Published in Nature on February 15, 1990
An analysis of vertebrate mRNA sequences: intimations of translational control. J Cell Biol (1991) 12.00
Tat-mediated delivery of heterologous proteins into cells. Proc Natl Acad Sci U S A (1994) 5.00
Downstream secondary structure facilitates recognition of initiator codons by eukaryotic ribosomes. Proc Natl Acad Sci U S A (1990) 3.95
Alternative translation of human fibroblast growth factor 2 mRNA occurs by internal entry of ribosomes. Mol Cell Biol (1995) 3.02
Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid. EMBO J (1991) 2.84
A new translational regulator with homology to eukaryotic translation initiation factor 4G. EMBO J (1997) 2.66
Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor. Mol Cell Biol (1991) 2.47
The pim-1 oncogene encodes two related protein-serine/threonine kinases by alternative initiation at AUG and CUG. EMBO J (1991) 2.26
cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. Proc Natl Acad Sci U S A (1991) 2.16
The immediate downstream codon strongly influences the efficiency of utilization of eukaryotic translation initiation codons. EMBO J (1994) 1.93
Expression of the Epstein-Barr virus BamHI A fragment in nasopharyngeal carcinoma: evidence for a viral protein expressed in vivo. J Virol (1991) 1.91
Positions +5 and +6 can be major determinants of the efficiency of non-AUG initiation codons for protein synthesis. EMBO J (1994) 1.90
Alternative translation of osteopontin generates intracellular and secreted isoforms that mediate distinct biological activities in dendritic cells. Proc Natl Acad Sci U S A (2008) 1.77
pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation. Proc Natl Acad Sci U S A (1998) 1.74
Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promote apoptotic cell death. Mol Cell Biol (1995) 1.73
Purification and cDNA cloning of SAPKK3, the major activator of RK/p38 in stress- and cytokine-stimulated monocytes and epithelial cells. EMBO J (1996) 1.68
Transgenes expressing the Wnt-1 and int-2 proto-oncogenes cooperate during mammary carcinogenesis in doubly transgenic mice. Mol Cell Biol (1992) 1.62
The membrane-associated and secreted forms of the respiratory syncytial virus attachment glycoprotein G are synthesized from alternative initiation codons. J Virol (1994) 1.52
Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation. Biochem J (1997) 1.49
Non-AUG initiation of AGAMOUS mRNA translation in Arabidopsis thaliana. Mol Cell Biol (1999) 1.47
Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. Mol Cell Biol (1993) 1.44
Heat shock induces the release of fibroblast growth factor 1 from NIH 3T3 cells. Proc Natl Acad Sci U S A (1992) 1.44
Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptides. Proc Natl Acad Sci U S A (1997) 1.43
Endogenous interleukin 1 alpha must be transported to the nucleus to exert its activity in human endothelial cells. Mol Cell Biol (1994) 1.42
Two isoforms of murine hck, generated by utilization of alternative translational initiation codons, exhibit different patterns of subcellular localization. Mol Cell Biol (1991) 1.41
Alternative usage of initiation codons in mRNA encoding the cAMP-responsive-element modulator generates regulators with opposite functions. Proc Natl Acad Sci U S A (1992) 1.39
The rat hepatic leukemia factor (HLF) gene encodes two transcriptional activators with distinct circadian rhythms, tissue distributions and target preferences. EMBO J (1995) 1.36
Characterization of a family of endogenous neuropeptide ligands for the G protein-coupled receptors GPR7 and GPR8. Proc Natl Acad Sci U S A (2003) 1.33
The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo. Br J Cancer (2000) 1.33
Midkine induces the transformation of NIH3T3 cells. Br J Cancer (1997) 1.33
Competition between nuclear localization and secretory signals determines the subcellular fate of a single CUG-initiated form of FGF3. EMBO J (1994) 1.32
