Published in FEBS Lett on February 09, 2006
Structural Design of Engineered Costimulation Determines Tumor Rejection Kinetics and Persistence of CAR T Cells. Cancer Cell (2015) 1.74
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol (2008) 1.42
4-1BB ligand signaling to T cells limits T cell activation. J Immunol (2014) 0.82
Cross-linking of CD137 ligand modulates immune responses of thioglycollate-elicited mouse peritoneal macrophages. Inflamm Res (2010) 0.78
4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat Med (2004) 3.01
4-1BB promotes the survival of CD8+ T lymphocytes by increasing expression of Bcl-xL and Bfl-1. J Immunol (2002) 2.05
Clinicopathologic characteristics and prognostic factors in 10 783 patients with gastric cancer. Gastric Cancer (1998) 1.79
PIE: an online prediction system for protein-protein interactions from text. Nucleic Acids Res (2008) 1.76
Discovery of microRNA-mRNA modules via population-based probabilistic learning. Bioinformatics (2007) 1.70
Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages. Nat Immunol (2007) 1.57
Generation and analysis of end sequence database for T-DNA tagging lines in rice. Plant Physiol (2003) 1.56
4-1BB-dependent inhibition of immunosuppression by activated CD4+CD25+ T cells. J Leukoc Biol (2003) 1.54
Permanent epicardial pacing in pediatric patients: 12-year experience at a single center. Ann Thorac Surg (2011) 1.52
Predictive value of intraoperative transesophageal echocardiography in complete atrioventricular septal defect. Ann Thorac Surg (2005) 1.49
Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells. Nat Immunol (2008) 1.42
Surgical strategy for pulmonary coarctation in the univentricular heart. Eur J Cardiothorac Surg (2005) 1.42
Involvement of TL1A and DR3 in induction of pro-inflammatory cytokines and matrix metalloproteinase-9 in atherogenesis. Cytokine (2005) 1.40
Peptide-specific CD8 T regulatory cells use IFN-gamma to elaborate TGF-beta-based suppression. J Immunol (2005) 1.38
TWEAK can induce pro-inflammatory cytokines and matrix metalloproteinase-9 in macrophages. Circ J (2004) 1.33
CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice. Circulation (2010) 1.26
CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses. J Immunol (2004) 1.22
Functional dichotomy between OX40 and 4-1BB in modulating effector CD8 T cell responses. J Immunol (2006) 1.21
Immunotherapy of cancer with 4-1BB. Mol Cancer Ther (2012) 1.19
Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent. J Clin Invest (2007) 1.17
Cardiovascular anomalies in patients with chromosome 22q11.2 deletion: a Korean multicenter study. Int J Cardiol (2006) 1.16
Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor. Blood (2005) 1.14
Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells. Blood (2004) 1.13
4-1BB-mediated amelioration of experimental autoimmune uveoretinitis is caused by indoleamine 2,3-dioxygenase-dependent mechanisms. Cytokine (2006) 1.13
Early replacement of pulmonary valve after repair of tetralogy: is it really beneficial? Eur J Cardiothorac Surg (2004) 1.10
Dual immunoregulatory pathways of 4-1BB signaling. J Mol Med (Berl) (2006) 1.09
4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation. J Immunol (2008) 1.08
Mechanisms involved in synergistic anticancer immunity of anti-4-1BB and anti-CD4 therapy. Cancer Res (2007) 1.08
4-1BB enhances CD8+ T cell expansion by regulating cell cycle progression through changes in expression of cyclins D and E and cyclin-dependent kinase inhibitor p27kip1. Eur J Immunol (2003) 1.06
4-1BB functions as a survival factor in dendritic cells. J Immunol (2009) 1.05
Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis. J Immunol (2003) 1.05
LIGHT enhances the bactericidal activity of human monocytes and neutrophils via HVEM. J Leukoc Biol (2005) 1.04
Enhanced CD4 T cell responsiveness in the absence of 4-1BB. J Immunol (2005) 1.04
Analyses of bacterial communities in meju, a Korean traditional fermented soybean bricks, by cultivation-based and pyrosequencing methods. J Microbiol (2011) 1.04
