Published in Mol Cell Proteomics on February 07, 2006
Epithelial cell adhesion molecule: more than a carcinoma marker and adhesion molecule. Am J Pathol (2007) 2.78
The inhibition of tumor cell intravasation and subsequent metastasis via regulation of in vivo tumor cell motility by the tetraspanin CD151. Cancer Cell (2008) 2.27
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics (2009) 2.08
CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. J Virol (2008) 1.62
Laminin-binding integrins and their tetraspanin partners as potential antimetastatic targets. Expert Rev Mol Med (2010) 1.30
Suppression of mRNAs encoding tegument tetraspanins from Schistosoma mansoni results in impaired tegument turnover. PLoS Pathog (2010) 1.26
The role of protease activity in ErbB biology. Exp Cell Res (2008) 1.20
Gag induces the coalescence of clustered lipid rafts and tetraspanin-enriched microdomains at HIV-1 assembly sites on the plasma membrane. J Virol (2011) 1.18
Epithelial cell adhesion molecule (EpCAM) complex proteins promote transcription factor-mediated pluripotency reprogramming. J Biol Chem (2011) 1.11
Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain. PLoS Pathog (2008) 1.05
Cell surface and secreted protein profiles of human thyroid cancer cell lines reveal distinct glycoprotein patterns. J Proteome Res (2009) 0.99
Tetraspanins and tumor progression. Clin Exp Metastasis (2010) 0.98
CD9-positive microvesicles mediate the transfer of molecules to Bovine Spermatozoa during epididymal maturation. PLoS One (2013) 0.98
Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion. Br J Cancer (2010) 0.97
Gene array and fluorescence in situ hybridization biomarkers of activity of saracatinib (AZD0530), a Src inhibitor, in a preclinical model of colorectal cancer. Clin Cancer Res (2010) 0.96
ADAM and ADAMTS family proteins and their role in the colorectal cancer etiopathogenesis. BMB Rep (2013) 0.95
Effect of an anti-human Co-029/tspan8 mouse monoclonal antibody on tumor growth in a nude mouse model. Front Physiol (2014) 0.93
EpCAM proteolysis: new fragments with distinct functions? Biosci Rep (2013) 0.91
Cell surface markers in colorectal cancer prognosis. Int J Mol Sci (2010) 0.90
Glioblastoma inhibition by cell surface immunoglobulin protein EWI-2, in vitro and in vivo. Neoplasia (2009) 0.90
Expression and function of CD9 in melanoma cells. Mol Carcinog (2010) 0.89
Profiling of the tetraspanin CD151 web and conspiracy of CD151/integrin β1 complex in the progression of hepatocellular carcinoma. PLoS One (2011) 0.89
The tetraspanins CD9 and CD81 regulate CD9P1-induced effects on cell migration. PLoS One (2010) 0.88
Novel function of CD81 in controlling hepatitis C virus replication. J Virol (2010) 0.84
Cooperative role for tetraspanins in adhesin-mediated attachment of bacterial species to human epithelial cells. Infect Immun (2011) 0.82
CD26 expression on T-anaplastic large cell lymphoma (ALCL) line Karpas 299 is associated with increased expression of versican and MT1-MMP and enhanced adhesion. BMC Cancer (2013) 0.81
EWI-2 negatively regulates TGF-β signaling leading to altered melanoma growth and metastasis. Cell Res (2015) 0.81
Separation of biological proteins by liquid chromatography. Saudi Pharm J (2010) 0.81
The C-terminal tail of tetraspanin protein CD9 contributes to its function and molecular organization. J Cell Sci (2011) 0.81
Tetraspanins as therapeutic targets in hematological malignancy: a concise review. Front Physiol (2015) 0.81
CD9 negatively regulates CD26 expression and inhibits CD26-mediated enhancement of invasive potential of malignant mesothelioma cells. PLoS One (2014) 0.79
Novel CD9-targeted therapies in gastric cancer. World J Gastroenterol (2015) 0.79
Genome-wide association study of IgA nephropathy using 23 465 microsatellite markers in a Japanese population. J Hum Genet (2015) 0.79
CD151-A Striking Marker for Cancer Therapy. Biomark Cancer (2015) 0.78
Kidney Diseases Enhance Expression of Tetraspanin-8: A Possible Protective Effect against Tubular Injury. Nephron Extra (2014) 0.77
The FBI1/Akirin2 target gene, BCAM, acts as a suppressive oncogene. PLoS One (2013) 0.77
Pancreatic cancer stem cell markers and exosomes - the incentive push. World J Gastroenterol (2016) 0.76
IgSF8: a developmentally and functionally regulated cell adhesion molecule in olfactory sensory neuron axons and synapses. Mol Cell Neurosci (2012) 0.76
A large-scale RNAi screen identifies LCMR1 as a critical regulator of Tspan8-mediated melanoma invasion. Oncogene (2016) 0.76
