PubRank

Laurel Thomas

Author PubWeight™ 20.19‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. EMBO J 2005 3.10
2 HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway. Cell 2002 2.27
3 The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4. J Virol 2003 1.52
4 Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production. J Virol 2003 1.31
5 HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I. Cell Host Microbe 2007 1.26
6 The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic. EMBO J 2003 1.22
7 HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. J Biol Chem 2008 1.22
8 Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Mol Cell 2009 1.19
9 An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I. Mol Biol Cell 2012 1.18
10 AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1. EMBO Rep 2003 1.17
11 A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking. EMBO J 2006 1.15
12 Identification of a pH sensor in the furin propeptide that regulates enzyme activation. J Biol Chem 2006 1.14
13 Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Mol Biol Cell 2010 1.10
14 Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2). J Biol Chem 2012 0.95
15 Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology 2013 0.83