Published in Toxicol Sci on February 24, 2006
Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys. Neurotoxicol Teratol (2011) 2.41
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Early childhood general anaesthesia exposure and neurocognitive development. Br J Anaesth (2010) 1.67
Nitrative and oxidative stress in toxicology and disease. Toxicol Sci (2009) 1.44
Potential neurotoxicity of ketamine in the developing rat brain. Toxicol Sci (2009) 1.33
Ketamine enhances human neural stem cell proliferation and induces neuronal apoptosis via reactive oxygen species-mediated mitochondrial pathway. Anesth Analg (2013) 1.03
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Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture. Toxicol Sci (2012) 0.93
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Neuropathological sequelae of developmental exposure to antiepileptic and anesthetic drugs. Front Neurol (2012) 0.90
Chronic ketamine administration modulates midbrain dopamine system in mice. PLoS One (2012) 0.88
Simvastatin prevents dopaminergic neurodegeneration in experimental parkinsonian models: the association with anti-inflammatory responses. PLoS One (2011) 0.87
Neocortex and allocortex respond differentially to cellular stress in vitro and aging in vivo. PLoS One (2013) 0.84
Anaesthetics-induced neurotoxicity in developing brain: an update on preclinical evidence. Brain Sci (2014) 0.82
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Ketamine affects the neurogenesis of rat fetal neural stem progenitor cells via the PI3K/Akt-p27 signaling pathway. Birth Defects Res B Dev Reprod Toxicol (2014) 0.79
The neurotoxicity of nitrous oxide: the facts and "putative" mechanisms. Brain Sci (2014) 0.78
Involvement of sphingolipids in ethanol neurotoxicity in the developing brain. Brain Sci (2013) 0.78
Ketamine-Induced Apoptosis in Normal Human Urothelial Cells: A Direct, N-Methyl-d-Aspartate Receptor-Independent Pathway Characterized by Mitochondrial Stress. Am J Pathol (2016) 0.77
Neuroprotective effect of lovastatin by inhibiting NMDA receptor1 in 6-hydroxydopamine treated PC12 cells. Int J Clin Exp Med (2014) 0.77
Positron Emission Tomography with [(18)F]FLT Revealed Sevoflurane-Induced Inhibition of Neural Progenitor Cell Expansion in vivo. Front Neurol (2014) 0.76
Distinct effects of ketamine and acetyl l-carnitine on the dopamine system in zebrafish. Neurotoxicol Teratol (2016) 0.76
Modeling anesthetic developmental neurotoxicity using human stem cells. Semin Cardiothorac Vasc Anesth (2013) 0.76
Developmental neurotoxicity screening using human embryonic stem cells. Exp Neurol (2012) 0.76
Repeated ketamine administration alters N-methyl-D-aspartic acid receptor subunit gene expression: implication of genetic vulnerability for ketamine abuse and ketamine psychosis in humans. Exp Biol Med (Maywood) (2014) 0.76
Ketamine exposure during embryogenesis inhibits cellular proliferation in rat fetal cortical neurogenic regions. Acta Anaesthesiol Scand (2016) 0.75
Emerging model in anesthetic developmental neurotoxicity: human stem cells. Int J Clin Anesthesiol (2013) 0.75
Ketamine causes mitochondrial dysfunction in human induced pluripotent stem cell-derived neurons. PLoS One (2015) 0.75
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
Cross-platform comparability of microarray technology: intra-platform consistency and appropriate data analysis procedures are essential. BMC Bioinformatics (2005) 3.93
Ketamine-induced neuronal cell death in the perinatal rhesus monkey. Toxicol Sci (2007) 3.22
Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain Res (2005) 2.67
Is tranexamic acid effective and safe in spinal surgery? A meta-analysis of randomized controlled trials. Eur Spine J (2013) 2.42
Maternal smoking during pregnancy and childhood obesity. Am J Epidemiol (2002) 2.27
Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain. Brain (2011) 2.27
