| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Efferent vagal fibre stimulation blunts nuclear factor-kappaB activation and protects against hypovolemic hemorrhagic shock.
|
Circulation
|
2003
|
2.03
|
|
2
|
Activation of an efferent cholinergic pathway produces strong protection against myocardial ischemia/reperfusion injury in rats.
|
Crit Care Med
|
2005
|
1.96
|
|
3
|
Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial.
|
Ann Intern Med
|
2007
|
1.76
|
|
4
|
The effect of PDRN, an adenosine receptor A2A agonist, on the healing of chronic diabetic foot ulcers: results of a clinical trial.
|
J Clin Endocrinol Metab
|
2014
|
1.75
|
|
5
|
Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.
|
Endocrinology
|
2005
|
1.63
|
|
6
|
Protective effects of melanocortins on short-term changes in a rat model of traumatic brain injury*.
|
Crit Care Med
|
2012
|
1.45
|
|
7
|
Nuclear factor kappa-B blockade reduces skeletal muscle degeneration and enhances muscle function in Mdx mice.
|
Exp Neurol
|
2006
|
1.39
|
|
8
|
Activation of the cholinergic anti-inflammatory pathway reduces NF-kappab activation, blunts TNF-alpha production, and protects againts splanchic artery occlusion shock.
|
Shock
|
2006
|
1.29
|
|
9
|
Recombinant human erythropoietin stimulates angiogenesis and wound healing in the genetically diabetic mouse.
|
Diabetes
|
2004
|
1.29
|
|
10
|
Lipid peroxidation inhibition blunts nuclear factor-kappaB activation, reduces skeletal muscle degeneration, and enhances muscle function in mdx mice.
|
Am J Pathol
|
2006
|
1.24
|
|
11
|
VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice.
|
FASEB J
|
2007
|
1.18
|
|
12
|
Effects of the phytoestrogen genistein on some predictors of cardiovascular risk in osteopenic, postmenopausal women: a two-year randomized, double-blind, placebo-controlled study.
|
J Clin Endocrinol Metab
|
2007
|
1.18
|
|
13
|
Recombinant human erythropoietin improves angiogenesis and wound healing in experimental burn wounds.
|
Crit Care Med
|
2006
|
1.12
|
|
14
|
Breast safety and efficacy of genistein aglycone for postmenopausal bone loss: a follow-up study.
|
J Clin Endocrinol Metab
|
2008
|
1.10
|
|
15
|
Attenuated cerulein-induced pancreatitis in nuclear factor-kappaB-deficient mice.
|
Lab Invest
|
2003
|
1.10
|
|
16
|
Polydeoxyribonucleotide stimulates angiogenesis and wound healing in the genetically diabetic mouse.
|
Wound Repair Regen
|
2008
|
1.08
|
|
17
|
OPG and sRANKL serum concentrations in osteopenic, postmenopausal women after 2-year genistein administration.
|
J Bone Miner Res
|
2008
|
1.00
|
|
18
|
Protective effect of genistein aglycone on the development of osteonecrosis of the femoral head and secondary osteoporosis induced by methylprednisolone in rats.
|
J Endocrinol
|
2009
|
0.99
|
|
19
|
Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A(₂A) receptor.
|
Arthritis Rheum
|
2011
|
0.99
|
|
20
|
Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 2-year randomized, double-blind, placebo-controlled study.
|
Menopause
|
2009
|
0.98
|
|
21
|
Flavocoxid, a dual inhibitor of COX-2 and 5-LOX of natural origin, attenuates the inflammatory response and protects mice from sepsis.
|
Crit Care
|
2012
|
0.98
|
|
22
|
Angiopoietin-1 gene transfer improves impaired wound healing in genetically diabetic mice without increasing VEGF expression.
|
Clin Sci (Lond)
|
2008
|
0.95
|
|
23
|
Activation of adenosine A2A receptors restores the altered cell-cycle machinery during impaired wound healing in genetically diabetic mice.
|
Surgery
|
2010
|
0.94
|
|
24
|
Simvastatin enhances VEGF production and ameliorates impaired wound healing in experimental diabetes.
