Published in BMC Biochem on December 08, 2011
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Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species. J Neurosci Res (2012) 0.76
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Purification of serine racemase: biosynthesis of the neuromodulator D-serine. Proc Natl Acad Sci U S A (1999) 2.27
D-serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J Neurosci (1997) 1.93
Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration. Proc Natl Acad Sci U S A (2005) 1.68
D-serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors. Proc Natl Acad Sci U S A (2003) 1.57
The presence of free D-serine in rat brain. FEBS Lett (1992) 1.47
NMDA- and beta-amyloid1-42-induced neurotoxicity is attenuated in serine racemase knock-out mice. J Neurosci (2008) 1.27
Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proc Natl Acad Sci U S A (2007) 1.27
D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis. EMBO J (2007) 1.26
The disulfide proteome and other reactive cysteine proteomes: analysis and functional significance. Antioxid Redox Signal (2011) 1.25
Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide. J Neuroinflammation (2004) 1.25
Direct calcium binding results in activation of brain serine racemase. J Biol Chem (2002) 1.22
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet (2009) 1.18
The involvement of the NMDA receptor D-serine/glycine site in the pathophysiology and treatment of schizophrenia. Neurosci Biobehav Rev (2009) 1.18
The redox switch: dynamic regulation of protein function by cysteine modifications. Physiol Plant (2009) 1.17
Bicarbonate-dependent peroxidase activity of human Cu,Zn-superoxide dismutase induces covalent aggregation of protein: intermediacy of tryptophan-derived oxidation products. J Biol Chem (2003) 1.13
Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: therapeutic implications. J Neurochem (2009) 1.13
Human serine racemase: moleular cloning, genomic organization and functional analysis. Gene (2000) 1.11
Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition. Proc Natl Acad Sci U S A (2009) 1.09
Serine racemase binds to PICK1: potential relevance to schizophrenia. Mol Psychiatry (2006) 1.08
Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity. Biochemistry (2005) 1.07
Formation, reactivity, and detection of protein sulfenic acids. Chem Res Toxicol (2010) 1.05
Induction of serine racemase by inflammatory stimuli is dependent on AP-1. Ann N Y Acad Sci (2004) 1.02
Modulation of D-serine levels in brains of mice lacking PICK1. Biol Psychiatry (2008) 0.98
Allosteric regulation of mouse brain serine racemase. Neurochem Res (2002) 0.91
Reduced serine racemase expression contributes to age-related deficits in hippocampal cognitive function. Neurobiol Aging (2009) 0.90
Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP). Curr Alzheimer Res (2007) 0.88
The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding. J Biol Chem (2010) 0.88
Mutual regulation between serine and nitric oxide metabolism in human glioblastoma cells. Neurosci Lett (2005) 0.88
Regulation of serine racemase activity by D-serine and nitric oxide in human glioblastoma cells. Neurosci Lett (2005) 0.85
Regulation of serine racemase activity by amino acids. Brain Res Mol Brain Res (2005) 0.84
Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP. FEBS J (2007) 0.79
Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway. J Neurosci (2003) 2.35
Interleukin-1 mediates Alzheimer and Lewy body pathologies. J Neuroinflammation (2006) 1.47
Induction of serine racemase expression and D-serine release from microglia by amyloid beta-peptide. J Neuroinflammation (2004) 1.25
Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum Mol Genet (2009) 1.18
S100B-induced microglial and neuronal IL-1 expression is mediated by cell type-specific transcription factors. J Neurochem (2005) 1.13
Glycogen synthase kinase-3 in neurodegeneration and neuroprotection: lessons from lithium. Curr Alzheimer Res (2007) 1.08
Secreted beta-amyloid precursor protein activates microglia via JNK and p38-MAPK. Neurobiol Aging (2005) 1.06
Cytokines and the aging brain - what we don't know might help us. Trends Neurosci (2004) 1.04
Induction of serine racemase by inflammatory stimuli is dependent on AP-1. Ann N Y Acad Sci (2004) 1.02
NFkappaB in neurons? The uncertainty principle in neurobiology. J Neurochem (2006) 1.01
Genetic inactivation of D-amino acid oxidase enhances extinction and reversal learning in mice. Learn Mem (2008) 0.98
Unique aspects of transcriptional regulation in neurons--nuances in NFkappaB and Sp1-related factors. J Neuroinflammation (2009) 0.98
Differential transcriptional control of the superoxide dismutase-2 kappaB element in neurons and astrocytes. J Biol Chem (2006) 0.96
Glutamate receptor activation evokes calpain-mediated degradation of Sp3 and Sp4, the prominent Sp-family transcription factors in neurons. J Neurochem (2007) 0.96
Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors. J Neuroinflammation (2011) 0.92
Induction of serine racemase expression and D-serine release from microglia by secreted amyloid precursor protein (sAPP). Curr Alzheimer Res (2007) 0.88
Neuronal kappa B-binding factors consist of Sp1-related proteins. Functional implications for autoregulation of N-methyl-D-aspartate receptor-1 expression. J Biol Chem (2002) 0.88
sAPPalpha enhances the transdifferentiation of adult bone marrow progenitor cells to neuronal phenotypes. Curr Alzheimer Res (2006) 0.87
Neuroinflammatory Cytokines-The Common Thread in Alzheimer's Pathogenesis. US Neurol (2010) 0.86
Paradoxical roles of serine racemase and D-serine in the G93A mSOD1 mouse model of amyotrophic lateral sclerosis. J Neurochem (2012) 0.86
Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy. J Neuroinflammation (2011) 0.83
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists. J Neurosci Res (2005) 0.82
Metabotropic glutamate receptors inhibit microglial glutamate release. ASN Neuro (2012) 0.82
The PPAR-gamma Agonist 15-Deoxy-Delta-Prostaglandin J(2) Attenuates Microglial Production of IL-12 Family Cytokines: Potential Relevance to Alzheimer's Disease. PPAR Res (2008) 0.81
Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes. J Biol Chem (2002) 0.81
Schwann cell and epineural fibroblast expression of serine racemase. Brain Res (2004) 0.81
Microglial activation by uptake of fDNA via a scavenger receptor. J Neuroimmunol (2004) 0.80
A polymorphism in the upstream regulatory region of the interleukin-1α gene confers differential binding by transcription factors of the AP-1 family. Life Sci (2012) 0.80
Reductions of the components of the calreticulin/calnexin quality-control system by proteasome inhibitors and their relevance in a rodent model of Parkinson's disease. J Neurosci Res (2014) 0.79
Nox4-generated superoxide drives angiotensin II-induced neural stem cell proliferation. Dev Neurosci (2013) 0.78
Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species. J Neurosci Res (2012) 0.76
TMEM106B and frontotemporal lobar degeneration: can over-expression tell us how reductions are beneficial? J Neurochem (2013) 0.75
Apolipoprotein E acts at pre-synaptic sites...among others. J Neurochem (2012) 0.75