Published in Proc Natl Acad Sci U S A on June 01, 1991
Functions of the gene products of Escherichia coli. Microbiol Rev (1993) 15.51
Spot 42 RNA mediates discoordinate expression of the E. coli galactose operon. Genes Dev (2002) 2.75
Protein-induced fit: the CRP activator protein changes sequence-specific DNA recognition by the CytR repressor, a highly flexible LacI member. EMBO J (1997) 1.45
Dual-function regulators: the cAMP receptor protein and the CytR regulator can act either to repress or to activate transcription depending on the context. Proc Natl Acad Sci U S A (1996) 1.31
Transcription activation at the Escherichia coli uhpT promoter by the catabolite gene activator protein. J Bacteriol (1995) 1.27
CRP induces the repositioning of MalT at the Escherichia coli malKp promoter primarily through DNA bending. EMBO J (1994) 1.13
DNA bending and expression of the divergent nagE-B operons. Nucleic Acids Res (1998) 0.99
The cyclic AMP (cAMP)-cAMP receptor protein complex functions both as an activator and as a corepressor at the tsx-p2 promoter of Escherichia coli K-12. J Bacteriol (1991) 0.98
A comparison of the DNA bending activities of the DNA binding proteins CRP and TFIID. Nucleic Acids Res (1992) 0.89
Repression of deoP2 in Escherichia coli by CytR: conversion of a transcription activator into a repressor. EMBO J (2001) 0.88
Amino acid substitutions in the CytR repressor which alter its capacity to regulate gene expression. J Bacteriol (1992) 0.87
Identification of the nucleotide sequence recognized by the cAMP-CRP dependent CytR repressor protein in the deoP2 promoter in E. coli. Nucleic Acids Res (1993) 0.79
Comparative genomics of CytR, an unusual member of the LacI family of transcription factors. PLoS One (2012) 0.77
Dynamic fluctuations provide the basis of a conformational switch mechanism in apo cyclic AMP receptor protein. PLoS Comput Biol (2013) 0.76
DNAse footprinting: a simple method for the detection of protein-DNA binding specificity. Nucleic Acids Res (1978) 30.43
A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system. Nucleic Acids Res (1981) 24.41
The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell (1990) 15.36
Cyclic AMP receptor protein: role in transcription activation. Science (1984) 8.37
Method for the isolation of the replication region of a bacterial replicon: construction of a mini-F'kn plasmid. J Bacteriol (1976) 5.75
Integration host factor: a protein for all reasons. Cell (1988) 5.68
Dual control for transcription of the galactose operon by cyclic AMP and its receptor protein at two interspersed promoters. Cell (1977) 5.29
The yeast cell-type-specific repressor alpha 2 acts cooperatively with a non-cell-type-specific protein. Cell (1988) 4.82
Molecular cloning and nucleotide sequencing of the gene for E. coli cAMP receptor protein. Nucleic Acids Res (1982) 4.77
The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Cell (1987) 4.49
MAT alpha 1 protein, a yeast transcription activator, binds synergistically with a second protein to a set of cell-type-specific genes. Cell (1987) 3.74
Host protein requirements for in vitro site-specific DNA inversion. Cell (1986) 3.31
Functional replacement of a protein-induced bend in a DNA recombination site. Nature (1989) 2.89
Purification and properties of the Escherichia coli host factor required for inversion of the G segment in bacteriophage Mu. J Biol Chem (1986) 2.75
Equilibrium studies of the cyclic AMP receptor protein-DNA interaction. J Mol Biol (1984) 2.49
Sites of allosteric shift in the structure of the cyclic AMP receptor protein. Cell (1985) 2.36
Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP. J Biol Chem (1982) 2.27
Scanning calorimetric study of the thermal unfolding of catabolite activator protein from Escherichia coli in the absence and presence of cyclic mononucleotides. Biochemistry (1988) 2.00
Long-range cooperativity between gene regulatory sequences in a prokaryote. Nature (1987) 1.84
Upstream repression and CRP stimulation of the Escherichia coli L-arabinose operon. J Mol Biol (1984) 1.84
Tandem CRP binding sites in the deo operon of Escherichia coli K-12. EMBO J (1982) 1.83
A complex nucleoprotein structure involved in activation of transcription of two divergent Escherichia coli promoters. J Mol Biol (1989) 1.82
