Published in Mol Cancer Ther on February 01, 2006
Inactivation of host Akt/protein kinase B signaling by bacterial pore-forming toxins. Mol Biol Cell (2008) 1.26
Targeting Akt3 signaling in malignant melanoma using isoselenocyanates. Clin Cancer Res (2009) 1.22
Diet and prostate cancer: mechanisms of action and implications for chemoprevention. Nat Rev Urol (2010) 1.14
Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer. Cancer Biol Ther (2009) 0.97
Telomerase as an important target of androgen signaling blockade for prostate cancer treatment. Mol Cancer Ther (2010) 0.93
Effects of selenite and genistein on G2/M cell cycle arrest and apoptosis in human prostate cancer cells. Nutr Cancer (2009) 0.92
Sodium selenite increases the activity of the tumor suppressor protein, PTEN, in DU-145 prostate cancer cells. Nutr Cancer (2009) 0.91
Activation of FOXO1 is critical for the anticancer effect of methylseleninic acid in prostate cancer cells. Prostate (2010) 0.86
Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)--against colon cancer. Bioorg Med Chem Lett (2009) 0.86
Sodium selenite inhibits interleukin-6-mediated androgen receptor activation in prostate cancer cells via upregulation of c-Jun. Clin Chim Acta (2007) 0.85
The neurodegenerative effects of selenium are inhibited by FOXO and PINK1/PTEN regulation of insulin/insulin-like growth factor signaling in Caenorhabditis elegans. Neurotoxicology (2014) 0.82
Epigenetic regulation of inflammatory gene expression in macrophages by selenium. J Nutr Biochem (2014) 0.82
1,4-phenylenebis(methylene)selenocyanate, but not selenomethionine, inhibits androgen receptor and Akt signaling in human prostate cancer cells. Cancer Prev Res (Phila) (2010) 0.82
PINK1 enhances insulin-like growth factor-1-dependent Akt signaling and protection against apoptosis. Neurobiol Dis (2011) 0.82
Chronic over-nutrition and dysregulation of GSK3 in diseases. Nutr Metab (Lond) (2016) 0.77
Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition. Pharmacol Res (2015) 0.77
Pleural plaques and their effect on lung function in Libby vermiculite miners. Chest (2014) 3.21
Tumor flare reaction associated with lenalidomide treatment in patients with chronic lymphocytic leukemia predicts clinical response. Cancer (2010) 1.90
Human prx1 gene is a target of Nrf2 and is up-regulated by hypoxia/reoxygenation: implication to tumor biology. Cancer Res (2007) 1.80
Central role of IL-6 receptor signal-transducing chain gp130 in activation of L-selectin adhesion by fever-range thermal stress. Immunity (2004) 1.76
Validated protocol for FoxP3 reveals increased expression in type 1 diabetes patients. Cytometry B Clin Cytom (2009) 1.71
NADPH oxidase limits innate immune responses in the lungs in mice. PLoS One (2010) 1.69
Impact of nasal continuous positive airway pressure therapy on markers of platelet activation in patients with obstructive sleep apnea. Respiration (2008) 1.51
The transcriptomics of de novo androgen biosynthesis in prostate cancer cells following androgen reduction. Cancer Biol Ther (2010) 1.46
Endotoxin induces rapid metalloproteinase-mediated shedding followed by up-regulation of the monocyte hemoglobin scavenger receptor CD163. J Leukoc Biol (2002) 1.44
Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. Cancer Res (2003) 1.44
Human peroxiredoxin 1 and 2 are not duplicate proteins: the unique presence of CYS83 in Prx1 underscores the structural and functional differences between Prx1 and Prx2. J Biol Chem (2007) 1.41
Prx1 suppresses radiation-induced c-Jun NH2-terminal kinase signaling in lung cancer cells through interaction with the glutathione S-transferase Pi/c-Jun NH2-terminal kinase complex. Cancer Res (2006) 1.38
Prostate specific antigen expression is down-regulated by selenium through disruption of androgen receptor signaling. Cancer Res (2004) 1.33
Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Mol Cancer Ther (2007) 1.30
Androgen receptor signaling intensity is a key factor in determining the sensitivity of prostate cancer cells to selenium inhibition of growth and cancer-specific biomarkers. Mol Cancer Ther (2005) 1.26
Biological effects and clinical significance of lenalidomide-induced tumour flare reaction in patients with chronic lymphocytic leukaemia: in vivo evidence of immune activation and antitumour response. Br J Haematol (2011) 1.26
Peroxiredoxin 1 interacts with androgen receptor and enhances its transactivation. Cancer Res (2007) 1.15
AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia. Cell Signal (2011) 1.14
Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer. Cancer Res (2009) 1.13
Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress. Cell Signal (2010) 1.13
Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules. J Immunol (2004) 1.12
Air pollution and lung cancer in Europe. Lancet Oncol (2013) 1.10
Ganciclovir inhibits lymphocyte proliferation by impairing DNA synthesis. Biol Blood Marrow Transplant (2007) 1.10
Hypoxia increases androgen receptor activity in prostate cancer cells. Cancer Res (2006) 1.09
Impaired alveolar macrophage response to Haemophilus antigens in chronic obstructive lung disease. Am J Respir Crit Care Med (2006) 1.08
Monomethylated selenium inhibits growth of LNCaP human prostate cancer xenograft accompanied by a decrease in the expression of androgen receptor and prostate-specific antigen (PSA). Prostate (2006) 1.07
Use of cell-tracking dyes to determine proliferation precursor frequencies of antigen-specific T cells. Methods Mol Biol (2004) 1.05
Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells. Clin Cancer Res (2005) 1.05
Comment on "HRCT/CT and Associated Spirometric Effects of Low Libby Amphibole Asbestos Exposure" by Lockey et al (2015). J Occup Environ Med (2015) 1.05
Arsenic trioxide affects signal transducer and activator of transcription proteins through alteration of protein tyrosine kinase phosphorylation. Clin Cancer Res (2006) 1.05
Endoplasmic reticulum stress signal mediators are targets of selenium action. Cancer Res (2005) 1.05
A randomized trial of ex vivo CD40L activation of a dendritic cell vaccine in colorectal cancer patients: tumor-specific immune responses are associated with improved survival. Clin Cancer Res (2010) 1.05
Microarray Data Mining for Potential Selenium Targets in Chemoprevention of Prostate Cancer. Cancer Genomics Proteomics (2005) 0.99
Prx1 enhances androgen receptor function in prostate cancer cells by increasing receptor affinity to dihydrotestosterone. Mol Cancer Res (2009) 0.99
The t10,c12 isomer of conjugated linoleic acid stimulates mammary tumorigenesis in transgenic mice over-expressing erbB2 in the mammary epithelium. Carcinogenesis (2007) 0.98
Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival. Anticancer Res (2010) 0.98
Methyl selenium metabolites decrease prostate-specific antigen expression by inducing protein degradation and suppressing androgen-stimulated transcription. Mol Cancer Ther (2004) 0.98
Prevention of mammary cancer with conjugated linoleic acid: role of the stroma and the epithelium. J Mammary Gland Biol Neoplasia (2003) 0.97
Chemotherapeutic sensitization by endoplasmic reticulum stress: increasing the efficacy of taxane against prostate cancer. Cancer Biol Ther (2009) 0.97
Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response. J Lipid Res (2008) 0.97
Synergy between selenium and vitamin E in apoptosis induction is associated with activation of distinctive initiator caspases in human prostate cancer cells. Cancer Res (2003) 0.96
20(S)-protopanaxadiol-aglycone downregulation of the full-length and splice variants of androgen receptor. Int J Cancer (2012) 0.95
