Published in PLoS One on January 23, 2012
Pneumonia in low and middle income countries: progress and challenges. Thorax (2013) 1.21
Influenza and RSV make a modest contribution to invasive pneumococcal disease incidence in the UK. J Infect (2013) 0.90
The role of influenza in the severity and transmission of respiratory bacterial disease. Lancet Respir Med (2014) 0.83
Time and dose-dependent risk of pneumococcal pneumonia following influenza: a model for within-host interaction between influenza and Streptococcus pneumoniae. J R Soc Interface (2013) 0.83
Severity of influenza A 2009 (H1N1) pneumonia is underestimated by routine prediction rules. Results from a prospective, population-based study. PLoS One (2012) 0.82
Dynamic modeling for pandemic influenza. Expert Rev Vaccines (2012) 0.78
Strategies for containing an emerging influenza pandemic in Southeast Asia. Nature (2005) 30.92
Strategies for mitigating an influenza pandemic. Nature (2006) 25.20
Transmissibility of 1918 pandemic influenza. Nature (2004) 16.14
1918 Influenza: the mother of all pandemics. Emerg Infect Dis (2006) 12.11
Predominant role of bacterial pneumonia as a cause of death in pandemic influenza: implications for pandemic influenza preparedness. J Infect Dis (2008) 11.01
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature (2007) 10.40
Time lines of infection and disease in human influenza: a review of volunteer challenge studies. Am J Epidemiol (2008) 10.02
Population biology of infectious diseases: Part I. Nature (1979) 9.66
Sustained reductions in invasive pneumococcal disease in the era of conjugate vaccine. J Infect Dis (2010) 8.37
PNEUMOCOCCAL BACTEREMIA WITH ESPECIAL REFERENCE TO BACTEREMIC PNEUMOCOCCAL PNEUMONIA. Ann Intern Med (1964) 7.18
Influenza-associated deaths among children in the United States, 2003-2004. N Engl J Med (2005) 6.83
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature (2006) 6.46
Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature (2004) 6.11
A CONTRIBUTION TO THE EPIDEMIOLOGY OF LOBAR PNEUMONIA. J Exp Med (1916) 4.95
Incidence of community-acquired pneumonia requiring hospitalization. Results of a population-based active surveillance Study in Ohio. The Community-Based Pneumonia Incidence Study Group. Arch Intern Med (1997) 4.84
Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. Pediatrics (2004) 4.74
Epidemiological evidence of an early wave of the 1918 influenza pandemic in New York City. Proc Natl Acad Sci U S A (2005) 4.29
Lethal synergism between influenza virus and Streptococcus pneumoniae: characterization of a mouse model and the role of platelet-activating factor receptor. J Infect Dis (2002) 4.21
Family studies of respiratory infections. Br Med J (1958) 4.02
An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clin Infect Dis (2003) 3.93
Deaths from bacterial pneumonia during 1918-19 influenza pandemic. Emerg Infect Dis (2008) 3.92
Interactions between influenza and bacterial respiratory pathogens: implications for pandemic preparedness. Lancet Infect Dis (2006) 3.74
A role for Streptococcus pneumoniae in virus-associated pneumonia. Nat Med (2004) 3.49
The "cloud baby": an example of bacterial-viral interaction. Am J Dis Child (1960) 3.32
Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian villagers. Clin Infect Dis (2006) 2.96
Nasopharyngeal carriage of Streptococcus pneumoniae in Finnish children younger than 2 years old. J Infect Dis (2001) 2.83
Influenza enhances susceptibility to natural acquisition of and disease due to Streptococcus pneumoniae in ferrets. J Infect Dis (2010) 2.77
A cloud adult: the Staphylococcus aureus-virus interaction revisited. Ann Intern Med (1996) 2.66
Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza. PLoS One (2009) 2.65
The genesis and spread of reassortment human influenza A/H3N2 viruses conferring adamantane resistance. Mol Biol Evol (2007) 2.59
Respiratory viruses predisposing to bacterial infections: role of neuraminidase. Pediatr Infect Dis J (2004) 2.53
Bacteriology and histopathology of the respiratory tract and lungs in fatal Asian influenza. Lancet (1958) 2.50
Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States. MBio (2011) 2.48
A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. Epidemiol Infect (2005) 2.32
The descriptive epidemiology of Streptococcus pneumoniae and Haemophilus influenzae nasopharyngeal carriage in children and adults in Kilifi district, Kenya. Pediatr Infect Dis J (2008) 2.23
