Published in Emerg Infect Dis on January 01, 2006
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis (2008) 11.01
The genomic and epidemiological dynamics of human influenza A virus. Nature (2008) 10.26
Influenza pandemics of the 20th century. Emerg Infect Dis (2006) 7.19
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature (2006) 6.46
Avian influenza virus (H5N1): a threat to human health. Clin Microbiol Rev (2007) 6.38
Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus. Science (2010) 6.10
The pathology of influenza virus infections. Annu Rev Pathol (2008) 5.37
Mortality from pandemic A/H1N1 2009 influenza in England: public health surveillance study. BMJ (2009) 4.99
H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog (2008) 4.79
Dating the emergence of pandemic influenza viruses. Proc Natl Acad Sci U S A (2009) 4.36
Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections. Arch Pathol Lab Med (2010) 3.91
TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci U S A (2009) 3.70
The persistent legacy of the 1918 influenza virus. N Engl J Med (2009) 3.58
BioHealthBase: informatics support in the elucidation of influenza virus host pathogen interactions and virulence. Nucleic Acids Res (2007) 3.28
Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918. PLoS Pathog (2008) 3.25
Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines. PLoS Pathog (2010) 3.08
Cross-neutralization of 1918 and 2009 influenza viruses: role of glycans in viral evolution and vaccine design. Sci Transl Med (2010) 3.06
Early assessment of anxiety and behavioral response to novel swine-origin influenza A(H1N1). PLoS One (2009) 2.80
Severe pandemic 2009 H1N1 influenza disease due to pathogenic immune complexes. Nat Med (2010) 2.59
A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection. Cell (2013) 2.38
Risk of severe outcomes among patients admitted to hospital with pandemic (H1N1) influenza. CMAJ (2010) 2.36
Discovery and characterization of the 1918 pandemic influenza virus in historical context. Antivir Ther (2007) 2.32
Cross-protection between successive waves of the 1918-1919 influenza pandemic: epidemiological evidence from US Army camps and from Britain. J Infect Dis (2008) 2.29
Pandemic influenza--including a risk assessment of H5N1. Rev Sci Tech (2009) 2.27
Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential. Cell Host Microbe (2014) 2.15
Towards a sane and rational approach to management of Influenza H1N1 2009. Virol J (2009) 2.08
Proteolytic activation of the 1918 influenza virus hemagglutinin. J Virol (2009) 2.05
Virulence determinants of pandemic influenza viruses. J Clin Invest (2011) 1.87
The next influenza pandemic: can it be predicted? JAMA (2007) 1.86
Predicting 'airborne' influenza viruses: (trans-) mission impossible? Curr Opin Virol (2011) 1.83
Different evolutionary trajectories of European avian-like and classical swine H1N1 influenza A viruses. J Virol (2009) 1.79
2009 H1N1 influenza. Mayo Clin Proc (2009) 1.76
Time variations in the transmissibility of pandemic influenza in Prussia, Germany, from 1918-19. Theor Biol Med Model (2007) 1.74
Quantifying social distancing arising from pandemic influenza. J R Soc Interface (2008) 1.70
Pandemic influenza (H1N1) 2009 is associated with severe disease in India. PLoS One (2010) 1.68
Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak. Proc Natl Acad Sci U S A (2011) 1.67
The shifting demographic landscape of pandemic influenza. PLoS One (2010) 1.66
Real-time epidemic forecasting for pandemic influenza. Epidemiol Infect (2006) 1.66
Domestic pigs have low susceptibility to H5N1 highly pathogenic avian influenza viruses. PLoS Pathog (2008) 1.66
Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease. J Neuropathol Exp Neurol (2009) 1.66
Influenza: the once and future pandemic. Public Health Rep (2010) 1.65
Homologous recombination is very rare or absent in human influenza A virus. J Virol (2008) 1.63
Immuno-epidemiologic correlates of pandemic H1N1 surveillance observations: higher antibody and lower cell-mediated immune responses with advanced age. J Infect Dis (2011) 1.61
