Giorgio Trinchieri

Author PubWeight™ 165.73‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Plasmacytoid dendritic cells in immunity. Nat Immunol 2004 9.11
2 Commensal bacteria control cancer response to therapy by modulating the tumor microenvironment. Science 2013 5.09
3 Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat Immunol 2006 5.00
4 Reciprocal activating interaction between natural killer cells and dendritic cells. J Exp Med 2002 4.67
5 Adenoma-linked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth. Nature 2012 4.41
6 Compartmentalized control of skin immunity by resident commensals. Science 2012 4.19
7 The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J Exp Med 2002 3.91
8 Interferon alpha/beta and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. J Exp Med 2002 3.86
9 A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J Exp Med 2005 3.59
10 Interferon-γ links ultraviolet radiation to melanomagenesis in mice. Nature 2011 3.56
11 Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med 2003 3.41
12 Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J Immunol 2003 3.17
13 Cancer classification using the Immunoscore: a worldwide task force. J Transl Med 2012 2.88
14 Interleukin-12 in anti-tumor immunity and immunotherapy. Cytokine Growth Factor Rev 2002 2.86
15 Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection. Cancer Res 2005 2.83
16 The immune score as a new possible approach for the classification of cancer. J Transl Med 2012 2.79
17 Interaction between conventional dendritic cells and natural killer cells is integral to the activation of effective antiviral immunity. Nat Immunol 2005 2.72
18 Plasmacytoid dendritic cells mediate oral tolerance. Immunity 2008 2.66
19 Innate immune mechanisms of colitis and colitis-associated colorectal cancer. Nat Rev Immunol 2010 2.58
20 MyD88-mediated signaling prevents development of adenocarcinomas of the colon: role of interleukin 18. J Exp Med 2010 2.57
21 Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med 2005 2.53
22 Recommendations from the iSBTc-SITC/FDA/NCI Workshop on Immunotherapy Biomarkers. Clin Cancer Res 2011 2.44
23 The reciprocal interaction of NK cells with plasmacytoid or myeloid dendritic cells profoundly affects innate resistance functions. J Immunol 2005 2.43
24 Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells. J Exp Med 2008 2.41
25 Persistent decreases in blood plasmacytoid dendritic cell number and function despite effective highly active antiretroviral therapy and increased blood myeloid dendritic cells in HIV-infected individuals. J Immunol 2002 2.37
26 Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J Exp Med 2002 2.25
27 Production of type I interferons: plasmacytoid dendritic cells and beyond. J Exp Med 2005 2.14
28 Tumor-specific CD8+ T cells expressing interleukin-12 eradicate established cancers in lymphodepleted hosts. Cancer Res 2010 2.13
29 Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol 2006 2.11
30 Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88. J Immunol 2005 2.05
31 Recognition of double-stranded RNA by human toll-like receptor 3 and downstream receptor signaling requires multimerization and an acidic pH. J Biol Chem 2005 2.03
32 MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-alpha release and initiation of immune responses in vivo. J Immunol 2005 1.92
33 IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors. J Clin Invest 2011 1.90
34 NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. Immunity 2012 1.84
35 A systematic approach to biomarker discovery; preamble to "the iSBTc-FDA taskforce on immunotherapy biomarkers". J Transl Med 2008 1.77
36 TGF-β signaling in myeloid cells is required for tumor metastasis. Cancer Discov 2013 1.76
37 Cancer and inflammation: promise for biologic therapy. J Immunother 2010 1.72
38 Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement. J Immunol 2004 1.69
39 The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1 (SDF-1)/CXCL12. J Exp Med 2003 1.63
40 Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages. J Immunol 2011 1.58
41 Regulation of interleukin-12/interleukin-23 production and the T-helper 17 response in humans. Immunol Rev 2008 1.54
42 IL-1R-MyD88 signaling in keratinocyte transformation and carcinogenesis. J Exp Med 2012 1.48
43 Tumour escape from immune surveillance through dendritic cell inactivation. Semin Cancer Biol 2002 1.38
44 The pivotal role of IKKα in the development of spontaneous lung squamous cell carcinomas. Cancer Cell 2013 1.36
45 The proinflammatory myeloid cell receptor TREM-1 controls Kupffer cell activation and development of hepatocellular carcinoma. Cancer Res 2012 1.27
46 Interleukin-10 in viral diseases and cancer: exiting the labyrinth? Immunol Rev 2004 1.26
47 IL-10 or not IL-10: that is the question. Nat Immunol 2007 1.24
48 Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system? Nat Rev Immunol 2011 1.23
49 Ikaros is required for plasmacytoid dendritic cell differentiation. Blood 2006 1.22
50 Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation. J Clin Invest 2013 1.21
