Published in Cell Regul on September 01, 1991
Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol Cell Biol (1995) 3.02
Fibroblast growth factor 2 internal ribosome entry site (IRES) activity ex vivo and in transgenic mice reveals a stringent tissue-specific regulation. J Cell Biol (2000) 1.78
Translation of CUG- but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells. J Cell Biol (1996) 1.73
A new 34-kilodalton isoform of human fibroblast growth factor 2 is cap dependently synthesized by using a non-AUG start codon and behaves as a survival factor. Mol Cell Biol (1999) 1.61
c-myc Internal ribosome entry site activity is developmentally controlled and subjected to a strong translational repression in adult transgenic mice. Mol Cell Biol (2001) 1.53
A complex role for FGF-2 in self-renewal, survival, and adhesion of human embryonic stem cells. Stem Cells (2009) 1.46
Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors. Mol Biol Cell (2001) 1.20
cis-acting elements involved in the alternative translation initiation process of human basic fibroblast growth factor mRNA. Mol Cell Biol (1992) 1.20
Nuclear trafficking of secreted factors and cell-surface receptors: new pathways to regulate cell proliferation and differentiation, and involvement in cancers. Cell Commun Signal (2006) 1.12
Internal ribosome entry site structural motifs conserved among mammalian fibroblast growth factor 1 alternatively spliced mRNAs. Mol Cell Biol (2004) 1.09
Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells. J Cell Biol (1994) 1.05
FGF2 translationally induced by hypoxia is involved in negative and positive feedback loops with HIF-1alpha. PLoS One (2008) 1.00
High molecular weight FGF2: the biology of a nuclear growth factor. Cell Mol Life Sci (2009) 0.84
Antisense masking reveals contributions of mRNA-rRNA base pairing to translation of Gtx and FGF2 mRNAs. J Biol Chem (2008) 0.81
Endogenous basic fibroblast growth factor isoforms involved in different intracellular protein complexes. Biochem J (1997) 0.79
Inhibition of interleukin-6 promoter activity by the 24 kDa isoform of fibroblast growth factor-2 in HeLa cells. Biochem J (1999) 0.76
Cells retrovirally transfected with fibroblast growth factor-2 isoforms exhibit altered adenylate cyclase activity and G-protein functionality. Biochem J (1996) 0.75
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res (1990) 20.53
Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proc Natl Acad Sci U S A (1988) 9.35
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell (1991) 8.99
Cooperation between oncogenes. Cell (1991) 3.88
An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family. Cell (1987) 3.78
CUG initiation codon used for the synthesis of a cell surface antigen coded by the murine leukemia virus. J Mol Biol (1989) 3.56
High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc Natl Acad Sci U S A (1989) 3.45
The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors. Mol Cell Biol (1988) 3.40
Subcellular fate of the int-2 oncoprotein is determined by choice of initiation codon. Nature (1990) 3.19
Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons. Proc Natl Acad Sci U S A (1989) 3.00
Potential oncogene product related to growth factors. Nature (1987) 2.53
Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor. Mol Cell Biol (1991) 2.47
Fibroblast growth factor. Mol Cell Endocrinol (1986) 2.26
Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. Oncogene (1989) 2.20
Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature (1988) 2.04
Translocation of bFGF to the nucleus is G1 phase cell cycle specific in bovine aortic endothelial cells. EMBO J (1990) 1.85
Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J Cell Physiol (1990) 1.75
Protein and cDNA sequence of a glycine-rich, dimethylarginine-containing region located near the carboxyl-terminal end of nucleolin (C23 and 100 kDa). J Biol Chem (1986) 1.67
Basic fibroblast growth factor in human rhabdomyosarcoma cells: implications for the proliferation and neovascularization of myoblast-derived tumors. Proc Natl Acad Sci U S A (1987) 1.38