Childhood obesity is associated with maternal smoking in pregnancy. Eur J Pediatr (2002) 1.77
Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain. Int J Dev Neurosci (2009) 1.76
Routine complete capsular closure during hip arthroscopy. Arthrosc Tech (2013) 1.64
Anterior versus posterior approach for treatment of thoracolumbar burst fractures: a meta-analysis. Eur Spine J (2013) 1.49
Osteochondral lesions of the talus: effect of defect size and plantarflexion angle on ankle joint stresses. Am J Sports Med (2012) 1.44
Nitrative and oxidative stress in toxicology and disease. Toxicol Sci (2009) 1.44
GSTT1 null genotype contributes to coronary heart disease risk: a meta-analysis. Mol Biol Rep (2012) 1.39
Silver nanoparticle induced blood-brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells. Toxicol Sci (2010) 1.35
Potential neurotoxicity of ketamine in the developing rat brain. Toxicol Sci (2009) 1.33
Inhalation anesthetic-induced neuronal damage in the developing rhesus monkey. Neurotoxicol Teratol (2011) 1.30
Strategies and experimental models for evaluating anesthetics: effects on the developing nervous system. Anesth Analg (2008) 1.23
Ontogeny of the N-methyl-D-aspartate (NMDA) receptor system and susceptibility to neurotoxicity. Toxicol Sci (2002) 1.15
Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles. Neurotoxicology (2009) 1.14
Overview: Using mode of action and life stage information to evaluate the human relevance of animal toxicity data. Crit Rev Toxicol (2006) 1.14
Conditions of endoplasmic reticulum stress stimulate lipid droplet formation in Saccharomyces cerevisiae. Biochem J (2009) 1.14
Relationship between different skin incisions and the injury of the infrapatellar branch of the saphenous nerve during anterior cruciate ligament reconstruction. Chin Med J (Engl) (2007) 1.12
ACB-PCR quantification of K-RAS codon 12 GAT and GTT mutant fraction in colon tumor and non-tumor tissue. Cancer Invest (2010) 1.09
SOXs in human prostate cancer: implication as progression and prognosis factors. BMC Cancer (2012) 1.08
Evidence of capsular defect following hip arthroscopy. Knee Surg Sports Traumatol Arthrosc (2013) 1.06
Neurobehavioral assessment: a survey of use and value in safety assessment studies. Toxicol Sci (2003) 1.04
Mechanistic toxicity evaluation of uncoated and PEGylated single-walled carbon nanotubes in neuronal PC12 cells. ACS Nano (2011) 1.03
Effects of transforming growth factor-beta1 and vascular endothelial growth factor 165 gene transfer on Achilles tendon healing. Matrix Biol (2009) 1.02
Pubertal delay in male nonhuman primates (Macaca mulatta) treated with methylphenidate. Proc Natl Acad Sci U S A (2011) 1.02
Global analysis of the differentially expressed miRNAs of prostate cancer in Chinese patients. BMC Genomics (2013) 1.01
Adenovirus-mediated transfer of siRNA against Runx2/Cbfa1 inhibits the formation of heterotopic ossification in animal model. Biochem Biophys Res Commun (2006) 1.01
Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors. Neurotoxicology (2005) 0.99
Neuroprotective efficacy of a new brain-penetrating C-Abl inhibitor in a murine Parkinson's disease model. PLoS One (2013) 0.97
Overlapping but distinct effects of genistein and ethinyl estradiol (EE(2)) in female Sprague-Dawley rats in multigenerational reproductive and chronic toxicity studies. Reprod Toxicol (2008) 0.97
The utility of a rodent model in detecting pediatric drug-induced nephrotoxicity. Toxicol Sci (2007) 0.97
Protective effects of 7-nitroindazole on ketamine-induced neurotoxicity in rat forebrain culture. Neurotoxicology (2008) 0.96
MicroRNA-224 inhibits progression of human prostate cancer by downregulating TRIB1. Int J Cancer (2014) 0.96
MicroRNA-23b downregulates peroxiredoxin III in human prostate cancer. FEBS Lett (2012) 0.95