Human CC chemokine CCL23, a ligand for CCR1, induces endothelial cell migration and promotes angiogenesis. Cytokine (2005) 1.04
Aortic dissection late after repair of tetralogy of Fallot. Int J Cardiol (2005) 1.03
Evaluating the cellular targets of anti-4-1BB agonist antibody during immunotherapy of a pre-established tumor in mice. PLoS One (2010) 1.02
4-1BB (CD137) is required for rapid clearance of Listeria monocytogenes infection. Infect Immun (2005) 1.02
Osteoclastogenesis by bone marrow-derived macrophages is enhanced in obese mice. J Nutr (2009) 1.00
Saturated fatty acids enhance osteoclast survival. J Lipid Res (2010) 1.00
Combined CD137 (4-1BB) and adjuvant therapy generates a developing pool of peptide-specific CD8 memory T cells. Int Immunol (2005) 0.99
Reverse signaling through BAFF differentially regulates the expression of inflammatory mediators and cytoskeletal movements in THP-1 cells. Immunol Cell Biol (2009) 0.99
Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation. Proc Natl Acad Sci U S A (2011) 0.99
Recombinant glucocorticoid induced tumor necrosis factor receptor (rGITR) induces NOS in murine macrophage. FEBS Lett (2002) 0.99
4-1BB signaling beyond T cells. Cell Mol Immunol (2011) 0.99
Durability of bioprosthetic valves in the pulmonary position: long-term follow-up of 181 implants in patients with congenital heart disease. J Thorac Cardiovasc Surg (2011) 0.99
Angiogenic activity of human CC chemokine CCL15 in vitro and in vivo. FEBS Lett (2004) 0.98
Cross-linking of 4-1BB activates TCR-signaling pathways in CD8+ T lymphocytes. J Immunol (2005) 0.97
Reverse signaling initiated from GITRL induces NF-kappaB activation through ERK in the inflammatory activation of macrophages. Mol Immunol (2007) 0.97
CD134 Costimulation Couples the CD137 Pathway to Induce Production of Supereffector CD8 T Cells That Become IL-7 Dependent. J Immunol (2007) 0.97
Ginsenoside Rh2 induces Bcl-2 family proteins-mediated apoptosis in vitro and in xenografts in vivo models. J Cell Biochem (2011) 0.97
Description of Microvirga aerophila sp. nov. and Microvirga aerilata sp. nov., isolated from air, reclassification of Balneimonas flocculans Takeda et al. 2004 as Microvirga flocculans comb. nov. and emended description of the genus Microvirga. Int J Syst Evol Microbiol (2009) 0.97
Glucocorticoid-induced tumour necrosis factor receptor family related protein (GITR) mediates inflammatory activation of macrophages that can destabilize atherosclerotic plaques. Immunology (2006) 0.95
Partial anomalous pulmonary venous connection to the superior vena cava: the outcome after the Warden procedure. Eur J Cardiothorac Surg (2011) 0.95
4-1BB costimulation enhances HSV-1-specific CD8+ T cell responses by the induction of CD11c+CD8+ T cells. Cell Immunol (2006) 0.95
Adult stem cells from the hyaluronic acid-rich node and duct system differentiate into neuronal cells and repair brain injury. Stem Cells Dev (2014) 0.93
Characterization of monoclonal antibody specific to the Z39Ig protein, a member of immunoglobulin superfamily. Immunol Lett (2005) 0.93
CD137 is required for M cell functional maturation but not lineage commitment. Am J Pathol (2010) 0.92
MCP-1 derived from stromal keratocyte induces corneal infiltration of CD4+ T cells in herpetic stromal keratitis. Mol Cells (2008) 0.92
Ectopic expression of OsYAB1 causes extra stamens and carpels in rice. Plant Mol Biol (2004) 0.91
Characterization of an abiotic stress-inducible dehydrin gene, OsDhn1, in rice (Oryza sativa L.). Mol Cells (2005) 0.91
The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily. J Biol Chem (2009) 0.91
Potent costimulation of human CD8 T cells by anti-4-1BB and anti-CD28 on synthetic artificial antigen presenting cells. Cancer Immunol Immunother (2007) 0.91
Soluble glucocorticoid-induced tumor necrosis factor receptor (sGITR) increased MMP-9 activity in murine macrophage. J Cell Biochem (2003) 0.90
Combination therapy with cisplatin and anti-4-1BB: synergistic anticancer effects and amelioration of cisplatin-induced nephrotoxicity. Cancer Res (2008) 0.90
