Published in Circ J on April 01, 2006
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Pirfenidone is renoprotective in diabetic kidney disease. J Am Soc Nephrol (2009) 1.29
Cardiovascular and autonomic phenotype of db/db diabetic mice. Exp Physiol (2009) 1.23
Diabetes and cardiovascular autonomic dysfunction: application of animal models. Auton Neurosci (2008) 0.90
Decline in cellular function of aged mouse c-kit(+) cardiac progenitor cells. J Physiol (2017) 0.88
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Inhibition of NF-κB-induced inflammatory responses by angiotensin II antagonists in aged rat kidney. Exp Gerontol (2011) 0.80
Valsartan ameliorates ageing-induced aorta degeneration via angiotensin II type 1 receptor-mediated ERK activity. J Cell Mol Med (2014) 0.75
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell (2002) 4.35
Rivaroxaban vs. warfarin in Japanese patients with atrial fibrillation – the J-ROCKET AF study –. Circ J (2012) 3.70
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload. Circulation (2004) 3.35
Phosphoinositide 3-kinase(p110alpha) plays a critical role for the induction of physiological, but not pathological, cardiac hypertrophy. Proc Natl Acad Sci U S A (2003) 2.90
Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke Trial. Stroke (2005) 2.56
SCREAM/ICE1 and SCREAM2 specify three cell-state transitional steps leading to arabidopsis stomatal differentiation. Plant Cell (2008) 2.33
The insulin-like growth factor 1 receptor induces physiological heart growth via the phosphoinositide 3-kinase(p110alpha) pathway. J Biol Chem (2003) 2.28
High risks of all-cause and cardiovascular deaths in apparently healthy middle-aged people with preserved glomerular filtration rate and albuminuria: A prospective cohort study. Int J Cardiol (2013) 2.06
Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma. Blood (2010) 2.00
Evaluation of the impact of atrial fibrillation on rehospitalization events in heart failure patients in recent years. J Cardiol (2012) 2.00
Deficiency of endothelial nitric-oxide synthase confers susceptibility to diabetic nephropathy in nephropathy-resistant inbred mice. Am J Pathol (2007) 1.95
Protective effects of exercise and phosphoinositide 3-kinase(p110alpha) signaling in dilated and hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A (2007) 1.82
A national survey on myocarditis associated with the 2009 influenza A (H1N1) pandemic in Japan. Circ J (2010) 1.79
Negative interactions in close relationships across the life span. J Gerontol B Psychol Sci Soc Sci (2003) 1.74
Lipopolysaccharide-induced myocardial protection against ischaemia/reperfusion injury is mediated through a PI3K/Akt-dependent mechanism. Cardiovasc Res (2008) 1.70
Influence of the great East Japan earthquake and tsunami 2011 on occurrence of cerebrovascular diseases in Iwate, Japan. Stroke (2013) 1.70
Analysis of liver metabolism in a rat model of heart failure. Int J Cardiol (2011) 1.68
RET/PTC rearrangements preferentially occurred in papillary thyroid cancer among atomic bomb survivors exposed to high radiation dose. Cancer Res (2008) 1.67
Satb1 and Satb2 regulate embryonic stem cell differentiation and Nanog expression. Genes Dev (2009) 1.67
Serum levels of interleukin-10 on admission as a prognostic predictor of human fulminant myocarditis. J Am Coll Cardiol (2004) 1.57
Inheritance of polyalanine expansion mutation of PHOX2B in congenital central hypoventilation syndrome. J Hum Genet (2012) 1.52
Prognostic utility of B-type natriuretic peptide assessment in stable low-risk outpatients with nonischemic cardiomyopathy after decompensated heart failure. J Am Coll Cardiol (2008) 1.52
Plasma B-type natriuretic peptide level and cardiovascular events in chronic kidney disease in a community-based population. Circ J (2010) 1.47
Hemodialysis is an independent predictor of coronary in-stent restenosis after paclitaxel eluting stent implantation. Intern Med (2010) 1.46
Angiotensin II upregulates acyl-CoA:cholesterol acyltransferase-1 via the angiotensin II Type 1 receptor in human monocyte-macrophages. Hypertens Res (2008) 1.46
