Published in J Biol Chem on March 21, 2006
Bile acid transporters. J Lipid Res (2009) 2.31
Tumor necrosis factor and interleukin 1 decrease RXRalpha, PPARalpha, PPARgamma, LXRalpha, and the coactivators SRC-1, PGC-1alpha, and PGC-1beta in liver cells. Metabolism (2007) 1.60
NSAID sulindac and its analog bind RXRalpha and inhibit RXRalpha-dependent AKT signaling. Cancer Cell (2010) 1.22
Transcriptome sequencing, microarray, and proteomic analyses reveal cellular and metabolic impact of hepatitis C virus infection in vitro. Hepatology (2010) 1.17
Retinoid X receptor alpha controls innate inflammatory responses through the up-regulation of chemokine expression. Proc Natl Acad Sci U S A (2010) 1.13
Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output. Hepatology (2011) 1.11
Sterol regulation of metabolism, homeostasis, and development. Annu Rev Biochem (2011) 1.08
The role of inflammation in cholestasis: clinical and basic aspects. Semin Liver Dis (2010) 1.07
Pathogenesis of alcoholic liver disease: the role of nuclear receptors. Exp Biol Med (Maywood) (2010) 1.00
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model. BMC Bioinformatics (2007) 0.96
Implication of inflammatory macrophages, nuclear receptors, and interferon regulatory factors in increased virulence of pandemic 2009 H1N1 influenza A virus after host adaptation. J Virol (2012) 0.96
Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha. J Hepatol (2009) 0.93
Differential role of Toll-interleukin 1 receptor domain-containing adaptor protein in Toll-like receptor 2-mediated regulation of gene expression of hepatic cytokines and drug-metabolizing enzymes. Drug Metab Dispos (2011) 0.92
Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters. Life Sci (2011) 0.90
Differential pulmonary transcriptomic profiles in murine lungs infected with low and highly virulent influenza H3N2 viruses reveal dysregulation of TREM1 signaling, cytokines, and chemokines. Funct Integr Genomics (2011) 0.89
Constitutive activation of the mitogen-activated protein kinase pathway impairs vitamin D signaling in human prostate epithelial cells. J Cell Physiol (2010) 0.89
Regulation of gene expression of hepatic drug metabolizing enzymes and transporters by the Toll-like receptor 2 ligand, lipoteichoic acid. Arch Biochem Biophys (2008) 0.89
Targeting truncated retinoid X receptor-α by CF31 induces TNF-α-dependent apoptosis. Cancer Res (2012) 0.88
Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver. J Hepatol (2006) 0.88
Phosphorylation of serine 271 on 5-lipoxygenase and its role in nuclear export. J Biol Chem (2008) 0.85
Transcription networks responsible for early regulation of Salmonella-induced inflammation in the jejunum of pigs. J Inflamm (Lond) (2013) 0.85
Peroxisome proliferator-activated receptor and retinoic x receptor in alcoholic liver disease. PPAR Res (2009) 0.85
Regulation of the nongenomic actions of retinoid X receptor-α by targeting the coregulator-binding sites. Acta Pharmacol Sin (2014) 0.83
Extrahepatic cancer suppresses nuclear receptor-regulated drug metabolism. Clin Cancer Res (2011) 0.83
Gene-specific alterations of hepatic gene expression by ligand activation or hepatocyte-selective inhibition of retinoid X receptor-α signalling during inflammation. Liver Int (2011) 0.82
Molecular and macromolecular alterations of recombinant adenoviral vectors do not resolve changes in hepatic drug metabolism during infection. Virol J (2008) 0.82
Nuclear receptors: mediators and modifiers of inflammation-induced cholestasis. Front Biosci (Landmark Ed) (2009) 0.81
Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells. Mol Pharmacol (2013) 0.81
Systemic and local release of inflammatory cytokines regulates hepatobiliary excretion of 99mTc-mebrofenin. Nucl Med Commun (2008) 0.81
Sulindac-derived RXRα modulators inhibit cancer cell growth by binding to a novel site. Chem Biol (2014) 0.78
Activation of liver X receptor/retinoid X receptor pathway ameliorates liver disease in Atp7B(-/-) (Wilson disease) mice. Hepatology (2016) 0.78
NSC-640358 acts as RXRα ligand to promote TNFα-mediated apoptosis of cancer cell. Protein Cell (2015) 0.75