Transformation of mouse BALB/c 3T3 cells with human basic fibroblast growth factor cDNA. Mol Cell Biol (1988) 1.13
Addition of growth hormone secretion signal to basic fibroblast growth factor results in cell transformation and secretion of aberrant forms of the protein. Oncogene (1988) 1.11
Transformation by basic fibroblast growth factor requires high levels of expression: comparison with transformation by hst/K-fgf. Oncogene Res (1989) 1.05
An amino-terminally extended and post-translationally modified form of a 25kD basic fibroblast growth factor. Biochem Biophys Res Commun (1989) 0.95
Factors influencing efficiency and reproducibility of polybrene-assisted gene transfer. Somat Cell Mol Genet (1988) 0.95
Nucleolin, the major nucleolar protein of growing eukaryotic cells: an unusual protein structure revealed by the nucleotide sequence. Proc Natl Acad Sci U S A (1987) 3.89
GAR1 is an essential small nucleolar RNP protein required for pre-rRNA processing in yeast. EMBO J (1992) 3.72
High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc Natl Acad Sci U S A (1989) 3.45
Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol Cell Biol (1995) 3.02
Expression of human fibroblast growth factor 2 mRNA is post-transcriptionally controlled by a unique destabilizing element present in the 3'-untranslated region between alternative polyadenylation sites. J Biol Chem (1999) 2.65
Two independent internal ribosome entry sites are involved in translation initiation of vascular endothelial growth factor mRNA. Mol Cell Biol (1998) 2.59
Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor. Mol Cell Biol (1991) 2.47
Nucleolin functions in the first step of ribosomal RNA processing. EMBO J (1998) 2.35
Basic fibroblast growth factor enters the nucleolus and stimulates the transcription of ribosomal genes in ABAE cells undergoing G0----G1 transition. Proc Natl Acad Sci U S A (1987) 2.27
The glycine-rich domain of nucleolin has an unusual supersecondary structure responsible for its RNA-helix-destabilizing properties. J Biol Chem (1992) 2.07
Detection of vascular endothelial growth factor messenger RNA and vascular endothelial growth factor-like activity in proliferative diabetic retinopathy. Arch Ophthalmol (1994) 2.00
Detection and localization of a class of proteins immunologically related to a 100-kDa nucleolar protein. Eur J Biochem (1982) 1.99
Molecular cloning of Xenopus fibrillarin, a conserved U3 small nuclear ribonucleoprotein recognized by antisera from humans with autoimmune disease. Mol Cell Biol (1990) 1.91
Translocation of bFGF to the nucleus is G1 phase cell cycle specific in bovine aortic endothelial cells. EMBO J (1990) 1.85
Nucleolin interacts with several ribosomal proteins through its RGG domain. J Biol Chem (1998) 1.77
Structure of the mouse nucleolin gene. The complete sequence reveals that each RNA binding domain is encoded by two independent exons. J Mol Biol (1988) 1.76
Nucleolin is a sequence-specific RNA-binding protein: characterization of targets on pre-ribosomal RNA. J Mol Biol (1996) 1.76
A powerful method for the preparation of cDNA libraries: isolation of cDNA encoding a 100-kDal nucleolar protein. Gene (1985) 1.74
Translation of CUG- but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells. J Cell Biol (1996) 1.73
RNA binding fragments from nucleolin contain the ribonucleoprotein consensus sequence. J Biol Chem (1987) 1.69
Protein and cDNA sequence of a glycine-rich, dimethylarginine-containing region located near the carboxyl-terminal end of nucleolin (C23 and 100 kDa). J Biol Chem (1986) 1.67
A major nucleolar protein, nucleolin, induces chromatin decondensation by binding to histone H1. Eur J Biochem (1988) 1.63
Viral RNA annealing activities of the nucleocapsid protein of Moloney murine leukemia virus are zinc independent. Nucleic Acids Res (1991) 1.61
A new 34-kilodalton isoform of human fibroblast growth factor 2 is cap dependently synthesized by using a non-AUG start codon and behaves as a survival factor. Mol Cell Biol (1999) 1.61
Alternative translation initiation of the Moloney murine leukemia virus mRNA controlled by internal ribosome entry involving the p57/PTB splicing factor. J Biol Chem (1995) 1.54
