Multiple Wnts and frizzled receptors regulate anteriorly directed cell and growth cone migrations in Caenorhabditis elegans.

PubWeight™: 1.61‹?› | Rank: Top 4%

🔗 View Article (PMID 16516839)

Published in Dev Cell on March 01, 2006

Authors

Chun-Liang Pan1, James Endres Howell, Scott G Clark, Massimo Hilliard, Shaun Cordes, Cornelia I Bargmann, Gian Garriga

Author Affiliations

1: Helen Wills Neuroscience Institute and Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.

Articles citing this

C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/Wntless. Dev Cell (2007) 2.10

Genetics and cell biology of building specific synaptic connectivity. Annu Rev Neurosci (2010) 1.71

Opposing Wnt pathways orient cell polarity during organogenesis. Cell (2008) 1.70

LIN-44/Wnt directs dendrite outgrowth through LIN-17/Frizzled in C. elegans Neurons. PLoS Biol (2011) 1.58

Axon guidance genes identified in a large-scale RNAi screen using the RNAi-hypersensitive Caenorhabditis elegans strain nre-1(hd20) lin-15b(hd126). Proc Natl Acad Sci U S A (2007) 1.48

Neurons refine the Caenorhabditis elegans body plan by directing axial patterning by Wnts. PLoS Biol (2013) 1.44

Constitutive gene expression and the specification of tissue identity in adult planarian biology. Trends Genet (2011) 1.30

Navigating intermediate targets: the nervous system midline. Cold Spring Harb Perspect Biol (2010) 1.21

Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases. Neural Dev (2009) 1.21

Complex network of Wnt signaling regulates neuronal migrations during Caenorhabditis elegans development. Genetics (2008) 1.20

Frizzled-5, a receptor for the synaptic organizer Wnt7a, regulates activity-mediated synaptogenesis. Development (2010) 1.18

The tripartite motif protein MADD-2 functions with the receptor UNC-40 (DCC) in Netrin-mediated axon attraction and branching. Dev Cell (2010) 1.10

A Wnt-Frz/Ror-Dsh pathway regulates neurite outgrowth in Caenorhabditis elegans. PLoS Genet (2010) 1.09

Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein. Development (2011) 1.09

WNTs in synapse formation and neuronal circuitry. EMBO J (2012) 1.07

Wnt signal from multiple tissues and lin-3/EGF signal from the gonad maintain vulval precursor cell competence in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2007) 1.04

The Caenorhabditis elegans epidermis as a model skin. II: differentiation and physiological roles. Wiley Interdiscip Rev Dev Biol (2012) 1.02

Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells. EMBO J (2010) 1.02

A C. elegans Myc-like network cooperates with semaphorin and Wnt signaling pathways to control cell migration. Dev Biol (2007) 1.02

Wnt-Ror signaling to SIA and SIB neurons directs anterior axon guidance and nerve ring placement in C. elegans. Development (2009) 1.01

Live imaging of cellular dynamics during Caenorhabditis elegans postembryonic development. Nat Protoc (2012) 1.01

The Nesprin family member ANC-1 regulates synapse formation and axon termination by functioning in a pathway with RPM-1 and β-Catenin. PLoS Genet (2014) 0.98

VANG-1 and PRKL-1 cooperate to negatively regulate neurite formation in Caenorhabditis elegans. PLoS Genet (2011) 0.98

A beta-catenin-dependent Wnt pathway mediates anteroposterior axon guidance in C. elegans motor neurons. PLoS One (2009) 0.96

Wnt signaling controls the stem cell-like asymmetric division of the epithelial seam cells during C. elegans larval development. Dev Biol (2010) 0.94

The role of C. elegans Ena/VASP homolog UNC-34 in neuronal polarity and motility. Dev Biol (2010) 0.93

Transmembrane proteins UNC-40/DCC, PTP-3/LAR, and MIG-21 control anterior-posterior neuroblast migration with left-right functional asymmetry in Caenorhabditis elegans. Genetics (2012) 0.92

Experimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity. Biol Open (2013) 0.92

β-catenin-dependent Wnt signaling in C. elegans: teaching an old dog a new trick. Cold Spring Harb Perspect Biol (2012) 0.91

MIG-32 and SPAT-3A are PRC1 homologs that control neuronal migration in Caenorhabditis elegans. Development (2009) 0.91

Multiple Wnts redundantly control polarity orientation in Caenorhabditis elegans epithelial stem cells. PLoS Genet (2011) 0.89

Guidance of longitudinally projecting axons in the developing central nervous system. Front Mol Neurosci (2012) 0.85

C. elegans fmi-1/flamingo and Wnt pathway components interact genetically to control the anteroposterior neurite growth of the VD GABAergic neurons. Dev Biol (2013) 0.85