Cocaine induces nuclear export and degradation of neuronal retinoid X receptor-γ via a TNF-α/JNK- mediated mechanism. J Neuroimmune Pharmacol (2015) 0.75
Targeting truncated RXRα for cancer therapy. Acta Biochim Biophys Sin (Shanghai) (2015) 0.75
Selective Inhibitor of Nuclear Export (SINE) Compounds Alter New World Alphavirus Capsid Localization and Reduce Viral Replication in Mammalian Cells. PLoS Negl Trop Dis (2016) 0.75
A pre-neoplastic epigenetic field defect in HCV-infected liver at transcription factor binding sites and polycomb targets. Oncogene (2016) 0.75
Post-translational modifications of lipid-activated nuclear receptors: Focus on metabolism. Endocrinology (2016) 0.75
Redundant pathways for negative feedback regulation of bile acid production. Dev Cell (2002) 3.51
Actin restricts FcepsilonRI diffusion and facilitates antigen-induced receptor immobilization. Nat Cell Biol (2008) 3.15
Mucin is produced by clara cells in the proximal airways of antigen-challenged mice. Am J Respir Cell Mol Biol (2004) 2.50
Pattern of diagnostic evaluation for the causes of pediatric acute liver failure: an opportunity for quality improvement. J Pediatr (2009) 2.46
Disrupted junctional membrane complexes and hyperactive ryanodine receptors after acute junctophilin knockdown in mice. Circulation (2011) 2.21
Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia. Circulation (2009) 2.19
Mediation of electronegative low-density lipoprotein signaling by LOX-1: a possible mechanism of endothelial apoptosis. Circ Res (2009) 1.83
Extrahepatic anomalies in infants with biliary atresia: results of a large prospective North American multicenter study. Hepatology (2013) 1.80
Phytosterols promote liver injury and Kupffer cell activation in parenteral nutrition-associated liver disease. Sci Transl Med (2013) 1.77
Patients with biliary atresia have elevated direct/conjugated bilirubin levels shortly after birth. Pediatrics (2011) 1.75
A pure population of lung alveolar epithelial type II cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2007) 1.74
The natural history of hepatitis C virus in pediatric liver transplant recipients. Liver Transpl (2006) 1.61
Combined lung and liver transplantation: the United States experience. Transplantation (2005) 1.58
Epidermal growth factor-mediated activation of the ETS domain transcription factor Elk-1 requires nuclear calcium. J Biol Chem (2002) 1.53
Neonatal hemochromatosis: radiographical and histological signs. Liver Transpl (2005) 1.50
Analysis of recent pediatric orthotopic liver transplantation outcomes indicates that allograft type is no longer a predictor of survivals. Liver Transpl (2008) 1.46
FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. J Clin Invest (2016) 1.45
Role of alpha4 integrin and VCAM-1 in CD18-independent neutrophil migration across mouse cardiac endothelium. Circ Res (2002) 1.42
Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR. Pediatr Res (2007) 1.38
Extracellular ATP activates c-jun N-terminal kinase signaling and cell cycle progression in hepatocytes. Hepatology (2004) 1.35
Two waves of neutrophil emigration in response to corneal epithelial abrasion: distinct adhesion molecule requirements. Invest Ophthalmol Vis Sci (2006) 1.35
Microvascular thrombosis models in venules and arterioles in vivo. Microcirculation (2005) 1.34
Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation. Nucl Recept (2004) 1.30
gamma delta T cells are necessary for platelet and neutrophil accumulation in limbal vessels and efficient epithelial repair after corneal abrasion. Am J Pathol (2007) 1.29
Endotoxin enhances microvascular thrombosis in mouse cremaster venules via a TLR4-dependent, neutrophil-independent mechanism. Am J Physiol Heart Circ Physiol (2005) 1.27
CCL20, γδ T cells, and IL-22 in corneal epithelial healing. FASEB J (2011) 1.26
Mouse cremaster venules are predisposed to light/dye-induced thrombosis independent of wall shear rate, CD18, ICAM-1, or P-selectin. Microcirculation (2004) 1.23
Regulation of inducible nitric oxide synthase by aggresome formation. Proc Natl Acad Sci U S A (2005) 1.23
Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer. Oncogene (2004) 1.21
IL-17 and VEGF are necessary for efficient corneal nerve regeneration. Am J Pathol (2011) 1.21