Nucleolin from Xenopus laevis: cDNA cloning and expression during development. Genes Dev (1989) 1.52
Extracellular cleavage of the vascular endothelial growth factor 189-amino acid form by urokinase is required for its mitogenic effect. J Biol Chem (1997) 1.52
Prevention of fatty streak formation of 17beta-estradiol is not mediated by the production of nitric oxide in apolipoprotein E-deficient mice. Circulation (1997) 1.50
Estradiol accelerates reendothelialization in mouse carotid artery through estrogen receptor-alpha but not estrogen receptor-beta. Circulation (2001) 1.50
Interrelations between the maturation of a 100 kDa nucleolar protein and pre rRNA synthesis in CHO cells. Nucleic Acids Res (1984) 1.48
Gastric inhibitory polypeptide-dependent cortisol hypersecretion--a new cause of Cushing's syndrome. N Engl J Med (1992) 1.45
Fractionation of mitochondrial RNA from HeLa cells by high-resolution electrophoresis under strongly denaturing conditions. J Mol Biol (1978) 1.44
Production of monoclonal antibodies to human estrogen-receptor protein (ER) using recombinant ER (RER). Int J Cancer (1993) 1.42
Mitosis-specific phosphorylation of nucleolin by p34cdc2 protein kinase. Mol Cell Biol (1990) 1.40
Differential effects of interleukin-1 receptor antagonist and tumor necrosis factor binding protein on fatty-streak formation in apolipoprotein E-deficient mice. Circulation (1998) 1.40
The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice. Proc Natl Acad Sci U S A (2002) 1.38
Two RNA-binding domains determine the RNA-binding specificity of nucleolin. J Biol Chem (1997) 1.37
Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin. J Biol Chem (1996) 1.34
Is the coiled body involved in nucleolar functions? Exp Cell Res (1994) 1.33
Protein kinase NII and the regulation of rDNA transcription in mammalian cells. Nucleic Acids Res (1989) 1.31
Estradiol alters nitric oxide production in the mouse aorta through the alpha-, but not beta-, estrogen receptor. Circ Res (2002) 1.29
Effects of heat shock on gene expression and subcellular protein distribution in Chinese hamster ovary cells. Nucleic Acids Res (1979) 1.28
New vascular endothelial growth factor isoform generated by internal ribosome entry site-driven CUG translation initiation. Mol Endocrinol (2001) 1.28
Concerted activities of the RNA recognition and the glycine-rich C-terminal domains of nucleolin are required for efficient complex formation with pre-ribosomal RNA. Eur J Biochem (1992) 1.28
Repeat peptide motifs which contain beta-turns and modulate DNA condensation in chromatin. Eur J Biochem (1990) 1.24
Phosphorylation of nucleolin by a nucleolar type NII protein kinase. Biochemistry (1987) 1.23
Cloning of the hexA mismatch-repair gene of Streptococcus pneumoniae and identification of the product. Gene (1985) 1.23
Localization of nucleolin binding sites on human and mouse pre-ribosomal RNA. Biochimie (1996) 1.21
[Effect of supra-optimal temperature on nucleolar ribonucleoproteins and RNA. II. Biochemical study]. Exp Cell Res (1969) 1.21
New ways of initiating translation in eukaryotes. Mol Cell Biol (2001) 1.20
cis-acting elements involved in the alternative translation initiation process of human basic fibroblast growth factor mRNA. Mol Cell Biol (1992) 1.20
Involvement of interleukin-6 in atherosclerosis but not in the prevention of fatty streak formation by 17beta-estradiol in apolipoprotein E-deficient mice. Atherosclerosis (2001) 1.17
Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2. Proc Natl Acad Sci U S A (1994) 1.16
Interaction of nucleolin with an evolutionarily conserved pre-ribosomal RNA sequence is required for the assembly of the primary processing complex. J Biol Chem (2000) 1.16
Determination of the functional domains involved in nucleolar targeting of nucleolin. Mol Biol Cell (1993) 1.16
FIF [fibroblast growth factor-2 (FGF-2)-interacting-factor], a nuclear putatively antiapoptotic factor, interacts specifically with FGF-2. Mol Endocrinol (2000) 1.15
Electric field mediated transformation: isolation and characterization of a TK+ subclone. Biochem Biophys Res Commun (1985) 1.14
