospects. Cytokines Cell Mol Ther 1998 0.84
105 CFTR gene transfer corrects defective glycoconjugate secretion in human CF epithelial tracheal cells. Am J Physiol 1995 0.83
106 In vivo adenovirus-mediated delivery of a uPA/uPAR antagonist reduces retinal neovascularization in a mouse model of retinopathy. Gene Ther 2003 0.83
107 Heart-specific targeting of beta-galactosidase by the ventricle-specific cardiac myosin light chain 2 promoter using adenovirus vectors. Hum Gene Ther 1998 0.83
108 Improved efficiency of arterial gene transfer by use of poloxamer 407 as a vehicle for adenoviral vectors. Gene Ther 1997 0.83
109 Complete recovery of mice from a pre-established tumor by direct intratumoral delivery of an adenovirus vector harboring the murine IL-2 gene. Gene Ther 1995 0.83
110 Phenotypic alteration of astrocytes induced by ciliary neurotrophic factor in the intact adult brain, As revealed by adenovirus-mediated gene transfer. J Neurosci 1997 0.83
111 Analysis of cloned mRNA sequences from the transforming region of adenovirus 2. Cold Spring Harb Symp Quant Biol 1980 0.83
112 Adenovirus mediated gene transfer in organotypic brain slices. Neurobiol Dis 1995 0.82
113 Purification of RNA-DNA hybrids by exclusion chromatography. J Biol Chem 1979 0.82
114 Mechanism of adenovirus improvement of cationic liposome-mediated gene transfer. Biochim Biophys Acta 1997 0.82
115 Erythropoietin gene transfer and expression in adult normal mice: use of an adenovirus vector. Hum Gene Ther 1994 0.82
116 Defective and nondefective adenovirus vectors for expressing foreign genes in vitro and in vivo. Gene 1991 0.82
117 The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers. Gene Ther 2006 0.82
118 The role of IL-6 in the inflammatory and humoral response to adenoviral vectors. J Gene Med 2000 0.82
119 Polarity of secretion of alpha 1-antitrypsin by human respiratory epithelial cells after adenoviral transfer of a human alpha 1-antitrypsin cDNA. Am J Respir Cell Mol Biol 1995 0.82
120 Systemic delivery of antiangiogenic adenovirus AdmATF induces liver resistance to metastasis and prolongs survival of mice. Hum Gene Ther 1999 0.82
121 High frequency of specific CD8+ T cells in the tumor and blood is associated with efficient local IL-12 gene therapy of cancer. J Immunol 1999 0.81
122 IL-2 gene delivery within an established murine tumor causes its regression without proliferation of preexisting antitumor-specific CTL. J Immunol 1997 0.81
123 Adenovirus-mediated gene transfer in canine eyes: a preclinical study for gene therapy of human uveal melanoma. J Gene Med 2001 0.80
124 Angiogenesis induced in muscle by a recombinant adenovirus expressing functional isoforms of basic fibroblast growth factor. Gene Ther 1999 0.80
125 Induction of a cytolytic T-cell response in mice with a recombinant adenovirus coding for tumor antigen P815A. Int J Cancer 1996 0.80
126 The messenger RNAs from the transforming region of human adenoviruses. Curr Top Microbiol Immunol 1984 0.80
127 Adenovirus-mediated gene transfer in dog prostate: a preclinical study of a relevant model system for gene therapy of human prostatic cancer. Prostate Cancer Prostatic Dis 1999 0.80
128 A gene transfer comparative study of HSA-conjugated antiangiogenic factors in a transgenic mouse model of metastatic ocular cancer. Cancer Gene Ther 2006 0.79
129 Full kringles of plasminogen (aa 1-566) mediate complete regression of human MDA-MB-231 breast tumor xenografted in nude mice. Gene Ther 2005 0.79
130 Efficient delivery of angiostatin K1-5 into tumors following insertion of an NGR peptide into adenovirus capsid. Gene Ther 2009 0.79
131 Strategies for cancer gene therapy using adenoviral vectors. J Mol Med (Berl) 1996 0.79
132 A novel method using baculovirus-mediated gene transfer for production of recombinant adeno-associated virus vectors. J Gen Virol 2001 0.78
133 Adenoviral gene delivery. Methods Cell Biol 1997 0.78
134 Heart muscle-specific gene expression using replication defective recombinant adenovirus. Gene Ther 1996 0.78
135 Complete characterization of the gene coding for the Epstein-Barr virus major membrane antigen gp 220/340 and selective expression of a secreted form of gp 220. Biochem Biophys Res Commun 1989 0.78
136 Reduction of restenosis after angioplasty in an atheromatous rabbit model by suicide gene therapy. Circulation 1997 0.78
137 Gene therapy of rat C6 glioma using adenovirus-mediated transfer of the herpes simplex virus thymidine kinase gene: long-term follow-up by magnetic resonance imaging. Gene Ther 1996 0.78
138 Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritis. Gene Ther 2002 0.78
139 The identification of new transcription elements active in Epstein-Barr virus latent gene expression. C R Acad Sci III 1991 0.78
