Published in Mol Microbiol on August 01, 1991
PCR mapping of integrons reveals several novel combinations of resistance genes. Antimicrob Agents Chemother (1995) 12.54
Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. Microbiol Rev (1993) 9.38
PCR detection of metallo-beta-lactamase gene (blaIMP) in gram-negative rods resistant to broad-spectrum beta-lactams. J Clin Microbiol (1996) 6.68
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes. Nucleic Acids Res (2005) 6.61
Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae. Antimicrob Agents Chemother (2000) 6.37
Expression of antibiotic resistance genes in the integrated cassettes of integrons. Antimicrob Agents Chemother (1995) 6.26
A novel integron-like element carrying the metallo-beta-lactamase gene blaIMP. Antimicrob Agents Chemother (1995) 6.00
Multifocal outbreaks of metallo-beta-lactamase-producing Pseudomonas aeruginosa resistant to broad-spectrum beta-lactams, including carbapenems. Antimicrob Agents Chemother (1996) 5.36
Transposon Tn21, flagship of the floating genome. Microbiol Mol Biol Rev (1999) 4.65
Site-specific deletion and rearrangement of integron insert genes catalyzed by the integron DNA integrase. J Bacteriol (1992) 4.39
Structure of In31, a blaIMP-containing Pseudomonas aeruginosa integron phyletically related to In5, which carries an unusual array of gene cassettes. Antimicrob Agents Chemother (1999) 4.24
The 3' conserved segment of integrons contains a gene associated with multidrug resistance to antiseptics and disinfectants. Antimicrob Agents Chemother (1993) 3.80
GES-2, a class A beta-lactamase from Pseudomonas aeruginosa with increased hydrolysis of imipenem. Antimicrob Agents Chemother (2001) 3.39
OXA-11, an extended-spectrum variant of OXA-10 (PSE-2) beta-lactamase from Pseudomonas aeruginosa. Antimicrob Agents Chemother (1993) 3.09
Integrons found in different locations have identical 5' ends but variable 3' ends. J Bacteriol (1994) 2.89
Class 1 integron-borne multiple-antibiotic resistance carried by IncFI and IncL/M plasmids in Salmonella enterica serotype typhimurium. Antimicrob Agents Chemother (1998) 2.78
Transposons Tn1696 and Tn21 and their integrons In4 and In2 have independent origins. Antimicrob Agents Chemother (2001) 2.70
Characterization of In53, a class 1 plasmid- and composite transposon-located integron of Escherichia coli which carries an unusual array of gene cassettes. J Bacteriol (2001) 2.68
Characterisation of specific and secondary recombination sites recognised by the integron DNA integrase. Nucleic Acids Res (1994) 2.55
The integrons In0, In2, and In5 are defective transposon derivatives. J Bacteriol (1996) 2.53
blaCTX-M-2 is located in an unusual class 1 integron (In35) which includes Orf513. Antimicrob Agents Chemother (2002) 2.47
New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pBWH301. Antimicrob Agents Chemother (1995) 2.41
Family of class 1 integrons related to In4 from Tn1696. Antimicrob Agents Chemother (2001) 2.41
OXA-15, an extended-spectrum variant of OXA-2 beta-lactamase, isolated from a Pseudomonas aeruginosa strain. Antimicrob Agents Chemother (1997) 2.28
Molecular characterization of integrons in Acinetobacter baumannii: description of a hybrid class 2 integron. Antimicrob Agents Chemother (2000) 2.25
Characterization of Salmonella enterica serovar typhimurium DT104 isolated from Denmark and comparison with isolates from Europe and the United States. J Clin Microbiol (2000) 2.10
Genetic characterization of antimicrobial resistance in Canadian isolates of Salmonella serovar Typhimurium DT104. Antimicrob Agents Chemother (1999) 2.03
Revised analysis of aadA2 gene of plasmid pSa. Antimicrob Agents Chemother (1994) 2.03
