Published in J Am Chem Soc on March 01, 2006
Foldamers as versatile frameworks for the design and evolution of function. Nat Chem Biol (2007) 2.79
Infectious Disease: Connecting Innate Immunity to Biocidal Polymers. Mater Sci Eng R Rep (2007) 1.30
Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. Antimicrob Agents Chemother (2007) 1.24
Host defense peptides in the oral cavity and the lung: similarities and differences. J Dent Res (2008) 1.19
Biomolecular imaging with coherent nonlinear vibrational microscopy. Annu Rev Phys Chem (2012) 1.12
Molecular interactions between magainin 2 and model membranes in situ. J Phys Chem B (2009) 1.00
In situ molecular level studies on membrane related peptides and proteins in real time using sum frequency generation vibrational spectroscopy. J Struct Biol (2009) 0.97
Real-time structural investigation of a lipid bilayer during its interaction with melittin using sum frequency generation vibrational spectroscopy. Biophys J (2007) 0.94
Designing mimics of membrane active proteins. Acc Chem Res (2013) 0.93
Orientation, dynamics, and lipid interaction of an antimicrobial arylamide investigated by 19F and 31P solid-state NMR spectroscopy. J Am Chem Soc (2010) 0.93
Comparison of facially amphiphilic versus segregated monomers in the design of antibacterial copolymers. Chemistry (2009) 0.93
Interkingdom signaling: integration, conformation, and orientation of N-acyl-L-homoserine lactones in supported lipid bilayers. Langmuir (2012) 0.87
Molecular interaction of a new antibacterial polymer with a supported lipid bilayer measured by an in situ label-free optical technique. Int J Mol Sci (2013) 0.84
SFG analysis of surface bound proteins: a route towards structure determination. Phys Chem Chem Phys (2013) 0.83
Elucidation of molecular structures at buried polymer interfaces and biological interfaces using sum frequency generation vibrational spectroscopy. Soft Matter (2013) 0.80
Protein-phospholipid interactions in nonclassical protein secretion: problem and methods of study. Int J Mol Sci (2013) 0.79
Length-Dependent Formation of Transmembrane Pores by 310-Helical α-Aminoisobutyric Acid Foldamers. J Am Chem Soc (2016) 0.77
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol (2011) 18.34
RNA interference targeting Fas protects mice from fulminant hepatitis. Nat Med (2003) 7.37
Unsupervised pattern discovery in human chromatin structure through genomic segmentation. Nat Methods (2012) 4.89
Intercalated combination of chemotherapy and erlotinib for patients with advanced stage non-small-cell lung cancer (FASTACT-2): a randomised, double-blind trial. Lancet Oncol (2013) 4.20
Epidermal growth factor receptor mutations in plasma DNA samples predict tumor response in Chinese patients with stages IIIB to IV non-small-cell lung cancer. J Clin Oncol (2009) 3.58
Vandetanib plus docetaxel versus docetaxel as second-line treatment for patients with advanced non-small-cell lung cancer (ZODIAC): a double-blind, randomised, phase 3 trial. Lancet Oncol (2010) 3.30
Gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): a multicentre, double-blind randomised phase 3 trial. Lancet Oncol (2012) 2.98
Icotinib versus gefitinib in previously treated advanced non-small-cell lung cancer (ICOGEN): a randomised, double-blind phase 3 non-inferiority trial. Lancet Oncol (2013) 2.94
Chinese herbal formulas for treating hypertension in traditional Chinese medicine: perspective of modern science. Hypertens Res (2013) 2.55
Valganciclovir for suppression of human herpesvirus-8 replication: a randomized, double-blind, placebo-controlled, crossover trial. J Infect Dis (2008) 2.31
Influence of chemotherapy on EGFR mutation status among patients with non-small-cell lung cancer. J Clin Oncol (2012) 2.31
An ancient transcription factor initiates the burst of piRNA production during early meiosis in mouse testes. Mol Cell (2013) 2.23
Genomic binding profiles of functionally distinct RNA polymerase III transcription complexes in human cells. Nat Struct Mol Biol (2010) 2.15
Functional analysis of transcription factor binding sites in human promoters. Genome Biol (2012) 2.12
Reproducible copy number variation patterns among single circulating tumor cells of lung cancer patients. Proc Natl Acad Sci U S A (2013) 2.09
Developmental regulation and individual differences of neuronal H3K4me3 epigenomes in the prefrontal cortex. Proc Natl Acad Sci U S A (2010) 2.06
Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse. Diabetes (2003) 2.05
Cross-platform comparison of SYBR Green real-time PCR with TaqMan PCR, microarrays and other gene expression measurement technologies evaluated in the MicroArray Quality Control (MAQC) study. BMC Genomics (2008) 1.99