Novel swine-origin influenza A virus in humans: another pandemic knocking at the door. Med Microbiol Immunol (2009) 1.60
Understanding influenza transmission, immunity and pandemic threats. Influenza Other Respir Viruses (2009) 1.60
Deaths associated with influenza pandemic of 1918-19, Japan. Emerg Infect Dis (2013) 1.59
Influenza pandemics in Singapore, a tropical, globally connected city. Emerg Infect Dis (2007) 1.54
Pandemic and seasonal influenza: therapeutic challenges. Drug Discov Today (2008) 1.54
Role of sialic acid binding specificity of the 1918 influenza virus hemagglutinin protein in virulence and pathogenesis for mice. J Virol (2009) 1.53
The emergence of pandemic influenza viruses. Protein Cell (2010) 1.52
Comparative age distribution of influenza morbidity and mortality during seasonal influenza epidemics and the 2009 H1N1 pandemic. BMC Infect Dis (2010) 1.48
Progress in identifying virulence determinants of the 1918 H1N1 and the Southeast Asian H5N1 influenza A viruses. Antiviral Res (2008) 1.47
The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions. PLoS One (2012) 1.47
Infection fatality risk of the pandemic A(H1N1)2009 virus in Hong Kong. Am J Epidemiol (2013) 1.47
Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection. Nat Immunol (2013) 1.47
Synthetic viruses: a new opportunity to understand and prevent viral disease. Nat Biotechnol (2009) 1.47
The evolution of human influenza A viruses from 1999 to 2006: a complete genome study. Virol J (2008) 1.45
Predictors of clinical outcome in a national hospitalised cohort across both waves of the influenza A/H1N1 pandemic 2009-2010 in the UK. Thorax (2012) 1.40
Pandemic influenza: certain uncertainties. Rev Med Virol (2011) 1.39
pH1N1 influenza A: timing is everything. Crit Care Med (2010) 1.38
An early 'classical' swine H1N1 influenza virus shows similar pathogenicity to the 1918 pandemic virus in ferrets and mice. Virology (2009) 1.37
The changing face of pathogen discovery and surveillance. Nat Rev Microbiol (2013) 1.37
The 1918 influenza pandemic: lessons for 2009 and the future. Crit Care Med (2010) 1.36
Developing guidelines for school closure interventions to be used during a future influenza pandemic. BMC Infect Dis (2010) 1.36
Mortality burden of the 1918-1919 influenza pandemic in Europe. Influenza Other Respir Viruses (2009) 1.35
Reconstruction of the 1918 influenza virus: unexpected rewards from the past. MBio (2012) 1.34
Cryptococcus neoformans mates on pigeon guano: implications for the realized ecological niche and globalization. Eukaryot Cell (2007) 1.33
Effectiveness and cost-effectiveness of expanded antiviral prophylaxis and adjuvanted vaccination strategies for an influenza A (H5N1) pandemic. Ann Intern Med (2009) 1.33
Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein. PLoS One (2009) 1.30
Experimental infection of pigs with the human 1918 pandemic influenza virus. J Virol (2009) 1.29
Mortality burden of the 2009 A/H1N1 influenza pandemic in France: comparison to seasonal influenza and the A/H3N2 pandemic. PLoS One (2012) 1.29
The ability of pandemic influenza virus hemagglutinins to induce lower respiratory pathology is associated with decreased surfactant protein D binding. Virology (2011) 1.25
Inference of seasonal and pandemic influenza transmission dynamics. Proc Natl Acad Sci U S A (2015) 1.25
Highly sensitive real-time in vivo imaging of an influenza reporter virus reveals dynamics of replication and spread. J Virol (2013) 1.23
Pathogenic responses among young adults during the 1918 influenza pandemic. Emerg Infect Dis (2012) 1.22
Traditional and new influenza vaccines. Clin Microbiol Rev (2013) 1.22
Quantification of excess risk for diabetes for those born in times of hunger, in an entire population of a nation, across a century. Proc Natl Acad Sci U S A (2013) 1.19
The PB2-E627K mutation attenuates viruses containing the 2009 H1N1 influenza pandemic polymerase. MBio (2010) 1.18
Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus. Proc Natl Acad Sci U S A (2014) 1.17
Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies. Proc Natl Acad Sci U S A (2013) 1.17