Spread of Streptococcus pneumoniae in families. II. Relation of transfer of S. pneumoniae to incidence of colds and serum antibody. J Infect Dis (1975) 2.05
Nasopharyngeal carriage of Streptococcus pneumoniae by adults and children in community and family settings. Clin Infect Dis (2004) 1.95
FURTHER STUDIES ON THE EPIDEMIOLOGY OF LOBAR PNEUMONIA. J Exp Med (1917) 1.80
Pneumococcal pneumonia and influenza: a deadly combination. Vaccine (2009) 1.78
Prioritization of influenza pandemic vaccination to minimize years of life lost. J Infect Dis (2008) 1.69
Age- and serogroup-related differences in observed durations of nasopharyngeal carriage of penicillin-resistant pneumococci. J Clin Microbiol (2007) 1.68
Streptococcus pneumoniae: epidemiology, risk factors, and strategies for prevention. Semin Respir Crit Care Med (2009) 1.67
Effect of short-course, high-dose amoxicillin therapy on resistant pneumococcal carriage: a randomized trial. JAMA (2001) 1.64
Impact of a conjugate vaccine on community-wide carriage of nonsusceptible Streptococcus pneumoniae in Alaska. J Infect Dis (2004) 1.43
Dispersal of Staphylococcus aureus into the air associated with a rhinovirus infection. Infect Control Hosp Epidemiol (2005) 1.15
Bacterial pathogens and death during the 1918 influenza pandemic. N Engl J Med (2009) 1.14
Serotypes and genotypes of Streptococcus pneumoniae causing pneumonia and acute exacerbations in patients with chronic obstructive pulmonary disease. J Antimicrob Chemother (2010) 1.12
Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic. J Infect Dis (2010) 1.11
A comparison of clinical and epidemiological characteristics of fatal human infections with H5N1 and human influenza viruses in Thailand, 2004-2006. PLoS One (2011) 1.11
Time from illness onset to death, 1918 influenza and pneumococcal pneumonia. Emerg Infect Dis (2009) 1.00
What really happened during the 1918 influenza pandemic? The importance of bacterial secondary infections. J Infect Dis (2007) 0.96
The epidemiology of community-acquired pneumonia among hospitalized adults. J Infect (1997) 0.94
Nasal carriage of Streptococcus pneumoniae in healthy children and adults in northern Taiwan. Diagn Microbiol Infect Dis (2007) 0.83
Public health and economic impact of vaccination with 7-valent pneumococcal vaccine (PCV7) in the context of the annual influenza epidemic and a severe influenza pandemic. BMC Infect Dis (2010) 0.83
SOME ASPECTS of the recent epidemic of influenza in Dundee. Br Med J (1958) 0.83
Adventures with antibacterial drugs. Clin Pharmacol Ther (1972) 0.78
The prevalence of colonization with drug-resistant pneumococci among adult workers in children's daycare. Ear Nose Throat J (2007) 0.77
Rapid pneumococcal evolution in response to clinical interventions. Science (2011) 9.09
Antimicrobial resistance in developing countries. Part I: recent trends and current status. Lancet Infect Dis (2005) 5.58
Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet (2011) 5.43
International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections. Ann Intern Med (2004) 4.75
Biological and biomedical implications of the co-evolution of pathogens and their hosts. Nat Genet (2002) 4.42
Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns. Emerg Infect Dis (2002) 4.08
An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clin Infect Dis (2003) 3.93
Antiviral resistance and the control of pandemic influenza. PLoS Med (2007) 3.92
Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. Clin Infect Dis (2004) 3.75
Epidemiological differences among pneumococcal serotypes. Lancet Infect Dis (2005) 3.72
Influenza vaccination of pregnant women and protection of their infants. N Engl J Med (2014) 3.68
Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia. Am J Respir Crit Care Med (2004) 3.49
A role for Streptococcus pneumoniae in virus-associated pneumonia. Nat Med (2004) 3.49
The impact of a 9-valent pneumococcal conjugate vaccine on the public health burden of pneumonia in HIV-infected and -uninfected children. Clin Infect Dis (2005) 2.81
Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis (2010) 2.50
Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections. Emerg Infect Dis (2007) 2.49
Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States. MBio (2011) 2.48
Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children. Pediatr Infect Dis J (2013) 2.47