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function. Proc Natl Acad Sci U S A (1987) 1.81
Mutations that alter the allosteric nature of cAMP receptor protein of Escherichia coli. EMBO J (1985) 1.80
Regulation of the deo operon in Escherichia coli: the double negative control of the deo operon by the cytR and deoR repressors in a DNA directed in vitro system. Mol Gen Genet (1978) 1.75
Tandem DNA-bound cAMP-CRP complexes are required for transcriptional repression of the deoP2 promoter by the CytR repressor in Escherichia coli. Mol Microbiol (1990) 1.10
The CytR repressor antagonizes cyclic AMP-cyclic AMP receptor protein activation of the deoCp2 promoter of Escherichia coli K-12. J Bacteriol (1990) 1.04
Transcriptional regulation of the cytR repressor gene of Escherichia coli: autoregulation and positive control by the cAMP/CAP complex. Mol Microbiol (1990) 1.03
CRP/cAMP- and CytR-regulated promoters in Escherichia coli K12: the cdd promoter. Mol Microbiol (1989) 1.02
Double negative and positive control of tsx expression in Escherichia coli. J Bacteriol (1988) 1.00
Fusion of the lac genes to the promotor for the cytidine deaminase gene of Escherichia coli K-12. Mol Gen Genet (1981) 0.90
Nucleotide sequence of the CytR regulatory gene of E. coli K-12. Nucleic Acids Res (1986) 2.14
Transcription of rpoH, encoding the Escherichia coli heat-shock regulator sigma32, is negatively controlled by the cAMP-CRP/CytR nucleoprotein complex. Mol Microbiol (1998) 1.90
Long-range cooperativity between gene regulatory sequences in a prokaryote. Nature (1987) 1.84
Tandem CRP binding sites in the deo operon of Escherichia coli K-12. EMBO J (1982) 1.83
The primary structure of the DeoR repressor from Escherichia coli K-12. Nucleic Acids Res (1985) 1.78
Nucleotide sequence of the Escherichia coli pyrE gene and of the DNA in front of the protein-coding region. Eur J Biochem (1983) 1.77
Regulation of the deo operon in Escherichia coli: the double negative control of the deo operon by the cytR and deoR repressors in a DNA directed in vitro system. Mol Gen Genet (1978) 1.75
Absence of axonemal arms in nasal mucosa cilia in Kartagener's syndrome. Nature (1976) 1.58
Body-wave imaging of Earth's mantle discontinuities from ambient seismic noise. Science (2012) 1.57
Acetylsalicylic acid in the prevention of stroke in patients with reversible cerebral ischemic attacks. A Danish cooperative study. Stroke (1983) 1.56
Protein-induced fit: the CRP activator protein changes sequence-specific DNA recognition by the CytR repressor, a highly flexible LacI member. EMBO J (1997) 1.45
The primary structure of Escherichia coli K12 2-deoxyribose 5-phosphate aldolase. Nucleotide sequence of the deoC gene and the amino acid sequence of the enzyme. Eur J Biochem (1982) 1.40
Evaluation of blood-warming devices with the apparent thermal clearance. Ann Emerg Med (1989) 1.39
DNA-binding characteristics of the Escherichia coli CytR regulator: a relaxed spacing requirement between operator half-sites is provided by a flexible, unstructured interdomain linker. Mol Microbiol (1998) 1.38
The maternal and fetal effects of milrinone and dopamine in normotensive pregnant ewes. Am J Obstet Gynecol (1992) 1.38
Dual-function regulators: the cAMP receptor protein and the CytR regulator can act either to repress or to activate transcription depending on the context. Proc Natl Acad Sci U S A (1996) 1.31
A flexible partnership: the CytR anti-activator and the cAMP-CRP activator protein, comrades in transcription control. Mol Microbiol (1996) 1.21
Diagnostic problems with meningococcal disease in general practice. J Clin Epidemiol (1992) 1.21
The influence of maternal psychological stress on the fetus. Am J Obstet Gynecol (1978) 1.19
The internal regulated promoter of the deo operon of Escherichia coli K-12. Nucleic Acids Res (1984) 1.17
Structure and function of the intercistronic regulatory deoC-deoA element of Escherichia coli K-12. EMBO J (1984) 1.16
Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity. J Med Chem (1994) 1.16
Recreational soccer is an effective health-promoting activity for untrained men. Br J Sports Med (2008) 1.16