SAX-3 (Robo) and UNC-40 (DCC) regulate a directional bias for axon guidance in response to multiple extracellular cues. PLoS One (2014) 0.83

Longitudinal axons are guided by Slit/Robo signals from the floor plate. Cell Adh Migr (2010) 0.83

Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans. Dev Biol (2012) 0.83

Wnt-signaling and planar cell polarity genes regulate axon guidance along the anteroposterior axis in C. elegans. Dev Neurobiol (2013) 0.83

Sonic hedgehog and Wnt: antagonists in morphogenesis but collaborators in axon guidance. Front Cell Neurosci (2013) 0.82

Wnt signaling in Pristionchus pacificus gonadal arm extension and the evolution of organ shape. Proc Natl Acad Sci U S A (2008) 0.81

Axon guidance and injury-lessons from Wnts and Wnt signaling. Curr Opin Neurobiol (2014) 0.81

Netrins and Wnts function redundantly to regulate antero-posterior and dorso-ventral guidance in C. elegans. PLoS Genet (2014) 0.81

RPM-1 is localized to distinct subcellular compartments and regulates axon length in GABAergic motor neurons. Neural Dev (2014) 0.81

A TOCA/CDC-42/PAR/WAVE functional module required for retrograde endocytic recycling. Proc Natl Acad Sci U S A (2015) 0.80

The T-box gene tbx-2, the homeobox gene egl-5 and the asymmetric cell division gene ham-1 specify neural fate in the HSN/PHB lineage. Genetics (2008) 0.79

The conserved transmembrane RING finger protein PLR-1 downregulates Wnt signaling by reducing Frizzled, Ror and Ryk cell-surface levels in C. elegans. Development (2014) 0.79

Two Wnts instruct topographic synaptic innervation in C. elegans. Cell Rep (2013) 0.78

UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit. Development (2012) 0.78

Calpain activation by Wingless-type murine mammary tumor virus integration site family, member 5A (Wnt5a) promotes axonal growth. J Biol Chem (2010) 0.78

Nonautonomous regulation of neuronal migration by insulin signaling, DAF-16/FOXO, and PAK-1. Cell Rep (2013) 0.78

Dishevelled attenuates the repelling activity of Wnt signaling during neurite outgrowth in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2015) 0.78

EGL-20/Wnt and MAB-5/Hox Act Sequentially to Inhibit Anterior Migration of Neuroblasts in C. elegans. PLoS One (2016) 0.77

Autonomous and nonautonomous regulation of Wnt-mediated neuronal polarity by the C. elegans Ror kinase CAM-1. Dev Biol (2015) 0.77

The Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegans. Genetics (2016) 0.76

MTM-6, a phosphoinositide phosphatase, is required to promote synapse formation in Caenorhabditis elegans. PLoS One (2014) 0.76

Neuronal migration is regulated by endogenous RNAi and chromatin-binding factor ZFP-1/AF10 in Caenorhabditis elegans. Genetics (2014) 0.76

Orchestrating A/P and D/V guidance - A Wnt/Netrin tale. Worm (2016) 0.76

Pioneer Axon Navigation Is Controlled by AEX-3, a Guanine Nucleotide Exchange Factor for RAB-3 in Caenorhabditis elegans. Genetics (2016) 0.75

The Caenorhabditis elegans NF2/Merlin Molecule NFM-1 Non-autonomously Regulates Neuroblast Migration and Interacts Genetically with the Guidance Cue SLT-1/Slit. Genetics (2016) 0.75

Articles by these authors

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature (2002) 16.52

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature (2003) 14.49

Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat Methods (2009) 13.39

Diverse somatic mutation patterns and pathway alterations in human cancers. Nature (2010) 10.83

Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans. Nature (2007) 6.17

Optimization of a GCaMP calcium indicator for neural activity imaging. J Neurosci (2012) 6.09

Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature (2004) 5.09

A circuit for navigation in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2005) 5.06

Comparing genomic expression patterns across species identifies shared transcriptional profile in aging. Nat Genet (2004) 4.77

Microfluidics for in vivo imaging of neuronal and behavioral activity in Caenorhabditis elegans. Nat Methods (2007) 4.70

Pathogenic bacteria induce aversive olfactory learning in Caenorhabditis elegans. Nature (2005) 4.30

A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans. Nature (2009) 4.05

GFP Reconstitution Across Synaptic Partners (GRASP) defines cell contacts and synapses in living nervous systems. Neuron (2008) 3.81

Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones. J Cell Sci (2004) 3.31

Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons. Neuron (2002) 3.17

A distributed chemosensory circuit for oxygen preference in C. elegans. PLoS Biol (2006) 2.95