RAR-beta 4, a retinoic acid receptor isoform is generated from RAR-beta 2 by alternative splicing and usage of a CUG initiator codon. Proc Natl Acad Sci U S A (1992) 1.27
Growth factors in the nucleolus? J Cell Biol (1998) 1.27
Translation of equine infectious anemia virus bicistronic tat-rev mRNA requires leaky ribosome scanning of the tat CTG initiation codon. J Virol (1993) 1.26
Expression of the c-kit protein in human solid tumors and in corresponding fetal and adult normal tissues. Am J Pathol (1993) 1.26
The parainfluenza virus type 1 P/C gene uses a very efficient GUG codon to start its C' protein. J Virol (1992) 1.25
The Drosophila erect wing gene, which is important for both neuronal and muscle development, encodes a protein which is similar to the sea urchin P3A2 DNA binding protein. Mol Cell Biol (1993) 1.24
Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4. Mol Cell Biol (2000) 1.24
Intracellular osteopontin (iOPN) and immunity. Immunol Res (2011) 1.23
cis-acting elements involved in the alternative translation initiation process of human basic fibroblast growth factor mRNA. Mol Cell Biol (1992) 1.20
Potential oncogenic effects of basic fibroblast growth factor requires cooperation between CUG and AUG-initiated forms. Cell Regul (1991) 1.17
Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon. J Cell Biol (1992) 1.13
Methylation of high molecular weight fibroblast growth factor-2 determines post-translational increases in molecular weight and affects its intracellular distribution. Mol Biol Cell (1996) 1.12
Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus. Mol Cell Biol (1992) 1.10
Molecular mechanisms of fibroblast growth factor signaling in physiology and pathology. Cold Spring Harb Perspect Biol (2013) 1.10
Identification of a cysteine-rich receptor for fibroblast growth factors. Mol Cell Biol (1992) 1.10
Biosynthesis of human fibroblast growth factor-5. Mol Cell Biol (1991) 1.09
Expression of transforming growth factor alpha, amphiregulin and cripto-1 in human breast carcinomas. Br J Cancer (1994) 1.09
Selective expression of high molecular weight basic fibroblast growth factor confers a unique phenotype to NIH 3T3 cells. Cell Regul (1991) 1.07
Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system. Proc Natl Acad Sci U S A (1992) 1.05
Functional analysis of the AUG- and CUG-initiated forms of the c-Myc protein. Mol Biol Cell (1994) 1.04
Signaling by fibroblast growth factors: the inside story. Sci STKE (2001) 1.04
A Regression-Based Analysis of Ribosome-Profiling Data Reveals a Conserved Complexity to Mammalian Translation. Mol Cell (2015) 1.04
New sites of proviral integration associated with murine promonocytic leukemias and evidence for alternate modes of c-myb activation. J Virol (1992) 1.01
Thyroid hormone receptor transcriptional activity is potentially autoregulated by truncated forms of the receptor. Mol Cell Biol (1992) 1.00
Cathepsin D gene is controlled by a mixed promoter, and estrogens stimulate only TATA-dependent transcription in breast cancer cells. Proc Natl Acad Sci U S A (1993) 0.98
Nucleolar association of fibroblast growth factor 3 via specific sequence motifs has inhibitory effects on cell growth. Mol Cell Biol (1995) 0.97
Nuclear activities of basic fibroblast growth factor: potentiation of low-serum growth mediated by natural or chimeric nuclear localization signals. Mol Biol Cell (1999) 0.94
Brain-derived neurotrophic factor: subcellular compartmentalization and interneuronal transfer as visualized with anti-peptide antibodies. Proc Natl Acad Sci U S A (1991) 0.94
An Outer Mitochondrial Translocase, Tom22, Is Crucial for Inner Mitochondrial Steroidogenic Regulation in Adrenal and Gonadal Tissues. Mol Cell Biol (2016) 0.92