A novel polysaccharide from Se-enriched Ganoderma lucidum induces apoptosis of human breast cancer cells. Oncol Rep (2011) 0.95
Proteome analysis of Saccharomyces cerevisiae under metal stress by two-dimensional differential gel electrophoresis. Electrophoresis (2003) 0.95
Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. BMC Bioinformatics (2007) 0.94
A minimally invasive, translational biomarker of ketamine-induced neuronal death in rats: microPET Imaging using 18F-annexin V. Toxicol Sci (2009) 0.94
Ketamine-induced neuronal damage and altered N-methyl-D-aspartate receptor function in rat primary forebrain culture. Toxicol Sci (2012) 0.93
In silico drug repositioning: what we need to know. Drug Discov Today (2012) 0.93
[Expression and clinical significance of HMGB1 and RAGE in cervical squamous cell carcinoma]. Zhonghua Zhong Liu Za Zhi (2008) 0.92
Induction of apoptosis and G2/M arrest by 2-methoxyestradiol in human cervical cancer HeLaS3 cells. Anticancer Res (2004) 0.92
Ketamine-induced neurotoxicity and changes in gene expression in the developing rat brain. Curr Neuropharmacol (2011) 0.92
A pilot study of preemptive morphine analgesia in preterm neonates: effects on head circumference, social behavior, and response latencies in early childhood. Neurotoxicol Teratol (2011) 0.92
An electrochemical stripping metalloimmunoassay based on silver-enhanced gold nanoparticle label. Biosens Bioelectron (2005) 0.91
Effect of methylphenidate on time perception in children with attention-deficit/hyperactivity disorder. Exp Clin Psychopharmacol (2004) 0.91
Articular cartilage repair using dedifferentiated articular chondrocytes and bone morphogenetic protein 4 in a rabbit model of articular cartilage defects. Arthritis Rheum (2008) 0.91
Synergistic inhibition of endochondral bone formation by silencing Hif1α and Runx2 in trauma-induced heterotopic ossification. Mol Ther (2011) 0.90
Androgen deficiency and defective intracrine processing of dehydroepiandrosterone in salivary glands in Sjögren's syndrome. J Rheumatol (2008) 0.90
A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools. BMC Bioinformatics (2005) 0.90
Plasma levels of parent compound and metabolites after doses of either d-fenfluramine or d-3,4-methylenedioxymethamphetamine (MDMA) that produce long-term serotonergic alterations. Neurotoxicology (2003) 0.90
Developmental aspects of timing behavior in children. Neurotoxicol Teratol (2004) 0.89
Comparison of osteogenic potentials of BMP4 transduced stem cells from autologous bone marrow and fat tissue in a rabbit model of calvarial defects. Calcif Tissue Int (2009) 0.89
Developmental origins of adult diseases and neurotoxicity: epidemiological and experimental studies. Neurotoxicology (2012) 0.89
Mechanisms for 2-methoxyestradiol-induced apoptosis of prostate cancer cells. FEBS Lett (2002) 0.88
Incorporating children's toxicokinetics into a risk framework. Environ Health Perspect (2004) 0.88
Preclinical assessment of ketamine. CNS Neurosci Ther (2013) 0.88
Comparative effects of substituted amphetamines (PMA, MDMA, and METH) on monoamines in rat caudate: a microdialysis study. Ann N Y Acad Sci (2002) 0.88
Identification of novel serological tumor markers for human prostate cancer using integrative transcriptome and proteome analysis. Med Oncol (2012) 0.88
Effects of co-culturing BMSCs and auricular chondrocytes on the elastic modulus and hypertrophy of tissue engineered cartilage. Biomaterials (2012) 0.88
Anesthetic-induced oxidative stress and potential protection. ScientificWorldJournal (2010) 0.88
Fibrin sealant before wound closure in total knee arthroplasty reduced blood loss: a meta-analysis. Knee Surg Sports Traumatol Arthrosc (2014) 0.88
BMP4 increases canonical transient receptor potential protein expression by activating p38 MAPK and ERK1/2 signaling pathways in pulmonary arterial smooth muscle cells. Am J Respir Cell Mol Biol (2013) 0.87