Long-term medical management of the pediatric patient after liver transplantation: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation. Liver Transpl (2013) 1.19
Treatment of children with chronic hepatitis B virus infection in the United States: patient selection and therapeutic options. Hepatology (2010) 1.19
Platelet response to corneal abrasion is necessary for acute inflammation and efficient re-epithelialization. Invest Ophthalmol Vis Sci (2006) 1.17
Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent. J Biol Chem (2002) 1.16
Split-liver transplantation using the left lateral segment: a collaborative sharing experience between two distant centers. Am J Transplant (2005) 1.09
The role of inflammation in cholestasis: clinical and basic aspects. Semin Liver Dis (2010) 1.07
Neutrophil interactions with keratocytes during corneal epithelial wound healing: a role for CD18 integrins. Invest Ophthalmol Vis Sci (2007) 1.07
Evaluation and management of patients with propionic acidemia undergoing liver transplantation: a comprehensive review. Pediatr Transplant (2006) 1.06
Kupffer cell depletion with liposomal clodronate prevents suppression of Ntcp expression in endotoxin-treated rats. J Hepatol (2005) 1.05
Intrahepatic cholestasis: summary of an American Association for the Study of Liver Diseases single-topic conference. Hepatology (2005) 1.04
Lymphocyte function-associated antigen-1-dependent inhibition of corneal wound healing. Am J Pathol (2006) 1.03
Portal hypertension in children and young adults with biliary atresia. J Pediatr Gastroenterol Nutr (2012) 1.01
Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia. Pediatrics (2012) 1.00
Risk stratification of adult patients undergoing orthotopic liver transplantation for fulminant hepatic failure. Transplantation (2006) 1.00
Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis. Hepatology (2010) 0.99
Evidence for the involvement of myoendothelial gap junctions in EDHF-mediated relaxation in the rat middle cerebral artery. Am J Physiol Heart Circ Physiol (2006) 0.98
ICAM-1 is necessary for epithelial recruitment of gammadelta T cells and efficient corneal wound healing. Am J Pathol (2009) 0.98
Liver tumors: pediatric population. Liver Transpl (2008) 0.98
ATP release after partial hepatectomy regulates liver regeneration in the rat. J Hepatol (2009) 0.98
Do therapeutic bile acids hit the sweet spot of glucose metabolism in NAFLD? Gastroenterology (2013) 0.97
Treatment of neonatal hemochromatosis with exchange transfusion and intravenous immunoglobulin. J Pediatr (2009) 0.97
Endothelial nitric oxide synthase is a key mediator of hepatocyte proliferation in response to partial hepatectomy in mice. Hepatology (2011) 0.96
Androgens promote prostate cancer cell growth through induction of autophagy. Mol Endocrinol (2012) 0.95
Recommendations for screening, monitoring, and referral of pediatric chronic hepatitis B. Pediatrics (2009) 0.95
The giant danio (D. aequipinnatus) as a model of cardiac remodeling and regeneration. Anat Rec (Hoboken) (2011) 0.94
Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride. J Hepatol (2002) 0.94
Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha. J Hepatol (2009) 0.93
Platelets enhance neutrophil transendothelial migration via P-selectin glycoprotein ligand-1. Am J Physiol Heart Circ Physiol (2010) 0.93
Pathways of corneal and ocular surface inflammation: a perspective from the cullen symposium. Ocul Surf (2005) 0.92
Regulation of hepatic drug-metabolizing enzyme genes by Toll-like receptor 4 signaling is independent of Toll-interleukin 1 receptor domain-containing adaptor protein. Drug Metab Dispos (2007) 0.92
Intestinal failure-associated liver disease: management and treatment strategies past, present, and future. Semin Liver Dis (2007) 0.91
Guideline for the Evaluation of Cholestatic Jaundice in Infants: Joint Recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr (2017) 0.91
Oncostatin M differentially regulates CXC chemokines in mouse cardiac fibroblasts. Am J Physiol Cell Physiol (2006) 0.91
ICAM-1 mediates surface contact between neutrophils and keratocytes following corneal epithelial abrasion in the mouse. Exp Eye Res (2010) 0.90