51 Immunologic and therapeutic synergy of IL-27 and IL-2: enhancement of T cell sensitization, tumor-specific CTL reactivity and complete regression of disseminated neuroblastoma metastases in the liver and bone marrow. J Immunol 2009 1.20
52 Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing. Mol Ther 2012 1.19
53 Cell proliferation and survival induced by Toll-like receptors is antagonized by type I IFNs. Proc Natl Acad Sci U S A 2007 1.19
54 TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production. J Exp Med 2007 1.17
55 Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. J Immunol 2013 1.15
56 TLR3 and Rig-like receptor on myeloid dendritic cells and Rig-like receptor on human NK cells are both mandatory for production of IFN-gamma in response to double-stranded RNA. J Immunol 2010 1.13
57 Molecular pathways: toll-like receptors in the tumor microenvironment--poor prognosis or new therapeutic opportunity. Clin Cancer Res 2012 1.09
58 Intraluminal containment of commensal outgrowth in the gut during infection-induced dysbiosis. Cell Host Microbe 2013 1.08
59 Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. Int Immunol 2005 1.07
60 Highlights of 10 years of immunology in Nature Reviews Immunology. Nat Rev Immunol 2011 1.06
61 Astrocytes as antigen-presenting cells: expression of IL-12/IL-23. J Neurochem 2005 1.05
62 Toll-like receptor signaling stimulates cell cycle entry and progression in fibroblasts. J Biol Chem 2005 1.05
63 The price of immunity. Nat Immunol 2012 1.04
64 Are dendritic cells afraid of commitment? Nat Immunol 2004 1.02
65 The human papillomavirus type 16 E7 oncoprotein induces a transcriptional repressor complex on the Toll-like receptor 9 promoter. J Exp Med 2013 1.01
66 OSCAR is an FcRgamma-associated receptor that is expressed by myeloid cells and is involved in antigen presentation and activation of human dendritic cells. Blood 2004 1.00
67 The role of the microbiota in inflammation, carcinogenesis, and cancer therapy. Eur J Immunol 2014 0.97
68 Distinct and overlapping roles of interleukin-10 and CD25+ regulatory T cells in the inhibition of antitumor CD8 T-cell responses. Cancer Res 2005 0.97
69 Future perspectives in melanoma research. Meeting report from the "Melanoma Bridge. Napoli, December 2nd-4th 2012". J Transl Med 2013 0.95
70 Oncogene-driven intrinsic inflammation induces leukocyte production of tumor necrosis factor that critically contributes to mammary carcinogenesis. Cancer Res 2010 0.91
71 Cell depletion in mice that express diphtheria toxin receptor under the control of SiglecH encompasses more than plasmacytoid dendritic cells. J Immunol 2014 0.90
72 The interleukin-12 and interleukin-12 receptor system in normal and transformed human B lymphocytes. Haematologica 2002 0.89
73 CD85j (leukocyte Ig-like receptor-1/Ig-like transcript 2) inhibits human osteoclast-associated receptor-mediated activation of human dendritic cells. J Immunol 2005 0.89
74 Interleukin-2 inhibits FMS-like tyrosine kinase 3 receptor ligand (flt3L)-dependent development and function of conventional and plasmacytoid dendritic cells. Proc Natl Acad Sci U S A 2011 0.89
75 MyD88 and its divergent toll in carcinogenesis. Trends Immunol 2013 0.88
76 Origin and filiation of human plasmacytoid dendritic cells. Hum Immunol 2002 0.87
77 IFN-gamma and IL-12 differentially regulate CC-chemokine secretion and CCR5 expression in human T lymphocytes. J Leukoc Biol 2002 0.86
78 CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues. Blood 2011 0.86
79 Ligation of the FcR gamma chain-associated human osteoclast-associated receptor enhances the proinflammatory responses of human monocytes and neutrophils. J Immunol 2006 0.86
80 Reinforcing suppression using regulators: a new link between STAT3, IL-23, and Tregs in tumor immunosuppression. Cancer Cell 2009 0.84
81 CSF-1R, DAP12 and beta-catenin: a ménage à trois. Nat Immunol 2009 0.83
82 Effect of the V3 loop deletion of envelope glycoprotein on cellular responses and protection against challenge with recombinant vaccinia virus expressing gp160 of primary human immunodeficiency virus type 1 isolates. J Virol 2002 0.83
83 Virus overrides the propensity of human CD40L-activated plasmacytoid dendritic cells to produce Th2 mediators through synergistic induction of IFN-{gamma} and Th1 chemokine production. J Leukoc Biol 2005 0.83
84 In vivo manipulation of dendritic cell migration and activation to elicit antitumour immunity. Novartis Found Symp 2004 0.82
85 Fc receptor gamma-chain activation via hOSCAR induces survival and maturation of dendritic cells and modulates Toll-like receptor responses. Blood 2005 0.82
86 LAB/NTAL facilitates fungal/PAMP-induced IL-12 and IFN-γ production by repressing β-catenin activation in dendritic cells. PLoS Pathog 2013 0.81
87 The choices of a natural killer. Nat Immunol 2003 0.79
88 National Institutes of Health Center for Human Immunology Conference, September 2009. Ann N Y Acad Sci 2010 0.79
89 Double stranded RNA tricks melanoma cells into committing suicide. Pigment Cell Melanoma Res 2009 0.78
90 At 17, in-10's passion need not inflame. Immunity 2011 0.77
91 Innate resistance and inflammation. Curr Opin Immunol 2009 0.76