Central nervous system imprinting of the G protein G(s)alpha and its role in metabolic regulation. Cell Metab (2009) 1.98
Prevalence of the metabolic syndrome and its relation to cardiovascular disease in an elderly Chinese population. J Am Coll Cardiol (2006) 1.98
A novel nuclear factor-kappaB gene signature is differentially expressed in head and neck squamous cell carcinomas in association with TP53 status. Clin Cancer Res (2007) 1.96
Escherichia coli: development of carbapenem resistance during therapy. Clin Infect Dis (2005) 1.89
Development of heart failure in chronic hypertensive Dahl rats: focus on heart failure with preserved ejection fraction. Hypertension (2006) 1.87
PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 are associated with type 2 diabetes in a Chinese population. PLoS One (2009) 1.86
Toll-like receptor 3 mediates establishment of an antiviral state against hepatitis C virus in hepatoma cells. J Virol (2009) 1.85
Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons. Arch Gen Psychiatry (2011) 1.81
Heterotypic piRNA Ping-Pong requires qin, a protein with both E3 ligase and Tudor domains. Mol Cell (2011) 1.79
PKA phosphorylation activates the calcium release channel (ryanodine receptor) in skeletal muscle: defective regulation in heart failure. J Cell Biol (2003) 1.78
MIBPB: a software package for electrostatic analysis. J Comput Chem (2010) 1.77
Organization of the Caenorhabditis elegans small non-coding transcriptome: genomic features, biogenesis, and expression. Genome Res (2005) 1.77
Adaptation to P element transposon invasion in Drosophila melanogaster. Cell (2011) 1.76
Geometric and potential driving formation and evolution of biomolecular surfaces. J Math Biol (2008) 1.76
Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. J Biol Chem (2002) 1.73
A physiologic role for testosterone in limiting estrogenic stimulation of the breast. Menopause (2003) 1.71
High expression of trimethylated histone H3 lysine 4 is associated with poor prognosis in hepatocellular carcinoma. Hum Pathol (2012) 1.70
Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: the mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1. Cancer Biol Ther (2007) 1.70
NONCODE v2.0: decoding the non-coding. Nucleic Acids Res (2007) 1.69
Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases. J Virol (2010) 1.64
The impact of angiotensin-converting enzyme inhibitor therapy on the extracellular collagen matrix during left ventricular assist device support in patients with end-stage heart failure. J Am Coll Cardiol (2007) 1.63
Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis. J Clin Invest (2012) 1.63
MR diffusion tensor imaging study of postinfarct myocardium structural remodeling in a porcine model. Magn Reson Med (2007) 1.57
Antimicrobial polymers prepared by ROMP with unprecedented selectivity: a molecular construction kit approach. J Am Chem Soc (2008) 1.54
Surgical treatment strategies in chronic pancreatitis: a meta-analysis. Arch Surg (2012) 1.54
ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol (2011) 1.54
Mechanisms of heart failure with well preserved ejection fraction in dogs following limited coronary microembolization. Cardiovasc Res (2004) 1.53
UAP56 couples piRNA clusters to the perinuclear transposon silencing machinery. Cell (2012) 1.53
The effects of the TRPV1 antagonist SB-705498 on TRPV1 receptor-mediated activity and inflammatory hyperalgesia in humans. Pain (2007) 1.53
Single-beat estimation of end-diastolic pressure-volume relationship: a novel method with potential for noninvasive application. Am J Physiol Heart Circ Physiol (2006) 1.50
Mapping the C. elegans noncoding transcriptome with a whole-genome tiling microarray. Genome Res (2007) 1.46
Short- and long-term outcomes after laparoscopic and open hepatectomy for hepatocellular carcinoma: a global systematic review and meta-analysis. Ann Surg Oncol (2012) 1.46
Transvenous phrenic nerve stimulation in patients with Cheyne-Stokes respiration and congestive heart failure: a safety and proof-of-concept study. Chest (2012) 1.43
Tuning the hemolytic and antibacterial activities of amphiphilic polynorbornene derivatives. J Am Chem Soc (2004) 1.42
Dofetilide enhances the contractility of rat ventricular myocytes via augmentation of Na+-Ca 2+ exchange. Cardiovasc Drugs Ther (2009) 1.41
¹⁸F-FDG-PET and ¹⁸F-FDG-PET/CT in the detection of recurrent or metastatic medullary thyroid carcinoma: a systematic review and meta-analysis. J Med Imaging Radiat Oncol (2012) 1.40
Effects of active and passive smoking on the development of cardiovascular disease as assessed by a carotid intima-media thickness examination in patients with type 2 diabetes mellitus. Clin Exp Pharmacol Physiol (2015) 1.38
A novel eIF5A complex functions as a regulator of p53 and p53-dependent apoptosis. J Biol Chem (2004) 1.37