Synaptic specificity is generated by the synaptic guidepost protein SYG-2 and its receptor, SYG-1. Cell (2004) 2.85

Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics. Front Mol Neurosci (2013) 2.79

Serotonin and the neuropeptide PDF initiate and extend opposing behavioral states in C. elegans. Cell (2013) 2.77

An optimized fluorescent probe for visualizing glutamate neurotransmission. Nat Methods (2013) 2.75

A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response. J Cell Biol (2002) 2.72

A central role of the BK potassium channel in behavioral responses to ethanol in C. elegans. Cell (2003) 2.72

Social feeding in Caenorhabditis elegans is induced by neurons that detect aversive stimuli. Nature (2002) 2.61

Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans. Proc Natl Acad Sci U S A (2007) 2.56

Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2003) 2.50

Quantitative mapping of a digenic behavioral trait implicates globin variation in C. elegans sensory behaviors. Neuron (2009) 2.44

UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formation. Nat Neurosci (2006) 2.42

An innexin-dependent cell network establishes left-right neuronal asymmetry in C. elegans. Cell (2007) 2.41

A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling. Genes Dev (2004) 2.35

Catecholamine receptor polymorphisms affect decision-making in C. elegans. Nature (2011) 2.32

The immunoglobulin superfamily protein SYG-1 determines the location of specific synapses in C. elegans. Cell (2003) 2.30

A behavioral switch: cGMP and PKC signaling in olfactory neurons reverses odor preference in C. elegans. Neuron (2008) 2.26

Fast multicolor 3D imaging using aberration-corrected multifocus microscopy. Nat Methods (2012) 2.25

SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans. EMBO Rep (2001) 2.22

Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes. Nature (2011) 2.18

Mechanosensory neurite termination and tiling depend on SAX-2 and the SAX-1 kinase. Neuron (2004) 2.18

The cyclic GMP-dependent protein kinase EGL-4 regulates olfactory adaptation in C. elegans. Neuron (2002) 2.15

Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases. Neuron (2009) 2.14

C. elegans responds to chemical repellents by integrating sensory inputs from the head and the tail. Curr Biol (2002) 2.12

C. elegans AP-2 and retromer control Wnt signaling by regulating mig-14/Wntless. Dev Cell (2007) 2.10

Innate immunity in Caenorhabditis elegans is regulated by neurons expressing NPR-1/GPCR. Science (2008) 2.09

Homologous gene targeting in Caenorhabditis elegans by biolistic transformation. Nucleic Acids Res (2004) 2.06

Oxytocin/vasopressin-related peptides have an ancient role in reproductive behavior. Science (2012) 2.03

The netrin receptor UNC-40/DCC stimulates axon attraction and outgrowth through enabled and, in parallel, Rac and UNC-115/AbLIM. Neuron (2003) 1.95

High-content behavioral analysis of Caenorhabditis elegans in precise spatiotemporal chemical environments. Nat Methods (2011) 1.92

Neuropeptide feedback modifies odor-evoked dynamics in Caenorhabditis elegans olfactory neurons. Nat Neurosci (2010) 1.86

Wnt signals and frizzled activity orient anterior-posterior axon outgrowth in C. elegans. Dev Cell (2006) 1.85

Wnt signaling establishes anteroposterior neuronal polarity and requires retromer in C. elegans. Development (2006) 1.79

Otx/otd homeobox genes specify distinct sensory neuron identities in C. elegans. Dev Cell (2003) 1.71

Abl kinase inhibits the engulfment of apoptotic [corrected] cells in Caenorhabditis elegans. PLoS Biol (2009) 1.69

Specific polyunsaturated fatty acids drive TRPV-dependent sensory signaling in vivo. Cell (2004) 1.67

Hierarchical assembly of presynaptic components in defined C. elegans synapses. Nat Neurosci (2006) 1.66

MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrin. Curr Biol (2006) 1.61

The C. elegans MELK ortholog PIG-1 regulates cell size asymmetry and daughter cell fate in asymmetric neuroblast divisions. Development (2006) 1.55

Shared receptors in axon guidance: SAX-3/Robo signals via UNC-34/Enabled and a Netrin-independent UNC-40/DCC function. Nat Neurosci (2002) 1.52

Talin loss-of-function uncovers roles in cell contractility and migration in C. elegans. J Cell Sci (2003) 1.51

Roles for Caenorhabditis elegans rad-51 in meiosis and in resistance to ionizing radiation during development. Genetics (2002) 1.45

Caenorhabditis elegans WASP and Ena/VASP proteins play compensatory roles in morphogenesis and neuronal cell migration. Genetics (2004) 1.41

