Published in Diabetes on March 01, 2006
A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion. J Clin Invest (2011) 2.25
Cellular plasticity within the pancreas--lessons learned from development. Dev Cell (2010) 1.58
Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation. Dev Biol (2008) 1.55
Biphasic Ngn3 expression in the developing pancreas. Dev Dyn (2008) 1.47
Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors. Mol Cell Biol (2008) 1.46
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development (2012) 1.39
Historical perspective: beginnings of the beta-cell: current perspectives in beta-cell development. Diabetes (2011) 1.30
Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol (2011) 1.27
Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha. Diabetes (2009) 1.19
Development of a conditionally immortalized human pancreatic β cell line. J Clin Invest (2014) 1.17
Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium. Dev Biol (2011) 1.11
Vascular instruction of pancreas development. Development (2012) 1.01
Deconstructing pancreas developmental biology. Cold Spring Harb Perspect Biol (2012) 0.98
Alternative oxidase expression in the mouse enables bypassing cytochrome c oxidase blockade and limits mitochondrial ROS overproduction. PLoS Genet (2013) 0.91
Mouse muscle as an ectopic permissive site for human pancreatic development. Diabetes (2013) 0.89
Sox9: a master regulator of the pancreatic program. Rev Diabet Stud (2014) 0.84
The hexosamine biosynthesis pathway is essential for pancreatic beta cell development. J Biol Chem (2009) 0.84
Crosstalk between the developing pancreas and its blood vessels: an evolving dialog. Semin Cell Dev Biol (2012) 0.84
New insights into endocrine pancreatic development: the role of environmental factors. Horm Res Paediatr (2010) 0.83
HIF1α and pancreatic β-cell development. FASEB J (2012) 0.82
Activation of the transcription factor carbohydrate-responsive element-binding protein by glucose leads to increased pancreatic beta cell differentiation in rats. Diabetologia (2012) 0.81
Differential expression pattern of ZAC in developing mouse and human pancreas. J Mol Histol (2011) 0.78
Inhibition of gamma-secretase activity promotes differentiation of embryonic pancreatic precursor cells into functional islet-like clusters in poly(ethylene glycol) hydrogel culture. Tissue Eng Part A (2010) 0.76
Influence of in vitro and in vivo oxygen modulation on β cell differentiation from human embryonic stem cells. Stem Cells Transl Med (2013) 0.75
Expression and localization of Wolfram syndrome 1 gene in the developing rat pancreas. World J Gastroenterol (2009) 0.75
In Vitro Differentiation of Human Umbilical Cord Blood CD133(+)Cells into Insulin Producing Cells in Co-Culture with Rat Pancreatic Mesenchymal Stem Cells. Cell J (2015) 0.75
Three-dimensional pancreas organogenesis models. Diabetes Obes Metab (2016) 0.75
Derivation of insulin-producing beta-cells from human pluripotent stem cells. Rev Diabet Stud (2014) 0.75
Dynamic expression and localization of c-MET isoforms in the developing rat pancreas. Int J Clin Exp Pathol (2014) 0.75
Notch Signaling in Pancreatic Development. Int J Mol Sci (2015) 0.75
Small-molecule inhibitors of the cystic fibrosis transmembrane conductance regulator increase pancreatic endocrine cell development in rat and mouse. Diabetologia (2012) 0.75
Noninvasive in vivo imaging of embryonic β-cell development in the anterior chamber of the eye. Islets (2016) 0.75
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell (2008) 8.57
Activating mutations in the ABCC8 gene in neonatal diabetes mellitus. N Engl J Med (2006) 4.88
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells. Cell (2009) 4.47
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes (2009) 2.92
A third vesicular glutamate transporter expressed by cholinergic and serotoninergic neurons. J Neurosci (2002) 2.71
In vitro proliferation of cells derived from adult human beta-cells revealed by cell-lineage tracing. Diabetes (2008) 2.64
Intravenous scAAV9 delivery of a codon-optimized SMN1 sequence rescues SMA mice. Hum Mol Genet (2010) 2.26
A genetically engineered human pancreatic β cell line exhibiting glucose-inducible insulin secretion. J Clin Invest (2011) 2.25
Human β cell transcriptome analysis uncovers lncRNAs that are tissue-specific, dynamically regulated, and abnormally expressed in type 2 diabetes. Cell Metab (2012) 2.22
MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J Biol Chem (2007) 2.15
Molecular diagnosis of neonatal diabetes mellitus using next-generation sequencing of the whole exome. PLoS One (2010) 1.99
ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target. Cancer Cell Int (2010) 1.54
Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes. Dev Cell (2013) 1.46
Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development. Development (2010) 1.43
Role for FGFR2IIIb-mediated signals in controlling pancreatic endocrine progenitor cell proliferation. Proc Natl Acad Sci U S A (2002) 1.36
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. J Neurosci (2008) 1.34
Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells. PLoS One (2009) 1.32
Control of beta-cell differentiation by the pancreatic mesenchyme. Diabetes (2007) 1.30
The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells. PLoS Genet (2013) 1.28
Expression of vesicular glutamate transporters in rat lumbar spinal cord, with a note on dorsal root ganglia. J Comp Neurol (2004) 1.25
Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro. PLoS One (2011) 1.23
New ABCC8 mutations in relapsing neonatal diabetes and clinical features. Diabetes (2007) 1.22
Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha. Diabetes (2009) 1.19
Development of a conditionally immortalized human pancreatic β cell line. J Clin Invest (2014) 1.17
Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas. Dev Dyn (2005) 1.14
Label-retaining cells in the rat pancreas: location and differentiation potential in vitro. Diabetes (2003) 1.11
Quantitative comparison of constitutive promoters in human ES cells. PLoS One (2010) 1.08
Beta cells within single human islets originate from multiple progenitors. PLoS One (2008) 1.05
Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9. Diabetes (2011) 1.04
Developmentally regulated expression of VGLUT3 during early post-natal life. Neuropharmacology (2005) 1.01
Large CTG repeats trigger p16-dependent premature senescence in myotonic dystrophy type 1 muscle precursor cells. Am J Pathol (2009) 0.99
Neonatal hyperglycaemia and abnormal development of the pancreas. Best Pract Res Clin Endocrinol Metab (2008) 0.98
Concise review: in search of unlimited sources of functional human pancreatic beta cells. Stem Cells Transl Med (2012) 0.97
Plasticity of adult human pancreatic duct cells by neurogenin3-mediated reprogramming. PLoS One (2012) 0.97
Class 3 semaphorins influence oligodendrocyte precursor recruitment and remyelination in adult central nervous system. Brain (2011) 0.95
Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing β-like cells. Diabetes (2013) 0.95
Specific maternal microchimeric T cells targeting fetal antigens in β cells predispose to auto-immune diabetes in the child. J Autoimmun (2011) 0.94
Opposing effects of mutant ras oncoprotein on human fibroblast and epithelial cell proliferation: implications for models of human tumorigenesis. Oncogene (2004) 0.92
Metabolic acidosis induced by Plasmodium falciparum intraerythrocytic stages alters blood-brain barrier integrity. J Cereb Blood Flow Metab (2010) 0.91
TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol (2010) 0.90
Mesenchymal bone morphogenetic protein signaling is required for normal pancreas development. Diabetes (2010) 0.90
EGF-induced proliferation of adult human pancreatic duct cells is mediated by the MEK/ERK cascade. Lab Invest (2005) 0.89
Mouse muscle as an ectopic permissive site for human pancreatic development. Diabetes (2013) 0.89
A new strategy to generate functional insulin-producing cell lines by somatic gene transfer into pancreatic progenitors. PLoS One (2009) 0.88
Zinc finger protein 191 (ZNF191/Zfp191) is necessary to maintain neural cells as cycling progenitors. Stem Cells (2009) 0.88
Gene delivery to pancreatic exocrine cells in vivo and in vitro. BMC Biotechnol (2012) 0.87
Lysosomal amino acid transporter LYAAT-1 in the rat central nervous system: an in situ hybridization and immunohistochemical study. J Comp Neurol (2003) 0.86
Human pancreas endocrine cell populations and activating ABCC8 mutations. Horm Res Paediatr (2014) 0.84
ZENON, a novel POZ Kruppel-like DNA binding protein associated with differentiation and/or survival of late postmitotic neurons. Mol Cell Biol (2005) 0.84
Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fate. PLoS One (2011) 0.83
Early netrin-1 expression impairs central nervous system remyelination. Ann Neurol (2014) 0.83
Highly restricted diversity of TCR delta chains of the amphibian Mexican axolotl (Ambystoma mexicanum) in peripheral tissues. Eur J Immunol (2007) 0.83
Differential expression and regulation of the high-affinity choline transporter CHT1 and choline acetyltransferase in neurons of superior cervical ganglia. Mol Cell Neurosci (2005) 0.82
HIF1α and pancreatic β-cell development. FASEB J (2012) 0.82
Fetal pancreas transplants are dependent on prolactin for their development and prevent type 1 diabetes in syngeneic but not allogeneic mice. Diabetes (2013) 0.81
mTOR-dependent proliferation defect in human ES-derived neural stem cells affected by myotonic dystrophy type 1. J Cell Sci (2013) 0.81
Development of the pancreas in medaka. Mech Dev (2002) 0.80
Role for VPAC2 receptor-mediated signals in pancreas development. Diabetes (2003) 0.80
Human liver cells expressing albumin and mesenchymal characteristics give rise to insulin-producing cells. J Transplant (2011) 0.80
Diabetes in very young children and mutations in the insulin-secreting cell potassium channel genes: therapeutic consequences. Endocr Dev (2007) 0.79
Innate and adaptive immunity to human beta cell lines: implications for beta cell therapy. Diabetologia (2016) 0.78
FGFR1-IIIb is a putative marker of pancreatic progenitor cells. Mech Dev (2002) 0.78
Xenotropic retrovirus Bxv1 in human pancreatic β cell lines. J Clin Invest (2016) 0.76
Directed pancreatic acinar differentiation of mouse embryonic stem cells via embryonic signalling molecules and exocrine transcription factors. PLoS One (2013) 0.76
Correction: ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target. Cancer Cell Int (2011) 0.75
Erratum. Sulfonylurea Therapy Benefits Neurological and Psychomotor Functions in Patients With Neonatal Diabetes Owing to Potassium Channel Mutations. Diabetes Care 2015;38:2033-2041. Diabetes Care (2016) 0.75
[First immortalised cell lines phenotypically and functionally equivalent to human insulin-secreting pancreatic beta cells]. Med Sci (Paris) (2012) 0.75