A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100. Antimicrob Agents Chemother (1991) 1.98
IntI2 integron integrase in Tn7. J Bacteriol (2002) 1.95
Molecular characterization of OXA-20, a novel class D beta-lactamase, and its integron from Pseudomonas aeruginosa. Antimicrob Agents Chemother (1998) 1.94
Characterization and movement of the class 1 integron known as Tn2521 and Tn1405. Antimicrob Agents Chemother (2002) 1.71
Characterization of In40 of Enterobacter aerogenes BM2688, a class 1 integron with two new gene cassettes, cmlA2 and qacF. Antimicrob Agents Chemother (1998) 1.68
Nosocomial spread of ceftazidime-resistant Klebsiella pneumoniae strains producing a novel class a beta-lactamase, GES-3, in a neonatal intensive care unit in Japan. Antimicrob Agents Chemother (2004) 1.65
Integron cassette insertion: a recombination process involving a folded single strand substrate. EMBO J (2005) 1.62
Efficiency of recombination reactions catalyzed by class 1 integron integrase IntI1. J Bacteriol (2001) 1.55
Presence of a group II intron in a multiresistant Serratia marcescens strain that harbors three integrons and a novel gene fusion. Antimicrob Agents Chemother (2002) 1.53
A novel dihydrofolate reductase cassette inserted in an integron borne on a Tn21-like element. Antimicrob Agents Chemother (1993) 1.51
Characterization of the 6'-N-aminoglycoside acetyltransferase gene aac(6')-Im [corrected] associated with a sulI-type integron. Antimicrob Agents Chemother (1997) 1.51
Characterization and chromosomal mapping of antimicrobial resistance genes in Salmonella enterica serotype typhimurium. Appl Environ Microbiol (2000) 1.46
Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate. Antimicrob Agents Chemother (2002) 1.43
Cholera in Vietnam: changes in genotypes and emergence of class I integrons containing aminoglycoside resistance gene cassettes in vibrio cholerae O1 strains isolated from 1979 to 1996. J Clin Microbiol (1999) 1.37
Rapid screening technique for class 1 integrons in Enterobacteriaceae and nonfermenting gram-negative bacteria and its use in molecular epidemiology. Antimicrob Agents Chemother (2001) 1.35
Characterization of transposon Tn5086, carrying the site-specifically inserted gene dhfrVII mediating trimethoprim resistance. J Bacteriol (1993) 1.35
Characterization of the class 3 integron and the site-specific recombination system it determines. J Bacteriol (2002) 1.34
Class 1 integron containing a new gene cassette, aadA10, associated with Tn1404 from R151. Antimicrob Agents Chemother (2002) 1.34
Characterization of the aac(6')-Ib gene encoding an aminoglycoside 6'-N-acetyltransferase in Pseudomonas aeruginosa BM2656. Antimicrob Agents Chemother (1993) 1.34
Molecular characterization of a new class 3 integron in Klebsiella pneumoniae. Antimicrob Agents Chemother (2003) 1.33
Molecular characterization of Irish Salmonella enterica serotype typhimurium: detection of class I integrons and assessment of genetic relationships by DNA amplification fingerprinting. Appl Environ Microbiol (2000) 1.31
Sequence of the MIR-1 beta-lactamase gene. Antimicrob Agents Chemother (1999) 1.30
Increased prevalence of class I integrons in Escherichia coli, Klebsiella species, and Enterobacter species isolates over a 7-year period in a German university hospital. J Clin Microbiol (2001) 1.23
Integrons: past, present, and future. Microbiol Mol Biol Rev (2014) 1.23
Characterization of multidrug-resistant Salmonella enterica serovar Typhimurium isolated in Japan. J Clin Microbiol (2001) 1.21
Genetic rearrangement associated with in vivo mucoid conversion of Pseudomonas aeruginosa PAO is due to insertion elements. J Bacteriol (1994) 1.21
Point mutations in the integron integrase IntI1 that affect recombination and/or substrate recognition. J Bacteriol (1998) 1.20
