Published in FEBS Lett on March 31, 2006
From carbohydrate leads to glycomimetic drugs. Nat Rev Drug Discov (2009) 2.13
DC-SIGN neck domain is a pH-sensor controlling oligomerization: SAXS and hydrodynamic studies of extracellular domain. J Biol Chem (2009) 1.02
Non-carbohydrate inhibitors of the lectin DC-SIGN. J Am Chem Soc (2007) 0.91
Glycosaminoglycans are interactants of Langerin: comparison with gp120 highlights an unexpected calcium-independent binding mode. PLoS One (2012) 0.84
Nanotechnology and the treatment of HIV infection. Viruses (2012) 0.84
A review of nanotechnological approaches for the prophylaxis of HIV/AIDS. Biomaterials (2013) 0.83
Nanoparticle-based drug delivery to the vagina: a review. J Control Release (2014) 0.83
Structural characterization of the DC-SIGN-Lewis(X) complex. Biochemistry (2014) 0.79
Evaluation of the synthesis of sialic acid-PAMAM glycodendrimers without the use of sugar protecting groups, and the anti-HIV-1 properties of these compounds. Bioconjug Chem (2011) 0.79
Inhibition binding studies of glycodendrimer-lectin interactions using surface plasmon resonance. Tetrahedron (2010) 0.78
Linear biocompatible glyco-polyamidoamines as dual action mode virus infection inhibitors with potential as broad-spectrum microbicides for sexually transmitted diseases. Sci Rep (2016) 0.75
"Rules of Engagement" of Protein-Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular Modeling. ChemistryOpen (2016) 0.75
Synthesis of Lewis(X)-O-Core-1 threonine: A building block for O-linked Lewis(X) glycopeptides. Carbohydr Res (2017) 0.75
Dendritic-cell-specific ICAM3-grabbing non-integrin is essential for the productive infection of human dendritic cells by mosquito-cell-derived dengue viruses. EMBO Rep (2003) 3.29
DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2. J Biol Chem (2003) 2.82
Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection. Immunity (2002) 2.42
Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells. Blood (2002) 1.60
Cellular glycosaminoglycans and low density lipoprotein receptor are involved in hepatitis C virus adsorption. J Med Virol (2002) 1.55
NADPH oxidase activator p67(phox) behaves in solution as a multidomain protein with semi-flexible linkers. J Struct Biol (2009) 1.54
Interaction of the mitotic inhibitor monastrol with human kinesin Eg5. Biochemistry (2003) 1.51
Heparan sulfate/heparin oligosaccharides protect stromal cell-derived factor-1 (SDF-1)/CXCL12 against proteolysis induced by CD26/dipeptidyl peptidase IV. J Biol Chem (2004) 1.51
Grid-type metal ion architectures: functional metallosupramolecular arrays. Angew Chem Int Ed Engl (2004) 1.50
Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus. Virology (2002) 1.48
Synthesis of giant globular multivalent glycofullerenes as potent inhibitors in a model of Ebola virus infection. Nat Chem (2016) 1.46
Analysis of recent pediatric orthotopic liver transplantation outcomes indicates that allograft type is no longer a predictor of survivals. Liver Transpl (2008) 1.46
Multivalent glycoconjugates as anti-pathogenic agents. Chem Soc Rev (2012) 1.41
Heparan sulfate targets the HIV-1 envelope glycoprotein gp120 coreceptor binding site. J Biol Chem (2005) 1.38
The cell adhesion molecule "CAR" and sialic acid on human erythrocytes influence adenovirus in vivo biodistribution. PLoS Pathog (2009) 1.37
Two microtubule-associated proteins of Arabidopsis MAP65s promote antiparallel microtubule bundling. Mol Biol Cell (2008) 1.35
Hepatitis C virus core protein is a dimeric alpha-helical protein exhibiting membrane protein features. J Virol (2005) 1.34
A synthetic CD4-heparan sulfate glycoconjugate inhibits CCR5 and CXCR4 HIV-1 attachment and entry. Nat Chem Biol (2009) 1.25
Bacteriorhodopsin/amphipol complexes: structural and functional properties. Biophys J (2008) 1.24
Structural and mutational analysis of human Ad37 and canine adenovirus 2 fiber heads in complex with the D1 domain of coxsackie and adenovirus receptor. J Biol Chem (2006) 1.23
NMR structure and ion channel activity of the p7 protein from hepatitis C virus. J Biol Chem (2010) 1.21
Gold Glyconanoparticles as Water-Soluble Polyvalent Models To Study Carbohydrate Interactions This work was supported by the DGICYT (PB96-0820), J.M.F. thanks the MEC for a predoctoral fellowship. A.G.B. thanks CSIC for financial support. We thank Prof. Martín-Lomas for his scientific and financial support. Angew Chem Int Ed Engl (2001) 1.21