Infectious disease emergence and global change: thinking systemically in a shrinking world. Infect Dis Poverty (2012) 1.17
Conserved amino acid markers from past influenza pandemic strains. BMC Microbiol (2009) 1.16
Understanding influenza backward. JAMA (2009) 1.15
Prior immunity helps to explain wave-like behaviour of pandemic influenza in 1918-9. BMC Infect Dis (2010) 1.14
The new influenza A H1N1 virus: balancing on the interface of humans and animals. Can Vet J (2010) 1.12
Explaining rapid reinfections in multiple-wave influenza outbreaks: Tristan da Cunha 1971 epidemic as a case study. Proc Biol Sci (2011) 1.10
Comparison of pro-inflammatory cytokine expression and cellular signal transduction in human macrophages infected with different influenza A viruses. Med Microbiol Immunol (2010) 1.09
Connecting the study of wild influenza with the potential for pandemic disease. Infect Genet Evol (2013) 1.08
Maximizing the value of drug stockpiles for pandemic influenza. Emerg Infect Dis (2009) 1.08
Stockpiling drugs for an avian influenza outbreak: examining the surge in oseltamivir prescriptions during heightened media coverage of the potential for a worldwide pandemic. Infect Control Hosp Epidemiol (2009) 1.08
Host adaptation and transmission of influenza A viruses in mammals. Emerg Microbes Infect (2014) 1.06
Higher polymerase activity of a human influenza virus enhances activation of the hemagglutinin-induced Raf/MEK/ERK signal cascade. Virol J (2007) 1.05
The relationship between tuberculosis and influenza death during the influenza (H1N1) pandemic from 1918-19. Comput Math Methods Med (2012) 1.05
Population-level effects of suppressing fever. Proc Biol Sci (2014) 1.05
Inflammatory effects of highly pathogenic H5N1 influenza virus infection in the CNS of mice. J Neurosci (2012) 1.05
Managing public health crises: the role of models in pandemic preparedness. Influenza Other Respir Viruses (2009) 1.04
Spanish influenza in Japanese armed forces, 1918-1920. Emerg Infect Dis (2007) 1.04
Dimer interface of the effector domain of non-structural protein 1 from influenza A virus: an interface with multiple functions. J Biol Chem (2011) 1.03
Immunization with 1976 swine H1N1- or 2009 pandemic H1N1-inactivated vaccines protects mice from a lethal 1918 influenza infection. Influenza Other Respir Viruses (2011) 1.02
Characterization of the 1918 influenza virus polymerase genes. Nature (2005) 15.73
Updating the accounts: global mortality of the 1918-1920 "Spanish" influenza pandemic. Bull Hist Med (2002) 11.85
Initial genetic characterization of the 1918 "Spanish" influenza virus. Science (1997) 10.17
Re-emergence of fatal human influenza A subtype H5N1 disease. Lancet (2004) 9.36
THE INCIDENCE OF NEUTRALIZING ANTIBODIES FOR SWINE INFLUENZA VIRUS IN THE SERA OF HUMAN BEINGS OF DIFFERENT AGES. J Exp Med (1936) 8.52
Pandemic versus epidemic influenza mortality: a pattern of changing age distribution. J Infect Dis (1998) 8.51
Origin and evolution of the 1918 "Spanish" influenza virus hemagglutinin gene. Proc Natl Acad Sci U S A (1999) 8.40
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature (1988) 8.32
Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature (2004) 6.11
The geography and mortality of the 1918 influenza pandemic. Bull Hist Med (1991) 5.15
Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site. Virology (1997) 4.96
Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proc Natl Acad Sci U S A (2001) 4.93
A single amino acid substitution in 1918 influenza virus hemagglutinin changes receptor binding specificity. J Virol (2005) 4.71
Characterization of the 1918 "Spanish" influenza virus neuraminidase gene. Proc Natl Acad Sci U S A (2000) 3.67
Evolution of the H3 influenza virus hemagglutinin from human and nonhuman hosts. J Virol (1992) 3.37
Evidence of an absence: the genetic origins of the 1918 pandemic influenza virus. Nat Rev Microbiol (2004) 3.19
World War I may have allowed the emergence of "Spanish" influenza. Lancet Infect Dis (2002) 2.88
Antigenic similarity of influenza A (H1N1) viruses from epidemics in 1977--1978 to "Scandinavian" strains isolated in epidemics of 1950--1951. Virology (1978) 2.61