140 Robust functional gene validation by adenoviral vectors: one-step Escherichia coli-derived recombinant adenoviral genome construction. Gene Ther 2004 0.77
141 Differential toxicity of ganciclovir for rat neurons and astrocytes in primary culture following adenovirus-mediated transfer of the HSVtk gene. Gene Ther 1997 0.77
142 Keratinocytes as a target for gene therapy. Sustained production of erythropoietin in mice by human keratinocytes transduced with an adenoassociated virus vector. Arch Dermatol 1996 0.77
143 Feasibility of adenovirus-mediated gene transfer in vivo. Bone Marrow Transplant 1992 0.76
144 Restoration of hexosaminidase A activity in human Tay-Sachs fibroblasts via adenoviral vector-mediated gene transfer. Gene Ther 1996 0.76
145 Expression of rubella virus cDNA encoding the E1 structural protein. Biochimie 1989 0.76
146 [Development of adenoviral vectors in gene therapy: application to gene transfer in muscles]. C R Seances Soc Biol Fil 1996 0.76
147 Induction of cytolytic T lymphocytes by immunization of mice with an adenovirus containing a mouse homolog of the human MAGE-A genes. Cancer Immunol Immunother 2001 0.76
148 Canstatin gene electrotransfer combined with radiotherapy: preclinical trials for cancer treatment. Gene Ther 2008 0.76
149 Integration of viral sequences into the c-myc gene in two mammary adenocarcinomas induced by polyomavirus in athymic nude mice. J Virol 1995 0.76
150 The use of adenovirus vectors for intracerebral grafting of transfected nervous cells. Neuroreport 1994 0.75
151 Enhancement of humoral immunity to SIVenv following simultaneous inoculation of mice by three recombinant adenoviruses encoding SIVenv/poliovirus chimeras, Tat and Rev. AIDS Res Hum Retroviruses 1997 0.75
152 The analysis of EBV proteins which are antigenic in vivo. Nucleic Acids Res 1988 0.75
153 [Construction of derivatives of bacteriophage lambdaplac5 vectors permitting the placement of foreign genes under the control of lactose operon promotor of Escherichia Coli (proceedings)]. Ann Microbiol (Paris) 1979 0.75
154 Third-generation adenovectors for gene therapy. Restor Neurol Neurosci 1995 0.75
155 Using adenoviral vectors to transfer the CNTF gene into the CNS. Restor Neurol Neurosci 1995 0.75
156 Regulated expression of Epstein-Barr virus nuclear antigen 3-encoding gene carried on stable episomal vectors in human cells. Gene 1990 0.75
157 Dynamics of gene transfer to retinal pigment epithelium. Invest Ophthalmol Vis Sci 1996 0.75
158 Degenerated pIX-IVa2 adenoviral vector sequences lowers reacquisition of the E1 genes during virus amplification in 293 cells. Gene Ther 2001 0.75
159 Expression from cardiomyocyte-specific promoter after adenovirus-mediated gene transfer in vitro and in vivo. C R Acad Sci III 1997 0.75
160 Adenovirus mediated gene transfer to the central nervous system. Gene Ther 1994 0.75
161 Transgene amplification and persistence after delivery of retroviral vector and packaging functions with E1/E4-deleted adenoviruses. Cancer Gene Ther 2000 0.75
162 Adenoviral vectors. Mol Cell Biol Hum Dis Ser 1995 0.75
163 Adenovirus vector-transduced hepatocytes implanted via a preformed collagen/PTFE support persist for at least 4 weeks in vivo. Gene Ther 1996 0.75
164 [Molecular biology of the transforming region of human type 5 adenovirus]. Biochimie 1983 0.75
165 An abinitio quantum-mechanical investigation on the rotational isomerism in amides and esters. Int J Pept Protein Res 1973 0.75
166 Organoids direct systemic expression of erythropoietin in mice. Gene Ther 1995 0.75
167 [Gene transfer with a therapeutic purpose in the central nervous system]. Nouv Rev Fr Hematol 1993 0.75
168 Adenovirus-mediated gene transfer of a human IL-6 antagonist. Gene Ther 1997 0.75
169 Identification of recombinant plasmids containing DNA sequences derived from the 3' end of ovine thyroglobulin mRNA. Mol Biol Rep 1982 0.75
170 The two core sequences of the adenovirus E1A inducible E4 promoter are required for the formation of a specific DNA-protein complex. Biochem Biophys Res Commun 1989 0.75
171 Transplantation of cells genetically modified and direct intracerebral gene transfer with an adenoviral vector expressing tyrosine hydroxylase in a rat model of Parkinson's disease. Restor Neurol Neurosci 1995 0.75
172 Residual expression of reporter genes in constructs mimicking HIV genome organization. Res Virol 1995 0.75
173 Systemic administration of a recombinant adenovirus encoding a HSA-Angiostatin kringle 1-3 conjugate inhibits MDA-MB-231 tumor growth and metastasis in a transgenic model of spontaneous eye cancer. Mol Ther 2003 0.75
174 Repression of the viral latent promoter BC-R2 in Epstein-Barr virus negative cell lines. Biochem Biophys Res Commun 1992 0.75