Published in Chromosome Res on January 01, 2006
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
A map of open chromatin in human pancreatic islets. Nat Genet (2010) 6.75
Concern Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules. Proc Natl Acad Sci U S A (2008) 4.31
Identification of higher-order functional domains in the human ENCODE regions. Genome Res (2007) 2.62
The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription. Mol Cell Biol (2007) 1.82
Genetic and epigenetic mechanisms of gene regulation during lens development. Prog Retin Eye Res (2007) 1.56
Global chromatin domain organization of the Drosophila genome. PLoS Genet (2008) 1.45
The B-type lamin is required for somatic repression of testis-specific gene clusters. Proc Natl Acad Sci U S A (2009) 1.37
Gene positioning. Cold Spring Harb Perspect Biol (2010) 1.12
Disruption of topoisomerase II perturbs pairing in drosophila cell culture. Genetics (2007) 1.08
Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factors. BMC Dev Biol (2008) 1.06
Novel repression of Kcc2 transcription by REST-RE-1 controls developmental switch in neuronal chloride. J Neurosci (2009) 1.01
DNA methylation pattern as important epigenetic criterion in cancer. Genet Res Int (2013) 1.00
Epigenetic regulation of promiscuous gene expression in thymic medullary epithelial cells. Proc Natl Acad Sci U S A (2010) 0.96
Hormone response element binding proteins: novel regulators of vitamin D and estrogen signaling. Steroids (2011) 0.95
Prediction of epigenetically regulated genes in breast cancer cell lines. BMC Bioinformatics (2010) 0.95
A novel role for the Aurora B kinase in epigenetic marking of silent chromatin in differentiated postmitotic cells. EMBO J (2007) 0.94
Nucleoporin mediated nuclear positioning and silencing of HMR. PLoS One (2011) 0.85
Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells. Mol Cell Biol (2013) 0.85
Estrogen represses gene expression through reconfiguring chromatin structures. Nucleic Acids Res (2013) 0.85
Mechanism-anchored profiling derived from epigenetic networks predicts outcome in acute lymphoblastic leukemia. BMC Bioinformatics (2009) 0.84
DNA methylation-histone modification relationships across the desmin locus in human primary cells. BMC Mol Biol (2009) 0.84
Brain region-specific expression of Fxyd1, an Mecp2 target gene, is regulated by epigenetic mechanisms. J Neurosci Res (2011) 0.81
Histone Deacetylase (HDAC) Inhibitors - emerging roles in neuronal memory, learning, synaptic plasticity and neural regeneration. Curr Neuropharmacol (2016) 0.78
In situ methods to localize transgenes and transcripts in interphase nuclei: a tool for transgenic plant research. Plant Methods (2006) 0.77
The influence of DNA sequence on epigenome-induced pathologies. Epigenetics Chromatin (2012) 0.77
Differential requirement of a distal regulatory region for pre-initiation complex formation at globin gene promoters. Nucleic Acids Res (2009) 0.76
Natural compound-derived epigenetic regulators targeting epigenetic readers, writers and erasers. Curr Top Med Chem (2016) 0.75
Differential activity of clustered genes in Arabidopsis thaliana. Dokl Biochem Biophys (2011) 0.75
Position-independent, high-level expression of the human beta-globin gene in transgenic mice. Cell (1987) 15.79
Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell (1990) 12.50
The human transcriptome map: clustering of highly expressed genes in chromosomal domains. Science (2001) 12.35
Looping and interaction between hypersensitive sites in the active beta-globin locus. Mol Cell (2002) 11.35
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. Mol Cell (2003) 11.33
Active genes dynamically colocalize to shared sites of ongoing transcription. Nat Genet (2004) 9.57
Evidence for large domains of similarly expressed genes in the Drosophila genome. J Biol (2002) 9.31
Interchromosomal associations between alternatively expressed loci. Nature (2005) 7.45
Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes. Dev Cell (2003) 7.11
Long-range chromatin regulatory interactions in vivo. Nat Genet (2002) 6.55
The glucocorticoid receptor: rapid exchange with regulatory sites in living cells. Science (2000) 6.17
Chromatin decondensation and nuclear reorganization of the HoxB locus upon induction of transcription. Genes Dev (2004) 5.11
Interphase chromosomes undergo constrained diffusional motion in living cells. Curr Biol (1997) 5.00
Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell (2004) 4.95
Heterochromatin and gene expression in Drosophila. Annu Rev Genet (1995) 4.90
Maintenance of stable heterochromatin domains by dynamic HP1 binding. Science (2003) 4.74
X-ray structure of a tetranucleosome and its implications for the chromatin fibre. Nature (2005) 4.58
Position effect variegation in Drosophila is associated with an altered chromatin structure. Genes Dev (1995) 4.41
Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci. EMBO J (2001) 4.28
Life on a planet of its own: regulation of RNA polymerase I transcription in the nucleolus. Genes Dev (2003) 3.85