Direct evidence for methylation of arginine residues in high molecular weight forms of basic fibroblast growth factor. Cell Regul (1991) 0.90
Synthesis and secretion of transforming growth factor beta isoforms by primary cultures of human breast tumour fibroblasts in vitro and their modulation by tamoxifen. Br J Cancer (1996) 0.88
Structural and functional characterization of rev-like transcripts of equine infectious anemia virus. J Virol (1993) 0.87
Cell transformation by kFGF requires secretion but not glycosylation. J Cell Biol (1991) 0.87
Selection of CUG and AUG initiator codons for Drosophila E74A translation depends on downstream sequences. Proc Natl Acad Sci U S A (1993) 0.86
Noncanonical translation initiation of the Arabidopsis flowering time and alternative polyadenylation regulator FCA. Plant Cell (2010) 0.85
Expression of int-2 oncogene in Kaposi's sarcoma lesions. J Clin Invest (1993) 0.85
The Int-2/Fgf-3 oncogene product is secreted and associates with extracellular matrix: implications for cell transformation. Mol Cell Biol (1991) 0.85
Alanyl-tRNA synthetase genes of Vanderwaltozyma polyspora arose from duplication of a dual-functional predecessor of mitochondrial origin. Nucleic Acids Res (2011) 0.84
FGF3 from Xenopus laevis. EMBO J (1993) 0.84
Retention of fibroblast growth factor 3 in the Golgi complex may regulate its export from cells. Mol Cell Biol (1993) 0.83
Two species of Rev proteins, with distinct N termini, are expressed by caprine arthritis encephalitis virus. J Virol (1996) 0.81
Physical and biochemical properties of mammalian DNase X proteins: non-AUG translation initiation of porcine and bovine mRNAs for DNase X. Biochem J (2005) 0.81
Analysis of mutations in the putative nuclear localization sequence of interleukin-1 beta. Biochem J (1991) 0.80
Divergent Alanyl-tRNA Synthetase Genes of Vanderwaltozyma polyspora Descended from a Common Ancestor through Whole-Genome Duplication Followed by Asymmetric Evolution. Mol Cell Biol (2015) 0.78
MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA. PLoS One (2016) 0.75
Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids. Neoplasia (2017) 0.75
Nasal carriage as a source of Staphylococcus aureus bacteremia. Study Group. N Engl J Med (2001) 14.84
The reduction of nitrates in animal tissues. Biochem J (1928) 9.91
Studies on xanthine oxidase: Xanthine oxidase and lactoflavine. Biochem J (1934) 8.11
The properties of pure glutathione. Biochem J (1930) 7.82
FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J Virol (1982) 6.11
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J (1998) 6.08
Evidence for autolysin-mediated primary attachment of Staphylococcus epidermidis to a polystyrene surface. Mol Microbiol (1997) 5.47
Adherence and growth of coagulase-negative staphylococci on surfaces of intravenous catheters. J Infect Dis (1982) 5.40
Yeast lactic dehydrogenase and cytochrome b(2). Biochem J (1946) 4.90
p14ARF links the tumour suppressors RB and p53. Nature (1998) 4.78
Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16. Nature (1995) 4.78
Regulation of p16CDKN2 expression and its implications for cell immortalization and senescence. Mol Cell Biol (1996) 4.67
Mice lacking cyclin D1 are small and show defects in eye and mammary gland development. Genes Dev (1995) 4.64
The p16INK4a/CDKN2A tumor suppressor and its relatives. Biochim Biophys Acta (1998) 4.45
Studies on mustard gas (betabeta'-dichlorodiethyl sulphide) and some related compounds: 5. The fate of injected mustard gas (containing radioactive sulphur) in the animal body. Biochem J (1946) 4.41
Complete nucleotide sequence of a milk-transmitted mouse mammary tumor virus: two frameshift suppression events are required for translation of gag and pol. J Virol (1987) 4.37
An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis. Development (2000) 4.33
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence. Nature (2001) 4.14
Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus. EMBO J (1986) 4.08
Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer. Adv Cancer Res (1996) 3.89
Tumorigenesis by mouse mammary tumor virus: evidence for a common region for provirus integration in mammary tumors. Cell (1983) 3.89
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res (1994) 3.65
Persistent infection with small colony variant strains of Staphylococcus aureus in patients with cystic fibrosis. J Infect Dis (1998) 3.61
Tumorigenesis by mouse mammary tumor virus: proviral activation of a cellular gene in the common integration region int-2. Cell (1984) 3.61
Establishing stimulus equivalences among retarded adolescents. J Exp Child Psychol (1976) 3.55
Microbial colonization of prosthetic devices. II. Scanning electron microscopy of naturally infected intravenous catheters. Zentralbl Bakteriol Mikrobiol Hyg B (1981) 3.53
A site-directed Staphylococcus aureus hemB mutant is a small-colony variant which persists intracellularly. J Bacteriol (1997) 3.25
Methicillin-resistant Staphylococcus aureus (MRSA): burden of disease and control challenges in Europe. Euro Surveill (2010) 3.15
Fibronectin, fibrinogen, and laminin act as mediators of adherence of clinical staphylococcal isolates to foreign material. J Infect Dis (1988) 3.09
Learning and memory difficulties after environmental exposure to waterways containing toxin-producing Pfiesteria or Pfiesteria-like dinoflagellates. Lancet (1998) 3.03
Low-molecular-weight RNAs of Moloney murine leukemia virus: identification of the primer for RNA-directed DNA synthesis. J Virol (1977) 2.99
Specific binding of tryptophan transfer RNA to avian myeloblastosis virus RNA-dependent DNA polymerase (reverse transcriptase). Proc Natl Acad Sci U S A (1975) 2.97
Studies on xanthine oxidase. X: The action of light. Biochem J (1928) 2.94
Recovery of small colony variants of Staphylococcus aureus following gentamicin bead placement for osteomyelitis. Clin Infect Dis (1997) 2.82
Interference with granulocyte function by Staphylococcus epidermidis slime. Infect Immun (1986) 2.80
EBNA-2 and EBNA-LP cooperate to cause G0 to G1 transition during immortalization of resting human B lymphocytes by Epstein-Barr virus. EMBO J (1994) 2.79
Intravenous cefotaxime in children with bacterial meningitis. Lancet (1980) 2.77
Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair. Gut (1999) 2.68
Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus. Nat Cell Biol (2001) 2.66
A 140-kilodalton extracellular protein is essential for the accumulation of Staphylococcus epidermidis strains on surfaces. Infect Immun (1997) 2.65
Rapid and specific detection of toxigenic Staphylococcus aureus: use of two multiplex PCR enzyme immunoassays for amplification and hybridization of staphylococcal enterotoxin genes, exfoliative toxin genes, and toxic shock syndrome toxin 1 gene. J Clin Microbiol (1998) 2.60
Moving the research agenda to where it matters. BMJ (1999) 2.58
CDK6 (PLSTIRE) and CDK4 (PSK-J3) are a distinct subset of the cyclin-dependent kinases that associate with cyclin D1. Oncogene (1994) 2.55
Staphylococcus aureus RN6390 replicates and induces apoptosis in a pulmonary epithelial cell line. Infect Immun (2000) 2.54
Potential oncogene product related to growth factors. Nature (1987) 2.53
Inhibitors of cyclin-dependent kinases induce features of replicative senescence in early passage human diploid fibroblasts. Curr Biol (1998) 2.42
The graphical determination of K m and K i . Biochem J (1972) 2.38
Effect of extracellular slime substance from Staphylococcus epidermidis on the human cellular immune response. Lancet (1984) 2.35
Does 'healing' benefit patients with chronic symptoms? A quasi-randomized trial in general practice. J R Soc Med (1998) 2.26
