PubRank

Gary Thomas

Author PubWeight™ 47.48‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. EMBO J 2005 3.10
2 HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway. Cell 2002 2.27
3 Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. EMBO J 2005 2.12
4 The PHD/LAP-domain protein M153R of myxomavirus is a ubiquitin ligase that induces the rapid internalization and lysosomal destruction of CD4. J Virol 2003 1.52
5 The subcellular distribution of calnexin is mediated by PACS-2. Mol Biol Cell 2008 1.51
6 Oxidative protein folding in the endoplasmic reticulum: tight links to the mitochondria-associated membrane (MAM). Biochim Biophys Acta 2010 1.50
7 A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in renal cell carcinoma. Sci Transl Med 2011 1.48
8 Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells. Blood 2006 1.43
9 The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation. J Biol Chem 2002 1.41
10 Proprotein convertase furin interacts with and cleaves pro-ADAMTS4 (Aggrecanase-1) in the trans-Golgi network. J Biol Chem 2004 1.33
11 Role of PACS-1 in trafficking of human cytomegalovirus glycoprotein B and virus production. J Virol 2003 1.31
12 Cleavages within the prodomain direct intracellular trafficking and degradation of mature bone morphogenetic protein-4. Mol Biol Cell 2004 1.31
13 HIV-1 Nef assembles a Src family kinase-ZAP-70/Syk-PI3K cascade to downregulate cell-surface MHC-I. Cell Host Microbe 2007 1.26
14 The phosphorylation state of an autoregulatory domain controls PACS-1-directed protein traffic. EMBO J 2003 1.22
15 HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. J Biol Chem 2008 1.22
16 Synthetic small molecule furin inhibitors derived from 2,5-dideoxystreptamine. Proc Natl Acad Sci U S A 2006 1.19
17 Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis. Mol Cell 2009 1.19
18 An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I. Mol Biol Cell 2012 1.18
19 Inhibition of furin-mediated processing results in suppression of astrocytoma cell growth and invasiveness. Clin Cancer Res 2002 1.17
20 AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1. EMBO Rep 2003 1.17
21 A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking. EMBO J 2006 1.15
22 At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis. Biochem J 2009 1.15
23 Identification of a pH sensor in the furin propeptide that regulates enzyme activation. J Biol Chem 2006 1.14
24 Insights from bacterial subtilases into the mechanisms of intramolecular chaperone-mediated activation of furin. Methods Mol Biol 2011 1.10
25 Small molecule inhibition of HIV-1-induced MHC-I down-regulation identifies a temporally regulated switch in Nef action. Mol Biol Cell 2010 1.10
26 Retrieval of human cytomegalovirus glycoprotein B from cell surface is not required for virus envelopment in astrocytoma cells. J Virol 2002 1.07
27 Death by committee: organellar trafficking and communication in apoptosis. Traffic 2009 0.97
28 Using local authority data for action on health inequalities: the Caerphilly Health and Social Needs Study. Br J Gen Pract 2002 0.97
29 Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) protein-induced lysosomal translocation of proapoptotic effectors is mediated by phosphofurin acidic cluster sorting protein-2 (PACS-2). J Biol Chem 2012 0.95
30 PACS-1 mediates phosphorylation-dependent ciliary trafficking of the cyclic-nucleotide-gated channel in olfactory sensory neurons. J Neurosci 2009 0.95
31 Small molecule inhibitors of the HIV-1 virulence factor, Nef. Drug Discov Today Technol 2013 0.90
32 Sustained phosphorylation of Bid is a marker for resistance to Fas-induced apoptosis during chronic liver diseases. Gastroenterology 2006 0.88
33 An acidic cluster of the cytoplasmic tail of the RD114 virus glycoprotein controls assembly of retroviral envelopes. Traffic 2007 0.88
34 Profibrillin-1 maturation by human dermal fibroblasts: proteolytic processing and molecular chaperones. J Cell Biochem 2003 0.87
35 Modeling the sound levels produced by bubble release of individual herring. J Acoust Soc Am 2008 0.87
36 Propeptides are sufficient to regulate organelle-specific pH-dependent activation of furin and proprotein convertase 1/3. J Mol Biol 2012 0.87
37 The mechanism by which a propeptide-encoded pH sensor regulates spatiotemporal activation of furin. J Biol Chem 2013 0.86
38 Discovery of a diaminoquinoxaline benzenesulfonamide antagonist of HIV-1 Nef function using a yeast-based phenotypic screen. Retrovirology 2013 0.83
39 A homeostatic switch in PACS-2 links membrane traffic to TRAIL-induced apoptosis. Cell Cycle 2009 0.78
40 A patient with new onset seizures. Herpes encephalitis. J Clin Neurosci 2013 0.75
41 Passive acoustic detection of schools of herring. J Acoust Soc Am 2009 0.75