Intensively lowering both low-density lipoprotein cholesterol and blood pressure does not reduce cardiovascular risk in Japanese coronary artery disease patients. Circ J (2011) 1.45
Two cases of Brugada syndrome associated with spontaneous clinical episodes of coronary vasospasm. Intern Med (2006) 1.45
Angiotensin II-mediated up-regulation of connective tissue growth factor promotes atrial tissue fibrosis in the canine atrial fibrillation model. Europace (2012) 1.45
Deletion of ribosomal S6 kinases does not attenuate pathological, physiological, or insulin-like growth factor 1 receptor-phosphoinositide 3-kinase-induced cardiac hypertrophy. Mol Cell Biol (2004) 1.43
A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy. Cell Metab (2007) 1.42
Low-grade albuminuria and incidence of cardiovascular disease and all-cause mortality in nondiabetic and normotensive individuals. J Hypertens (2016) 1.42
Effect of hypothermia therapy after outpatient cardiac arrest due to ventricular fibrillation. Circ J (2009) 1.41
Phosphoglucomutase activity as a novel biomarker in patients with acute myocardial infarction. Circ J (2012) 1.40
Cardiomyocyte-derived mitochondrial superoxide causes myocardial electrical remodeling by downregulating potassium channels and related molecules. Circ J (2014) 1.39
Efficacy and safety of tolvaptan in heart failure patients with volume overload despite the standard treatment with conventional diuretics: a phase III, randomized, double-blind, placebo-controlled study (QUEST study). Cardiovasc Drugs Ther (2011) 1.37
Analysis of metabolic remodeling in compensated left ventricular hypertrophy and heart failure. Circ Heart Fail (2010) 1.35
Sympathetic nervous activity and myocardial damage immediately after subarachnoid hemorrhage in a unique animal model. Stroke (2002) 1.35
Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes. J Am Soc Nephrol (2006) 1.34
MURC, a muscle-restricted coiled-coil protein that modulates the Rho/ROCK pathway, induces cardiac dysfunction and conduction disturbance. Mol Cell Biol (2008) 1.33
Improved RT-PCR amplification for molecular analyses with long-term preserved formalin-fixed, paraffin-embedded tissue specimens. J Histochem Cytochem (2006) 1.29
Prognostic significance of increased serum bilirubin levels coincident with cardiac decompensation in chronic heart failure. Circ J (2008) 1.27
Attachment and close relationships across the life span. Attach Hum Dev (2004) 1.27
A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development. Mol Cell Biol (2003) 1.27
PI3K(p110 alpha) protects against myocardial infarction-induced heart failure: identification of PI3K-regulated miRNA and mRNA. Arterioscler Thromb Vasc Biol (2010) 1.24
Reduction of renal superoxide dismutase in progressive diabetic nephropathy. J Am Soc Nephrol (2009) 1.23
Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo. Free Radic Biol Med (2005) 1.17
Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice. Circulation (2009) 1.16
CRP levels are elevated in smokers but unrelated to the number of cigarettes and are decreased by long-term smoking cessation in male smokers. Prev Med (2005) 1.11
Spectra of functional gastrointestinal disorders diagnosed by Rome III integrative questionnaire in a Japanese outpatient office and the impact of overlapping. J Gastroenterol Hepatol (2010) 1.09
The tyrosine phosphatase CD148 interacts with the p85 regulatory subunit of phosphoinositide 3-kinase. Biochem J (2008) 1.08
Reduced phosphoinositide 3-kinase (p110alpha) activation increases the susceptibility to atrial fibrillation. Am J Pathol (2009) 1.07
Elevated circulating levels of an incretin hormone, glucagon-like peptide-1, are associated with metabolic components in high-risk patients with cardiovascular disease. Cardiovasc Diabetol (2010) 1.07
Circulating levels of interleukin 18 reflect etiologies of heart failure: Th1/Th2 cytokine imbalance exaggerates the pathophysiology of advanced heart failure. J Card Fail (2002) 1.07
Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. Cancer Res (2002) 1.05
Oxidized high-density lipoprotein as a risk factor for cardiovascular events in prevalent hemodialysis patients. Atherosclerosis (2011) 1.05
Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice. J Mol Cell Cardiol (2011) 1.03