Novel origin of the 1918 pandemic influenza virus nucleoprotein gene. J Virol (2004) 2.55
1918 influenza pandemic caused by highly conserved viruses with two receptor-binding variants. Emerg Infect Dis (2003) 2.32
Characterization of the 1918 "Spanish" influenza virus matrix gene segment. J Virol (2002) 2.05
The 1918 influenza virus: A killer comes into view. Virology (2000) 1.94
The 1918 flu and other influenza pandemics: "over there" and back again. Lab Invest (1999) 1.74
1917 avian influenza virus sequences suggest that the 1918 pandemic virus did not acquire its hemagglutinin directly from birds. J Virol (2002) 1.60
Relationship of pre-1918 avian influenza HA and NP sequences to subsequent avian influenza strains. Avian Dis (2003) 1.33
The pathology of influenza virus infections. Annu Rev Pathol (2008) 5.37
Cross-species virus transmission and the emergence of new epidemic diseases. Microbiol Mol Biol Rev (2008) 4.46
Pulmonary pathologic findings of fatal 2009 pandemic influenza A/H1N1 viral infections. Arch Pathol Lab Med (2010) 3.91
Zika Virus in the Americas--Yet Another Arbovirus Threat. N Engl J Med (2016) 3.78
The perpetual challenge of infectious diseases. N Engl J Med (2012) 3.77
Discovery and characterization of the 1918 pandemic influenza virus in historical context. Antivir Ther (2007) 2.32
Age- and sex-specific mortality associated with the 1918-1919 influenza pandemic in Kentucky. J Infect Dis (2012) 1.95
The next influenza pandemic: can it be predicted? JAMA (2007) 1.86
Autopsy series of 68 cases dying before and during the 1918 influenza pandemic peak. Proc Natl Acad Sci U S A (2011) 1.67
Influenza: the once and future pandemic. Public Health Rep (2010) 1.65
Pandemic and seasonal influenza: therapeutic challenges. Drug Discov Today (2008) 1.54
Reconstruction of the 1918 influenza virus: unexpected rewards from the past. MBio (2012) 1.34
Prior infection with classical swine H1N1 influenza viruses is associated with protective immunity to the 2009 pandemic H1N1 virus. Influenza Other Respir Viruses (2010) 1.25
Dengue research opportunities in the Americas. J Infect Dis (2012) 1.22
Protection against a lethal H5N1 influenza challenge by intranasal immunization with virus-like particles containing 2009 pandemic H1N1 neuraminidase in mice. Virology (2012) 1.16
Bacterial pathogens and death during the 1918 influenza pandemic. N Engl J Med (2009) 1.14
Influenza viruses: breaking all the rules. MBio (2013) 1.14
Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic. J Infect Dis (2010) 1.11
Editorial commentary: pandemic H5N1: receding risk or coming catastrophe? Clin Infect Dis (2013) 1.02
1918 influenza, a puzzle with missing pieces. Emerg Infect Dis (2012) 0.95
Influenza revisited. Emerg Infect Dis (2006) 0.94
Reappraisal of the association of intussusception with the licensed live rotavirus vaccine challenges initial conclusions. J Infect Dis (2003) 0.91
Variant Creutzfeldt-Jakob disease and the acquired and transmissible spongiform encephalopathies. Clin Infect Dis (2004) 0.90
A hexavalent human rotavirus-bovine rotavirus (UK) reassortant vaccine designed for use in developing countries and delivered in a schedule with the potential to eliminate the risk of intussusception. J Infect Dis (2005) 0.89
The role of radiology in influenza: novel H1N1 and lessons learned from the 1918 pandemic. J Am Coll Radiol (2010) 0.85
Influenza-related mortality: considerations for practice and public health. JAMA (2003) 0.84
Influenza in pregnancy. Influenza Other Respir Viruses (2012) 0.81
Fatal 1918 pneumonia case complicated by erythrocyte sickling. Emerg Infect Dis (2010) 0.78
Eyewitness accounts of the 1510 influenza pandemic in Europe. Lancet (2010) 0.78
Ecological studies, rotavirus vaccination, and intussusception. Lancet (2002) 0.75
Reply to "'BUt nature started it': examining Taubenberger and Morens' view on influenza a virus and dual-use research of concern". MBio (2013) 0.75
The Past Is Never Dead— Measles Epidemic, Boston, Massachusetts, 1713. Emerg Infect Dis (2015) 0.75
In Memoriam: Robert M. Chanock, MD, 1924–2010. J Infect Dis (2011) 0.75