Characterization of regulatory T cells in urban newborns. Clin Mol Allergy (2009) 0.95
Selenium disrupts estrogen receptor (alpha) signaling and potentiates tamoxifen antagonism in endometrial cancer cells and tamoxifen-resistant breast cancer cells. Mol Cancer Ther (2005) 0.95
A novel human cancer vaccine elicits cellular responses to the tumor-associated antigen, human chorionic gonadotropin beta. Clin Cancer Res (2004) 0.95
Identification of molecular targets associated with selenium-induced growth inhibition in human breast cells using cDNA microarrays. Cancer Res (2002) 0.94
Telomerase as an important target of androgen signaling blockade for prostate cancer treatment. Mol Cancer Ther (2010) 0.93
Dietary intake of conjugated linoleic acids and risk of premenopausal and postmenopausal breast cancer, Western New York Exposures and Breast Cancer Study (WEB Study). Cancer Epidemiol Biomarkers Prev (2004) 0.92
Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells. Mol Cancer Ther (2005) 0.91
Association between CD4(+)CD25(high) T cells and atopy in children. J Allergy Clin Immunol (2007) 0.91
Isomers of conjugated linoleic acid differ in their effects on angiogenesis and survival of mouse mammary adipose vasculature. J Nutr (2004) 0.91
Role of cervical dendritic cell subsets, co-stimulatory molecules, cytokine secretion profile and beta-estradiol in development of sequalae to Chlamydia trachomatis infection. Reprod Biol Endocrinol (2008) 0.91
Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. Biochem Biophys Res Commun (2007) 0.90
Pretreatment levels of circulating Th1 and Th2 cytokines, and their ratios, are associated with ER-negative and triple negative breast cancers. Breast Cancer Res Treat (2013) 0.90
Human ovarian tumor ascites fluids rapidly and reversibly inhibit T cell receptor-induced NF-κB and NFAT signaling in tumor-associated T cells. Cancer Immun (2013) 0.89
Cervical cytokine responses in women with primary or recurrent chlamydial infection. J Interferon Cytokine Res (2007) 0.88
NFkappaB1/p50 is not required for tumor necrosis factor-stimulated growth of primary mammary epithelial cells: implications for NFkappaB2/p52 and RelB. Endocrinology (2006) 0.88
Regulation and localization of endogenous human tristetraprolin. Arthritis Res Ther (2003) 0.88
Methyl selenocysteine: single-dose pharmacokinetics in men. Cancer Prev Res (Phila) (2011) 0.88
Tracking immune cell proliferation and cytotoxic potential using flow cytometry. Methods Mol Biol (2011) 0.88
Multiparameter precursor analysis of T-cell responses to antigen. J Immunol Methods (2003) 0.87
Cell cycle arrest biomarkers in human lung cancer cells after treatment with selenium in culture. Cancer Epidemiol Biomarkers Prev (2003) 0.87
Selenium disrupts estrogen signaling by altering estrogen receptor expression and ligand binding in human breast cancer cells. Cancer Res (2005) 0.87
Systematic review of pleural plaques and lung function. Inhal Toxicol (2014) 0.86
Toll-like receptor activation enhances cell-mediated immunity induced by an antibody vaccine targeting human dendritic cells. J Transl Med (2007) 0.86
Detection of conjugated C16 PUFAs in rat tissues as possible partial beta-oxidation products of naturally occurring conjugated linoleic acid and its metabolites. Biochim Biophys Acta (2004) 0.86
Predictors of immunosuppressive regulatory T lymphocytes in healthy women. J Cancer Epidemiol (2012) 0.86
Inhibition of angiogenesis by the cancer chemopreventive agent conjugated linoleic acid. Cancer Res (2002) 0.86
Activation of FOXO1 is critical for the anticancer effect of methylseleninic acid in prostate cancer cells. Prostate (2010) 0.86
Rheumatoid peripheral blood phagocytes are primed for activation but have impaired Fc-mediated generation of reactive oxygen species. Arthritis Res Ther (2007) 0.85
