PubRank

David R Beier

Author PubWeight™ 75.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PRDM16 controls a brown fat/skeletal muscle switch. Nature 2008 13.08
2 Agouti C57BL/6N embryonic stem cells for mouse genetic resources. Nat Methods 2009 3.68
3 Efficient generation and mapping of recessive developmental mutations using ENU mutagenesis. Nat Genet 2002 2.30
4 Utilization of a whole genome SNP panel for efficient genetic mapping in the mouse. Genome Res 2006 2.26
5 Cystin, a novel cilia-associated protein, is disrupted in the cpk mouse model of polycystic kidney disease. J Clin Invest 2002 2.07
6 A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish. Development 2002 2.00
7 NEK8 links the ATR-regulated replication stress response and S phase CDK activity to renal ciliopathies. Mol Cell 2013 1.97
8 Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice. J Biol Chem 2002 1.87
9 Lethal skeletal dysplasia in mice and humans lacking the golgin GMAP-210. N Engl J Med 2010 1.81
10 Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease. J Am Soc Nephrol 2006 1.78
11 Nek8 regulates the expression and localization of polycystin-1 and polycystin-2. J Am Soc Nephrol 2008 1.70
12 Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet 2005 1.69
13 Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest 2009 1.67
14 Mutation mapping and identification by whole-genome sequencing. Genome Res 2012 1.51
15 Prdm16 is required for normal palatogenesis in mice. Hum Mol Genet 2009 1.46
16 Cordon-bleu is a conserved gene involved in neural tube formation. Dev Biol 2003 1.44
17 Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia. Cytoskeleton (Hoboken) 2010 1.32
18 TAT-mediated PRDX6 protein transduction protects against eye lens epithelial cell death and delays lens opacity. Am J Physiol Cell Physiol 2008 1.27
19 Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope. J Biol Chem 2011 1.23
20 Confirmation and high resolution mapping of an atherosclerosis susceptibility gene in mice on Chromosome 1. Mamm Genome 2002 1.16
21 The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proc Natl Acad Sci U S A 2010 1.15
22 Interacting genetic loci cause airway hyperresponsiveness. Physiol Genomics 2005 1.15
23 Gene structure and functional analysis of the mouse nidogen-2 gene: nidogen-2 is not essential for basement membrane formation in mice. Mol Cell Biol 2002 1.12
24 Gata4 is necessary for normal pulmonary lobar development. Am J Respir Cell Mol Biol 2006 1.09
25 A defect in a novel ADAMTS family member is the cause of the belted white-spotting mutation. Development 2003 1.06
26 Using ENU mutagenesis for phenotype-driven analysis of the mouse. Methods Enzymol 2010 1.01
27 Loss of the ciliary kinase Nek8 causes left-right asymmetry defects. J Am Soc Nephrol 2013 0.97
28 A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype. Neural Dev 2011 0.97
29 Defects in ciliary localization of Nek8 is associated with cystogenesis. Pediatr Nephrol 2008 0.96
30 A mutation in NFkB interacting protein 1 results in cardiomyopathy and abnormal skin development in wa3 mice. Hum Mol Genet 2005 0.96
31 Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease. Acta Neuropathol Commun 2015 0.94
32 Genome-wide identification of mouse congenital heart disease loci. Hum Mol Genet 2010 0.94
33 SNP2RFLP: a computational tool to facilitate genetic mapping using benchtop analysis of SNPs. Mamm Genome 2008 0.93
34 Magnetic resonance imaging assessment of a murine model of recessive polycystic kidney disease. Comp Med 2002 0.91
35 The naive airway hyperresponsiveness of the A/J mouse is Kit-mediated. Proc Natl Acad Sci U S A 2011 0.88
36 Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis. J Neurosci 2009 0.85
37 A mouse mutation in the 12R-lipoxygenase, Alox12b, disrupts formation of the epidermal permeability barrier. J Invest Dermatol 2007 0.85
38 Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo. PLoS Genet 2011 0.84
39 A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development. PLoS One 2010 0.83
40 ENU mutagenesis in mice identifies candidate genes for hypogonadism. Mamm Genome 2012 0.82
41 Mutation of the BiP/GRP78 gene causes axon outgrowth and fasciculation defects in the thalamocortical connections of the mammalian forebrain. J Comp Neurol 2013 0.82
42 An N-ethyl-N-nitrosourea mutagenesis recessive screen identifies two candidate regions for murine cardiomyopathy that map to chromosomes 1 and 15. Mamm Genome 2009 0.82
43 Description and genetic mapping of Polypodia: an X-linked dominant mouse mutant with ectopic caudal limbs and other malformations. Mamm Genome 2006 0.81
44 A mouse model of Waardenburg syndrome type IV resulting from an ENU-induced mutation in endothelin 3. Pigment Cell Res 2007 0.80
45 Comparative analysis of the mouse and human genes (Matn2 and MATN2) for matrilin-2, a filament-forming protein widely distributed in extracellular matrices. Matrix Biol 2002 0.80
46 De novo exon duplication in a new allele of mouse Glra1 (spasmodic). Genetics 2006 0.79
47 Debt91, a putative zinc finger protein differentially expressed during epithelial morphogenesis. Biochem Biophys Res Commun 2003 0.77
48 A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One 2012 0.77
49 Production of a natural antibody to the mouse polyoma virus is a multigenic trait. G3 (Bethesda) 2012 0.75
50 Three loci on mouse chromosome 5 and 10 modulate sex determination in XX Ods/+ mice. Genesis 2007 0.75
51 ENU mutagenesis: a work in progress. Physiol Genomics 2002 0.75