|
Pharmacol Res
|
2008
|
0.94
|
|
25
|
Polydeoxyribonucleotide (PDRN): a safe approach to induce therapeutic angiogenesis in peripheral artery occlusive disease and in diabetic foot ulcers.
|
Cardiovasc Hematol Agents Med Chem
|
2009
|
0.93
|
|
26
|
Genistein in the metabolic syndrome: results of a randomized clinical trial.
|
J Clin Endocrinol Metab
|
2013
|
0.93
|
|
27
|
Systemic administration of high-molecular weight hyaluronan stimulates wound healing in genetically diabetic mice.
|
Biochim Biophys Acta
|
2011
|
0.92
|
|
28
|
Inhibition of nuclear factor-kappaB activation by IRFI 042, protects against endotoxin-induced shock.
|
Cardiovasc Res
|
2002
|
0.92
|
|
29
|
High mobility group box-1 expression correlates with poor outcome in lung injury patients.
|
Pharmacol Res
|
2009
|
0.92
|
|
30
|
Genistein aglycone does not affect thyroid function: results from a three-year, randomized, double-blind, placebo-controlled trial.
|
J Clin Endocrinol Metab
|
2010
|
0.90
|
|
31
|
Vagus nerve mediates the protective effects of melanocortins against cerebral and systemic damage after ischemic stroke.
|
J Cereb Blood Flow Metab
|
2008
|
0.90
|
|
32
|
Adenosine receptor stimulation by polynucleotides (PDRN) reduces inflammation in experimental periodontitis.
|
J Clin Periodontol
|
2012
|
0.90
|
|
33
|
Effects of the phytoestrogen genistein on hot flushes, endometrium, and vaginal epithelium in postmenopausal women: a 1-year randomized, double-blind, placebo-controlled study.
|
Menopause
|
2007
|
0.90
|
|
34
|
Effects of Serenoa repens, selenium and lycopene (Profluss®) on chronic inflammation associated with benign prostatic hyperplasia: results of "FLOG" (Flogosis and Profluss in Prostatic and Genital Disease), a multicentre Italian study.
|
Int Braz J Urol
|
2013
|
0.88
|
|
35
|
Modulation of IL-1 beta gene expression by lipid peroxidation inhibition after kainic acid-induced rat brain injury.
|
Exp Neurol
|
2004
|
0.88
|
|
36
|
Gene transfer of IkappaBalpha limits infarct size in a mouse model of myocardial ischemia-reperfusion injury.
|
Lab Invest
|
2003
|
0.87
|
|
37
|
Neuroprotection in focal cerebral ischemia owing to delayed treatment with melanocortins.
|
Eur J Pharmacol
|
2007
|
0.86
|
|
38
|
Polydeoxyribonucleotide administration improves the intra-testicular vascularization in rat experimental varicocele.
|
Fertil Steril
|
2011
|
0.86
|
|
39
|
Broad therapeutic treatment window of [Nle(4), D-Phe(7)]alpha-melanocyte-stimulating hormone for long-lasting protection against ischemic stroke, in Mongolian gerbils.
|
Eur J Pharmacol
|
2006
|
0.86
|
|
40
|
Relaxin improves multiple markers of wound healing and ameliorates the disturbed healing pattern of genetically diabetic mice.
|
Clin Sci (Lond)
|
2013
|
0.85
|
|
41
|
Polydeoxyribonucleotide improves angiogenesis and wound healing in experimental thermal injury.
|
Crit Care Med
|
2008
|
0.85
|
|
42
|
Polydeoxyribonucleotide (PDRN) restores blood flow in an experimental model of peripheral artery occlusive disease.
|
J Vasc Surg
|
2008
|
0.85
|
|
43
|
Inhibitors of apoptosis proteins in experimental benign prostatic hyperplasia: effects of serenoa repens, selenium and lycopene.
|
J Biomed Sci
|
2014
|
0.84
|
|
44
|
Effects of aglycone genistein in a rat experimental model of postmenopausal metabolic syndrome.
