Published in Clin Sci Mol Med on April 01, 1975
Investigation of tissue organelles by a combination of analytical subcellular fractionation and enzymic microanalysis: a new approach to pathology. J Clin Pathol (1981) 1.39
Mitochondrial enzyme activities in liver biopsies from patients with alcoholic liver disease. Gut (1978) 1.27
In vitro determination of small intestinal permeability: demonstration of a persistent defect in patients with coeliac disease. Gut (1984) 1.20
Enzymic analysis of endomyocardial biopsy specimens from patients with cardiomyopathies. Br Heart J (1977) 1.06
Lysophosphatidylcholine increases rat ileal permeability to macromolecules. Gut (1985) 0.99
Coeliac syndrome: biochemical mechanisms and the missing peptidase hypothesis revisted. Gut (1984) 0.97
Hyperenteroglucagonaemia and small intestinal mucosal growth after colonic perfusion of glucose in rats. Gut (1985) 0.96
DNA synthesis by jejunal mucosa in responsive and non-responsive coeliac disease. Br Med J (1977) 0.96
Analytical subcellular fractionation of needle-biopsy specimens from human liver. Biochem J (1978) 0.93
Intestinal lactase, sucrase, and alkaline phosphatase in 373 patients with coeliac disease. J Clin Pathol (1984) 0.89
Morphological and biochemical findings in jejunal biopsies from patients with multiple sclerosis. J Neurol Neurosurg Psychiatry (1979) 0.89
Subcellular localisation of vitamin B12 during absorption in the guinea-pig ileum. Gut (1981) 0.88
Phospholipase A2 inhibition prevents mucosal damage associated with small intestinal ischaemia in rats. Gut (1988) 0.83
Ileal mucosal bile acid absorption is increased in Cftr knockout mice. BMC Gastroenterol (2001) 0.82
Gastrointestinal regulatory peptide storage granule abnormalities in jejunal mucosal diseases. Gut (1984) 0.82
Biochemical studies of the isolated rat glomerulus and the effects of puromycin aminonucleoside administration. Br J Exp Pathol (1980) 0.82
Characteristics and postnatal development of the acid lipase activity of the rat small intestine. Biochem J (1977) 0.79
Jejunal mucosal enzyme activities, regulatory peptides and organelle pathology of the enteropathy of common variable immunodeficiency. Gut (1986) 0.78
Organelle pathology in ulcerative and Crohn's colitis with special reference to the lysosomal alterations. Gut (1984) 0.78
Lysosomes and the connective tissue diseases. J Clin Pathol Suppl (R Coll Pathol) (1978) 0.75
Clinical science and the small intestine. Gut (1989) 0.75
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell (2000) 5.31
Evidence based purchasing: understanding results of clinical trials and systematic reviews. BMJ (1995) 4.75
The patient-centredness of consultations and outcome in primary care. Br J Gen Pract (1999) 4.67
Diet or diet plus physical activity versus usual care in patients with newly diagnosed type 2 diabetes: the Early ACTID randomised controlled trial. Lancet (2011) 4.35
Population requirement for primary hip-replacement surgery: a cross-sectional study. Lancet (1999) 4.29
Clinical features of colorectal cancer before diagnosis: a population-based case-control study. Br J Cancer (2005) 4.19
A randomized controlled trial of antibiotics on symptom resolution in patients presenting to their general practitioner with a sore throat. Br J Gen Pract (1997) 4.18
What constitutes controlled hypertension? Patient based comparison of hypertension guidelines. BMJ (1996) 4.11
The impact of patients' preferences on the treatment of atrial fibrillation: observational study of patient based decision analysis. BMJ (2000) 3.93
A randomized controlled trial and economic evaluation of counselling in primary care. Br J Gen Pract (1998) 3.84
Lysosomes of the arterial wall. I. Isolation and subcellular fractionation of cells from normal rabbit aorta. J Exp Med (1972) 3.73
What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study. Thorax (2005) 3.66
Hospital at home or acute hospital care? A cost minimisation analysis. BMJ (1998) 3.33
Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives. Health Technol Assess (2001) 3.32
Childhood obesity and adult cardiovascular mortality: a 57-y follow-up study based on the Boyd Orr cohort. Am J Clin Nutr (1998) 3.21
Randomised controlled trial comparing effectiveness and acceptability of an early discharge, hospital at home scheme with acute hospital care. BMJ (1998) 3.15
Childhood leg length and adult mortality: follow up of the Carnegie (Boyd Orr) Survey of Diet and Health in Pre-war Britain. J Epidemiol Community Health (1998) 2.95
A general practice-based study examining the absolute risk of cardiovascular disease in treated hypertensive patients. Br J Gen Pract (1996) 2.94
Oral submucous fibrosis: review on aetiology and pathogenesis. Oral Oncol (2005) 2.94