The IntI1 integron integrase preferentially binds single-stranded DNA of the attC site. J Bacteriol (1999) 1.20
Integron integrases possess a unique additional domain necessary for activity. J Bacteriol (2001) 1.18
Salmonella enterica serovar Typhimurium bla(PER-1)-carrying plasmid pSTI1 encodes an extended-spectrum aminoglycoside 6'-N-acetyltransferase of type Ib. Antimicrob Agents Chemother (2003) 1.18
Molecular characterization of the OXA-7 beta-lactamase gene. Antimicrob Agents Chemother (1995) 1.16
Structural features of single-stranded integron cassette attC sites and their role in strand selection. PLoS Genet (2009) 1.15
Integration and excision of a 2,4-dichlorophenoxyacetic acid-degradative plasmid in Alcaligenes paradoxus and evidence of its natural intergeneric transfer. J Bacteriol (1994) 1.12
Class 1 integron-associated tobramycin-gentamicin resistance in Campylobacter jejuni isolated from the broiler chicken house environment. Antimicrob Agents Chemother (2002) 1.11
Novel streptomycin and spectinomycin resistance gene as a gene cassette within a class 1 integron isolated from Escherichia coli. Antimicrob Agents Chemother (1999) 1.09
A hot spot in plasmid F for site-specific recombination mediated by Tn21 integron integrase. J Bacteriol (1997) 1.08
Aminoglycoside resistance genes aph(2")-Ib and aac(6')-Im detected together in strains of both Escherichia coli and Enterococcus faecium. Antimicrob Agents Chemother (2001) 1.07
Cloning and characterization of a 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ib, from Pseudomonas aeruginosa. Antimicrob Agents Chemother (1995) 1.07
Recombination activity of a distinctive integron-gene cassette system associated with Pseudomonas stutzeri populations in soil. J Bacteriol (2003) 1.07
Roles of horizontal gene transfer and gene integration in evolution of 1,3-dichloropropene- and 1,2-dibromoethane-degradative pathways. J Bacteriol (2000) 1.05
Integron integrase binds to bulged hairpin DNA. Nucleic Acids Res (2004) 1.04
Evolution of the chloroplast genome. Philos Trans R Soc Lond B Biol Sci (2003) 1.03
Insights and inferences about integron evolution from genomic data. BMC Genomics (2008) 1.02
New gene cassettes for trimethoprim resistance, dfr13, and Streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron. Antimicrob Agents Chemother (2000) 0.97
QRDR mutations, efflux system & antimicrobial resistance genes in enterotoxigenic Escherichia coli isolated from an outbreak of diarrhoea in Ahmedabad, India. Indian J Med Res (2011) 0.96
A new in vitro strand transfer assay for monitoring bacterial class 1 integron recombinase IntI1 activity. PLoS One (2007) 0.94
Characterization of the 6'-N-aminoglycoside acetyltransferase gene aac(6')-Iq from the integron of a natural multiresistance plasmid. Antimicrob Agents Chemother (1998) 0.94
ACID: annotation of cassette and integron data. BMC Bioinformatics (2009) 0.93
Functional characterization of Tn1331 gene cassettes. J Antimicrob Chemother (2008) 0.92
A family of insertion sequences that impacts integrons by specific targeting of gene cassette recombination sites, the IS1111-attC Group. J Bacteriol (2008) 0.92
Recovery of a functional class 2 integron from an Escherichia coli strain mediating a urinary tract infection. Antimicrob Agents Chemother (2008) 0.92
Distribution of class II transposase and resolvase genes in soil bacteria and their association with mer genes. Appl Environ Microbiol (1996) 0.91
Different pathways to acquiring resistance genes illustrated by the recent evolution of IncW plasmids. Antimicrob Agents Chemother (2008) 0.91
Conduction of pEC22, a plasmid coding for MR.EcoT22I, mediated by a resident Tn3-like transposon, Tn5396. J Bacteriol (1994) 0.90