Identification of Streptococcus pneumoniae mismatch repair genes by an additive transformation approach. Mol Gen Genet (1984) 1.13
The hexB mismatch repair gene of Streptococcus pneumoniae: characterisation, cloning and identification of the product. Mol Gen Genet (1985) 1.13
The transplacental passage of prednisone and prednisolone in pregnancy near term. J Pediatr (1972) 1.12
Identification of a segment of the small nucleolar ribonucleoprotein-associated protein GAR1 that is sufficient for nucleolar accumulation. J Biol Chem (1994) 1.12
Human DNA helicase IV is nucleolin, an RNA helicase modulated by phosphorylation. Gene (1995) 1.12
Cytochemical and immunocytochemical characterization of nuclear bodies during hibernation. Eur J Cell Biol (1994) 1.11
Maturation of a 100 kDa protein associated with preribosomes in Chinese hamster ovary cells. Mol Biol Rep (1983) 1.10
17 beta-estradiol prevents fatty streak formation in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (1997) 1.10
Nucleolar distribution of proteins B23 and nucleolin in mouse preimplantation embryos as visualized by immunoelectron microscopy. Development (1990) 1.09
Nucleolin gene organization in rodents: highly conserved sequences within three of the 13 introns. Gene (1990) 1.08
RNA recognition by the joint action of two nucleolin RNA-binding domains: genetic analysis and structural modeling. EMBO J (1997) 1.07
Developmental expression of fibrillarin and U3 snRNA in Xenopus laevis. Development (1991) 1.07
Role of phosphorylation on the maturation pathways of a 100 kDa nucleolar protein. FEBS Lett (1983) 1.07
Cytoplasmic and nuclear estradiol and progesterone receptors in human endometrium. J Clin Endocrinol Metab (1978) 1.06
Physicochemical and genetic evidence for specific antiestrogen binding sites. Proc Natl Acad Sci U S A (1983) 1.06
Ultrastructural analysis of nucleolar transcription in cells microinjected with 5-bromo-UTP. Histochem Cell Biol (2000) 1.06
Possible role of protein phosphorylation in the mitogenic effect of high density lipoproteins on cultured vascular endothelial cells. J Biol Chem (1986) 1.06
Synergistic effect of histone H1 and nucleolin on chromatin condensation in mitosis: role of a phosphorylated heteromer. Biochemistry (1991) 1.06
Detection of superoxide anion released extracellularly by endothelial cells using cytochrome c reduction, ESR, fluorescence and lucigenin-enhanced chemiluminescence techniques. Free Radic Biol Med (2000) 1.06
Two different combinations of RNA-binding domains determine the RNA binding specificity of nucleolin. J Biol Chem (2001) 1.05
Alternative initiation of translation accounts for a 67/45 kDa dimorphism of the human estrogen receptor ERalpha. Biochem Biophys Res Commun (1999) 1.05
Fibroblast growth factor-2 interacts with free ribosomal protein S19. Biochem Biophys Res Commun (2001) 1.05
Heterogeneity of endothelial cells: the specialized phenotype of human high endothelial venules characterized by suppression subtractive hybridization. Am J Pathol (1999) 1.04
Hypoxia-microRNA-16 downregulation induces VEGF expression in anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphomas. Leukemia (2011) 1.04
Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production. Proc Natl Acad Sci U S A (1996) 1.04
Nucleolin is an Ag-NOR protein; this property is determined by its amino-terminal domain independently of its phosphorylation state. Exp Cell Res (1992) 1.04
[Effect of supra-optimal temperature on nucleolar ribonucleoproteins and RNA. 1. Ultrastructural study]. Exp Cell Res (1969) 1.02
Cell transformation results in the loss of the density-dependent translational regulation of the expression of fibroblast growth factor 2 isoforms. Cancer Res (1999) 1.01
Cloning of cDNA encoding a 100 kDa nucleolar protein (nucleoline) of Chinese hamster ovary cells. Nucleic Acids Res (1985) 1.01
Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2 delays photoreceptor cell degeneration in Royal College of Surgeons rats. Proc Natl Acad Sci U S A (1999) 0.99
Inhibition of fibroblast growth factor 2 expression by antisense RNA induced a loss of the transformed phenotype in a human hepatoma cell line. Cancer Res (1995) 0.98