Heparan sulfate proteoglycans are receptors for the cell-surface trafficking and biological activity of transglutaminase-2. J Biol Chem (2009) 1.17
Partial specific volume and solvent interactions of amphipol A8-35. Anal Biochem (2004) 1.16
Anti-activator ExsD forms a 1:1 complex with ExsA to inhibit transcription of type III secretion operons. J Biol Chem (2009) 1.15
The HIV-1 envelope glycoprotein gp120 features four heparan sulfate binding domains, including the co-receptor binding site. J Biol Chem (2008) 1.15
Effects of p47phox C terminus phosphorylations on binding interactions with p40phox and p67phox. Structural and functional comparison of p40phox and p67phox SH3 domains. J Biol Chem (2005) 1.14
The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4. PLoS One (2007) 1.14
Relationships between glycosaminoglycan and receptor binding sites in chemokines-the CXCL12 example. Carbohydr Res (2008) 1.11
Adenovirus protein involved in virus internalization recruits ubiquitin-protein ligases. Biochemistry (2002) 1.11
Inflammatory chemokines direct and restrict leukocyte migration within live tissues as glycan-bound gradients. Curr Biol (2012) 1.11
Conformation of heparin studied with macromolecular hydrodynamic methods and X-ray scattering. Eur Biophys J (2003) 1.10
An archaeal peptidase assembles into two different quaternary structures: A tetrahedron and a giant octahedron. J Biol Chem (2006) 1.09
Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1. Proc Natl Acad Sci U S A (2013) 1.08
Characterization of endostatin binding to heparin and heparan sulfate by surface plasmon resonance and molecular modeling: role of divalent cations. J Biol Chem (2003) 1.07
Structural view of glycosaminoglycan-protein interactions. Carbohydr Res (2006) 1.07
Oligomeric states of the detergent-solubilized human serum paraoxonase (PON1). J Biol Chem (2002) 1.06
Small-angle X-ray scattering reveals the solution structure of the full-length DNA gyrase a subunit. Structure (2005) 1.05
Least median of squares filtering of locally optimal point matches for compressible flow image registration. Phys Med Biol (2012) 1.05
Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia. Circulation (2012) 1.03
The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins. PLoS One (2008) 1.02
Mannosyl glycodendritic structure inhibits DC-SIGN-mediated Ebola virus infection in cis and in trans. Antimicrob Agents Chemother (2003) 1.02
DC-SIGN neck domain is a pH-sensor controlling oligomerization: SAXS and hydrodynamic studies of extracellular domain. J Biol Chem (2009) 1.02
Human immunodeficiency virus and heparan sulfate: from attachment to entry inhibition. Front Immunol (2013) 1.01
The fucose-binding lectin from Ralstonia solanacearum. A new type of beta-propeller architecture formed by oligomerization and interacting with fucoside, fucosyllactose, and plant xyloglucan. J Biol Chem (2005) 1.01
Normal human keratinocytes bind to the alpha3LG4/5 domain of unprocessed laminin-5 through the receptor syndecan-1. J Biol Chem (2003) 1.01
Homeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions. Circulation (2012) 1.01
Structural studies of langerin and Birbeck granule: a macromolecular organization model. Biochemistry (2009) 1.00
A kinetics and modeling study of RANTES(9-68) binding to heparin reveals a mechanism of cooperative oligomerization. Biochemistry (2002) 1.00
Well-defined nanoparticles formed by hydrophobic assembly of a short and polydisperse random terpolymer, amphipol A8-35. Langmuir (2006) 0.99
Synthesis of tailor-made glycoconjugate mimetics of heparan sulfate that bind IFN-gamma in the nanomolar range. Chemistry (2004) 0.98
Isolation and characterisation of the rabies virus N degrees-P complex produced in insect cells. Virology (2003) 0.97
Modular structure of the full-length DNA gyrase B subunit revealed by small-angle X-ray scattering. Structure (2007) 0.96
Heparan sulphate proteoglycans and viral vectors : ally or foe? Curr Gene Ther (2006) 0.95
Inhibition of DC-SIGN-mediated HIV infection by a linear trimannoside mimic in a tetravalent presentation. ACS Chem Biol (2010) 0.95