New enzymes from environmental cassette arrays: functional attributes of a phosphotransferase and an RNA-methyltransferase. Protein Sci (2004) 0.89
Analysis of the aac(3)-VIa gene encoding a novel 3-N-acetyltransferase. Antimicrob Agents Chemother (1993) 0.89
Cellular pathways controlling integron cassette site folding. EMBO J (2010) 0.88
In vitro recombination catalyzed by bacterial class 1 integron integrase IntI1 involves cooperative binding and specific oligomeric intermediates. PLoS One (2009) 0.86
Replicative resolution of integron cassette insertion. Nucleic Acids Res (2012) 0.86
Gene integration in the Escherichia coli chromosome mediated by Tn21 integrase (Int21). J Bacteriol (1996) 0.85
Diversity and strength of internal outward-oriented promoters in group IIC-attC introns. Nucleic Acids Res (2010) 0.85
Integrase-mediated recombination of the veb1 gene cassette encoding an extended-spectrum β-lactamase. PLoS One (2012) 0.84
Class I integron with a group II intron detected in an Escherichia coli strain from a free-range reindeer. Antimicrob Agents Chemother (2005) 0.84
Effect of attC structure on cassette excision by integron integrases. Mob DNA (2011) 0.83
Reconstruction of an active integron recombination site after integration of a gene cassette at a secondary site. Antimicrob Agents Chemother (1999) 0.83
Group IIC intron mobility into attC sites involves a bulged DNA stem-loop motif. RNA (2009) 0.82
Using genomic data to determine the diversity and distribution of target site motifs recognized by class C-attC group II introns. J Mol Evol (2009) 0.82
Identification and analysis of integrons and cassette arrays in bacterial genomes. Nucleic Acids Res (2016) 0.82
Potential role of group IIC-attC introns in integron cassette formation. J Bacteriol (2009) 0.82
Correctly identifying the streptothricin resistance gene cassette. J Clin Microbiol (2005) 0.82
Worldwide prevalence of class 2 integrases outside the clinical setting is associated with human impact. Appl Environ Microbiol (2009) 0.81
The integron integrase efficiently prevents the melting effect of Escherichia coli single-stranded DNA-binding protein on folded attC sites. J Bacteriol (2013) 0.81
Site-specific insertion of gene cassettes into integrons. Mol Microbiol (1993) 2.91
Integrons found in different locations have identical 5' ends but variable 3' ends. J Bacteriol (1994) 2.89
Transposons Tn1696 and Tn21 and their integrons In4 and In2 have independent origins. Antimicrob Agents Chemother (2001) 2.70
Characterisation of specific and secondary recombination sites recognised by the integron DNA integrase. Nucleic Acids Res (1994) 2.55
The integrons In0, In2, and In5 are defective transposon derivatives. J Bacteriol (1996) 2.53
New mobile gene cassettes containing an aminoglycoside resistance gene, aacA7, and a chloramphenicol resistance gene, catB3, in an integron in pBWH301. Antimicrob Agents Chemother (1995) 2.41
Family of class 1 integrons related to In4 from Tn1696. Antimicrob Agents Chemother (2001) 2.41
Integrons: mobilizable platforms that promote genetic diversity in bacteria. Trends Microbiol (2007) 2.14
Multidrug resistance in Klebsiella pneumoniae: a novel gene, ramA, confers a multidrug resistance phenotype in Escherichia coli. Microbiology (1995) 2.05
A new trimethoprim resistance gene, dhfrX, in the In7 integron of plasmid pDGO100. Antimicrob Agents Chemother (1991) 1.98
Binding of the purified integron DNA integrase Intl1 to integron- and cassette-associated recombination sites. Mol Microbiol (1998) 1.93
Integrons: novel DNA elements which capture genes by site-specific recombination. Genetica (1993) 1.93
Definition of the attI1 site of class 1 integrons. Microbiology (2000) 1.83