Serum C-reactive protein levels can be used to predict future ischemic stroke and mortality in Japanese men from the general population. Atherosclerosis (2008) 1.03
Change of oxygen pressure in glioblastoma tissue under various conditions. J Neurooncol (2002) 1.02
E7050: a dual c-Met and VEGFR-2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models. Cancer Sci (2009) 1.02
A monoclonal antibody against CD148, a receptor-like tyrosine phosphatase, inhibits endothelial-cell growth and angiogenesis. Blood (2006) 1.01
Disruption of inducible nitric oxide synthase improves beta-adrenergic inotropic responsiveness but not the survival of mice with cytokine-induced cardiomyopathy. Circ Res (2002) 0.99
Predictive value of plasma B-type natriuretic peptide for ischemic stroke: a community-based longitudinal study. Atherosclerosis (2009) 0.99
Reproducibility and validity of a food frequency questionnaire among Vietnamese in Ho Chi Minh City. J Am Coll Nutr (2005) 0.98
Microarray analysis of cellular thermotolerance. Lasers Surg Med (2010) 0.98
Effects of ezetimibe add-on therapy for high-risk patients with dyslipidemia. Lipids Health Dis (2009) 0.97
Two-step colocalization of MORC3 with PML nuclear bodies. J Cell Sci (2010) 0.97
Sivelestat sodium hydrate improves septic acute lung injury by reducing alveolar dysfunction. Res Commun Mol Pathol Pharmacol (2006) 0.96
Primary cardiac osteosarcoma in a young man with severe congestive heart failure. Intern Med (2007) 0.96
Rearranged anaplastic lymphoma kinase (ALK) gene in adult-onset papillary thyroid cancer amongst atomic bomb survivors. Thyroid (2012) 0.96
Phase III clinical pharmacology study of tolvaptan. Cardiovasc Drugs Ther (2011) 0.96
Cardiovascular risk factors in the Japanese northeastern rural population. Int J Cardiol (2008) 0.95
MRI is useful for diagnosis of H1N1 fulminant myocarditis. Circ J (2010) 0.94
Clinical significance of corticosteroid therapy for eosinophilic myocarditis. Int Heart J (2011) 0.94
The anti-atherosclerotic effects of lipid lowering with atorvastatin in patients with hypercholesterolemia. J Atheroscler Thromb (2006) 0.93
Modulation of renal superoxide dismutase by telmisartan therapy in C57BL/6-Ins2(Akita) diabetic mice. Hypertens Res (2011) 0.93
Cytotoxic effects of histone deacetylase inhibitor FK228 (depsipeptide, formally named FR901228) in combination with conventional anti-leukemia/lymphoma agents against human leukemia/lymphoma cell lines. Invest New Drugs (2007) 0.93
Clinical significance of heart rate during acute decompensated heart failure to predict left ventricular reverse remodeling and prognosis in response to therapies in nonischemic dilated cardiomyopathy. Heart Vessels (2013) 0.93
Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion. Crit Care Med (2003) 0.92
Retropharyngeal abscess due to methicillin-resistant Staphylococcus aureus in a case of acute myeloid leukemia. Intern Med (2005) 0.92
Prehypertension subtype with elevated C-reactive protein: risk of ischemic stroke in a general Japanese population. Am J Hypertens (2010) 0.91
Vasospasms of the radial artery after the transradial approach for coronary angiography and angioplasty. Jpn Heart J (2004) 0.91
Improvement of quality of life with nocturnal oxygen therapy in heart failure patients with central sleep apnea. Circ J (2009) 0.91
Role of HSP70 in cellular thermotolerance. Lasers Surg Med (2008) 0.91
Resistin, an adipocytokine, offers protection against acute myocardial infarction. J Mol Cell Cardiol (2007) 0.91
Lack of cholecystokinin-A receptor enhanced gallstone formation: a study in CCK-A receptor gene knockout mice. Dig Dis Sci (2003) 0.91
Age-dependent changes in cell proliferation and cell death in the periodontal tissue and the submandibular gland in mice: a comparison with other tissues and organs. J Mol Histol (2007) 0.90
Genome-wide expression analysis of genes affected by amino acid sensor Ssy1p in Saccharomyces cerevisiae. Curr Genet (2002) 0.90
Impact of fibroblast growth factor 23 on lipids and atherosclerosis in hemodialysis patients. Ther Apher Dial (2010) 0.90
Resveratrol ameliorates experimental autoimmune myocarditis. Circ J (2007) 0.90