Adenovirus dodecahedron cell attachment and entry are mediated by heparan sulfate and integrins and vary along the cell cycle. Virology (2007) 0.95
Direct peptide interaction with surface glycosaminoglycans contributes to the cell penetration of maurocalcine. J Biol Chem (2008) 0.95
Identification of tubular heparan sulfate as a docking platform for the alternative complement component properdin in proteinuric renal disease. J Biol Chem (2010) 0.95
Purification of Na+,K+-ATPase expressed in Pichia pastoris reveals an essential role of phospholipid-protein interactions. J Biol Chem (2005) 0.95
Factor h and properdin recognize different epitopes on renal tubular epithelial heparan sulfate. J Biol Chem (2012) 0.95
Heparan sulfate proteoglycan mediates the selective attachment and internalization of serotype 3 human adenovirus dodecahedron. Virology (2004) 0.95
Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infection. Nat Commun (2012) 0.94
Cutting edge: C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain. J Immunol (2010) 0.94
Optimized purification of a heterodimeric ABC transporter in a highly stable form amenable to 2-D crystallization. PLoS One (2011) 0.94
Analytical ultracentrifugation sedimentation velocity for the characterization of detergent-solubilized membrane proteins Ca++-ATPase and ExbB. J Biol Phys (2008) 0.94
The Oligomeric states of Haloarcula marismortui malate dehydrogenase are modulated by solvent components as shown by crystallographic and biochemical studies. J Mol Biol (2003) 0.93
PatA and PatB form a functional heterodimeric ABC multidrug efflux transporter responsible for the resistance of Streptococcus pneumoniae to fluoroquinolones. Biochemistry (2012) 0.93
Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2. Proc Natl Acad Sci U S A (2002) 0.93
Synergy between extracellular modules of vascular endothelial cadherin promotes homotypic hexameric interactions. J Biol Chem (2002) 0.93
Polypyrrole oligosaccharide array and surface plasmon resonance imaging for the measurement of glycosaminoglycan binding interactions. Anal Chem (2008) 0.93
Leukotriene BLT2 receptor monomers activate the G(i2) GTP-binding protein more efficiently than dimers. J Biol Chem (2009) 0.93
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action. Br J Pharmacol (2011) 0.92
Mitochondrial bovine ADP/ATP carrier in detergent is predominantly monomeric but also forms multimeric species. Biochemistry (2008) 0.92
A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency. J Biol Chem (2009) 0.92
Small-angle X-ray scattering reveals an extended organization for the autoinhibitory resting state of the p47(phox) modular protein. Biochemistry (2006) 0.92
Leu505 of Nox2 is crucial for optimal p67phox-dependent activation of the flavocytochrome b558 during phagocytic NADPH oxidase assembly. J Leukoc Biol (2006) 0.92
Tyrosine dephosphorylation of the syndecan-1 PDZ binding domain regulates syntenin-1 recruitment. J Biol Chem (2009) 0.92
Heparan sulfate mimicry: a synthetic glycoconjugate that recognizes the heparin binding domain of interferon-gamma inhibits the cytokine activity. J Biol Chem (2005) 0.91
Low resolution structure determination shows procollagen C-proteinase enhancer to be an elongated multidomain glycoprotein. J Biol Chem (2002) 0.91
The ABC transporter BmrA from Bacillus subtilis is a functional dimer when in a detergent-solubilized state. Biochem J (2006) 0.91
Trapping and stabilization of integral membrane proteins by hydrophobically grafted glucose-based telomers. Biomacromolecules (2009) 0.91
Characterization of the elongasome core PBP2 : MreC complex of Helicobacter pylori. Mol Microbiol (2011) 0.91
Regulation of NADPH oxidase activity in phagocytes: relationship between FAD/NADPH binding and oxidase complex assembly. J Biol Chem (2010) 0.89
Lactobionamide surfactants with hydrogenated, perfluorinated or hemifluorinated tails: physical-chemical and biochemical characterization. Langmuir (2006) 0.89
1,2-Mannobioside mimic: synthesis, DC-SIGN interaction by NMR and docking, and antiviral activity. ChemMedChem (2007) 0.89
Small angle neutron scattering for the study of solubilised membrane proteins. Eur Phys J E Soft Matter (2013) 0.89
A glycomimetic compound inhibits DC-SIGN-mediated HIV infection in cellular and cervical explant models. AIDS (2012) 0.88