TRP channels in C. elegans. Annu Rev Physiol (2006) 1.39

Laser microsurgery in Caenorhabditis elegans. Methods Cell Biol (2012) 1.38

The Caenorhabditis elegans Ror RTK CAM-1 inhibits EGL-20/Wnt signaling in cell migration. Genetics (2004) 1.36

Behavioral choice between conflicting alternatives is regulated by a receptor guanylyl cyclase, GCY-28, and a receptor tyrosine kinase, SCD-2, in AIA interneurons of Caenorhabditis elegans. J Neurosci (2011) 1.36

Neuromodulatory state and sex specify alternative behaviors through antagonistic synaptic pathways in C. elegans. Neuron (2012) 1.33

Genetic contributions to behavioural diversity at the gene-environment interface. Nat Rev Genet (2011) 1.32

Hypoxia and the HIF-1 transcriptional pathway reorganize a neuronal circuit for oxygen-dependent behavior in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2008) 1.30

C. elegans VAB-8 and UNC-73 regulate the SAX-3 receptor to direct cell and growth-cone migrations. Nat Neurosci (2007) 1.26

UNC-33 (CRMP) and ankyrin organize microtubules and localize kinesin to polarize axon-dendrite sorting. Nat Neurosci (2011) 1.25

Invertebrate nociception: behaviors, neurons and molecules. J Neurobiol (2004) 1.25

Inducible and titratable silencing of Caenorhabditis elegans neurons in vivo with histamine-gated chloride channels. Proc Natl Acad Sci U S A (2014) 1.21

Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans. Neural Dev (2007) 1.18

Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36. Nat Neurosci (2009) 1.18

Transcriptional regulation and stabilization of left-right neuronal identity in C. elegans. Genes Dev (2009) 1.17

High-throughput imaging of neuronal activity in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2013) 1.17

Genetic analysis of the myotubularin family of phosphatases in Caenorhabditis elegans. J Biol Chem (2003) 1.13

Microtubule-based localization of a synaptic calcium-signaling complex is required for left-right neuronal asymmetry in C. elegans. Development (2011) 1.11

The tripartite motif protein MADD-2 functions with the receptor UNC-40 (DCC) in Netrin-mediated axon attraction and branching. Dev Cell (2010) 1.10

Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase. Science (2004) 1.09

UNC-97/PINCH is involved in the assembly of integrin cell adhesion complexes in Caenorhabditis elegans body wall muscle. Dev Biol (2007) 1.07

The Flamingo ortholog FMI-1 controls pioneer-dependent navigation of follower axons in C. elegans. Development (2010) 1.05

Discovering cancer genes by integrating network and functional properties. BMC Med Genomics (2009) 1.05

Specific expression of channelrhodopsin-2 in single neurons of Caenorhabditis elegans. PLoS One (2012) 1.04

Asymmetric divisions, aggresomes and apoptosis. Trends Cell Biol (2008) 1.04

The claudin superfamily protein nsy-4 biases lateral signaling to generate left-right asymmetry in C. elegans olfactory neurons. Neuron (2006) 1.02

Mu2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans. J Cell Biol (2008) 1.01

Wnt-Ror signaling to SIA and SIB neurons directs anterior axon guidance and nerve ring placement in C. elegans. Development (2009) 1.01

The conserved kinase UNC-51 acts with VAB-8 and UNC-14 to regulate axon outgrowth in C. elegans. Development (2004) 0.99

A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis. Proc Natl Acad Sci U S A (2011) 0.99

Identification of transcriptional regulatory elements in chemosensory receptor genes by probabilistic segmentation. Curr Biol (2005) 0.98

C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development. Development (2009) 0.96

Control of neuronal subtype identity by the C. elegans ARID protein CFI-1. Genes Dev (2002) 0.94

MultiFocus Polarization Microscope (MF-PolScope) for 3D polarization imaging of up to 25 focal planes simultaneously. Opt Express (2015) 0.94

Wnt signaling in neural circuit development. J Neurosci (2005) 0.93

The role of C. elegans Ena/VASP homolog UNC-34 in neuronal polarity and motility. Dev Biol (2010) 0.93

Caenorhabditis elegans flamingo cadherin fmi-1 regulates GABAergic neuronal development. J Neurosci (2012) 0.93

Semaphorin and Eph receptor signaling guide a series of cell movements for ventral enclosure in C. elegans. Curr Biol (2011) 0.92

CDK-5 regulates the abundance of GLR-1 glutamate receptors in the ventral cord of Caenorhabditis elegans. Mol Biol Cell (2007) 0.92

The homeodomain protein hmbx-1 maintains asymmetric gene expression in adult C. elegans olfactory neurons. Genes Dev (2010) 0.91

The Arf GAP CNT-2 regulates the apoptotic fate in C. elegans asymmetric neuroblast divisions. Curr Biol (2011) 0.91