|
J Endocrinol
|
2008
|
0.84
|
|
45
|
Melanocortins protect against multiple organ dysfunction syndrome in mice.
|
Br J Pharmacol
|
2011
|
0.83
|
|
46
|
Melanocortin MC₄ receptor agonists counteract late inflammatory and apoptotic responses and improve neuronal functionality after cerebral ischemia.
|
Eur J Pharmacol
|
2011
|
0.83
|
|
47
|
Crucial role of nuclear factor-kappaB in neointimal hyperplasia of the mouse carotid artery after interruption of blood flow.
|
Atherosclerosis
|
2003
|
0.83
|
|
48
|
Effect of Serenoa repens, lycopene, and selenium on proinflammatory phenotype activation: an in vitro and in vivo comparison study.
|
Urology
|
2010
|
0.82
|
|
49
|
Functional recovery after delayed treatment of ischemic stroke with melanocortins is associated with overexpression of the activity-dependent gene Zif268.
|
Brain Behav Immun
|
2009
|
0.82
|
|
50
|
Protective effects of antioxidant raxofelast in alcohol-induced liver disease in mice.
|
Pharmacology
|
2004
|
0.80
|
|
51
|
The combination of Serenoa repens, selenium and lycopene is more effective than serenoa repens alone to prevent hormone dependent prostatic growth.
|
J Urol
|
2011
|
0.80
|
|
52
|
Lipid peroxidation triggers both c-Jun N-terminal kinase (JNK) and extracellular-regulated kinase (ERK) activation and neointimal hyperplasia induced by cessation of blood flow in the mouse carotid artery.
|
Atherosclerosis
|
2005
|
0.80
|
|
53
|
Melanocortins as potential therapeutic agents in severe hypoxic conditions.
|
Front Neuroendocrinol
|
2012
|
0.80
|
|
54
|
Lipid peroxidation activates mitogen-activated protein kinases in testicular ischemia-reperfusion injury.
|
J Urol
|
2006
|
0.79
|
|
55
|
Genistein and endothelial function in postmenopausal women with metabolic syndrome.
|
Eur J Clin Invest
|
2013
|
0.79
|
|
56
|
Lipid peroxidation inhibition by raxofelast improves angiogenesis and wound healing in experimental burn wounds.
|
Shock
|
2005
|
0.78
|
|
57
|
Levetiracetam protects against kainic acid-induced toxicity.
|
Life Sci
|
2004
|
0.78
|
|
58
|
Treatment of cerebral ischemia with melanocortins acting at MC4 receptors induces marked neurogenesis and long-lasting functional recovery.
|
Acta Neuropathol
|
2011
|
0.78
|
|
59
|
Genistein aglycone, a soy-derived isoflavone, improves skin changes induced by ovariectomy in rats.
|
Br J Pharmacol
|
2012
|
0.78
|
|
60
|
Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes.
|
J Nutr Metab
|
2012
|
0.77
|
|
61
|
Genistein administration & climacteric symptoms: from plasma levels to biological activity.
|
Indian J Med Res
|
2007
|
0.75
|
|
62
|
Porcine derived relaxin stimulates new vessel formation and improves the disturbed wound healing of the genetically diabetic mice.
|
Ital J Anat Embryol
|
2013
|
0.75
|
|
63
|
BAY 11-7082 inhibits the NF-kB and NLRP3 inflammasome pathways and protects against IMQ-induced psoriasis.
|
Clin Sci (Lond)
|
2017
|
0.75
|
|
64
|
Inhibition of lipid peroxidation by IRFI 042, a vitamin E analogue, decreases monensin cardiotoxicity in chicks.
|
Toxicol Appl Pharmacol
|
2005
|
0.75
|
|
65
|
Anti-inflammatory effects of the methanol extract of Sedum telephium ssp. maximum in lipopolysaccharide- stimulated rat peritoneal macrophages.
|
Pharmacology
|
2008
|
0.75
|
|
66
|
Ileocystoplasty in rats: metabolic, renal and enteropatch changes in a mid- and long-term follow-up.
|
Urol Int
|
2011
|
0.75
|