Colocalisation of CD9 and mortalin in CD9-induced mitotic catastrophe in human prostate cancer cells. Br J Cancer (2007) 0.76
CUB domain containing protein 1 (CDCP1) modulates adhesion and motility in colon cancer cells. BMC Cancer (2014) 0.76
CD9 Expression in Colorectal Carcinomas and Its Prognostic Significance. J Pathol Transl Med (2016) 0.75
TETRASPANINs in Plants. Front Plant Sci (2017) 0.75
Tspan2: a tetraspanin protein involved in oligodendrogenesis and cancer metastasis. Biochem Soc Trans (2017) 0.75
p53 targets TSPAN8 to prevent invasion in melanoma cells. Oncogenesis (2017) 0.75
Multi-factorial modulation of colorectal carcinoma cells motility - partial coordination by the tetraspanin Co-029/tspan8. Oncotarget (2017) 0.75
Novel impact of EWI-2, CD9, and CD81 on TGF-β signaling in melanoma. Mol Cell Oncol (2015) 0.75
Proteomics-Based Analysis of Protein Complexes in Pluripotent Stem Cells and Cancer Biology. Int J Mol Sci (2016) 0.75
Tetraspanin 8 is a novel regulator of ILK-driven β1 integrin adhesion and signaling in invasive melanoma cells. Oncotarget (2017) 0.75
Oleic Acid Uptake Reveals the Rescued Enterocyte Phenotype of Colon Cancer Caco-2 by HT29-MTX Cells in Co-Culture Mode. Int J Mol Sci (2017) 0.75
Deficiency in Sperm-Egg Protein Interaction as a Major Cause of Fertilization Failure. J Membr Biol (2017) 0.75
KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res (2006) 13.98
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol (2008) 10.29
Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation. Blood (2012) 3.96
High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses. Blood (2012) 3.44
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med (2011) 3.03
Foamy macrophages from tuberculous patients' granulomas constitute a nutrient-rich reservoir for M. tuberculosis persistence. PLoS Pathog (2008) 3.02
Attenuated immunochemotherapy regimen (R-miniCHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial. Lancet Oncol (2011) 2.97
A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites. J Biol Chem (2003) 2.84
Discontinuation of imatinib in patients with advanced gastrointestinal stromal tumours after 3 years of treatment: an open-label multicentre randomised phase 3 trial. Lancet Oncol (2010) 2.74
Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity. Nat Med (2002) 2.46
Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects. J Clin Invest (2004) 2.40
Lateral organization of membrane proteins: tetraspanins spin their web. Biochem J (2009) 2.30
Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Blood (2008) 2.12
Outcome of treatment in adults with acute lymphoblastic leukemia: analysis of the LALA-94 trial. J Clin Oncol (2004) 2.11
A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem J (2006) 1.92
The CD81 partner EWI-2wint inhibits hepatitis C virus entry. PLoS One (2008) 1.86
The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis. Dev Cell (2011) 1.82
Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat Immunol (2011) 1.76
Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease. PLoS Genet (2006) 1.74
Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma. Gastroenterology (2012) 1.67
Detection of BRAF p.V600E mutations in melanomas: comparison of four methods argues for sequential use of immunohistochemistry and pyrosequencing. J Mol Diagn (2012) 1.66
Gene expression profiling identifies emerging oncogenic pathways operating in extranodal NK/T-cell lymphoma, nasal type. Blood (2009) 1.64
Natural killer cell IFN-gamma levels predict long-term survival with imatinib mesylate therapy in gastrointestinal stromal tumor-bearing patients. Cancer Res (2009) 1.64
Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors. Cancer Res (2013) 1.58
Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy. Intensive Care Med (2013) 1.56
A physical and functional link between cholesterol and tetraspanins. Eur J Immunol (2003) 1.54
Genes contributing to prion pathogenesis. J Gen Virol (2008) 1.51
MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice. J Pharmacol Exp Ther (2005) 1.51
EWI-2 is a new component of the tetraspanin web in hepatocytes and lymphoid cells. Biochem J (2003) 1.50
EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins. J Biol Chem (2006) 1.50
Differential stability of tetraspanin/tetraspanin interactions: role of palmitoylation. FEBS Lett (2002) 1.48
Competitive allele specific TaqMan PCR for KRAS, BRAF and EGFR mutation detection in clinical formalin fixed paraffin embedded samples. Exp Mol Pathol (2012) 1.48
BRAF mutation status in gastrointestinal stromal tumors. Am J Clin Pathol (2010) 1.47