Lack of cyclin D-Cdk complexes in Rb-negative cells correlates with high levels of p16INK4/MTS1 tumour suppressor gene product. EMBO J (1995) 2.26
Randomized controlled trial of an educational booklet for patients presenting with back pain in general practice. J R Coll Gen Pract (1989) 2.25
Concerted activation of two potential proto-oncogenes in carcinomas induced by mouse mammary tumour virus. Nature (1986) 2.24
D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1. Oncogene (1991) 2.21
Fibroblast growth factor receptor 2-IIIb acts upstream of Shh and Fgf4 and is required for limb bud maintenance but not for the induction of Fgf8, Fgf10, Msx1, or Bmp4. Dev Biol (2001) 2.21
Prevention of osteoporosis in glucocorticoid-treated neurology patients. Clin Neurol Neurosurg (2005) 2.19
Intracellular persistence of Staphylococcus aureus small-colony variants within keratinocytes: a cause for antibiotic treatment failure in a patient with darier's disease. Clin Infect Dis (2001) 2.14
Protein A is the von Willebrand factor binding protein on Staphylococcus aureus. Blood (2000) 2.12
Cyclin D1 and prognosis in human breast cancer. Int J Cancer (1996) 2.11
Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells. Infect Immun (2000) 2.11
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. Nature (1997) 2.10
Increased expression of clumping factor and fibronectin-binding proteins by hemB mutants of Staphylococcus aureus expressing small colony variant phenotypes. Infect Immun (2002) 2.08
Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J (1988) 2.08
The measurement of tissue glycolysis in serum. II. Biochem J (1937) 2.08
CD4(+) T cells and the proinflammatory cytokines gamma interferon and interleukin-6 contribute to alveolar bone loss in mice. Infect Immun (1999) 2.05
Over-the-counter drugs for children. Lancet (1994) 2.03
Absence of cyclin D/cdk complexes in cells lacking functional retinoblastoma protein. Oncogene (1994) 1.99
Microbial colonization of prosthetic devices. III. Adhesion of staphylococci to lumina of intravenous catheters perfused with bacterial suspensions. Zentralbl Bakteriol Mikrobiol Hyg B (1981) 1.97
Pathogenesis and management of Staphylococcus epidermidis 'plastic' foreign body infections. J Antimicrob Chemother (1984) 1.96
Microbial colonization of prosthetic devices. I. Microtopographical characteristics of intravenous catheters as detected by scanning electron microscopy. Zentralbl Bakteriol Mikrobiol Hyg B (1981) 1.95
The action of sodium cromoglycate on 'C' fibre endings in the dog lung. Br J Pharmacol (1980) 1.95
Morphological and biochemical characterization of viral particles produced by the tsO45 mutant of vesicular stomatitis virus at restrictive temperature. J Virol (1979) 1.93
RNA-directed DNA synthesis in Moloney murine leukemia virus: interaction between the primer tRNA and the genome RNA. J Virol (1979) 1.92
Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene. Mol Cell Biol (1986) 1.90
Complex structure and regulation of the P16 (MTS1) locus. Cancer Res (1995) 1.87
Protein-coding potential of mouse mammary tumor virus genome RNA as examined by in vitro translation. J Virol (1981) 1.87
The int-2 gene product acts as an epithelial growth factor in transgenic mice. EMBO J (1990) 1.82
Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis. Gut (1996) 1.82
Staphylococcal small colony variants have novel mechanisms for antibiotic resistance. Clin Infect Dis (1998) 1.81
Systematic literature analysis and review of targeted preventive measures to limit healthcare-associated infections by meticillin-resistant Staphylococcus aureus. Euro Surveill (2014) 1.79
In vitro synthesis of polypeptides encoded by the long terminal repeat region of mouse mammary tumour virus DNA. Nature (1981) 1.77
Chromosome 11q13 abnormalities in human cancer. Cancer Cells (1991) 1.74
Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer. Oncogene (1990) 1.69