Pneumococcal vaccination in developing countries. Lancet (2006) 2.45
Functional relationship between bacterial cell density and the efficacy of antibiotics. J Antimicrob Chemother (2009) 2.24
Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus. Antimicrob Agents Chemother (2005) 2.14
Impact of conjugate pneumococcal vaccines on antibiotic resistance. Lancet Infect Dis (2008) 2.11
Ineffectiveness of trimethoprim-sulfamethoxazole prophylaxis and the importance of bacterial and viral coinfections in African children with Pneumocystis carinii pneumonia. Clin Infect Dis (2002) 2.07
Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies. Vaccine (2007) 2.07
Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States. Pediatr Infect Dis J (2007) 2.06
Antimicrobial resistance in developing countries. Part II: strategies for containment. Lancet Infect Dis (2005) 2.05
Increased prevalence of pediatric pneumococcal serotypes in elderly adults. Clin Infect Dis (2005) 2.03
Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae. Antimicrob Agents Chemother (2006) 1.98
Dealing with the evolutionary downside of CRISPR immunity: bacteria and beneficial plasmids. PLoS Genet (2013) 1.97
Pharmacodynamic functions: a multiparameter approach to the design of antibiotic treatment regimens. Antimicrob Agents Chemother (2004) 1.93
Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis. J Infect Dis (2009) 1.92
Effects of vaccination on invasive pneumococcal disease in South Africa. N Engl J Med (2014) 1.84
Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination. J Infect Dis (2009) 1.82
Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis. Lancet Infect Dis (2010) 1.82
Maternal influenza immunization and reduced likelihood of prematurity and small for gestational age births: a retrospective cohort study. PLoS Med (2011) 1.82
Emergence and spread of Streptococcus pneumoniae with erm(B) and mef(A) resistance. Emerg Infect Dis (2005) 1.74
Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance. Clin Infect Dis (2009) 1.69
Modeling the role of bacteriophage in the control of cholera outbreaks. Proc Natl Acad Sci U S A (2006) 1.68
Hypermutation and the preexistence of antibiotic-resistant Pseudomonas aeruginosa mutants: implications for susceptibility testing and treatment of chronic infections. Antimicrob Agents Chemother (2004) 1.67
Historical changes in pneumococcal serogroup distribution: implications for the era of pneumococcal conjugate vaccines. Clin Infect Dis (2002) 1.66
Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003. Clin Infect Dis (2011) 1.63
The evolution of mutator genes in bacterial populations: the roles of environmental change and timing. Genetics (2003) 1.58
Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine. Antimicrob Agents Chemother (2004) 1.53
Pneumococcal vaccines and flu preparedness. Science (2007) 1.50
Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in a South African child in a tuberculosis treatment facility. Pediatr Infect Dis J (2003) 1.44
Grazing protozoa and the evolution of the Escherichia coli O157:H7 Shiga toxin-encoding prophage. Proc Biol Sci (2007) 1.44
The ecology of nasal colonization of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus: the role of competition and interactions with host's immune response. BMC Microbiol (2010) 1.44
Pneumococcal capsular switching: a historical perspective. J Infect Dis (2012) 1.43
Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South Africa. Int J Antimicrob Agents (2008) 1.40
Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants. J Infect Dis (2010) 1.39
World Health Organisation definition of "radiologically-confirmed pneumonia" may under-estimate the true public health value of conjugate pneumococcal vaccines. Vaccine (2006) 1.38
Dynamics of success and failure in phage and antibiotic therapy in experimental infections. BMC Microbiol (2002) 1.36
Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin. Antimicrob Agents Chemother (2004) 1.36
Role of Streptococcus pneumoniae in hospitalization for acute community-acquired pneumonia associated with culture-confirmed Mycobacterium tuberculosis in children: a pneumococcal conjugate vaccine probe study. Pediatr Infect Dis J (2010) 1.33
Influence of bacterial interactions on pneumococcal colonization of the nasopharynx. Trends Microbiol (2012) 1.33
Quantitative and qualitative antibody response to pneumococcal conjugate vaccine among African human immunodeficiency virus-infected and uninfected children. Pediatr Infect Dis J (2005) 1.31