Biogenesis of the demarcation membrane system (DMS) in megakaryocytes. Blood (2013) 1.47
Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis. Nat Med (2011) 1.46
Outcome of treatment in adults with Philadelphia chromosome-positive acute lymphoblastic leukemia--results of the prospective multicenter LALA-94 trial. Blood (2002) 1.44
Reduced fertility of female mice lacking CD81. Dev Biol (2005) 1.41
Novel 2-[(benzylamino)methyl]pyrrolidine-3,4-diol derivatives as alpha-mannosidase inhibitors and with antitumor activities against hematological and solid malignancies. Bioorg Med Chem (2010) 1.40
Erdheim-Chester disease. Curr Rheumatol Rep (2014) 1.35
Importance of T cells, gamma interferon, and tumor necrosis factor in immune control of the rapid grower Mycobacterium abscessus in C57BL/6 mice. Infect Immun (2007) 1.34
Multiple levels of interactions within the tetraspanin web. Biochem Biophys Res Commun (2003) 1.34
BCG-osis and tuberculosis in a child with chronic granulomatous disease. J Allergy Clin Immunol (2007) 1.34
The molecular players of sperm-egg fusion in mammals. Semin Cell Dev Biol (2006) 1.31
Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE. PLoS One (2009) 1.30
Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion. Blood (2007) 1.29
Single-molecule analysis of CD9 dynamics and partitioning reveals multiple modes of interaction in the tetraspanin web. J Cell Biol (2008) 1.29
Expression of human CD81 differently affects host cell susceptibility to malaria sporozoites depending on the Plasmodium species. Cell Microbiol (2006) 1.25
Analysis of the gamma-secretase interactome and validation of its association with tetraspanin-enriched microdomains. Nat Cell Biol (2009) 1.25
Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA. J Biol Chem (2003) 1.24
Cholesterol contributes to the organization of tetraspanin-enriched microdomains and to CD81-dependent infection by malaria sporozoites. J Cell Sci (2006) 1.23
HHV-8-associated Kaposi sarcoma in a child with IFNgammaR1 deficiency. J Pediatr (2004) 1.23
The tetraspanin CD81 regulates the expression of CD19 during B cell development in a postendoplasmic reticulum compartment. J Immunol (2003) 1.21
Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity. Arterioscler Thromb Vasc Biol (2005) 1.20
Immuno-fluorescence in situ hybridization index predicts survival in patients with diffuse large B-cell lymphoma treated with R-CHOP: a GELA study. J Clin Oncol (2009) 1.18
Prognostic value of BRAF(V⁶⁰⁰) mutations in melanoma patients after resection of metastatic lymph nodes. Ann Surg Oncol (2012) 1.18
CD9 controls the formation of clusters that contain tetraspanins and the integrin alpha 6 beta 1, which are involved in human and mouse gamete fusion. J Cell Sci (2006) 1.16
Membrane microdomains and proteomics: lessons from tetraspanin microdomains and comparison with lipid rafts. Proteomics (2006) 1.16
Outcome of patients with platelet-derived growth factor receptor alpha-mutated gastrointestinal stromal tumors in the tyrosine kinase inhibitor era. Clin Cancer Res (2012) 1.16
KIT mutations induce intracellular retention and activation of an immature form of the KIT protein in gastrointestinal stromal tumors. Clin Cancer Res (2008) 1.13
Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS. Proteomics (2006) 1.13
Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization. J Biol Chem (2006) 1.11
Tumor galectinology: insights into the complex network of a family of endogenous lectins. Glycoconj J (2004) 1.11
Residues SFQ (173-175) in the large extracellular loop of CD9 are required for gamete fusion. Development (2002) 1.09
Tetraspanin CD82 controls the association of cholesterol-dependent microdomains with the actin cytoskeleton in T lymphocytes: relevance to co-stimulation. J Cell Sci (2004) 1.08
New approach for high-throughput screening of drug activity on Plasmodium liver stages. Antimicrob Agents Chemother (2006) 1.08
EWI2/PGRL associates with the metastasis suppressor KAI1/CD82 and inhibits the migration of prostate cancer cells. Cancer Res (2003) 1.08
TspanC8 tetraspanins regulate ADAM10/Kuzbanian trafficking and promote Notch activation in flies and mammals. J Cell Biol (2012) 1.07
The tetraspanin protein, CD9, is expressed by progenitor cells committed to oligodendrogenesis and is linked to beta1 integrin, CD81, and Tspan-2. Glia (2002) 1.07
Erdheim-Chester disease. Rheum Dis Clin North Am (2013) 1.07
Alternative invasion pathways for Plasmodium berghei sporozoites. Int J Parasitol (2006) 1.06