Published in J Cell Sci on March 14, 2006
An expanded biological repertoire for Ins(3,4,5,6)P4 through its modulation of ClC-3 function. Curr Biol (2008) 1.62
The Arabidopsis ATP-binding cassette protein AtMRP5/AtABCC5 is a high affinity inositol hexakisphosphate transporter involved in guard cell signaling and phytate storage. J Biol Chem (2009) 1.22
Integration of inositol phosphate signaling pathways via human ITPK1. J Biol Chem (2007) 1.01
Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain. Biochem J (2011) 0.92
DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways. Am J Respir Cell Mol Biol (2014) 0.91
Molecular basis for the integration of inositol phosphate signaling pathways via human ITPK1. Adv Enzyme Regul (2009) 0.86
Control of TMEM16A by INO-4995 and other inositolphosphates. Br J Pharmacol (2013) 0.80
Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics. Immun Inflamm Dis (2014) 0.75
Transmembrane protein 16A (TMEM16A) is a Ca2+-regulated Cl- secretory channel in mouse airways. J Biol Chem (2009) 2.59
Regulation of the epithelial sodium channel by serine proteases in human airways. J Biol Chem (2001) 2.22
CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium. PLoS Biol (2009) 2.10
In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis. J Biol Chem (2002) 2.02
Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase. Curr Biol (2002) 1.69
An expanded biological repertoire for Ins(3,4,5,6)P4 through its modulation of ClC-3 function. Curr Biol (2008) 1.62
Characterization of the oligomeric structure of the Ca(2+)-activated Cl- channel Ano1/TMEM16A. J Biol Chem (2010) 1.58
PPIP5K1 modulates ligand competition between diphosphoinositol polyphosphates and PtdIns(3,4,5)P3 for polyphosphoinositide-binding domains. Biochem J (2013) 1.55
Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress. J Biol Chem (2007) 1.52
Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases. J Biol Chem (2008) 1.44
Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances. J Gen Physiol (2002) 1.41
An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase. J Biol Chem (2002) 1.37
Structural basis for an inositol pyrophosphate kinase surmounting phosphate crowding. Nat Chem Biol (2011) 1.33
Cystic fibrosis airway epithelial Ca2+ i signaling: the mechanism for the larger agonist-mediated Ca2+ i signals in human cystic fibrosis airway epithelia. J Biol Chem (2005) 1.21
Signaling by higher inositol polyphosphates. Synthesis of bisdiphosphoinositol tetrakisphosphate ("InsP8") is selectively activated by hyperosmotic stress. J Biol Chem (2004) 1.13
SERCA pump inhibitors do not correct biosynthetic arrest of deltaF508 CFTR in cystic fibrosis. Am J Respir Cell Mol Biol (2005) 1.08
BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization. Cell Res (2010) 1.08
Dephosphorylation of 2,3-bisphosphoglycerate by MIPP expands the regulatory capacity of the Rapoport-Luebering glycolytic shunt. Proc Natl Acad Sci U S A (2008) 1.07
Integration of inositol phosphate signaling pathways via human ITPK1. J Biol Chem (2007) 1.01
Cellular energetic status supervises the synthesis of bis-diphosphoinositol tetrakisphosphate independently of AMP-activated protein kinase. Mol Pharmacol (2008) 0.98
Intracellular localization of human Ins(1,3,4,5,6)P5 2-kinase. Biochem J (2007) 0.95
scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications. Chembiochem (2006) 0.93
Inositol 3,4,5,6-tetrakisphosphate inhibits insulin granule acidification and fusogenic potential. J Biol Chem (2002) 0.92
First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase. Chem Commun (Camb) (2012) 0.92
Receptor-dependent compartmentalization of PPIP5K1, a kinase with a cryptic polyphosphoinositide binding domain. Biochem J (2011) 0.92
Signal transduction during environmental stress: InsP8 operates within highly restricted contexts. Cell Signal (2005) 0.92
Synthesis of densely phosphorylated bis-1,5-diphospho-myo-inositol tetrakisphosphate and its enantiomer by bidirectional P-anhydride formation. Angew Chem Int Ed Engl (2014) 0.90
The calcium-dependent chloride conductance mediator pCLCA1. Am J Physiol Cell Physiol (2002) 0.89
Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs. FEBS Lett (2013) 0.89
The nucleolus exhibits an osmotically regulated gatekeeping activity that controls the spatial dynamics and functions of nucleolin. J Biol Chem (2008) 0.88
pCLCA1 becomes a cAMP-dependent chloride conductance mediator in Caco-2 cells. Biochem Biophys Res Commun (2002) 0.88
Avian multiple inositol polyphosphate phosphatase is an active phytase that can be engineered to help ameliorate the planet's "phosphate crisis". J Biotechnol (2006) 0.86
pCLCA1 lacks inherent chloride channel activity in an epithelial colon carcinoma cell line. Am J Physiol Gastrointest Liver Physiol (2004) 0.84
The Ins(1,3,4)P3 5/6-kinase/Ins(3,4,5,6)P4 1-kinase is not a protein kinase. Biochem J (2005) 0.84
Physiological levels of PTEN control the size of the cellular Ins(1,3,4,5,6)P(5) pool. Cell Signal (2005) 0.83
Functional regulation of ClC-3 in the migration of vascular smooth muscle cells. Hypertension (2012) 0.83
Cytosolic multiple inositol polyphosphate phosphatase in the regulation of cytoplasmic free Ca2+ concentration. J Biol Chem (2003) 0.82
Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases. Biochem J (2003) 0.81
On the contribution of stereochemistry to human ITPK1 specificity: Ins(1,4,5,6)P4 is not a physiologic substrate. FEBS Lett (2005) 0.81
A non-catalytic role for inositol 1,3,4,5,6-pentakisphosphate 2-kinase in the synthesis of ribosomal RNA. J Cell Sci (2012) 0.80
Multicenter intestinal current measurements in rectal biopsies from CF and non-CF subjects to monitor CFTR function. PLoS One (2013) 0.79
Metabolic and signaling properties of an Itpk gene family in Glycine max. FEBS Lett (2008) 0.78
The importance to chondrocyte differentiation of changes in expression of the multiple inositol polyphosphate phosphatase. Exp Cell Res (2003) 0.78
Pathogenicity of Salmonella: SopE-mediated membrane ruffling is independent of inositol phosphate signals. FEBS Lett (2006) 0.77
Activation of PLC by an endogenous cytokine (GBP) in Drosophila S3 cells and its application as a model for studying inositol phosphate signalling through ITPK1. Biochem J (2012) 0.75
Synthetic tools for studying the chemical biology of InsP8. Chem Commun (Camb) (2015) 0.75
Retraction: A High-Throughput Screening-Compatible Strategy for the Identification of Inositol Pyrophosphate Kinase Inhibitors. PLoS One (2017) 0.75