A second purine nucleoside phosphorylase in Escherichia coli K-12. I. Xanthosine phosphorylase regulatory mutants isolated as secondary-site revertants of a deoD mutant. Mol Gen Genet (1980) 1.14
On the structure of the deo operon of Escherichia coli. Mol Gen Genet (1977) 1.11
Protein-protein interactions in gene regulation: the cAMP-CRP complex sets the specificity of a second DNA-binding protein, the CytR repressor. Cell (1993) 1.11
Tandem DNA-bound cAMP-CRP complexes are required for transcriptional repression of the deoP2 promoter by the CytR repressor in Escherichia coli. Mol Microbiol (1990) 1.10
Heterologous cooperativity in Escherichia coli. The CytR repressor both contacts DNA and the cAMP receptor protein when binding to the deoP2 promoter. J Biol Chem (1991) 1.10
Comparative three-dimensional analysis of CT-scans of the calvaria and cranial base in Apert and Crouzon syndromes. J Craniomaxillofac Surg (1993) 1.06
The CytR repressor antagonizes cyclic AMP-cyclic AMP receptor protein activation of the deoCp2 promoter of Escherichia coli K-12. J Bacteriol (1990) 1.04
Transcriptional regulation of the cytR repressor gene of Escherichia coli: autoregulation and positive control by the cAMP/CAP complex. Mol Microbiol (1990) 1.03
Absence of arms in the axoneme of immobile human spermatozoa. Biol Reprod (1975) 1.03
Evidence for the existence of three promoters for the deo operon of Escherichia coli K12 in vitro. J Mol Biol (1979) 1.02
Urokinase receptor in breast cancer tissue extracts. Enzyme-linked immunosorbent assay with a combination of mono- and polyclonal antibodies. Breast Cancer Res Treat (1995) 1.01
Protein-protein communication: structural model of the repression complex formed by CytR and the global regulator CRP. Cell (1997) 1.00
Analysis of the tsx gene, which encodes a nucleoside-specific channel-forming protein (Tsx) in the outer membrane of Escherichia coli. Gene (1990) 1.00
Further observations on the fine structure of the human spermatozoon. Z Zellforsch Mikrosk Anat (1972) 1.00
Fine structure of round-headed human spermatozoa. J Reprod Fertil (1974) 0.99
Low cerebral blood flow: a risk factor in the neonate. J Pediatr (1979) 0.99
Sperm chromatin heterogeneity as an infertility factor. Arch Androl (1988) 0.98
A novel function of the cAMP-CRP complex in Escherichia coli: cAMP-CRP functions as an adaptor for the CytR repressor in the deo operon. Mol Microbiol (1991) 0.98
The cyclic AMP (cAMP)-cAMP receptor protein complex functions both as an activator and as a corepressor at the tsx-p2 promoter of Escherichia coli K-12. J Bacteriol (1991) 0.98
A rat model of reproducible cerebral infarction using thrombotic blood clot emboli. J Cereb Blood Flow Metab (1992) 0.98
Organization and transcriptional regulation of the Escherichia coli K-12 D-serine tolerance locus. J Bacteriol (1995) 0.97
Uridine-cytidine kinase from Escherichia coli. Methods Enzymol (1978) 0.97
Phenylalanine depletion for the management of phenylketonuria: use of enzyme reactors with immobilized enzymes. Science (1978) 0.95
Ultrastructure of the ejaculated human sperm. Z Zellforsch Mikrosk Anat (1969) 0.95
Carbamazepine vs phenytoin. A controlled clinical trial in focal motor and generalized epilepsy. Arch Neurol (1979) 0.94
Tumours of the thymic region. Symptomatology, diagnosis, treatment, and prognosis. Thorax (1975) 0.94
Anesthetic risk in the pregnant surgical patient. Anesthesiology (1979) 0.93
Observations on the axial filament complex of the human spermatozoon. J Ultrastruct Res (1970) 0.93
Two-phase airlift fermentor operation with elicitation for the enhanced production of enzophenanthridine alkaloids in cell suspensions of Escherichia californica. Biotechnol Bioeng (1994) 0.92
[Study of the phenotypic occurrence of ura gene inactivation in Bacillus subtilis]. Genetika (2000) 0.92
Gene-regulatory modules in Escherichia coli: nucleoprotein complexes formed by cAMP-CRP and CytR at the nupG promoter. Mol Microbiol (1995) 0.91
Reduction of infarct volume and mortality by thrombolysis in a rat embolic stroke model. Stroke (1992) 0.90
Characterization of promoter recognition complexes formed by CRP and CytR for repression and by CRP and RNA polymerase for activation of transcription on the Escherichia coli deoP2 promoter. J Biol Chem (1993) 0.90