Drug disposition in pathophysiological conditions. Curr Drug Metab (2012) 0.90
Role of c-Jun N-terminal kinase (JNK) in regulating tumor necrosis factor-alpha (TNF-alpha) mediated increase of acetaminophen (APAP) and chlorpromazine (CPZ) toxicity in murine hepatocytes. J Toxicol Sci (2010) 0.90
Relationship of lipoprotein-associated phospholipase A2 and oxidized low density lipoprotein in carotid atherosclerosis. J Lipid Res (2009) 0.89
Language and motor skills are impaired in infants with biliary atresia before transplantation. J Pediatr (2010) 0.89
In vivo dynamics of carbapenem-resistant Pseudomonas aeruginosa selection after suboptimal dosing. Diagn Microbiol Infect Dis (2009) 0.88
Assessment of postnatal corneal development in the C57BL/6 mouse using spectral domain optical coherence tomography and microwave-assisted histology. Exp Eye Res (2011) 0.88
Rosiglitazone attenuates suppression of RXRalpha-dependent gene expression in inflamed liver. J Hepatol (2006) 0.88
NK cells modulate the inflammatory response to corneal epithelial abrasion and thereby support wound healing. Am J Pathol (2012) 0.87
Cardiac structural and functional alterations in infants and children with biliary atresia, listed for liver transplantation. Gastroenterology (2011) 0.87
Liver transplantation for severe hepatic graft-versus-host disease: an analysis of aggregate survival data. Liver Transpl (2005) 0.87
Progressive familial intrahepatic cholestasis type 3: overlapping presentation with Wilson disease. Clin Pediatr (Phila) (2012) 0.86
Orthotopic liver transplantation for biliary atresia: the U.S. experience. Liver Transpl (2005) 0.86
Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma. J Clin Invest (2015) 0.86
Evaluation of asymmetric liposomal nanoparticles for encapsulation of polynucleotides. Langmuir (2008) 0.86
Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat. J Hepatol (2003) 0.85
Treatment of acute tacrolimus whole-blood elevation with phenobarbital in the pediatric liver transplant recipient. Pediatr Transplant (2005) 0.84
Morphologic findings in progressive familial intrahepatic cholestasis 2 (PFIC2): correlation with genetic and immunohistochemical studies. Am J Surg Pathol (2011) 0.84
The pediatric end-stage liver disease (PELD) model as a predictor of survival benefit and posttransplant survival in pediatric liver transplant recipients. Liver Transpl (2006) 0.84
Role of constitutive androstane receptor in Toll-like receptor-mediated regulation of gene expression of hepatic drug-metabolizing enzymes and transporters. Drug Metab Dispos (2013) 0.84
Hindlimb unloading depresses corneal epithelial wound healing in mice. J Appl Physiol (1985) (2004) 0.84
Hydroxyethyl starch inhibits neutrophil adhesion and transendothelial migration. Shock (2005) 0.83
Extra domain A and type III connecting segment of fibronectin in assembly and cleavage. Biochem Biophys Res Commun (2005) 0.83
Functional nanocomposites prepared by self-assembly and polymerization of diacetylene surfactants and silicic acid. J Am Chem Soc (2003) 0.83
Intravenous Cidofovir therapy for disseminated adenovirus in a pediatric liver transplant recipient. Transplantation (2002) 0.82
Cardiac myocyte diversity and a fibroblast network in the junctional region of the zebrafish heart revealed by transmission and serial block-face scanning electron microscopy. PLoS One (2013) 0.82
Sexually dimorphic genome-wide binding of retinoid X receptor alpha (RXRα) determines male-female differences in the expression of hepatic lipid processing genes in mice. PLoS One (2013) 0.82
Gene-specific alterations of hepatic gene expression by ligand activation or hepatocyte-selective inhibition of retinoid X receptor-α signalling during inflammation. Liver Int (2011) 0.82
Sustained elevations in NEFA induce cyclooxygenase-2 activity and potentiate THP-1 macrophage foam cell formation. Atherosclerosis (2006) 0.82
Asymptomatic small bowel intussusception associated with post-transplant lymphoproliferative disease. Pediatr Transplant (2004) 0.81
Inflammatory mediators increase SUMOylation of retinoid X receptor α in a c-Jun N-terminal kinase-dependent manner in human hepatocellular carcinoma cells. Mol Pharmacol (2013) 0.81