An iron-regulated ferric reductase associated with the absorption of dietary iron. Science (2001) 2.90
Intestinal permeability and inflammation in rheumatoid arthritis: effects of non-steroidal anti-inflammatory drugs. Lancet (1984) 2.83
Relation between parasuicide, suicide, psychiatric admissions, and socioeconomic deprivation. BMJ (1995) 2.83
Parents' beliefs about vaccination: the continuing propagation of false contraindications. BMJ (1989) 2.71
A persistent defect in intestinal permeability in coeliac disease demonstrated by a 51Cr-labelled EDTA absorption test. Lancet (1983) 2.62
Childhood energy intake and adult mortality from cancer: the Boyd Orr Cohort Study. BMJ (1998) 2.60
The Bristol shared care glaucoma study: outcome at follow up at 2 years. Br J Ophthalmol (2000) 2.38
Case definition in childhood accident studies: a vital factor in determining results. Int J Epidemiol (1986) 2.32
The leaky gut of alcoholism: possible route of entry for toxic compounds. Lancet (1984) 2.30
Absorption of 51chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease. Gastroenterology (1983) 2.23
The Bristol Shared Care Glaucoma Study--validity of measurements and patient satisfaction. J Public Health Med (1997) 2.21
Localisation of enzymic defect in propionicacidaemia. Lancet (1970) 2.19
Treatment of acute paracetamol poisoning. Lancet (1968) 2.18
Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine. Gut (1986) 2.10
Caring for elderly dependents: effects on the carers' quality of life. Age Ageing (1992) 2.09
King's model for allocating service increment for teaching and research (SIFTR). BMJ (1992) 2.08
The importance of anaemia in diagnosing colorectal cancer: a case-control study using electronic primary care records. Br J Cancer (2008) 2.04
The mortality of colorectal cancer in relation to the initial symptom at presentation to primary care and to the duration of symptoms: a cohort study using medical records. Br J Cancer (2006) 2.01
The ICS-'BPH' Study: the psychometric validity and reliability of the ICSmale questionnaire. Br J Urol (1996) 1.89
The history of Crohn's disease. J R Coll Physicians Lond (1989) 1.87
Will genetic testing for predisposition for disease result in fatalism? A qualitative study of parents responses to neonatal screening for familial hypercholesterolaemia. Soc Sci Med (1999) 1.83
Breath hydrogen as a diagnostic method for hypolactasia. Lancet (1975) 1.82
The subcellular localization of di- and tri-peptide hydrolase activity in guinea-pig small intestine. Biochem J (1970) 1.81
Lactulose, 51Cr-labelled ethylenediaminetetra-acetate, L-rhamnose and polyethyleneglycol 400 [corrected] as probe markers for assessment in vivo of human intestinal permeability. Clin Sci (Lond) (1986) 1.78
Analytical subcellular fractionation of human granulocytes with reference to the localization of vitamin B12-binding proteins. Clin Sci Mol Med (1975) 1.75
Appropriateness of hospital utilization. The validity and reliability of the Intensity-Severity-Discharge Review System in a United Kingdom acute hospital setting. Med Care (1995) 1.74
Randomised trial of effectiveness of second eye cataract surgery. Lancet (1998) 1.73
The Bristol Shared Care Glaucoma Study: reliability of community optometric and hospital eye service test measures. Br J Ophthalmol (1999) 1.70
Comparison of serum procollagen III peptide concentrations and PGA index for assessment of hepatic fibrosis. Lancet (1993) 1.69
Social class and preventive health behaviour: a British example. J Epidemiol Community Health (1995) 1.69
Nanocrystal superlattices. Annu Rev Phys Chem (1998) 1.68
Development of a questionnaire for measurement of vision-related quality of life. Ophthalmic Epidemiol (1998) 1.65
Analytical subcellular fractionation of jejunal biopsy specimens: methodology and characterization of the organelles in normal tissue. Clin Sci Mol Med (1976) 1.65
How great a burden does early discharge to hospital-at-home impose on carers? A randomized controlled trial. Age Ageing (2000) 1.64
GPs' experiences of primary care mental health research: a qualitative study of the barriers to recruitment. Fam Pract (2007) 1.64
Pancreatic enzyme supplement dosage in cystic fibrosis. Lancet (1991) 1.64
Epidemiology and patterns of hospital use after parasuicide in the south west of England. J Epidemiol Community Health (1996) 1.62
Perioperative low-molecular-weight heparin. Is it effective and safe. J Bone Joint Surg Br (1995) 1.60
Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes. Diabetologia (2011) 1.59
Retracted Experimental non-steroidal anti-inflammatory drug-induced enteropathy in the rat: similarities to inflammatory bowel disease and effect of thromboxane synthetase inhibitors. Gut (1990) 1.57
