Published in Curr Alzheimer Res on February 01, 2006
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Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker. PLoS One (2011) 1.01
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All in the Family: How the APPs Regulate Neurogenesis. Front Neurosci (2012) 0.90
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The potential of hematopoietic growth factors for treatment of Alzheimer's disease: a mini-review. BMC Neurosci (2008) 0.78
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Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease. J Cell Biol (2005) 4.91
Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J Neurosci (2003) 2.35
Lysosomal system pathways: genes to neurodegeneration in Alzheimer's disease. J Alzheimers Dis (2006) 1.83
Alzheimer's-related endosome dysfunction in Down syndrome is Abeta-independent but requires APP and is reversed by BACE-1 inhibition. Proc Natl Acad Sci U S A (2009) 1.72
Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production. J Biol Chem (2003) 1.60
Microarray analysis of hippocampal CA1 neurons implicates early endosomal dysfunction during Alzheimer's disease progression. Biol Psychiatry (2010) 1.49
Interleukin-1 mediates Alzheimer and Lewy body pathologies. J Neuroinflammation (2006) 1.47
Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide. J Neuroinflammation (2004) 1.25
Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease. Am J Pathol (2008) 1.22
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet (2009) 1.18
Mechanisms of ZnII-activated magnetic resonance imaging agents. Inorg Chem (2008) 1.14
S100B-induced microglial and neuronal IL-1 expression is mediated by cell type-specific transcription factors. J Neurochem (2005) 1.13
Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression. J Neurosci (2008) 1.13
Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: lessons from lithium. Curr Alzheimer Res (2007) 1.08
Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK. Neurobiol Aging (2005) 1.06
Cytokines and the aging brain - what we don't know might help us. Trends Neurosci (2004) 1.04
Induction of serine racemase by inflammatory stimuli is dependent on AP-1. Ann N Y Acad Sci (2004) 1.02
NFkappaB in neurons? The uncertainty principle in neurobiology. J Neurochem (2006) 1.01
Age-dependent dysregulation of brain amyloid precursor protein in the Ts65Dn Down syndrome mouse model. J Neurochem (2009) 1.01
Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis. J Biol Chem (2001) 1.00
Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice. Learn Mem (2008) 0.98
Unique aspects of transcriptional regulation in neurons--nuances in NFkappaB and Sp1-related factors. J Neuroinflammation (2009) 0.98
Differential transcriptional control of the superoxide dismutase-2 kappaB element in neurons and astrocytes. J Biol Chem (2006) 0.96
Glutamate receptor activation evokes calpain-mediated degradation of Sp3 and Sp4, the prominent Sp-family transcription factors in neurons. J Neurochem (2007) 0.96
Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis. J Neurosci (2007) 0.95
Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors. J Neuroinflammation (2011) 0.92
Regulation of Collagen Gene Expression by Prostaglandins and Interleukin-1beta in Cultured Chondrocytes and Fibroblasts. Am J Ther (1996) 0.92
In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model. Neurobiol Aging (2008) 0.89
Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP). Curr Alzheimer Res (2007) 0.88
Neuronal kappa B-binding factors consist of Sp1-related proteins. Functional implications for autoregulation of N-methyl-D-aspartate receptor-1 expression. J Biol Chem (2002) 0.88
Paradoxical roles of serine racemase and D-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis. J Neurochem (2012) 0.86
Neuroinflammatory Cytokines-The Common Thread in Alzheimer's Pathogenesis. US Neurol (2010) 0.86
Roles of quaternary structure and cysteine residues in the activity of human serine racemase. BMC Biochem (2011) 0.83
Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy. J Neuroinflammation (2011) 0.83
Bioluminescence imaging as a tool to evaluate germ cells in vitro and transplantation in vivo as fertility preservation of prepubertal male mice. Fertil Steril (2012) 0.83
Metabotropic glutamate receptors inhibit microglial glutamate release. ASN Neuro (2012) 0.82
Different forms of tenascin-C with tenascin-R regulate neural differentiation in bone marrow-derived human mesenchymal stem cells. Tissue Eng Part A (2014) 0.82
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists. J Neurosci Res (2005) 0.82
The PPAR-gamma Agonist 15-Deoxy-Delta-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease. PPAR Res (2008) 0.81
Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes. J Biol Chem (2002) 0.81
Schwann cell and epineural fibroblast expression of serine racemase. Brain Res (2004) 0.81
Microglial activation by uptake of fDNA via a scavenger receptor. J Neuroimmunol (2004) 0.80
A polymorphism in the upstream regulatory region of the interleukin-1α gene confers differential binding by transcription factors of the AP-1 family. Life Sci (2012) 0.80
Tracking the rejection and survival of mouse ovarian iso- and allografts in vivo with bioluminescent imaging. Reproduction (2010) 0.80
Detection of intranasally delivered bone marrow-derived mesenchymal stromal cells in the lesioned mouse brain: a cautionary report. Stem Cells Int (2011) 0.80
Reductions of the components of the calreticulin/calnexin quality-control system by proteasome inhibitors and their relevance in a rodent model of Parkinson's disease. J Neurosci Res (2014) 0.79
Nox4-generated superoxide drives angiotensin II-induced neural stem cell proliferation. Dev Neurosci (2013) 0.78
Screening of flavonoids for effective osteoclastogenesis suppression. Anal Biochem (2012) 0.76
Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species. J Neurosci Res (2012) 0.76
Apolipoprotein E acts at pre-synaptic sites...among others. J Neurochem (2012) 0.75
TMEM106B and frontotemporal lobar degeneration: can over-expression tell us how reductions are beneficial? J Neurochem (2013) 0.75
Characterization of purified rat testicular transglutaminase and age-dependent changes of the enzyme activities. Int J Biochem Cell Biol (2005) 0.75