A framework for global surveillance of antibiotic resistance. Drug Resist Updat (2011) 1.29
Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice. MBio (2014) 1.26
Epidemiology of invasive pneumococcal disease among high-risk adults since the introduction of pneumococcal conjugate vaccine for children. Clin Infect Dis (2012) 1.26
Global epidemiology of invasive meningococcal disease. Popul Health Metr (2013) 1.25
Epidemiology of Group B Streptococcus in developing countries. Vaccine (2013) 1.24
Communicating trends in resistance using a drug resistance index. BMJ Open (2011) 1.23
Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus. PLoS Genet (2013) 1.23
Public health and economic impact of the 13-valent pneumococcal conjugate vaccine (PCV13) in the United States. Vaccine (2010) 1.23
Lower respiratory tract infections associated with influenza A and B viruses in an area with a high prevalence of pediatric human immunodeficiency type 1 infection. Pediatr Infect Dis J (2002) 1.22
Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa. PLoS One (2012) 1.21
Reduced effectiveness of Haemophilus influenzae type b conjugate vaccine in children with a high prevalence of human immunodeficiency virus type 1 infection. Pediatr Infect Dis J (2002) 1.19
The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis. AIDS (2011) 1.19
Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005. J Clin Microbiol (2008) 1.19
Analysis of penicillin-binding protein genes of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to amoxicillin. Antimicrob Agents Chemother (2002) 1.16
Seasonality, incidence, and repeat human metapneumovirus lower respiratory tract infections in an area with a high prevalence of human immunodeficiency virus type-1 infection. Pediatr Infect Dis J (2007) 1.16
In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae. Antimicrob Agents Chemother (2008) 1.16
Human metapneumovirus genetic variability, South Africa. Emerg Infect Dis (2005) 1.15
Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants. Clin Infect Dis (2003) 1.14
Bacterial pathogens and death during the 1918 influenza pandemic. N Engl J Med (2009) 1.14
Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children. Pediatr Infect Dis J (2003) 1.14
Antibiotics in agriculture: when is it time to close the barn door? Proc Natl Acad Sci U S A (2002) 1.13
Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic. J Infect Dis (2010) 1.11
Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South Africa. AIDS (2010) 1.11
Pneumococcal coinfection with human metapneumovirus. J Infect Dis (2006) 1.09
Within-host evolution for the invasiveness of commensal bacteria: an experimental study of bacteremias resulting from Haemophilus influenzae nasal carriage. J Infect Dis (2007) 1.09
Fluoroquinolone-resistant Streptococcus pneumoniae. Emerg Infect Dis (2006) 1.08
Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms. MBio (2013) 1.08
Persistent high burden of invasive pneumococcal disease in South African HIV-infected adults in the era of an antiretroviral treatment program. PLoS One (2011) 1.08
Recommendations for treatment of childhood non-severe pneumonia. Lancet Infect Dis (2009) 1.07
The relationship between pneumococcal serotypes and antibiotic resistance. Vaccine (2012) 1.07
The future of pneumococcal disease prevention. Vaccine (2011) 1.06
Two-drug antimicrobial chemotherapy: a mathematical model and experiments with Mycobacterium marinum. PLoS Pathog (2012) 1.06
Immunogenicity and effectiveness of Haemophilus influenzae type b conjugate vaccine in HIV infected and uninfected African children. Vaccine (2005) 1.06
Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones. J Antimicrob Chemother (2002) 1.05
The battle against emerging antibiotic resistance: should fluoroquinolones be used to treat children? Clin Infect Dis (2002) 1.04
Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008. Vaccine (2013) 1.04
Epidemiology, hypermutation, within-host evolution and the virulence of Neisseria meningitidis. Proc Biol Sci (2003) 1.04
Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents. J Antimicrob Chemother (2003) 1.03
Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone. BMC Biol (2014) 1.03
Vaccines as tools against resistance: the example of pneumococcal conjugate vaccine. Semin Pediatr Infect Dis (2004) 1.02