A dependency syndrome related to areca nut use: some medical and psychological aspects among areca nut users in the Gujarat community in the UK. Addict Biol (2000) 1.55
Impaired prostate tumorigenesis in Egr1-deficient mice. Nat Med (2001) 1.55
Observations on the distribution of the proteinpolysaccharide complex and collagen in bovine articular cartilage. J Cell Sci (1967) 1.54
A randomised controlled trial of flexibility in routine antenatal care. BJOG (2000) 1.52
Comparison of the use of a foot pump with the use of low-molecular-weight heparin for the prevention of deep-vein thrombosis after total hip replacement. A prospective, randomized trial. J Bone Joint Surg Am (1998) 1.51
Do patients who self-harm consult their general practitioner soon after hospital discharge? A cohort study. Soc Psychiatry Psychiatr Epidemiol (2002) 1.50
In vitro activity of ciprofloxacin, sparfloxacin, ofloxacin, amikacin and rifampicin against Ghanaian isolates of Mycobacterium ulcerans. J Antimicrob Chemother (2000) 1.50
Alpha-tocopherol levels in brain are not altered in Parkinson's disease. Ann Neurol (1992) 1.49
Analytical subcellular fractionation of human granulocytes with special reference to the localization of enzymes involved in microbicidal mechanisms. Clin Sci Mol Med (1977) 1.49
Paracetamol and ibuprofen for the treatment of fever in children: the PITCH randomised controlled trial. Health Technol Assess (2009) 1.49
Estimation of cardiovascular risk in hypertensive patients in primary care. Br J Gen Pract (2000) 1.48
Mildly dyskaryotic smear results: does it matter what women know? Fam Pract (1998) 1.47
Impaired sleep in alcohol misusers and dependent alcoholics and the impact upon outcome. Alcohol Clin Exp Res (1999) 1.46
Communication between the dentist and the dental technician. Br Dent J (2000) 1.46
Familial HBsAg-positive hepatoma: treatment with orthotopic liver transplantation and specific immunoglobulin. Br Med J (1978) 1.46
Mycobacterium ulcerans disease; Buruli ulcer. Trans R Soc Trop Med Hyg (2000) 1.44
An outreach education and treatment project in Ghana for the early stage of Mycobacterium ulcerans disease. Trans R Soc Trop Med Hyg (2003) 1.44
Cohort study in South and West England of the influence of specialization on the management and outcome of patients with oesophageal and gastric cancers. Br J Surg (2002) 1.43
Trials in primary care: statistical issues in the design, conduct and evaluation of complex interventions. Stat Methods Med Res (2010) 1.42
Organic chemistry of C60 (Buckminsterfullerene): chromatography and osmylation. J Org Chem (1990) 1.42
The absorption of glycine and glycine oligopeptides by the rat. Clin Sci (1970) 1.42
Patient-Reported Outcomes after Monitoring, Surgery, or Radiotherapy for Prostate Cancer. N Engl J Med (2016) 1.41
Surveying. Br Dent J (2000) 1.41
Raised hepatic free fatty acids in a patient with acute fatty liver after gastric surgery for morbid obesity. J Clin Pathol (1986) 1.41
Small intestine permeability in schizophrenia. Br J Psychiatry (1989) 1.41
Quality of life measures and outcome in alcohol-dependent men and women. Alcohol (2000) 1.41
Self reported health of people in an area contaminated by chromium waste: interview study. BMJ (2000) 1.41
Studies on chemical composition of menisci from the human knee-joint. Proc R Soc Med (1971) 1.39
In vivo studies on the relationship between intestinal iron (Fe3+) absorption, hypoxia and erythropoiesis in the mouse. Br J Haematol (1988) 1.39
Scoring the short form ICSmaleSF questionnaire. International Continence Society. J Urol (2000) 1.39
Investigation of tissue organelles by a combination of analytical subcellular fractionation and enzymic microanalysis: a new approach to pathology. J Clin Pathol (1981) 1.39
The risk of pancreatic cancer in symptomatic patients in primary care: a large case-control study using electronic records. Br J Cancer (2012) 1.38
Urine and faecal porphyrin profiles by reversed-phase high-performance liquid chromatography in the porphyrias. Clin Chim Acta (1984) 1.38
Increased expression of c-myc proto-oncogene in biopsies of ulcerative colitis and Crohn's colitis. Gut (1992) 1.38
An assessment of academic performance and personality. Med Educ (1991) 1.38
An alarming lack of public awareness towards oral cancer. Br Dent J (1999) 1.37
Randomised controlled trial of community based speech and language therapy in preschool children. BMJ (2000) 1.36
Plus ça change: predictors of birthweight in two national studies. Br J Obstet Gynaecol (1983) 1.33
Effects of oral versus intravenous nutrition on intestinal adaptation after small bowel resection in the dog. Gastroenterology (1976) 1.31
Intestinal permeability to 51Cr-EDTA in rats with experimentally induced enteropathy. Gut (1985) 1.31