The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific. Prostate (2013) 0.84
Image cytometry-based detection of aneuploidy by fluorescence in situ hybridization in suspension. Cytometry A (2012) 0.84
Doxorubicin and selenium cooperatively induce fas signaling in the absence of Fas/Fas ligand interaction. Anticancer Res (2007) 0.84
Treating octogenarian and nonagenarian acute myeloid leukemia patients--predictive prognostic models. Cancer (2009) 0.83
Enhanced red and near infrared detection in flow cytometry using avalanche photodiodes. Cytometry A (2008) 0.83
Attenuation of estrogen receptor alpha (ERalpha) signaling by selenium in breast cancer cells via downregulation of ERalpha gene expression. Breast Cancer Res Treat (2005) 0.83
Augmented suppression of androgen receptor signaling by a combination of alpha-tocopheryl succinate and methylseleninic acid. Cancer (2006) 0.83
Novel lipophilic tracking dyes for monitoring cell proliferation. Immunol Invest (2007) 0.83
Prostate cancer cells differ in testosterone accumulation, dihydrotestosterone conversion, and androgen receptor signaling response to steroid 5α-reductase inhibitors. Prostate (2013) 0.82
Antigen presentation by human uterine epithelial cells to autologous T cells. Am J Reprod Immunol (2006) 0.82
Flow cytometry as a diagnostic tool in lymphomatous or leukemic meningitis: ready for prime time? Cancer (2011) 0.82
A method for measuring intracellular free magnesium concentration in platelets using flow cytometry. Magnes Res (2007) 0.82
cis-9, trans-11 CLA derived endogenously from trans-11 18:1 reduces cancer risk in rats. J Nutr (2003) 0.82
Metachronous and synchronous presentation of acute myeloid leukemia and lung cancer. Leuk Res (2009) 0.82
High superoxide dismutase and low glutathione peroxidase activities in red blood cells predict susceptibility of lung cancer patients to radiation pneumonitis. Free Radic Biol Med (2006) 0.82
Optimized staining and proliferation modeling methods for cell division monitoring using cell tracking dyes. J Vis Exp (2012) 0.81
Cellular and molecular effects of alpha-tocopheryloxybutyrate: lessons for the design of vitamin E analog for cancer prevention. Anticancer Res (2005) 0.81
CD19 expression in acute leukemia is not restricted to the cytogenetically aberrant populations. Leuk Lymphoma (2013) 0.81
The anticarcinogenic effect of trans-11 18:1 is dependent on its conversion to cis-9, trans-11 CLA by delta9-desaturase in rats. J Nutr (2004) 0.81
The antiandrogenic effect of finasteride against a mutant androgen receptor. Cancer Biol Ther (2011) 0.80
Evidence of a field effect associated with mammary cancer chemoprevention by methylseleninic acid. Anticancer Res (2002) 0.80
Monoallelic and biallelic deletions of 13q14.3 in chronic lymphocytic leukemia: FISH vs miRNA RT-qPCR detection. Am J Clin Pathol (2012) 0.80
Analysis of protein redox modification by hypoxia. Prep Biochem Biotechnol (2006) 0.80
Yield of Terminal Duct Lobule Units in Normal Breast Stereotactic Core Biopsy Specimens: Implications for Biomarker Studies. Breast J (2000) 0.79
Advantages of hydrophobic culture bags over flasks for the generation of monocyte-derived dendritic cells for clinical applications. J Immunol Methods (2002) 0.79
Weight-of-evidence evaluation of long-term ozone exposure and cardiovascular effects. Crit Rev Toxicol (2014) 0.79
Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes. PeerJ (2013) 0.79
Fluorescent human lung macrophages analyzed by spectral confocal laser scanning microscopy and multispectral cytometry. Microsc Res Tech (2005) 0.79
Cytoreduction with gemtuzumab ozogamicin and cytarabine prior to allogeneic stem cell transplant for relapsed/refractory acute myeloid leukemia. Leuk Lymphoma (2011) 0.79