Analysis of the terminator region after the deoCABD operon of Escherichia coli K-12 using a new class of single copy number operon-fusion vectors. Nucleic Acids Res (1987) 0.89
Effect of hypothermia and delayed thrombolysis in a rat embolic stroke model. Acta Neurol Scand (1994) 0.89
Increasing secondary metabolite production in plant-cell culture by redirecting transport. Trends Biotechnol (1993) 0.89
Repression of deoP2 in Escherichia coli by CytR: conversion of a transcription activator into a repressor. EMBO J (2001) 0.88
Interval and strength training in CAD patients. Int J Sports Med (2010) 0.88
The influence of body temperature on infarct volume and thrombolytic therapy in a rat embolic stroke model. Brain Res (1994) 0.87
Systemic toxicity of ropivacaine during ovine pregnancy. Anesthesiology (1991) 0.87
Long-term prognosis and quality of life after reversible cerebral ischemic attacks. Acta Neurol Scand (1989) 0.86
Isolation and initial characterization of the uridine phosphorylase from Salmonella typhimurium. Biochemistry (Mosc) (1998) 0.86
CytR/cAMP-CRP nucleoprotein formation in E. coli: the CytR repressor binds its operator as a stable dimer in a ternary complex with cAMP-CRP. J Mol Biol (1996) 0.86
Early treatment of meningococcal disease. BMJ (1992) 0.86
The acrosome of the human spermatozoon: a new method for its extraction, and an analysis of its trypsin-like enzyme activity. J Reprod Fertil (1972) 0.86
Prognosis in infantile hydrocephalus. Follow-up in adult patients, born 1946-1955. Acta Neurol Scand (1982) 0.86
cAMP-CRP activator complex and the CytR repressor protein bind co-operatively to the cytRP promoter in Escherichia coli and CytR antagonizes the cAMP-CRP-induced DNA bend. J Mol Biol (1992) 0.85
Angiotensin-converting enzyme inhibition and regional cerebral blood flow in acute stroke. J Cardiovasc Pharmacol (1989) 0.85
Absence of human placental lactogen in an otherwise uneventful pregnancy. Am J Obstet Gynecol (1979) 0.85
Effect of delayed thrombolysis with rt-PA in a rat embolic stroke model. J Cereb Blood Flow Metab (1994) 0.85
Dissection of a surface-exposed portion of the cAMP-CRP complex that mediates transcription activation and repression. Mol Microbiol (1999) 0.85
Conservative treatment with total parenteral nutrition in patients with gastroesophageal anastomotic leaks (anastomotic leaks conservatively treated). Acta Chir Scand (1979) 0.85
Current controversies in obstetric anesthesia. Anesth Analg (1994) 0.85
Consulting for substance abuse: mental disorders among adolescents and their parents. Nord J Psychiatry (2007) 0.84
Extremely low placental lactogen hormone (hPL) values in an otherwise uneventful pregnancy preceding delivery of a normal baby. Acta Obstet Gynecol Scand (1978) 0.84
Thrombolytic therapy in acute ischemic stroke. A Danish pilot study. Stroke (1993) 0.84
Bupivacaine toxicity in pregnant and nonpregnant ewes. Anesthesiology (1985) 0.84
Bioactivity of prolactin in a woman with an excess of large molecular size prolactin, persistent hyperprolactinemia and spontaneous conception. Fertil Steril (1982) 0.84
Protein-ligand interaction: grafting of the uridine-specific determinants from the CytR regulator of Salmonella typhimurium to Escherichia coli CytR. J Mol Biol (1999) 0.84
The postacrosomal region of the spermatozoa of man and Macaca arctoides. J Ultrastruct Res (1972) 0.83
Spontaneous remission of cerebral palsy. Neuropediatrics (1986) 0.83
Brain biopsy in AIDS. Diagnostic value and consequence. Acta Neurochir (Wien) (1994) 0.83
The prognostic significance of weight loss and its integration in stage-grouping of oesophageal cancer. Acta Chir Scand (1982) 0.83
Absence of dynein arms in endometrial cilia: cause of infertility? Acta Obstet Gynecol Scand (1983) 0.83
Osteochondritis dissecans of the femoral condyle treated with periosteal transplantation. Poor outcome in 14 patients followed for 6-9 years. Acta Orthop Scand (1998) 0.82
Further observations on the Dag-defect of the tail of the bull spermatozoon. J Reprod Fertil (1971) 0.82
Production and elicitation of benzalacetone and the raspberry ketone in cell suspension cultures of Rubus idaeus. Biotechnol Prog (2000) 0.82