The evolution of class 1 integrons and the rise of antibiotic resistance. J Bacteriol (2008) 1.83
Mobile gene cassettes and integrons in evolution. Ann N Y Acad Sci (1999) 1.83
Recovery of new integron classes from environmental DNA. FEMS Microbiol Lett (2001) 1.76
Efficiency of recombination reactions catalyzed by class 1 integron integrase IntI1. J Bacteriol (2001) 1.55
The gene cassette metagenome is a basic resource for bacterial genome evolution. Environ Microbiol (2003) 1.52
Characterization of the class 3 integron and the site-specific recombination system it determines. J Bacteriol (2002) 1.34
Mobile gene cassettes: a fundamental resource for bacterial evolution. Am Nat (2004) 1.34
Integron-encoded IntI integrases preferentially recognize the adjacent cognate attI site in recombination with a 59-be site. Mol Microbiol (2002) 1.31
Integrons in Xanthomonas: a source of species genome diversity. Proc Natl Acad Sci U S A (2005) 1.30
The structure of a partial duplication in the integron of plasmid pDGO100. Plasmid (1990) 1.29
Complementation analysis in Pseudomonas aeruginosa of the transfer genes of the wide host range R plasmid R18. Plasmid (1981) 1.28
Recovery and evolutionary analysis of complete integron gene cassette arrays from Vibrio. BMC Evol Biol (2006) 1.23
Nucleotide sequence of the aceB gene encoding malate synthase A in Escherichia coli. Nucleic Acids Res (1988) 1.23
Integron-associated gene cassettes in Halifax Harbour: assessment of a mobile gene pool in marine sediments. Environ Microbiol (2008) 1.11
Urinary tract infections in a South American population: dynamic spread of class 1 integrons and multidrug resistance by homologous and site-specific recombination. J Clin Microbiol (2008) 1.10
Comparison of plasmids in strains of Zymomonas mobilis. Plasmid (1983) 1.09
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Gene cassettes encoding resistance to quaternary ammonium compounds: a role in the origin of clinical class 1 integrons? ISME J (2008) 1.05
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Dissemination of multiple drug resistance genes by class 1 integrons in Klebsiella pneumoniae isolates from four countries: a comparative study. Antimicrob Agents Chemother (2011) 1.03
Use of chromosomal integron arrays as a phylogenetic typing system for Vibrio cholerae pandemic strains. Microbiology (2007) 1.02
Unique genome arrangement of an ovine adenovirus: identification of new proteins and proteinase cleavage sites. Virology (1996) 1.01
Recombination between the dfrA12-orfF-aadA2 cassette array and an aadA1 gene cassette creates a hybrid cassette, aadA8b. Antimicrob Agents Chemother (2005) 1.01
A class 1 integron present in a human commensal has a hybrid transposition module compared to Tn402: evidence of interaction with mobile DNA from natural environments. J Bacteriol (2008) 1.01
Mobilization of a Tn402-like class 1 integron with a novel cassette array via flanking miniature inverted-repeat transposable element-like structures. Appl Environ Microbiol (2009) 0.99
A putative house-cleaning enzyme encoded within an integron array: 1.8 A crystal structure defines a new MazG subtype. Mol Microbiol (2007) 0.98
Coral-mucus-associated Vibrio integrons in the Great Barrier Reef: genomic hotspots for environmental adaptation. ISME J (2011) 0.97
Genetic context and structural diversity of class 1 integrons from human commensal bacteria in a hospital intensive care unit. Antimicrob Agents Chemother (2011) 0.94
Identification of a chloroplast-encoded secA gene homologue in a chromophytic alga: possible role in chloroplast protein translocation. Curr Genet (1992) 0.94
Evidence for dynamic exchange of qac gene cassettes between class 1 integrons and other integrons in freshwater biofilms. FEMS Microbiol Lett (2009) 0.94