Passive smoking and risk of peripheral arterial disease and ischemic stroke in Chinese women who never smoked. Circulation (2008) 1.36
Transposition-driven genomic heterogeneity in the Drosophila brain. Science (2013) 1.35
CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer. Tumour Biol (2014) 1.34
Chlamydia vaccine candidates and tools for chlamydial antigen discovery. Expert Rev Vaccines (2009) 1.34
Effects of GCK, GCKR, G6PC2 and MTNR1B variants on glucose metabolism and insulin secretion. PLoS One (2010) 1.33
Upregulation of the long noncoding RNA TUG1 promotes proliferation and migration of esophageal squamous cell carcinoma. Tumour Biol (2014) 1.32
Infectious Disease: Connecting Innate Immunity to Biocidal Polymers. Mater Sci Eng R Rep (2007) 1.30
De novo designed synthetic mimics of antimicrobial peptides. Curr Opin Biotechnol (2008) 1.30
Synthetic antimicrobial oligomers induce a composition-dependent topological transition in membranes. J Am Chem Soc (2007) 1.29
Probing alpha-helical and beta-sheet structures of peptides at solid/liquid interfaces with SFG. Langmuir (2005) 1.29
Genome-wide association study identifies three novel loci for type 2 diabetes. Hum Mol Genet (2013) 1.28
Cationic nanoparticles induce nanoscale disruption in living cell plasma membranes. J Phys Chem B (2009) 1.27
A novel DNMT3B subfamily, DeltaDNMT3B, is the predominant form of DNMT3B in non-small cell lung cancer. Int J Oncol (2006) 1.27
Frequent and asymptomatic oropharyngeal shedding of human herpesvirus 8 among immunocompetent men. J Infect Dis (2006) 1.27
Relationship between genetic polymorphisms of ALDH2 and ADH1B and esophageal cancer risk: a meta-analysis. World J Gastroenterol (2010) 1.26
Intraperitoneal therapy for peritoneal cancer. Future Oncol (2010) 1.25
Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties. Biomacromolecules (2008) 1.25
NPInter: the noncoding RNAs and protein related biomacromolecules interaction database. Nucleic Acids Res (2006) 1.24
Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens. Antimicrob Agents Chemother (2007) 1.24
Variants from GIPR, TCF7L2, DGKB, MADD, CRY2, GLIS3, PROX1, SLC30A8 and IGF1 are associated with glucose metabolism in the Chinese. PLoS One (2010) 1.23
Pharmacologic inhibition of CDK4/6: mechanistic evidence for selective activity or acquired resistance in acute myeloid leukemia. Blood (2007) 1.23
Potential clinical significance of a plasma-based KRAS mutation analysis in patients with advanced non-small cell lung cancer. Clin Cancer Res (2010) 1.23
Synthetic mimics of antimicrobial peptides. Biopolymers (2008) 1.22
A proteome reference map and proteomic analysis of Bifidobacterium longum NCC2705. Mol Cell Proteomics (2006) 1.22
A proteomic analysis of cold stress responses in rice seedlings. Proteomics (2005) 1.22
Genome-wide identification of Chlamydia trachomatis antigens associated with tubal factor infertility. Fertil Steril (2011) 1.21
Chinese guidelines for the secondary prevention of ischemic stroke and transient ischemic attack 2010. CNS Neurosci Ther (2012) 1.20
Diagnosis and surgical treatment of solid pseudopapillary neoplasm of the pancreas: analysis of 24 cases. Can J Surg (2011) 1.20
Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids. Proc Natl Acad Sci U S A (2008) 1.20
The rediscovery of ancient Chinese herbal formulas. Phytother Res (2004) 1.20
A methodological, systematic review of evidence-based independent risk factors for surgical site infections after spinal surgery. Eur Spine J (2012) 1.17
Interactions between cells with distinct mutations in c-MYC and Pten in prostate cancer. PLoS Genet (2009) 1.16
Multiple orientation of melittin inside a single lipid bilayer determined by combined vibrational spectroscopic studies. J Am Chem Soc (2007) 1.16
A randomized phase 3 trial comparing pemetrexed/carboplatin and docetaxel/carboplatin as first-line treatment for advanced, nonsquamous non-small cell lung cancer. J Thorac Oncol (2011) 1.16
Ethyl 2-(4-chloro-phenyl)-3-(2,4-di-fluoro-phenoxy)acrylate. Acta Crystallogr Sect E Struct Rep Online (2008) 1.15
Balloon kyphoplasty versus percutaneous vertebroplasty in treating osteoporotic vertebral compression fracture: grading the evidence through a systematic review and meta-analysis. Eur Spine J (2012) 1.14
Identification of cis regulatory features in the embryonic zebrafish genome through large-scale profiling of H3K4me1 and H3K4me3 binding sites. Dev Biol (2011) 1.14
Ehd4 encodes a novel and Oryza-genus-specific regulator of photoperiodic flowering in rice. PLoS Genet (2013) 1.13
Detection and clinical significance of intratumoral EGFR mutational heterogeneity in Chinese patients with advanced non-small cell lung cancer. PLoS One (2013) 1.13