Human CC chemokine CCL23 enhances expression of matrix metalloproteinase-2 and invasion of vascular endothelial cells. Biochem Biophys Res Commun (2005) 0.90
Massilia jejuensis sp. nov. and Naxibacter suwonensis sp. nov., isolated from air samples. Int J Syst Evol Microbiol (2009) 0.90
Absence of MCP-1 leads to elevated bone mass via impaired actin ring formation. J Cell Physiol (2012) 0.90
Stimulation of osteoclastogenesis by enhanced levels of MIP-1alpha in BALB/c mice in vitro. Exp Hematol (2007) 0.90
Enhanced osteoclastogenesis in 4-1BB-deficient mice caused by reduced interleukin-10. J Bone Miner Res (2006) 0.89
The OsFOR1 gene encodes a polygalacturonase-inhibiting protein (PGIP) that regulates floral organ number in rice. Plant Mol Biol (2003) 0.89
Novel metagenome-derived carboxylesterase that hydrolyzes β-lactam antibiotics. Appl Environ Microbiol (2011) 0.89
4-1BB triggering ameliorates experimental autoimmune encephalomyelitis by modulating the balance between Th17 and regulatory T cells. J Immunol (2011) 0.89
Impaired antioxidant status and decreased dietary intake of antioxidants in patients with systemic lupus erythematosus. Rheumatol Int (2002) 0.88
Z39Ig is expressed on macrophages and may mediate inflammatory reactions in arthritis and atherosclerosis. J Leukoc Biol (2006) 0.88
4-1BB triggers IL-13 production from T cells to limit the polarized, Th1-mediated inflammation. J Leukoc Biol (2007) 0.88
Transcatheter closure of secundum atrial septal defect in patients over 60 years old. Korean Circ J (2013) 0.87
Protective effects of an extract of young radish (Raphanus sativus L) cultivated with sulfur (sulfur-radish extract) and of sulforaphane on carbon tetrachloride-induced hepatotoxicity. Biosci Biotechnol Biochem (2008) 0.87
The recent surgical result of total anomalous pulmonary venous return. Korean Circ J (2010) 0.87
Inadequate antioxidant nutrient intake and altered plasma antioxidant status of rheumatoid arthritis patients. J Am Coll Nutr (2003) 0.87
Immunity to melanoma mediated by 4-1BB is associated with enhanced activity of tumour-infiltrating lymphocytes. Immunol Cell Biol (2005) 0.87
Increased fat due to estrogen deficiency induces bone loss by elevating monocyte chemoattractant protein-1 (MCP-1) production. Mol Cells (2010) 0.87
Pleomorphomonas diazotrophica sp. nov., an endophytic N-fixing bacterium isolated from root tissue of Jatropha curcas L. Int J Syst Evol Microbiol (2012) 0.86
Amelioration of mercury-induced autoimmunity by 4-1BB. J Immunol (2006) 0.86
New insights into the role of 4-1BB in immune responses: beyond CD8+ T cells. Trends Immunol (2002) 0.86
PLP2/A4 interacts with CCR1 and stimulates migration of CCR1-expressing HOS cells. Biochem Biophys Res Commun (2004) 0.86
Leucobacter denitrificans sp. nov., isolated from cow dung. J Microbiol (2012) 0.86
Mechanisms involved in synergistic anticancer effects of anti-4-1BB and cyclophosphamide therapy. Mol Cancer Ther (2009) 0.86
Targeting TNF superfamily members for therapeutic intervention in rheumatoid arthritis. Cytokine (2011) 0.85
A foodborne outbreak of Staphylococcus aureus associated with fried chicken in Republic of Korea. J Microbiol Biotechnol (2013) 0.85
CD137 expressed on neutrophils plays dual roles in antibacterial responses against Gram-positive and Gram-negative bacterial infections. Infect Immun (2013) 0.85
Recombinant glucocorticoid induced tumour necrosis factor receptor (rGITR) induced COX-2 activity in murine macrophage Raw 264.7 cells. Cytokine (2002) 0.85
Truncus arteriosus with coarctation of persistent fifth aortic arch. Ann Thorac Surg (2002) 0.85
Marked expansion of CD11c+CD8+ T-cells in melanoma-bearing mice induced by anti-4-1BB monoclonal antibody. Mol Cells (2007) 0.85
Dyella thiooxydans sp. nov., a facultatively chemolithotrophic, thiosulfate-oxidizing bacterium isolated from rhizosphere soil of sunflower (Helianthus annuus L.). Int J Syst Evol Microbiol (2010) 0.85
Regulation of mouse 4-1BB expression: multiple promoter usages and a splice variant. Mol Cells (2011) 0.85
Immunotherapy targeting 4-1BB and its ligand. Int J Hematol (2006) 0.85