Novel and diverse integron integrase genes and integron-like gene cassettes are prevalent in deep-sea hydrothermal vents. Environ Microbiol (2007) 0.92
Identification of bla(CMY-7) and associated plasmid-mediated resistance genes in multidrug-resistant Escherichia coli isolated from dogs at a veterinary teaching hospital in Australia. J Antimicrob Chemother (2006) 0.92
Recovery of a functional class 2 integron from an Escherichia coli strain mediating a urinary tract infection. Antimicrob Agents Chemother (2008) 0.92
Improving protein solubility: the use of the Escherichia coli dihydrofolate reductase gene as a fusion reporter. Protein Expr Purif (2005) 0.92
Diverse mobilized class 1 integrons are common in the chromosomes of pathogenic Pseudomonas aeruginosa clinical isolates. Antimicrob Agents Chemother (2012) 0.90
Tn6060, a transposon from a genomic island in a Pseudomonas aeruginosa clinical isolate that includes two class 1 integrons. Antimicrob Agents Chemother (2009) 0.90
Indigenous Vibrio cholerae strains from a non-endemic region are pathogenic. Open Biol (2013) 0.89
New enzymes from environmental cassette arrays: functional attributes of a phosphotransferase and an RNA-methyltransferase. Protein Sci (2004) 0.89
Genome sequence of Vibrio rotiferianus strain DAT722. J Bacteriol (2011) 0.88
Crystal structure of an integron gene cassette-associated protein from Vibrio cholerae identifies a cationic drug-binding module. PLoS One (2011) 0.86
Preclinical class 1 integron with a complete Tn402-like transposition module. Appl Environ Microbiol (2010) 0.86
Heat shock Hsp70 protein is chloroplast-encoded in the chromophytic alga Pavlova lutherii. Plant Mol Biol (1992) 0.85
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A tissue-specific enhancer of the prostate-specific membrane antigen gene, FOLH1. Genomics (2001) 0.84
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Nucleotide sequence of ovine adenovirus tripartite leader sequence and homologues of the IVa2, DNA polymerase and terminal proteins. Gene (1996) 0.81
Integrons or super integrons? Microbiology (2004) 0.80
Class 1 integron-associated spread of resistance regions in Pseudomonas aeruginosa: plasmid or chromosomal platforms? J Antimicrob Chemother (2012) 0.80
Characterisation of a chloroplast-encoded secY homologue and atpH from a chromophytic alga. Evidence for a novel chloroplast genome organisation. FEBS Lett (1992) 0.80
Integron-associated mobile gene cassettes code for folded proteins: the structure of Bal32a, a new member of the adaptable alpha+beta barrel family. J Mol Biol (2004) 0.79
Integron gene cassettes: a repository of novel protein folds with distinct interaction sites. PLoS One (2013) 0.79
What are superintegrons? Nat Rev Microbiol (2007) 0.78
Characterisation of a chloramphenicol acetyltransferase determinant found in the chromosome of Pseudomonas aeruginosa. FEMS Microbiol Lett (1999) 0.78
Induced expression of a Drosophila hsp70 promoter-fusion transgene is reduced after repeated heat shocks. Genet Res (1992) 0.78
Deletion of integron-associated gene cassettes impact on the surface properties of Vibrio rotiferianus DAT722. PLoS One (2013) 0.78
Integron associated mobile genes: Just a collection of plug in apps or essential components of cell network hardware? Mob Genet Elements (2012) 0.78
Nucleotide sequence of the aceB gene encoding malate synthase A in Escherichia coli. Nucleic Acids Res (1988) 0.78
In vitro transposon mutagenesis of an equine herpesvirus 1 genome cloned as a bacterial artificial chromosome. Arch Virol (2006) 0.76
Survival of a lacZY-marked strain of Pseudomonas corrugata following a field release. FEMS Microbiol Ecol (2003) 0.75