Nucleosome arrays reveal the two-start organization of the chromatin fiber. Science (2004) 3.83
Perinuclear localization of chromatin facilitates transcriptional silencing. Nature (1998) 3.68
Human CD2 3'-flanking sequences confer high-level, T cell-specific, position-independent gene expression in transgenic mice. Cell (1989) 3.48
Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques. Proc Natl Acad Sci U S A (2004) 2.99
Pushing the envelope: structure, function, and dynamics of the nuclear periphery. Annu Rev Cell Dev Biol (2005) 2.95
Evolution and functional classification of vertebrate gene deserts. Genome Res (2004) 2.92
Lysine acetylation and the bromodomain: a new partnership for signaling. Bioessays (2004) 2.84
Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription. Cell (1996) 2.77
The higher-order structure of chromatin: evidence for a helical ribbon arrangement. J Cell Biol (1984) 2.68
Recent advances in X-chromosome inactivation. Curr Opin Cell Biol (2004) 2.65
Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells. Science (2003) 2.61
The insulation of genes from external enhancers and silencing chromatin. Proc Natl Acad Sci U S A (2002) 2.60
The transcription cycle of RNA polymerase II in living cells. J Cell Biol (2002) 2.59
Tissue-specific factors additively increase the probability of the all-or-none formation of a hypersensitive site. EMBO J (1996) 2.45
Locus control region function and heterochromatin-induced position effect variegation. Science (1996) 2.42
Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. Proc Natl Acad Sci U S A (1999) 2.39
Setting the boundaries of chromatin domains and nuclear organization. Cell (2002) 2.27
The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus. Mol Cell (1998) 2.22
Heterochromatin and gene regulation in Drosophila. Curr Opin Genet Dev (1996) 2.16
The role of enhancers as centres for general transcription factor recruitment. Trends Biochem Sci (2005) 2.14
Higher-order structure of chromatin and chromosomes. Curr Opin Genet Dev (2001) 2.06
Spatial relationship between transcription sites and chromosome territories. J Cell Biol (1999) 1.96
Spatial organization of active and inactive genes and noncoding DNA within chromosome territories. J Cell Biol (2002) 1.92
The effect of distance on long-range chromatin interactions. Mol Cell (1997) 1.90
Cellular stress and nucleolar function. Cell Cycle (2005) 1.88
Clusters of co-expressed genes in mammalian genomes are conserved by natural selection. Mol Biol Evol (2004) 1.86
Regulation of heterochromatin by histone methylation and small RNAs. Curr Opin Cell Biol (2004) 1.72
Formation of an active tissue-specific chromatin domain initiated by epigenetic marking at the embryonic stem cell stage. Mol Cell Biol (2005) 1.62
Identification of a conserved erythroid specific domain of histone acetylation across the alpha-globin gene cluster. Proc Natl Acad Sci U S A (2001) 1.57
Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene. Cell (2000) 1.57
Large-scale chromatin structure and function. Curr Opin Cell Biol (1999) 1.57
Functional gene expression domains: defining the functional unit of eukaryotic gene regulation. Bioessays (2000) 1.56
The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region. EMBO J (1993) 1.46
Methylation of histones: playing memory with DNA. Curr Opin Cell Biol (2005) 1.40
Bystander gene activation by a locus control region. EMBO J (2004) 1.38
Common effects of acidic activators on large-scale chromatin structure and transcription. Mol Cell Biol (2005) 1.16
The nucleolus and transcription of ribosomal genes. Biol Cell (2004) 1.13
Insulator dynamics and the setting of chromatin domains. Bioessays (2004) 1.11
Chromosomal clustering of a human transcriptome reveals regulatory background. BMC Bioinformatics (2005) 1.11
Reconstitution of hyperacetylated, DNase I-sensitive chromatin characterized by high conformational flexibility of nucleosomal DNA. Proc Natl Acad Sci U S A (1998) 1.07
Analysis of mice with single and multiple copies of transgenes reveals a novel arrangement for the lambda5-VpreB1 locus control region. Mol Cell Biol (1999) 1.01
From snapshots to moving pictures: new perspectives on nuclear organization. Trends Cell Biol (2001) 0.99
Path to equality strewn with roX. Dev Biol (2004) 0.97
Analyzing heterochromatin formation using chromosome 4 of Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (2004) 0.95
Transcription factories: quantitative studies of nanostructures in the mammalian nucleus. Chromosome Res (2003) 0.95
Transcription and the territory: the ins and outs of gene positioning. Trends Genet (2003) 0.94
The chicken lysozyme chromatin domain contains a second, widely expressed gene. Nucleic Acids Res (2002) 0.91
Mapping and functional analysis of regulatory sequences in the mouse lambda5-VpreB1 domain. Mol Immunol (2005) 0.89
Gene autonomy: positions, please... Nature (2003) 0.83
Transposable elements and the evolution of heterochromatin. Soc Gen Physiol Ser (1994) 0.83